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Megyn Kelly hosts a discussion on transitioning and de-transitioning, featuring Walt Heyer and Grace Ladinsky-Smith, both of whom regret their transitions. Walt transitioned to Laura Jensen in his forties but de-transitioned after realizing he needed therapy for childhood trauma rather than surgery. He recounts how adverse childhood experiences, including emotional and sexual abuse, influenced his decision to transition. He emphasizes that many individuals who transition may be dealing with unresolved trauma rather than genuine gender dysphoria. Grace, who began questioning her gender in her twenties, underwent a double mastectomy and hormone therapy but later recognized her mistake. She describes her experience as being influenced by social media and a mental health crisis, leading her to believe that transitioning would resolve her issues. Both Walt and Grace face backlash from trans activists for sharing their stories, highlighting the societal pressure to affirm transitions without exploring underlying psychological issues. The conversation shifts to the medical perspective, with Dr. Julia Mason and Dr. Erica Anderson discussing the implications of puberty blockers and cross-sex hormones. They outline significant risks associated with these treatments, including bone density issues, cognitive effects, and irreversible changes to sexual function. They express concern over the lack of thorough evaluations before medical interventions are prescribed, noting that many young people may be seeking transition as a solution to broader psychological problems. The discussion also touches on the increasing number of young girls identifying as trans and the potential societal factors influencing this trend. Both doctors advocate for a more cautious approach, emphasizing the need for individualized assessments and addressing underlying mental health issues rather than rushing into medical treatments. They call for a systematic review of the scientific evidence surrounding these practices, similar to actions taken in countries like Sweden and Finland, which have begun to reassess their approaches to gender-affirming care for minors.

Dr. James Cantor discusses paraphilia, defining it as innate sexual interest patterns that can be profound and immutable, such as exhibitionism and pedophilia. He emphasizes that these interests are distinct from typical sexual orientations and often debated in terms of their classification. Asexuality is explored as a complex label that can signify low sex drive or serve social functions, but it can also be adopted by individuals avoiding insecurities. Cantor highlights the "older brother effect," where the likelihood of male homosexuality increases with the number of older brothers, suggesting a maternal immune response to male fetuses. He notes that while male homosexuality has biological underpinnings, female sexuality is more context-dependent and influenced by relational factors. The conversation shifts to the stigma surrounding pedophilia, differentiating between the sexual attraction pattern and criminal behavior. Cantor argues that many who identify as pedophiles do not act on their attractions and often struggle with societal condemnation, which drives them underground instead of seeking help. He discusses the complexities of transgender identities, noting that while gender identity is not located in the brain, there are neurological patterns associated with sexual orientation and atypical sexualities. Cantor expresses concern over the rapid acceptance of transitioning in children without sufficient evidence of long-term outcomes, advocating for more robust research and therapy. The dialogue touches on the intersection of mental health and suicidality among transgender youth, emphasizing that the high rates of suicidal ideation do not necessarily correlate with the need for medical interventions. Cantor calls for a reevaluation of the medical establishment's approach to transitioning, advocating for evidence-based practices and caution against hasty decisions that could have lasting consequences.

On Origins Podcast, Lauren Schwarz and Arthur Rousseau discuss their chapter in The War on Science, focusing on gender-affirming care (GAC) and medical standards. They argue that the World Professional Association for Transgender Health (WPATH) wields influence, with U.S. medical bodies deferring to it, while the UK’s Cass report and countries have begun to curtail such care. They describe WPATH’s standards of care (SOC 8) as presenting itself as evidence-based, lifesaving care, yet note published reviews finding the strength of the evidence often low or indirect, and that guidelines are not always consistent with the underlying literature. They recount that Johns Hopkins underwent political pressure to withdraw systematic reviews and that WPATH later imposed an approval mechanism over future publications. The speakers condemn the reliance on “lived experience” over rigorous evidence, and highlight concerns about age restrictions being removed and consent for minors to hormonal or surgical interventions. They cite a lack of long-term outcome data, no conclusive evidence that gender-affirming care reduces suicide, and cases illustrating the risks of messaging to afraid families. They call for better education, transparency, and a return to science-based medicine, while referencing the Tennessee minors’ care case and urging global alignment.

In this episode of The Megyn Kelly Show, Dr. Lisa Littman discusses her research on the surge of transgender identification among teenagers, particularly girls, which she terms "rapid onset gender dysphoria." Dr. Littman, a physician and researcher at Brown University, observed a statistically unusual increase in teenagers, especially girls, identifying as transgender and sought to study the phenomenon. Her findings suggest that social and peer influences may play a significant role in these identifications, leading to concerns about a potential social contagion effect. Dr. Littman faced significant backlash from trans activists and some members of the medical community, who accused her of bigotry and conducting shoddy science. Despite this, she received support from many parents who felt their children were being rushed into transitions without adequate evaluation. Her research indicated that many of the teenagers identifying as transgender had pre-existing mental health issues, raising questions about the underlying causes of their gender dysphoria. She emphasizes the importance of thorough evaluations before transitioning, noting that many detransitioners reported feeling pressured by healthcare providers to pursue medical interventions. Dr. Littman highlights the need for a balanced discussion about gender dysphoria, advocating for the inclusion of diverse experiences and cautioning against the oversimplification of the issue. The conversation also touches on the role of social media in shaping perceptions of gender identity among youth, with many parents reporting that their children were influenced by online communities. Dr. Littman calls for a more nuanced understanding of gender dysphoria that considers various factors, including mental health and social dynamics, rather than solely affirming a child's self-identification. She concludes by stressing the need for open dialogue and research to ensure that young people receive appropriate care and support.