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Sexual health is a crucial aspect of overall well-being, serving as a biomarker for physical and mental health. Good sexual function indicates effective nervous system signaling and blood flow, while issues like erectile dysfunction (ED) in men can signal deeper health problems, such as cardiovascular issues. The penis and clitoris share embryonic origins, and both can indicate vascular health. For women, sexual arousal and desire are complex and influenced by biological, psychological, and social factors. Recent medical texts have updated the understanding of female anatomy, revealing the clitoris's extensive structure, which is solely for pleasure. Maintaining vaginal health involves understanding natural body functions and avoiding over-washing, which can disrupt the microbiome. Concerns about heavy metals in tampons and other products highlight the importance of understanding exposure levels and their potential health impacts. Urinary tract infections (UTIs) can be influenced by hormonal changes, especially during menopause, and hydration is key to prevention. Stress can also lead to pelvic floor dysfunction, complicating urinary health. Education about pelvic floor health, including Kegel exercises, is essential for both men and women to maintain function and prevent issues like incontinence. Erectile dysfunction affects a significant percentage of older men, with various causes including hormonal, psychological, and medication-related factors. Maintaining vascular health is crucial for erectile function. The discussion around circumcision remains contentious, with varying opinions on its impact on sensation and health risks. Open conversations about sexual health and education are vital for reducing stigma and improving overall intimacy and satisfaction in relationships. Understanding one’s body and maintaining a healthy dialogue about sexual health can lead to better outcomes and enhanced quality of life.

Six years ago, Robin Buckley bought her 13-year-old daughter a vibrator, sparking a journey to empower teenage girls about their bodies and pleasure. She highlights the need for open conversations about sex, as many girls learn about it from pornography. Understanding their bodies helps girls recognize health issues and assert their sexual needs. Empowering daughters fosters confidence, enabling them to advocate for themselves in all aspects of life.

Women often experience more shame discussing sex, with over half suffering from sexual dysfunction. The orgasm gap reveals that straight women climax less than 60% of the time compared to 90% for men. Misunderstandings of female sexuality persist, affecting education and consent. Empowering women to define their own pleasure is essential for equality and well-being.

In this episode of the Huberman Lab podcast, Dr. Rena Malik, a board-certified urologist and pelvic surgeon, discusses critical aspects of urinary, pelvic, and sexual health. The conversation covers common issues such as urinary tract infections (UTIs), pelvic floor dysfunction, and sexual dysfunction in both men and women. Dr. Malik explains that many people misunderstand pelvic floor health, often thinking they need to strengthen it when, in fact, some may need to relax it. A healthy pelvic floor supports functions like urination, defecation, and sexual activity. Dysfunction can manifest as urgency, frequency, pain during sex, or issues with bowel movements. Both over-tightening and weakness of the pelvic floor can lead to problems, and Dr. Malik emphasizes the importance of proper assessment by specialists. The discussion also delves into sexual health, differentiating between psychological desire and physical arousal. Dr. Malik highlights that hormone dysregulation is a minor factor in sexual dysfunction, while pelvic floor and blood flow issues are more significant contributors. She clarifies that many misconceptions exist around sexual health, particularly regarding the role of hormones. Dr. Malik addresses the importance of communication in sexual relationships, noting that many people lack the vocabulary to discuss their needs and preferences. She encourages open dialogue about sexual desires and experiences, emphasizing that understanding one’s own body and preferences is crucial for healthy sexual interactions. The episode also covers UTIs, which are more common in women, with up to 50% experiencing them in their lifetime. Dr. Malik discusses prevention strategies, such as hydration, proper hygiene, and the use of cranberry products, which can help reduce UTI risk. She also mentions that vaginal estrogen can be beneficial for postmenopausal women to maintain a healthy vaginal environment. The conversation touches on the impact of oral contraceptives on sexual health, noting that while they provide benefits like preventing pregnancy, they can also lead to sexual dysfunction in some women. Dr. Malik stresses the need for individualized approaches to contraception and sexual health. Dr. Malik discusses the rising trend of anal sex among heterosexual couples and emphasizes the importance of safety, consent, and communication. She explains that anal sex can be pleasurable but requires proper preparation and lubrication to avoid injury and reduce the risk of sexually transmitted infections. Finally, the episode highlights the connection between sexual dysfunction and overall health, particularly cardiovascular health. Dr. Malik advises that erectile dysfunction can be an early indicator of cardiovascular issues, urging men to seek medical advice if they experience such symptoms. She concludes by discussing lifestyle factors that can enhance sexual health, including diet, exercise, and stress management.

Correcting hormone imbalances is easier than living with them. Common imbalances include cortisol, insulin, estrogen dominance, testosterone issues, and growth hormone problems. High cortisol, often linked to stress, can lead to increased belly fat and disrupt other hormones. Hormones interact, creating patterns of imbalance. True health requires hormonal balance; without it, achieving health goals, like weight loss, is challenging. Symptoms of hormonal imbalances vary by hormone but can include fatigue, hair loss, constipation, and mood issues. Women are particularly vulnerable to these imbalances, but men also experience them. Mainstream medicine often overlooks hormone imbalances, focusing instead on medications like birth control or antidepressants without addressing root causes. Hormones influence many bodily functions, making their balance crucial. The conversation around hormone health is gaining traction, but many still don’t connect their symptoms to hormonal issues. Women’s unique hormonal cycles necessitate tailored approaches to health. For example, testosterone, often seen as a male hormone, is also vital for women, influencing mood and libido. Estradiol levels fluctuate significantly throughout a woman’s life, affecting mood and health. Growth hormone secretion differs between sexes, impacting metabolism. To address hormonal imbalances, focus on metabolism, which is influenced by diet and lifestyle. Continuous glucose monitors can help track metabolic health, allowing for personalized dietary adjustments. The Gottfried Protocol emphasizes detoxification, a well-formulated ketogenic diet, and intermittent fasting, particularly for women. Signs of improvement include increased satiety, weight loss, and better mood and relationships. Ultimately, understanding and taking control of one’s hormonal health is empowering. The book "Women, Food, and Hormones" aims to guide readers through this journey, emphasizing the importance of personalized approaches to diet and lifestyle for optimal hormonal balance.

If you are having sex with a woman for 5 to 6 minutes, 90% chance she's not orgasming, even if she sounds like she is. Dr. Reena Malik is introduced as willing to talk about taboo subjects with science and data backing. Are we having less sex than ever before? Absolutely. Studies show 40% of women faked an orgasm, and men also fake orgasms. The G-spot real? Really? The episode frames it as a zone, not a single button. If you exercise 150 minutes a week, moderate intensity cardiovascular exercise, it's as good as taking a Viagra. Women who watch porn and read those like kind of romance fantasy novels, it might increase our sex drive. First-time encounters show '45% of the time the woman's going to orgasm,' and in a lesbian first encounter, '95% of the time they organize.' The biggest myth is that the bigger the penis, the better the sex. '85% of women need clitoreral stimulation to climax.' It's not just about penetration; pleasure comes from stimulating other areas and the connection you have with your partner. Arousal for women takes about 25 minutes on average, while sex lasts around 5 to 6 minutes. Low libido is common: '40% of women will have low libido in their lifetime.' Testosterone drives desire and declines. There are two on-label options for premenopausal women: 'Atti'—a nightly pill that slowly increases desire—and 'Vissi,' an injection given 45 minutes before sex for a sudden boost. For men, erectile dysfunction is common: '52% of men over 50,' rising with age; '70% of ED is due to blood flow.' Exercise and heart health can improve ED; '150 minutes a week' of moderate cardio is as effective as Viagra. Mindfulness helps; '20 minutes of mindfulness outside the bedroom every day' yielded significant improvements across domains of female sexual function, with many continuing it a year later. The average age of first exposure to porn is '10.' Sensate focus is a technique to rebuild intimacy; pelvic floor health matters, with Keigles for weakness and therapy for tightness. Future questions include sex with robots, but human connection remains central.

The discussion centers on the female orgasm, its evolutionary significance, and its relationship with mate selection. David Puts suggests that the female orgasm may function in mate choice, potentially selecting for partners with high genetic quality or long-term investment capabilities. Research indicates that women with more masculine partners tend to orgasm more quickly and frequently, supporting the idea that orgasm may enhance conception likelihood. Puts also explores the role of oxytocin, released during orgasm, in fostering emotional closeness and possibly aiding sperm transport toward the egg. The conversation touches on the complexities of dominance in male competition, noting that while masculine traits may correlate with reproductive success, excessive dominance could be detrimental. Puts emphasizes the need for further research to clarify the relationship between orgasm and conception rates, proposing studies to investigate how orgasm influences fertility across different contexts. Additionally, the dialogue examines cognitive differences between genders, particularly in spatial abilities and memory, suggesting evolutionary roots for these traits. Puts highlights the significance of voice pitch in signaling dominance and attractiveness, noting that lower pitches are often perceived as indicators of fighting ability. The conversation concludes with a discussion on ongoing research into the effects of sex hormones on behavior and voice across cultures.

Imagination plays a crucial role in sexual arousal, often overlooked in favor of physical sensations. Women can enhance their desire through memories and fantasies. Gina Gutierrez emphasizes that sex is not solely a physical act but a mental experience, where individuals have the agency to create their own pleasure and narratives, fostering empowerment and confidence.

Peter Attia and Sally Greenwald delve into the critical, yet often overlooked, role of women's sexual health in overall well-being and longevity. Greenwald, an OBGYN specializing in sexual health, emphasizes that a healthy sex life contributes to better sleep through parasympathetic activation and neurotransmitter release (dopamine, oxytocin), improved cardiovascular health (mimicking moderate exercise), and enhanced mood and relationships. She highlights the significant "orgasm gap" between men (90-95% always orgasm with partners) and women (30% with partners, 12% in one-night stands), framing it as a health disparity that warrants greater attention. The discussion explores the nuances of female desire, distinguishing between spontaneous desire (more common in men) and responsive desire (more common in women), which can be cultivated through arousal, foreplay, and "chore play." Anatomical understanding is crucial, with Greenwald detailing the clitoris's extensive nerve structure, including the vestibule and crura, and the G-spot. She explains that less than 10% of women orgasm from penetrative intercourse alone, underscoring the importance of external clitoral stimulation and vibrators, especially as nerve fibers age. Practical advice for enhancing sexual health includes a "vaginal face analogy": consistent use of silicone-based, low-osmolality lubricants (like Uberlube or Good Clean Love) to prevent micro-abrasions and pain, regular vaginal moisturizers (Revaree, Replens), and targeted topical hormone therapy (local estrogen) when systemic hormones are insufficient. Hormonal interventions are also discussed, with testosterone cream recommended for hypoactive sexual desire disorder in post-menopausal women, and various estrogen/progesterone options for managing perimenopausal symptoms and contraception. Greenwald notes the limited efficacy of FDA-approved drugs like Addyi and Vyleesi compared to low-dose THC cannabis for arousal. The podcast also addresses the profound impact of adverse sexual experiences and trauma, advocating for sensate focus exercises and pelvic floor physical therapy. Sex during healthy pregnancy is deemed safe and potentially more pleasurable due to hormonal shifts, while postpartum care emphasizes addressing the hypoestrogenic state of lactation with local estrogen. Greenwald passionately calls for a reform in sex education, moving from fear-based to pleasure-based, anatomically accurate, and consent-focused content for all genders, to counter the unrealistic expectations set by pornography and foster healthier intimacy. She concludes by expressing optimism for personalized hormone therapy and integrating sexual satisfaction as a key longevity lever.

Almost none of the sex humans have is primarily reproductive; its main function is social behavior. Shane Parrish welcomes Emily Nagoski, a sex therapist and author of *Come As You Are*, to discuss various aspects of sexuality. Emily explains the difference between the vulva and vagina, emphasizing that both genders share similar anatomical structures, which are organized differently. She highlights the importance of using correct terminology to foster understanding and reduce shame around anatomy. Emily discusses societal discomfort with sex, attributing it to mixed messages about purity and shame. To improve conversations about sex, she advocates for early education and open discussions about body parts. She notes that cultural narratives often dictate that women's bodies are public property, complicating consent and reinforcing gender roles. The conversation touches on the impact of pornography on sexual education, noting that it often misrepresents sex and reinforces harmful norms. Emily emphasizes that while some people may use porn to cope with negative emotions, it can alienate partners and weaken connections. Regarding relationship dynamics, Emily explains that sex often diminishes in long-term relationships due to various life stresses. Couples who maintain a strong sexual connection prioritize intimacy and trust. She highlights that pleasure, rather than frequency, is the key measure of sexual well-being. Emily concludes by stressing that women have the same bodily autonomy as men and should not sacrifice their comfort for others. Understanding these dynamics can lead to healthier relationships and more fulfilling sexual experiences.

Dr. Jolene Brighten discusses the complexities of female sexual health, emphasizing the importance of understanding female anatomy, particularly the clitoris, which has about 10,000 nerve endings. She highlights the "orgasm gap," where men orgasm 95% of the time in heterosexual relationships compared to 65% for women. Many women engage in sex for emotional intimacy rather than just physical pleasure, complicating perceptions of libido. Brighten critiques traditional sex education, noting that many women lack knowledge about their bodies, often leading to misconceptions about libido and sexual function. She stresses the need for better communication between partners regarding sexual preferences and desires. The discussion includes the impact of societal norms on women's body image and sexual health, including the prevalence of surgeries like labiaplasty, which can lead to negative outcomes. Brighten also addresses the role of lubrication in enhancing sexual experiences, debunking myths about its necessity. She encourages open conversations about sexual fantasies and kinks, advocating for consent and understanding between partners. The conversation touches on the importance of addressing hormonal health and nutrition in relation to sexual well-being, emphasizing that many factors contribute to sexual satisfaction beyond mere physical stimulation. Overall, the dialogue aims to empower women and promote healthier sexual relationships through education and communication.

Joe Rogan and Lindsey Fitzharris discuss the gruesome history of medicine, focusing on Victorian surgical practices and the evolution of medical understanding. Fitzharris, a medical historian with a PhD, shares her fascination with historical medical failures, such as the "clockwork saw," an ineffective Victorian amputation tool. She highlights Joseph Lister's contributions to germ theory and antiseptics, which drastically improved surgical outcomes. Fitzharris explains that before Lister, surgeries often led to infections, and many patients died post-operation. She recounts the story of Robert Liston, a renowned surgeon known for his speed, who accidentally caused multiple fatalities during a single operation. The conversation touches on the public's morbid curiosity in the past, with people paying to witness surgeries, akin to modern-day reality shows. They discuss the historical context of medical practices, including the use of urine analysis for diagnosis and the bizarre anti-masturbation devices of the Victorian era. Fitzharris also mentions the origins of products like Listerine and Kellogg's Corn Flakes, both linked to health concerns of the time. The discussion shifts to the role of women in medicine, including Florence Nightingale's influence on nursing and sanitation, and the challenges faced by early medical practitioners. Fitzharris emphasizes the importance of learning from past failures in medicine and the ongoing evolution of medical practices. She concludes by promoting her book, "The Butchering Art," and her social media platforms, encouraging listeners to engage with her work on the history of medicine.

Theo Von announces new tour dates: a third London show on June 16th at the Eventim Apollo; New York City on May 31st; Belfast in the UK on June 6th (an added show; June 7th is sold out); Idaho Falls on June 27th (added); Salt Lake City on June 30th; and Las Vegas, Nevada on July 5th and 6th at Resorts World Las Vegas. Tickets are available at theoVon.com. If tickets are too expensive, “just wait, we’ll come back around.” They urge buying through the official link, not a secondary site. Thank you for the support. Today’s guest is a comedian, Theo’s friend, one of the roasters from the Tom Brady roast on Netflix, “one of the best roasters of all time.” Her new HBO special is Someday You’ll Die. Nikki Glazer. Nikki Glazer jokes about talking to women, saying, “the biggest fear inside of a man, I think, is talking to a woman.” She explains how comedy helped her feel like “one of the boys,” or at least not be treated differently, and notes she sometimes enjoys pulling out a feminine energy from men by letting them vent to her female friends. She imagines a devout lesbian who could shoulder some of a man’s burden, and she jokes about public reactions, relationships, and energy dynamics, riffing on concepts of masculine and feminine energy, sexuality, and charm. The discussion swerves into playful mockery of attractiveness standards, surgery, and the idea that money can buy near-perfect appearances, with Nikki saying she might reach a 9.2 with enough help and a right person, then acknowledging she already gets injections herself and enjoys the thrill of risk. Theo jokes about lips and fillers, posture, height, and how people notice posture and sexual confidence. They discuss body image and how women might project sexuality through posture, while acknowledging the physical toll of maintaining certain looks. A extended tangent about Toronto, civic attitudes, and global perceptions leads to broader reflections on consumer culture, borders, and national attitudes toward fame and wealth, intercut with jokes about vaccines, air travel, and border control. The conversation veers to sexuality and period talk, with Nikki answering questions about vaginal health and sex life: “pretty good,” with honest admission that her sex life has had ebbs and flows, including occasional insecurity about her appearance and the impact of cosmetic work. They discuss masturbation habits, dopamine cycles, and the psychology of sexual behavior, including how mood can affect desire and how some people engage in spirals of activity driven by dopamine. They pivot to mental health topics and even lobotomy in a frank, historical detour. Nikki explains what a lobotomy is—“a type of brain surgery that involves severing the connection between the frontal lobe and the other parts of the brain”—and they reference a 2018 study noting many lobotomized individuals were women, along with historical motivations like lack of initiative or restraint, and the role of hospital logic in those procedures. The back-and-forth touches on trauma, memory, dissociation, and the legacy of such practices, ending in a broader reflection about the ethics and evolution of treatments. The pair discuss social media life, online hate, filming in public, and how exposure changes personal interactions. They compare Comedy Central roasts and Netflix’s live format, noting the live element heightens risk and spontaneity, and discuss how clips and social media shape public perception. Nikki recalls the logistics of the Tom Brady roast, including Ben Affleck’s abrupt exit and the high-stakes premise of a single-bomb premise affecting the entire set. They reflect on the afterparty, fame, and the pressure to sustain momentum, then shift to creative work outside stand-up: Nikki’s new song, Someday You’ll Die, written the night before recording with a Chicago producer, and described as a pop song she believes could be a hit. She invites Theo to hear it, explains the songwriting process, and jokes about wanting to explore other skills like guitar and possibly DJing or violin. The episode closes with gratitude, admiration for Tom Brady’s presence, and mutual respect about what it means to rise to a new level of recognition, along with playful talk about future relationships, parenting, and the enduring thrill of creative risk.

Robert King, a former school teacher turned researcher, became interested in the study of female orgasm after reading Elizabeth Lloyd's book, which claimed it had no evolutionary function. He discovered two distinct traditions in the study of human sexuality: one that dismissed female orgasm as functionless and another that explored its potential roles. King criticized laboratory research methods, particularly those of Masters and Johnson, who studied female orgasm in a controlled environment, arguing that it failed to capture the complexity of human sexual behavior. He highlighted the pioneering work of the Foxes, who studied female orgasm in a more natural setting, discovering that it could enhance fertility through mechanisms like oxytocin-induced uterine contractions. King pointed out common misconceptions about female orgasm, such as the belief that women are psychologically broken or poorly designed by nature. He discussed the "byproduct theory," which suggests that female orgasm is merely a side effect of evolution, a notion popularized by paleontologist Stephen Jay Gould. King emphasized that the clitoris is not merely a small, functionless organ but a complex structure integral to female pleasure and orgasm. He argued that female orgasm is adaptive, linked to oxytocin release, which promotes bonding and may enhance reproductive success. He noted that the experience of orgasm varies among women, with factors like partner attractiveness and sexual dominance influencing outcomes. King's research found that the most significant predictor of female orgasm is the partner's smell, indicating genetic compatibility. He also discussed how women's sexual preferences are shaped by social dynamics, including competition among women for desirable partners. He pointed out that modern dating culture, influenced by social media, complicates sexual relationships and may contribute to a decline in sexual satisfaction. King concluded by addressing the complexities of female sexual agency, noting that women often navigate societal expectations while expressing their desires. He advocated for a more nuanced understanding of female sexuality, emphasizing the importance of recognizing women's active roles in sexual selection and their capacity for agency. His book, "Naturally Selective," explores these themes further.