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President Trump announces a historic, multi‑agency push to address the autism crisis. He cites rates rising from one in twenty thousand to one in thirty‑one overall, with one in twelve for boys in California, and says rates surged by more than four hundred percent since February. Acetaminophen during pregnancy is linked to a potential association with adverse neurodevelopmental outcomes including later diagnosis for ADHD and autism, prompting the FDA to notify physicians and limit Tylenol use during pregnancy unless medically necessary. The plan calls for spacing vaccines, breaking up shots across four or five visits, and taking mercury and aluminum out of vaccines; delaying hepatitis B to age 12; and separating MMR. The NIH launches the Autism Data Science Initiative with $50,000,000 for 13 projects and exposomics to study root causes and therapies, and Leukavorin for autism treatment.

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Vaccines don't cause autism. The science is clear. Vaccines don't cause autism. Vaccines do not cause autism. I do not deny that we need to do more about autism, but it has nothing to do with vaccines. We have thoroughly debunked any association between autism and these vaccines. Robert, it is nearly consensus in the scientific community that there's no link there. To deny a mountain of scientific evidence, which has already taught us that the combination of measles, mumps, rubella, or MMR vaccine doesn't cause autism, Vimerosal, an ethylmercury containing preservative that wasn't a number of vaccines doesn't cause autism, and that too many vaccines given too soon, if you will, doesn't also cause autism. We know that the schedule is safe. Are there peer reviewed scientific reports that indicate a link between No. Between vaccines and autism? No. Not only is there not a peer reviewed work, this is probably the most studied public health issue involving children. Vaccines are really the one thing we have looked at as causing autism. The Institutes of Medicine, the Centers for Disease Control have repeatedly investigated this. Vaccines do not cause autism. We don't need more research. At some point, enough is enough. It's fine to continue to collect data, but at some point, you have to take note for an answer. We're not sure what causes autism, but we know that vaccines do not. Mountains of evidence. No, you know, this has been looked at extensively. Nothing's been more studied in the world than this connection between vaccines and autism. We'd heard it. We've heard it for decades. You know, actually almost a century now, if you want to get into it. This has been the battle cry of the pharmaceutical industry and every shill that works for them. But whether you know it or not all the way back in 2020 for those of you that were watching then we actually disproved this myth right then. Debunked it with a lawsuit where we went at the CDC and said really if the head of your page on the CDC website says vaccines plural meaning all vaccines do not cause us to do we have that original website. This is what it said: vaccines do not cause autism. There it is. All vaccines doesn't say one of them or two of them all vaccines by the plural s at the end of vaccines. If vaccines do not cause autism will you please provide us with all of the evidence and studies that show that vaccines don't cause autism. Send us that evidence. Well they didn't and we sued them and we went to court. Back in 2020, we won the case. Here it looks like in the document. They gave us the list. It's actually 20 studies. 20 total studies make up the entire list of what they look to when they say that these childhood vaccines, the five, and the cumulative effects of them given in the first six months of life, do not cause autism. The first one is an MMR study. The second one an MMR and a DTaP study. The next ones are MMR, these four are MMR and Thimerosal studies. Then the next all the way through to 20 are all just Thimerosal studies. Lastly, we have one antigen study. Of the 20 studies, the first MMR studies are not in the first six months of life; Thimerosal studies show none of the vaccines in the first six months of life had Thimerosal. There was only one study relevant to the first six months of life, the IOM review of the DTaP vaccine, and it said there are no studies that prove or disprove the association with autism. Therefore, that was the only one that was relevant to the first six months of life, and it proved that they had no answers. And so for everyone that's ever sent Mountain of Evidence, that's been a lie. We won in court. It's a lie. You can take that to the bank. And actually just months after winning that lawsuit, that was in May, by August they pulled down the statement vaccines do not cause autism. We celebrated it but five months later it went back up and we've been stuck there with this propaganda statement that have no basis in science up until last night when this happened to the website. Let's see the new page. Here it is. It now says autism and vaccines and right under that it has the key points. So we read those key points. The claim vaccines do not cause autism is not an evidence-based claim because studies have not ruled out the possibility that infant vaccines cause autism, meaning those vaccines in the first six months of life. Meaning the IOM lawsuit that proved that. Studies supporting a link have been ignored by health authorities. HHS has launched a comprehensive assessment of the causes of autism, including investigations on plausible biologic mechanisms and potential causal links. It does have an explanatory statement I want to read right now. It says this about why you will still see it with an asterisk the header vaccines do not cause autism has not been completely removed due to an agreement with the chair of the U.S. Senate Health, Education, Labor and Pensions Committee that it would remain on the CDC website. Apparently, this was that backroom deal that was made with Senator Cassidy, of course, when Robert Kennedy Jr. was up there. But now you can see on the page it is clear we are making the statement or it's being made by the CDC that this is not a scientific statement and so ultimately this is a massive change. I tweeted out about it today and to every parent of an autistic child that's been out there. For every one of you that did interviews, whether in the film Vaxxed or when we toured the nation and for everyone that's ever been gaslit, the days of gaslighting are over. We are now moving into science-based, evidence-based statements on the CDC website. It's a beautiful day.

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If we're gonna make America healthy again, we can't allow public health to be undermined. So could you explain what steps you're gonna be taking to ensure vaccine guidance is clear, evidence based, and trustworthy? We're going to make it clear evidence based and trustworthy for the first time in history. Only one of those 19 vaccines, 92 doses, only one of those vaccines has ever been tested against an inert placebo. And what we're doing now is any new vaccine that before it's approved and licensed will have to show demonstrate safety against inert placebo. And we're going to go back and do observational studies on the existing vaccines to see if they're linked to any of these chronic disease epidemics so that people can understand the risk profile of those products and make good assessments for their own health.

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I signed an executive order last Thursday to establish the Maha Commission. We'll be studying the reasons behind the decline in American health over the last two generations. We will bring together representatives from all perspectives to investigate the rise in chronic diseases. We will investigate many potential factors, like childhood vaccine schedules, electromagnetic radiation, glyphosate and other pesticides, ultra-processed foods and additives, psychiatric drugs, microplastics, and more. Nothing is off limits. I'm willing to subject all my past beliefs to unbiased scientific scrutiny. We will use unbiased science to guide us, and our goal is to commission research that satisfies all stakeholders. We will agree on protocols in advance and avoid altering study outcomes midway. Let's depoliticize these issues, find common ground, and renew our search for truth without political barriers or preconceptions.

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The speaker states that the NIH has a division devoted to studying long COVID and figuring out cures. They are also incorporating an agency within the CDC that will specialize in vaccine injuries. These issues, along with Lyme disease, are priorities because more and more people are suffering from these injuries. The speaker claims they are committed to having gold standard science to figure out what the treatments are and deliver the best treatments possible.

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Speaker 0: Because there was such a mass vaccination campaign with a product that, you know, tens of thousands, hundreds of thousands of people were injured in this process, what work is the NIH doing in terms of research to somehow help these people? Because just from my own experience, my wife and I made a film about this, right? These people were, even though in some cases they were supported a bit by, but mostly just completely gaslit and just, no, your issue doesn't exist. Right? So how are you approaching this? Speaker 1: Well, you're absolutely right. There were absolutely like, lot patients of who were vaccine injured were gaslit, pretending as if they didn't get injured or that somehow their symptoms are all Speaker 1: in their head or something. Actually, this is part of a broader phenomenon, where, you have patients with conditions that are poorly understood, where the medical system will gaslight them leave. They can they're telling you it's a a psychological issue rather than a physical issue. It should make you think that you're crazy because you you you have symptoms that you just, you know you have, but you can't convince anyone else to do anything about it. Injury is one of them, long COVID, MECFS, Lyme chronic Lyme disease, a whole host of these conditions where it just fits a very similar pattern. Speaker 1: The key underlying thing is that there isn't excellent science to guide decision making for clinicians or anybody else, for patients. And I've made sure that people know at the NIH that I'm very interested in investing in answers for patients for all of those. Vaccine injury, long COVID, MECFS, chronic Lyme. We need to get better answers. The the gaslighting happens because the, if you're let's say you're a doctor and you see a patient and you have no idea what's causing their condition. Speaker 1: Right? Because the scientific literature doesn't have an answer. You're gonna be unless you're an amazing doctor who's really good at, you know, sort of being honest and compassionate, you're going to be wanting to, like, move on to the next patient. And, it's really, really unfortunate. The answer is to get good answers, right? Speaker 1: So invest in, research on treatments, on underlying physiology, physiological causes, you know, basic biological knowledge, so that those patients actually can can the doctors and the caregivers for those patients can will treat them correctly. Speaker 0: So but is is NIH doing this for people that are that have been COVID vaccine injures against a huge number of people relatively. Speaker 1: We have investments in that, and we're going have more investments in that at the start, you know, this year. For all of those conditions, I think patients deserve an answer, and I'm definitely, interested in finding I would love to know myself.

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The speaker says their first break with the Democratic Party was over a Rolling Stone piece about rising autism rates. As secretary, they commissioned a study of autism, because previous CDC studies claimed no link between vaccines and autism. However, the Institute of Medicine stated in 2001 that such a link was biologically plausible and criticized the CDC's vaccine schedule decision-making process, alleging industry capture of the ACIP panel. The speaker claims the CDC only conducted epidemiological studies using fraudulent techniques, instead of a range of studies recommended by the Institute of Medicine. They allege a 1999 CDC study, led by Thomas Verstraten, found an 1135% elevated autism risk in vaccinated children, but the CDC concealed and manipulated the data. The speaker says they will conduct observational, retrospective, and epidemiological studies, making databases public for independent scientists. Grant requests have been issued to the scientific community, with initial answers expected by September, and definitive answers within six months. The speaker expects these answers to differ from the status quo. They advocate for independent research over blindly trusting experts, and promise gold standard science, publishing protocols, peer reviews, raw data, and requiring replication of every study.

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I signed an executive order last Thursday to establish the MAHA commission, which will investigate the decline in American health over the last two generations. We will bring together people with different ideas to study the reasons behind the big increase in chronic diseases. We'll look into things like childhood vaccine schedules, electromagnetic radiation, pesticides like glyphosate, highly processed foods, artificial additives, psychiatric drugs, microplastics, and more. We won't rule anything out. We will use unbiased science as our guide. I want us to do research that will make everyone happy once and for all. We will agree on the study methods ahead of time and not change the results halfway through if they are not what we expect. Let's take the politics out of these problems, find common ground, and look for real truth without political obstacles or biases.

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Research has revealed that folate deficiency in a child's brain can lead to autism. We have also identified an exciting therapy that may benefit larger numbers of children who suffer from autism. Peer reviewed literature has documented that up to sixty percent of folate deficient children with ASD can have improved verbal communications if given Leukavorin. I have instructed NIH, FDA, and CMS to help doctors treat children appropriately. Jay will help tell that story, which started with sound science, the kind that restores faith in government.

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"autism is such a tremendous, horror show what's happening in our country and some other countries, but mostly our country." "We will have announcements as promised in September." "We're finding interventions certain interventions now that are clearly almost certainly causing autism." "In 1970, the biggest epidemiological study in history was done in Wisconsin." "They looked at 900,000 children and they were looking for autism." "incident rate of point seven." "Today, our most recent numbers are one in every thirty one kids." "California, which has the best collection system, is reporting one out of every nineteen children American children as autism, one in every twelve point five boys." "So it's gone from one less than one in ten thousand in 1970 to one in twelve point five boys." "We will."

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Trump has asked me to reorganize the federal health agencies, the agencies that have a portfolio that affects human health, which is CDC, NIH, c d FDA, as well as some of the agencies within the United States Department of Agriculture. He’s asked me to clean up the corruption, number one. He’s asked me to end the conflicts of interest, return those agencies to their rich tradition of gold standard empirically based evidence based science, evidence based medicine, and to end the chronic disease epidemic in this country. And he’s asked me specifically to measurably reduce chronic disease in our children within two years. Okay.

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The speaker believes someone is serious about MAHA and concerned that vaccines cause autism, a claim he previously made but then stopped. Robert Kennedy also believes this and commissioned a study of existing data, specifically US government datasets like CMS, Medicare, and Medicaid. The study aims to detect a connection between the expansion of the vaccine schedule and the rise in autism. While a connection cannot be definitively stated, it seems likely to the speaker, and the president is reportedly concerned about it.

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The speaker envisions a future where the NIH focuses on understanding the causes of American sickness, with 80% of its budget dedicated to innovations that reverse and prevent disease. A more deregulated FDA encourages innovation from therapeutic and preventative device makers, and has been freed from conflicts of interest. The CMS department is working with Medicare, Medicaid, and private insurance to evolve the standard of care towards science, addressing lifestyle conditions that the current medical system doesn't incentivize reversing or preventing. The CDC is improving infectious disease procedures while also focusing on preventing and reversing chronic disease. The speaker claims this paradigm shift, driven by voters, will lead to a healthcare system focused on prevention and reversal, rather than being predicated on more Americans being sick.

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Autism rates are rising, currently estimated at one in thirty-one and one in twelve, a significant increase from one in ten thousand in the speaker's childhood. A large-scale testing and research initiative involving hundreds of scientists worldwide has been launched. By September, the speaker claims they will know the cause of the autism epidemic and be able to eliminate the exposures responsible.

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The speaker states that Trump has asked him to reorganize the federal health agencies whose portfolios affect human health, specifically the CDC, NIH, FDA, and some USDA agencies. The goals are to clean up corruption, end conflicts of interest, and return these agencies to their “rich tradition of gold standard empirically based evidence based science, evidence based medicine.” He adds a aim to end the chronic disease epidemic in the country, with a specific request to measurably reduce chronic disease in children within two years.

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Speaker 0 notes anecdotal data and studies suggesting improvement of Parkinson’s disease with fecal microbiota transplant, mentioning China studies and that Johns Hopkins will start a study on it. They say we’re at the beginning of all this and, in the future, people may look back and see how archaic some early practices were, such as operating on a kidney instead of changing the microbiome. They reference data showing a signature microbiome in anxiety, noting that during COVID people were very anxious, and that this could be related to the media, the disease itself, or treatments. Speaker 1 observes there is open-minded thinking around health, especially preventative medicine, and a strong focus on autism at the moment. They ask for recommendations on approaching autism through the biome or more broadly. Speaker 0 responds that they would love to work with this government and governments worldwide to address autism, which affects every country and its children. They propose that COVID eroded trust in agencies, government, and pharmaceutical companies, and position themselves as someone who could rebuild that trust by driving proper research, focusing on the microbiome, and understanding diseases thoroughly. They advocate for international collaboration among clinicians and researchers, recounting experiences with colleagues in Italy and Germany who were conducting clinical trials. They express a willingness to coordinate with international colleagues to apply successful approaches to patients in the United States. Speaker 0 emphasizes the importance of global collaboration among clinicians to understand and fix autism in children, arguing that with one in twelve and a half boys in California affected, the issue demands attention. They ask, when is the right time to act—if not now, when? They conclude that the only way to fix this is for humanity to come together for the sake of children and future generations.

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Kendall asks for an explanation of the process by which the MMR vaccine causes autism, referencing the movie Vaxxed. Speaker 2 responds that they are currently researching those questions, as parents and physicians have reported children developing autism immediately after the MMR vaccine. The speaker claims studies that should have been done long ago were not. Instead, the speaker alleges that captured researchers at the CDC, mainly people who work for the pharmaceutical industry, produced bad epidemiological studies. The speaker asserts that these studies deliberately avoided comparing health outcomes in vaccinated versus unvaccinated groups. Speaker 0 states that this is one of the things they are studying now with gold standard science. Speaker 2 confirms they are doing gold standard science, which includes replication. They are allocating about 20% of their budget to replicating studies. Speaker 0 explains replication as an independent group repeating a study with the same parameters and data sets to achieve the same result. Speaker 2 agrees.

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"And, you know, we're not here to judge anyone that did take a shot." "And in fact, what we need to focus on now is government funding, NIH funding for those who did and are still suffering." "There are a lot of people left in the wake of this program." "However, I think these bold moves give us basically fodder for the cannon to continue to fire and say, look, we will work on better science, better technology, but let's not forget those who were harmed by this." "And we need to focus on better technologies, not gene therapies that go to every cell in the body, not gene therapies for respiratory viruses." "As the secretary said, look, we're for good science. We're not trying to pull everybody's vaccine away from them, but we're not gonna allow them to take unsafe ones."

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Trump has tasked me with reorganizing federal health agencies like the CDC, NIH, FDA, and some USDA agencies. The goals are to eliminate corruption, resolve conflicts of interest, and restore these agencies to their tradition of evidence-based science and medicine. Additionally, there is a focus on addressing the chronic disease epidemic in the country, with a specific aim to significantly reduce chronic diseases in children within two years.

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Politics should not have anything to do with treating kids with autism, because autism affects Democrats, Republicans, independents, races, religions, sexes. One in twelve and a half boys in California have autism; we must pay attention and put hands on deck. This is a physician-initiated IND (investigational new drug) trial: as a physician, I'll look at each child and ask why it worked in this kid and why it didn't work in that kid, and what I can do for the child it didn’t help. This is frontline clinical trials where physicians try different approaches. I'm focusing on the microbiome and an answer with fecal transplant. But what about the kid without a microbiome abnormality, or with a neurological primary? What about the kid with inflammatory bowel disease with destroyed mucosa that needs fixing before implanting microbes? What about brain-gut connections and genetic problems? These are different ways to treat.

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Trump has asked me to reorganize the federal health agencies—the CDC, NIH, FDA, and some USDA agencies—that have a portfolio affecting human health. He wants me to clean up the corruption, end the conflicts of interest, and return these agencies to their tradition of gold standard empirically based, evidence-based science and evidence-based medicine. He also asked me to end the chronic disease epidemic in this country and, specifically, to measurably reduce chronic disease in our children within two years.

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President Trump asked Speaker 1 to investigate the cause of something. Speaker 1 is approaching the investigation agnostically, looking at everything, and will be transparent in the study designs. The studies will be contracted out to 15 premier research groups from all over the country. They will examine mold, parental age, food and food additives, pesticides, toxic exposures, medicines, and vaccines. Speaker 1 believes they will have preliminary answers in six months, but definitive answers will take about a year after that.

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Autism is a complex disorder with multifactorial ideology. We are continuing to investigate multiplicity of potential causes with no areas of taboo. One area that we are closely examining, as the president mentioned, is vaccines. Some forty to seventy percent of mothers who have children with autism believe that their child was injured by a vaccine. President Trump believes that we should be listening to these mothers instead of gaslighting and marginalize them marginalizing them like prior administrations. Some of our friends like to say that we should believe all women. Some of these same people have been silencing and demonizing these mothers for three decades because research on the potential link between autism and vaccines has been actively suppressed in the past.

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The speaker wants the agency to focus on cures and meaningful treatments, contrasting this with the previous administration's focus on fighting misinformation and DEI. They believe in right to try and state there are amazing new treatments in the pipeline for stage four cancers, neurodegenerative disorders, and diabetes. The speaker questions the lengthy drug approval process and suggests reevaluating the focus on blaming children for illnesses instead of examining the food supply. They question the reliance on willpower when many children suffer from belly pain or attention deficit disorder and are on medication. The speaker advocates for using both common sense and gold standard science, which is the charge from Secretary Kennedy.

a16z Podcast

America's Autism Crisis and How AI Can Fix Science with NIH Director Jay Bhattacharya
Guests: Jay Bhattacharya, Erik Torenberg, Vineeta Agarwala, Jorge Conde
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A bold mission to fix science from the inside out unfolds as NIH director Bhattacharya lays out a Silicon Valley–inspired portfolio. Six months in, he launches a $50 million autism data-science initiative, with 250 teams applying and 13 receiving grants to pursue data-driven answers for families. He cites the CDC’s estimate of autism at 1 in 31 and argues for therapies that actually work and clearer causes to guide prevention. One funded effort centers on folinic acid treatment delivering brain folate, improving outcomes for some children with deficient folate processing, including speech in a subset. Not all benefit, but wider access could help. A second thread urges caution with prenatal acetaminophen use, noting evidence of autism risk and signaling guideline changes. He also highlights a cross-agency push on pre-term birth to narrow the US–Europe gap in prenatal care. The dialogue then shifts to the replication crisis in science, born from volume and conservative peer review. Bhattacharya, a longtime grant-panelist, argues that ideas stall because reviewers cling to familiar methods and fear novelty. He describes NIH reforms modeled on venture capital: centralized grant reviews, empowering institute directors to curate portfolios, and rewarding success at the portfolio level rather than individual wins. He emphasizes funding early-career investigators to bring fresh ideas while evaluating mentorship of the next generation. The aim is a sustainable pipeline that balances risk and reward, mirrors scientific opportunity, and aligns with the institutes’ strategic plans. He calls for a broader, transparent conversation with Congress and the public about funding and progress toward healthier lives. He ties trust to gold-standard science—replication and open communication—and notes how HIV/AIDS-era public pressure redirected NIH priorities. The Silicon Valley analogy endures: a portfolio of bets, most fail, a few breakthroughs transform health. AI can accelerate discovery, streamline radiology, and optimize care, but should augment rather than replace scientists; safeguards must protect privacy while expanding open access and academic freedom. The long-term aim is to reduce chronic disease and improve life expectancy. He closes with Max Perutz’s persistence as a blueprint for patient science. He envisions an NIH that protects academic freedom, expands open publishing, and uses AI to augment, curating a diverse portfolio balanced by evidence and bold bets to lift health outcomes for all Americans.
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