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John Mersheimer argues that the war against Iran is not proceeding as the United States hoped and that there is no plausible off-ramp or decisive pathway to victory. He contends that Washington cannot narrate a decisive end to the conflict the way it could have against Nazi Germany or Imperial Japan, because the war has not produced a decisive Iranian collapse. Instead, Iran has an incentive to convert the fight into a protracted war of attrition and possesses the means to do so, including a broad set of missiles and drones and the ability to retaliate across the region. The result, he says, is a stalemate in which Iran would drive a hard bargain to secure sanctions relief or other concessions, and escalation by the U.S. and Israel will simply provoke Iran to escalate further.
On why Iran will not settle on American terms, Mersheimer emphasizes that Iran has a strong hand and time on its side. He notes that the more time passes, the more desperate the U.S. will be to settle, which strengthens Iran’s position. He argues that even heavy bombardment would not compel Iran to quit; rather, Iran could strike back against Gulf states, Israel, and American assets with significant effect. The Gulf States are particularly vulnerable due to a small number of petroleum sites, short-range missiles, drones, and, crucially, desalination plants that provide most of their fresh water. He cites Saudi Arabia, Kuwait, and Oman as heavily dependent on desalination, implying that destroying such infrastructure would have catastrophic humanitarian and economic consequences. Iran could also target energy infrastructure, and even if the Strait of Hormuz remains open, widespread damage to Gulf energy infrastructure would devastate the regional and global economy. He warns that Israel could suffer increasing Iranian pressure as time goes on, especially as interceptors become depleted.
Regarding energy and the Strait of Hormuz, Mersheimer stresses that 20% of the world’s oil and gas passes through the Persian Gulf, making the energy dimension the war’s most consequential aspect. He argues that opening the Strait of Hormuz would be exceedingly difficult, and destroying desalination and petroleum infrastructure in the Gulf States would negate any advantage of keeping the straits open. He suggests that escalation without a viable endgame will have grave economic repercussions for the world, pushing the U.S. toward a coerced end that would not be a victory.
Mersheimer contends that strategic bombing or air power alone cannot win such wars. He contrasts World War II and Korea/Vietnam with the present, where there are no boots on the ground and no clear path to victory via air power alone. He notes that the deterrent value of air power is limited, and a regime change strategy is notoriously difficult without ground forces. He argues that the decapitation strategy and ongoing escalations are unlikely to produce a decisive American/Israeli victory, and could instead lead to a stalemate or American concession under economic strain.
On leadership and credibility, Mersheimer critiques U.S. leadership, particularly President Trump, for ignoring warning from generals and the National Intelligence Council that regime change was unlikely to succeed. He cites General James Mattis-era warnings that there was no viable military option and notes the pre-war intelligence that suggested limited prospects for quick regime change. He points to Trump’s sometimes contradictory and inaccurate statements about Iranian capabilities, including claims that Iran possessed Tomahawk missiles and that U.S. strikes had erased Iran’s nuclear capability. He argues that such statements undermine U.S. credibility, though he distinguishes between outright lies and genuine mistaken beliefs by leaders.
The discussion also covers Russia’s involvement, with Russia believed to be providing intelligence to Iran and possibly supplying matériel and oil if needed. Mersheimer asserts that the war benefits Russia strategically: it diverts U.S. resources from Europe and Ukraine, potentially worsens Ukraine’s trajectory, and could raise global energy prices that benefit Russian revenue. He suggests that Russia, and possibly China, have strong incentives to aid Iran to counter American power.
Europe’s role is analyzed as largely symbolic or marginal in determining the war’s outcome. Mersheimer argues that European elites are aligned with the U.S., prioritizing NATO continuity and the maintenance of American military presence, despite the damaging consequences for Europe. He suggests a radical approach for Europe: adopt a hardball stance toward the U.S., diversify its economic and strategic relations (including with China, Russia, and India), and resist being economically manipulated or coerced by Washington. He emphasizes that Europe’s interests would be better served by reducing overreliance on the United States and pursuing a more balanced set of strategic partners.
Towards the end, the hosts revisit the idea that leaders lie and that liberal democracies tend to rely more on public persuasion and propaganda, with Trump’s statements illustrating the complexities of truth in international politics. The conversation ends with a reflection on whether Europe should recalibrate its posture toward the United States and broaden its strategic hedges to protect its own interests, rather than assuming continued U.S. leadership in a costly and protracted confrontation with Iran.