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One of the main health harms from alcohol, especially heavy alcohol use, is liver damage. The first thing that happens is inflammation of the liver. And when your liver gets inflamed, you start getting fat deposit in the liver. That actually can totally reverse if you stop drinking or you make changes. The amazing thing with the liver. It's a really regenerative organ. But there is a point where you cross the threshold where you can no longer repair the damage, and that's when you get to a stage called cirrhosis. From fat deposition, then you start getting scarring. Your body lays down all the scar tissue because of the chronic inflammation in your liver and when your liver becomes so scarred that it's really stiff and and starts not functioning well that's cirrhosis. I'm seeing people in their early 30s with cirrhosis in the hospital. What? Yes.

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Main offender is alcohol. I know that's not the offender in you. But the main offender for liver inflammation is alcohol because it's not the alcohol itself. It's what the alcohol becomes. Alcohol is converted into something called acetaldehyde, which makes your blood pH very low, very acidic, and this irritates the the liver. But don't forget the liver's filtering out everything. The liver is like if you want any organ on team Ryan, you want the liver. Right? It can take over the function of other organs. Main offender is alcohol. I know that's not the offender in you.

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Fatty liver disease is the accumulation of fat in and around the liver. It can arise from two factors: alcoholic fatty liver, with increased alcohol consumption, and nonalcoholic fatty liver, for which hypothyroidism can be a major contributor. Hypothyroidism raises TSH, slows metabolism, and promotes fat storage. High TSH can also increase insulin resistance, leaving more glucose in the blood, which the liver converts to glycogen—adding more fat. Increased TSH also raises triglycerides and LDL cholesterol, harming the liver. A poorly functioning liver impairs conversion of thyroid hormone T4 to T3, worsening hypothyroid problems. If liver doesn’t break down cholesterol, LDL and triglycerides rise, increasing cardiovascular risk. NAFLD often has few symptoms; AST and ALT can be elevated, prompting ultrasound for diagnosis. If this information’s helped, please like, share, and follow.

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Those with IBD or other gut issues likely also have liver issues. IBD and IBS almost certainly involve dysbiosis, an imbalance of gut bacteria that worsens symptoms like bloating, gas, and inflammation. As these bacteria die off, the body tries to excrete them. Due to leaky gut, blood vessels lead to the liver. Inflammation and dysbiosis cause endotoxins to be flushed through the liver, potentially damaging it and affecting detoxification, bioproduction, mood, and energy. An overwhelmed liver can lead to systemic issues like brain fog, headaches, hair loss, and eczema. Therefore, if you have SIBO, IBS, or IBD, you most likely have liver issues.

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We often think about sleep in terms of energy and productivity, but you might be surprised to learn that it also plays a critical role in maintaining liver health. Research shows that consistently getting less than eight hours of sleep per night is associated with a higher risk of developing liver disease. For individuals who already have liver disease, poor sleep can make their symptoms worse, leading to worsen fatigue, cognitive impairment, and overall reduced quality of life. The liver and your sleep quantity and quality are definitely connected. Liver disease negatively affects sleep through multiple mechanisms. First, reduced liver health disrupts your body's natural melatonin levels. Melatonin is an essential hormone that regulates our sleep and wake cycles. So when melatonin is dysregulated, it can lead to sleep disturbances. On the other hand, chronic sleep deprivation can worsen liver disease itself. Poor sleep has been linked to insulin resistance, increased inflammation, and metabolic dysfunction, all of which can contribute to liver fat accumulation, fibrosis progression, and as damage accumulates over the long term, cirrhosis.

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Transcript emphasizes that the liver, not the digestive tract, should be the first check for digestive issues: 'The number one place is not to look to your digestive tract' and 'The very first place that we need to look is actually your liver.' It explains that 'Your gallbladder, if you still have one, is attached to your liver' and that 'Your liver makes something called bile and then that bile gets excreted or pumped out into your small intestine' after food leaves the stomach. It notes the liver's central role, citing 'I have called the liver the most overworked, underpaid organ in the entire body for many many years.' It lists indicators to look at: 'ALT, AST, bilirubin, alkaline phosphatase, albumin' and mentions liver-active hours 'between two and 4AM.' It ends with 'For more info, click the link below.'

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Lack of oxygen is linked to chronic fatigue syndrome, and increasing oxygen levels is key. Dehydration can be a contributing factor. While counterintuitive, exercise can help improve energy levels. Mold exposure can also lead to insufficient oxygen intake, causing cells to operate at low energy levels. Identifying the root cause requires investigation. The presence of animals in the home can also affect chronic fatigue syndrome.

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"Often overlooked root cause of chronic low energy levels and fatigue is an overburdened sluggish liver." "Two of the main things that our livers get overburdened with are viruses and heavy metals." "If our livers reach this point where they it can't detox all of these toxins, it's going to start spilling out into our system." "The viruses create viral byproducts." "These byproducts spill out of our liver and goes into our system." "It causes our brain to become very inflamed." "The inflammation can affect our adrenal glands." "It's really important when we're dealing with chronic fatigue, low energy levels, that yes, there could be other contributing factors going on, but we will really be amiss if we are not looking at the liver and potentially figuring out why our liver is overburdened and start a path of cleansing and getting it rejuvenated again."

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Heavy metals can be an underlying root cause of autoimmune issues, migraines, psoriasis, and skin conditions. Consuming heavy metals causes damage to the gut microbiome, leading to poor absorption of vitamins and minerals, resulting in deficiencies and toxicities as metals enter the bloodstream. Healing involves addressing deficiencies and lowering toxicities by removing heavy metals and rebalancing the gut microbiome. While detoxing, it's important to limit new heavy metal intake by using water and shower filters, eating low-mercury fish, and choosing low-arsenic rice. Switching out cookware over time can also help. Resources for recommended products are available at stevenkabrall.com/resources. This is how the healing process begins.

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Probiotic foods. I just mentioned this. The friendly flora greatly supports the liver. If you were exposed to an antibiotic or something to destroy your good flora, the liver suffers. If you're exposed to something like aspartame or some other synthetic artificial sweetener, that alters the gut microbiome, which then raises liver enzymes and puts you at risk for a fatty liver. Probiotic foods. I just mentioned this. The friendly flora greatly supports the liver. If you were exposed to an antibiotic or something to destroy your good flora, the liver suffers. If you're exposed to something like aspartame or some other synthetic artificial sweetener, that alters the gut microbiome, which then raises liver enzymes and puts you at risk for a fatty liver.

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Excess calories, especially from refined sugars, processed grains, and seed oils, cause fat buildup in the liver. High fructose corn syrup goes directly to the liver and converts to fat. When the liver is overwhelmed, it stores the excess calories as fat, leading to fatty liver. The stored fat causes oxidative stress and inflammation, damaging the liver. The immune system responds by laying down scar tissue, called fibrosis. Continued fibrosis leads to cirrhosis, a hardened, damaged liver that cannot function properly. Overworked liver cells are more likely to mutate, increasing the risk of cancer. Fatty liver is a chain reaction of damage that can be deadly if ignored.

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We're breathing. So if you live in a city, right, for New York, you're breathing all kinds of toxins in all the time. That's hitting the liver. A lot of people that don't think about is they're getting toxicity through, like, topical things, like maybe deodorants. They're getting nanoparticles of zinc that you're putting right into the lymphatic system in the armpit. BPAs, chemicals that could be in shampoos, could be in soap, maybe the water. If you're taking a bath in a city that recycles water, the chlorine level is so high in that water that it even they tell you don't put it in aquarium. You'll kill the fish. But if you're sitting in a bath of that and absorbing all those chlorine, all those toxins, those hormones, so that's another way.

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Belly fat usually occurs after the liver is fatty because a lot of the visceral fat that's around the organs is occurring because there's a spillover from your liver. So if you have belly fat, like you're looking down right now and you can't see your feet, that means your liver has a lot of fat in it. And now it's spilling over into other areas around the body because there's only so much space in the liver. So knowing that information, the top foods that will help you with that have to address either lowering insulin, lowering cortisol, or helping you with a fatty liver.

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itchiness, especially in your feet fatigue or lethargy belly fat because the liver is filling up with fat and it's spilling off into areas around the organs and in the organs in your abdomen Diabetes and prediabetes and insulin resistance, which comes before both of those things. Hormonal imbalances, especially with estrogen, testosterone, which have all sorts of cascade issues from hair loss to menstrual cycle issues to menopausal problems. Many different types of skin problems occur because of the liver. Joint issues, like especially arthritis, stiffness, and the things related to the gallbladder, like belching, burping, bloating, gallstones, as well as hypothyroidism, because we need a healthy liver to convert at least 80% of the thyroid from T4, the inactive, to T3, the active form of the thyroid hormone.

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Excess calories, especially from refined sugars, processed grains, and seed oils, cause fat buildup in the liver. High fructose corn syrup goes directly to the liver and converts to fat. When the liver is overwhelmed, it stores the excess calories as fat, leading to fatty liver. Over time, this stored fat causes oxidative stress and inflammation, damaging the liver. The immune system responds by laying down scar tissue, called fibrosis. Continued fibrosis leads to cirrhosis, a hard, damaged liver that cannot function properly. Overworked liver cells are more likely to mutate, increasing the risk of cancer. Fatty liver initiates a chain reaction of damage that can be deadly if ignored.

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Fatty liver disease impacts immediate health, not just long-term risks. A fatty liver fuels inflammation and disrupts metabolism, worsening insulin resistance and potentially leading to prediabetes and type 2 diabetes. Symptoms include fatigue, post-meal sluggishness, sugar cravings, mid-day energy crashes, and brain fog. It promotes belly fat storage and hinders fat loss, while also increasing chronic inflammation, damaging blood vessels, and raising blood pressure. The condition also disrupts cholesterol processing, elevating dangerous triglycerides. Fatty liver is a metabolic roadblock that can make you feel worse, burn less fat, and age faster. Early action makes reversal easier.

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The speaker claims a benefit of something is the ability for the liver to detoxify better. They also state it will cause a release of bile, which will help in digesting fats. The speaker says this will help the liver work and help the digestive juices work through that area.

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If you're waking between 1AM and 3AM, your liver might need extra support. Research shows that detoxification has a huge link to our circadian rhythm. This means that waking up in the middle of the night could be linked to your liver. The liver is the key organ for detoxification. The liver naturally does most of its detoxification when you're in your deep non REM sleep, around 12AM to 3AM. It processes and metabolises cholesterol, fatty acids, glucose, thyroid hormones, bile acids, iron, and everything in between. So if your liver is congested or imbalanced, this can affect your wake sleep cycle, your sleep rhythm. Does this sound like it relates to you? Do you think that your liver could be playing a role in the way you sleep or in the way your sleep is being disturbed?

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Leaky gut allows undigested food particles to seep into the bloodstream, overwhelming the immune system and potentially leading to chronic fatigue and other health problems. The speaker claims there is an easy solution to this problem.

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Fatty liver disease impacts immediate health, not just long-term risks. It fuels inflammation and disrupts metabolism, worsening insulin resistance and potentially leading to prediabetes and type 2 diabetes. Symptoms include fatigue, post-meal sluggishness, sugar cravings, mid-day energy crashes, brain fog, and increased belly fat. A fatty liver gums up the metabolic engine and increases chronic inflammation, keeping the immune system in fight mode. This damages blood vessels, increases blood pressure, and disrupts cholesterol processing, raising triglycerides. Fatty liver is a metabolic roadblock that makes you feel worse, burn less fat, and age faster, and early action is key to reversing it.

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Are you having digestive issues? The number one place is not to look to your digestive tract. The liver has a profound digestive component to it. The gallbladder, if you still have one, is attached to your liver. Your liver makes something called bile and then that bile gets excreted or pumped out into your small intestine after your food leaves your stomach. If the liver is sluggish, digestion is the first task that it throws out the back door. The liver enzymes to look at: ALT, AST, bilirubin, alkaline phosphatase, albumin. Not sleeping well between two and 4AM is described as a liver active time. For more info, click the link below.

Genius Life

Why You Feel So Tired All The Time! (Do THIS To Have More Energy!) - Dr Rupy Aujla

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Fatigue is more than a mood—it's a signal from your body. The guest, Dr. Rupy Aujla, outlines how a misaligned circadian rhythm underpins tiredness for millions, with light as the master regulator of the brain’s SCN clock. Morning light triggers a cascade that wakes the digestive system, liver, and pancreas; sunset signals winding down. Travel, plane jet lag, and night shifts exacerbate the disruption, often leaving people inflamed and unsteady. He notes that circadian misalignment is a weekly, not just occasional, stress, shaping energy levels and immune activity. Coupled with misalignment is a persistent low-grade inflammatory milieu. Inflammation is the language of the immune system, but chronic “meta-inflammation” from poor sleep, lack of fiber, loneliness, and processed foods can drive fatigue and later disease. The episode cites 30 million Americans with sleep apnea, but only about 6 million formally diagnosed, highlighting underdiagnosis as a key fatigue driver. Caffeine appears as a double-edged aid: it blocks adenosine receptors, delaying the inevitable crash, with a half-life of 8 to 10 hours and variation by metabolism. To counter fatigue, the guest recommends practical circadian strategies: wake up at the same time daily, get outside for bright morning light, and have an early dinner two to three hours before bedtime to preserve melatonin. He emphasizes a cooler, darker sleeping environment and acknowledges air quality as a hidden factor, citing high indoor CO2 levels that can wake the brain. A portable sleep mask helps achieve darkness while allowing natural light on awakening. Hydration and mindful caffeine timing further support steady energy. Nutrition and hydration emerge as foundational. The clinician advocates testing iron, vitamin D, and B12, given menstrual status, vegan diets, and gut absorption; vitamin D should be above 50 in many cases, and magnesium, from nuts, seeds, and leafy greens, supports energy. He urges protein and fiber at breakfast to blunt glucose spikes and cravings, with options like eggs, turkey, beans, or yogurt-based snacks. Electrolyte balance matters when exercising or living in hot rooms, and water intake should be tracked by urine color. Finally, regular movement—preferably hourly—boosts mitochondrial biogenesis, catecholamines, dopamine, and glucose transport, reducing fatigue.

Genius Life

WHY YOU'RE ALWAYS TIRED! - Root Cause of Thyroid Dysfunction & How To TREAT IT | Dr. Izabella Wentz

Guests: Dr. Izabella Wentz

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Dr. Izabella Wentz discusses adrenal dysfunction, often referred to as adrenal fatigue, which arises from chronic stress and manifests as symptoms like fatigue, brain fog, and mood swings. While conventional medicine may not recognize adrenal fatigue as a diagnosis, Wentz explains it as HPA axis dysfunction, where the body fails to produce stress hormones correctly. She emphasizes the importance of recognizing and addressing stressors, including toxic relationships and inflammatory foods like gluten, dairy, and soy, which can trigger stress signals in the body. Wentz highlights the significance of cortisol, noting that it should peak in the morning and decline throughout the day. A disrupted cortisol pattern can lead to insomnia and fatigue. She advocates for dietary changes, including a paleo-like diet rich in protein and healthy fats, to restore adrenal balance. Wentz also recommends testing for adrenal function and thyroid antibodies, particularly for those experiencing unexplained symptoms. She shares her personal journey with Hashimoto's thyroiditis and emphasizes the need for awareness and early intervention in autoimmune conditions. Wentz encourages individuals to adopt self-care practices, including proper nutrition and stress management, to promote healing and resilience in the face of modern life's challenges.

TED

A cleanse won't detox your body -- but here's what will | Body Stuff with Dr. Jen Gunter | TED

Guests: Jen Gunter

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Many people ask if they should do a cleanse, but detoxes won't remove toxins from the body. Cleanses, like detox teas and lemon drinks, are marketed based on a misunderstanding of liver function. The liver processes nutrients and waste but isn't "cleaned" by these drinks. Instead, maintaining a healthy liver involves not smoking, eating a balanced diet, exercising, and avoiding excessive alcohol. It's also important to read medication labels and be cautious with supplements, as they can cause liver injury. The best self-care is understanding our bodies to make informed health decisions.

The Ultimate Human

Debunking Health Myths with Sage Workinger-Brecka & Gary Brecka | TUH #199

Guests: Sage Workinger-Brecka

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In this episode of the Ultimate Human Podcast, Gary Brecka and his wife, Sage, address frequently asked questions about relationships, health, and business. They emphasize the importance of scheduling quality time together, suggesting activities like hiking in Colorado where they can disconnect from technology and focus on each other. They've shifted their vacation style to prioritize connection over entertainment, finding that the absence of distractions allows them to enjoy each other's company more. They also highlight the significance of laughter and shared activities like sauna sessions and outdoor adventures for both their relationship and health. The discussion covers various health-related topics, including identifying the root causes of fatigue. Gary recommends starting with a basic blood panel and genetic test to identify nutrient deficiencies or hormonal imbalances. He advises testing for mold, mycotoxins, heavy metals, parasites, and viruses, especially if fatigue is a recent onset. Sage shares her experience with mold poisoning from hurricane damage, emphasizing the importance of testing and detoxification. They also discuss daily habits that can negatively impact energy, focus, and mood, such as focusing on the negative and poor sleep habits. Gary stresses the importance of having a consistent morning routine, including sunlight exposure, breath work, and a mineral-rich drink, to align with circadian rhythms. The couple delves into specific health myths and misconceptions, particularly regarding dieting and intermittent fasting. Sage cautions against restrictive diets, especially for young girls, and advocates for eating whole foods in moderation. Gary debunks the myth that women shouldn't weight train and warns against intermittent fasting for women with low blood sugar, as it can disrupt hormone balance. They also discuss tracking biomarkers, with Gary prioritizing sleep, hormones, and nutrient deficiencies, while Sage emphasizes the importance of tracking steps to encourage physical activity. They explore strategies for increasing mitochondrial function naturally, such as high-intensity cardio and red light therapy, and the importance of detoxifying from mold and heavy metals. The podcast also addresses supplements for children, recommending methylated multivitamins and avoiding fortified foods with folic acid. They discuss supporting young boys with ADHD symptoms through methylated vitamins, folic acid avoidance, and structured physical activity. For those looking to transition off caffeine, they suggest alternatives like cacao and matcha tea, along with a morning cocktail of sea salt, amino acids, and hydrogen tablets. They also offer advice on overcoming itchy skin with supplements like resveratrol and magnesium, and warm showers. The episode concludes with a discussion on weight training in a fasted state, with Gary recommending amino acids before workouts, and strategies for fixing low testosterone without TRT, including lifestyle changes and supplements like boron and DHEA.