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Good and bad bacteria are revived by different things. Changing the pH can wake up good bacteria or put them to sleep. Good bacteria thrive in an acid environment, which protects them because many pathogens cannot live in that acidic environment.

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Microbes have a mutual arrangement with us: we provide a home, and they offer immune protection, vitamins, and digestive help. If the environment isn't good, microbes will become dormant until conditions improve. Lowering the pH, making the environment more acidic, can activate microbes.

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Prebiotics aren't limited to fiber; resistant starches and polyphenols also function as prebiotics. When you eat, the majority of the food is digested and absorbed in the small intestine. However, prebiotics like fiber, resistant starches, and polyphenols remain intact as they enter the colon. These prebiotics uniquely impact the microbiome, supporting beneficial gut bacteria and promoting health benefits.

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Butyrate must be in the colon to nourish colon cells. One approach is taking butyrate-producing bacterial capsules. Another is consuming butyrate precursors through fermented foods and vinegars. Soluble fiber, not insoluble, is also necessary. Inulin, a soluble fiber, can be found in chicory family vegetables like radicchio, Belgian endive, and chicory, as well as asparagus and artichokes. Okra and root vegetables, such as yams and sweet potatoes, are also good sources of soluble fiber.

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The gut microbes affect our brain. Essentially, the gut microbes have our brain on speed dial, and they help coordinate our body's functions. This system is known as the gut brain axis. The two way communication between our central nervous system and enteric nervous system, the nervous system linked to the gut, allows our gastrointestinal tract and brain to talk to each other. This back and forth conversation helps our body maintain physiological balance, also known as homeostasis. The gut microbes even release certain molecules and hormones that can affect our brain. Gut bacteria feed on the food we eat and produce metabolites like serotonin. This serotonin is released into our blood, where eventually it interacts with our nervous system. Some other metabolites include GABA, a neurotransmitter, and butyrate, which interacts in other critical ways with the nervous system.

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The gut, or gastrointestinal tract, is a long tube from mouth to anus responsible for breaking down food, absorbing nutrients, and eliminating waste. It also hosts trillions of microorganisms, collectively known as the gut microbiome, including bacteria, fungi, and viruses. These microorganisms aid in breaking down food into nutrients the body needs.

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Bloating is a sensation of a balloon in the gut, different from distension, which is a "food baby." A little bloating after a high-fiber meal is normal and a sign of healthy gut bacteria. Fiber, found in plant-based foods, is important because human cells can't break it down. It travels undigested to the large intestine, where it acts as fertilizer for the gut microbiome. This explains why fiber is linked to longevity and well-being, as it nourishes the microbiome, which performs beneficial functions.

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Probiotics are different types of bacteria. Prebiotics act as fertilizer for these bacteria. If you think of your gut as a garden, the probiotic is like the seed. The prebiotic then fertilizes the seed, allowing healthy bacteria to grow.

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Health problems arise when bacteria breach the immune wall, enter the bloodstream, and cause systemic infections. Microbes primarily enter the blood through the colon and gums; arterial plaque sometimes contains oral bacteria. Skin problems can stem from translocated gut bacteria. Certain microbes produce butyrate, which affects insulin resistance, and these microbes thrive in acidic environments. Maintaining an acidic pH can increase their numbers, emphasizing the importance of the body's internal environment.

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Butter is a health food full of nutrients beneficial for humans. A recent study showed that patients with irritable bowel syndrome (IBS) were given 300 milligrams of butyrate a day. Butyric acid is found in butter. Over twelve weeks, their IBS symptoms went down significantly. One tablespoon of butter contains 300 milligrams of butyrate. Therefore, one tablespoon of butter a day could significantly improve your gut health, whether you have IBS or not.

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So your body actually recycles bile because it is vitally necessary and important. In fact, it recycles it six to 10 times every single day. And on top of that, your liver makes bile. It's called primary bile salts and your microbiome makes bile. It's called secondary bile salts. Also, bile helps prevent SIBO small intestinal bacterial overgrowth. It competes for nutrients. There'll be less nutrients going into your small intestine because the microbes need them to survive. You're going to be deficient in nutrients. You're going to have a lot of gas, bloating, overgrowth of other pathogens, unfriendly bacteria. So bile salts have antimicrobial properties. So if you eat, especially like fiber or probiotics and you bloat, then chances are you can have SIBO.

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The most important, overlooked aspect of the gut is its speed, not its contents. The 30-foot human intestinal tract functions like Henry Ford's assembly line, a conveyor belt where pH levels dictate the breakdown of contents. Increasing the gut's speed disrupts this process. Acidic bacteria handle contents leaving the stomach, while basic bacteria handle contents near the rectum. Speeding up the gut pushes acidic contents into a basic environment, causing functional problems. This leads to gas, bloating, diarrhea, constipation, irritability, and cramping, which do not originate from food intake.

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Apple cider vinegar acts as a prebiotic for good gut bacteria and kills pathogens like Candida, which causes sugar cravings. It can also kill E. Coli, which may cause bloating or cravings. A tablespoon of apple cider vinegar in water during a fasting window can accelerate microbiome changes. This may benefit those with SIBO, constipation, or diarrhea, and help with weight loss. Apple cider vinegar can shift the microbial makeup of the gut to enhance the benefits of fasting.

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Good bacteria can be activated or deactivated by altering the pH level. Beneficial bacteria flourish in acidic conditions, which also serves as a defense because many pathogens cannot survive in such an environment. Consuming apple cider vinegar acidifies the internal environment.

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Avocado and sourdough bread may help reduce the need for multiple pills. Avocados contain 14 grams of fiber, which fuels bacteria that create small chain fatty acids. These fatty acids fuel the colon cell wall, leading to less inflammation. Two avocados a day provide all the necessary folate, vitamin C, vitamin B6, and potassium, along with the required fiber.

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In the small intestine, most nutrients are absorbed, leaving only fiber. Vitamin B12 is absorbed in the ileocecal valve. Low B12 levels can be caused by a compromised gut or lack of intrinsic factor release. The appendix plays a role in lubricating and releasing antibacterial fluid to handle toxic substances from the small intestine. The large intestine takes water out to form stools. Chewing too fast and not properly breaking down protein can lead to partially digested protein in the large intestine, requiring the colon to create bacteria to calm it down. A refined diet lacking fiber can cause blockages in the colon. Squatting while using the bathroom can help relax the puborectalis muscle and make elimination easier. Using a Squatty Potty can also aid in preventing colon problems.

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The rapid increase in autoimmune conditions and allergies is unlikely due to human genetics, which change over long periods. People with these conditions often have dysbiosis, a dysregulation of gut health characterized by reduced diversity, fewer healthful microbes, and more pathogenic microbes. While a causal relationship hasn't been established for all autoimmune conditions, mechanisms exist. Dysbiosis leads to a breakdown of the mucosal layer and separation of endothelial cells, which are held together by tight junctions. Butyrate, a short-chain fatty acid, helps maintain these tight junctions. The breakdown allows molecules, like bacterial endotoxins, to flow from the gut into the bloodstream, revving up the immune system. Increased inflammation leads to oxidative stress, causing DNA damage and accelerating tissue aging.

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Fiber is essential for optimal health and gut function. The gut contains 100 trillion bacteria, some good and some bad. Consuming both soluble and insoluble fiber feeds the good bacteria, allowing them to thrive. Without fiber, bacteria will consume the intestinal lining, leading to microscopic leaks in the gut wall, allowing unwanted chemicals to enter the bloodstream and cause inflammation. Insoluble fiber also helps to reduce the risk of colon cancer by brushing away dead cells in the colon.

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Intermittent fasting can affect gut microbes in several ways. When bacteria are put on a fast in mice, fruit flies, or other organisms, they live longer and show increased resistance to oxidative stress and xenobiotic stress (exposure to chemicals such as in chemotherapy). Fasting also increases microbial diversity and the microbes’ tolerance to harmful bacteria, and it can restore the intestinal epithelium, i.e., the lining of the colon. Additionally, fasting starves sugars for yeast and Candida, reducing pathogenic microbes and supporting the growth of beneficial populations. These microbes contribute to the body by recycling and increasing bile acids, which help digest fats. Overall, fasting appears to enhance microbe longevity, diversity, and resilience, while supporting gut lining health and fat digestion through bile acid production.

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Speaker 0: And the really big piece here is that butyrate is generally made by the bacteria that live in your large bowel, the butyrate producers, and it's a short chain fatty acid, right? And is the number one fuel source for the cells that line the large bowel, the colonocytes. It keeps the pH nice and acidic, which is very healthy. A good healthy large bowel is quite acidic and the less friendly bacteria don't thrive in an acidic environment.

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Eating yogurt or taking probiotics is not an effective way to recolonize the gut because they often get killed in the stomach or small bowel and don't reach the colon. Fecal transplants are different because they involve cleaning the colon, looking at the mucosa, and implanting directly. While some people may get lucky with probiotics landing and implanting, most of the time they don't engraft, meaning they don't implant, so you have to keep taking them to sustain any benefit. It's a difficult process and hard to heal the gut that way.

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In some countries in Africa, they're eating 100 grams of fiber every day. When you eat that amount of fiber, is not only gonna make you full, but it's gonna make your gut very healthy because fiber is the food for the good bacteria in our guts. The more fiber you put in your diet, the more you feed the good bacteria in your gut. The better the good bacteria in your gut or the more that's present, the healthier you're going to be.

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Lower fiber diets starve gut bacteria, leading to decreased diversity and potentially causing bacteria to feed on the mucus lining. Studies show fruits, vegetables, tea, coffee, red wine, and dark chocolate correlate with increased bacterial diversity due to their polyphenol content. Conversely, foods high in dairy fat and sugar-sweetened sodas correlate with decreased diversity. Minimally processed, fresh foods with more fiber are better fuel for gut bacteria. Lightly steamed, sauteed, or raw vegetables are typically more beneficial than fried dishes.

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Prebiotics feed microbes and are essential. Fiber, psyllium, fruits, and vegetables are good prebiotics. One should aim for 25-30 grams of fiber daily. As people age, increasing fiber intake becomes more important due to sluggish colons. While beans and lentils are generally considered good sources of fiber, they can cause gas and bloating, especially in individuals with dysbiosis. It's recommended to avoid beans, corn, and chickpeas in these cases. Prebiotic supplements can increase bifidobacteria. Fennel, beets, and sweet potatoes are good prebiotic options. Orange beets are preferred over red beets because red beets can change the color of urine and stools.

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Apple cider vinegar changes your microbiome of your gut because we have good bacteria and we have bad bacteria in our gut. And apple cider vinegar, it is a prebiotic for these good bacteria. But the other thing it does that's really cool is that it'll kill pathogens. We also know that apple cider vinegar can kill things like E. Coli, bacteria in the gut that might be causing you things like bloating or might be causing you to have craved other foods that you are trying to stay away from. Just a tablespoon of apple cider vinegar in your fasting window when you're already changing your microbiome through fasting can really accelerate your microbiome state.
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