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When COVID-19 vaccines were sequenced, commercial annotation software highlighted functional parts of the plasmids, including antibiotic resistance genes and SV40 components. The speaker claims that Pfizer had to manually remove these annotations before submitting the plasmid map to regulators.
According to the speaker, regulators received the DNA sequence, but the sponsor is obligated to annotate every open reading frame and promoter, even if their function is unknown. The speaker alleges that Pfizer intentionally removed annotations, hiding them from the FDA, which the speaker believes is a violation of guidelines.
The speaker suggests the reason for hiding SV40 components is due to SV40 virus contamination in polio vaccines and its debated link to cancer. The speaker asserts that while epidemiological data is confounded by vaccine shedding, laboratory studies show SV40 is a potent oncogenic virus. The speaker claims that the vaccines contain some of the more carcinogenic components of that virus, and that these sequences are functional and have consequences.