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Walking barefoot, or grounding, can prevent inflammation and nail fungus. Nail fungus suggests inflammation, lack of grounding, and parasites. Nail fungus is often linked to poor vision because toes and eyes are connected through energy pathways called nadis.

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Poor gut health symptoms include low energy and skin issues, which are often fungal-related and linked to the gut microbiome. The gut contains good and bad bacteria, with an ideal balance of about 15% bad bacteria. However, herbicides, pesticides, processed foods, and gluten can kill good bacteria, leading to an overgrowth of bad bacteria. If the liver, kidneys, and colon can't process the excess bad bacteria, it manifests through the skin. The skin reflects the health of the gut, mirroring what is consumed. Therefore, one can assess gut health by observing the skin and bowel movements.

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Number one, do you have an intolerance to digesting fat? When you eat fat, do you find that you get more bloating? That would be an indication that you need more bile. Do you find that your stool is light colored, like pale or even gray? Or does it float? Or does it leave skid marks? That could mean that you're low in bile. Do you find that after you eat, you're just not satisfied? Well, maybe because you're not extracting the fats to be absorbed to then tell the brain like, okay, I'm done eating. That could be a sign that you need more bile. If you have nausea or you have indigestion or bloating, those can be signs. Bloating, burping, belching are classic signs of low bile as well.

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Those with IBD or other gut issues likely also have liver issues. IBD and IBS almost certainly involve dysbiosis, an imbalance of gut bacteria that worsens symptoms like bloating, gas, and inflammation. As these bacteria die off, the body tries to excrete them. Due to leaky gut, blood vessels lead to the liver. Inflammation and dysbiosis cause endotoxins to be flushed through the liver, potentially damaging it and affecting detoxification, bioproduction, mood, and energy. An overwhelmed liver can lead to systemic issues like brain fog, headaches, hair loss, and eczema. Therefore, if you have SIBO, IBS, or IBD, you most likely have liver issues.

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We often think about sleep in terms of energy and productivity, but you might be surprised to learn that it also plays a critical role in maintaining liver health. Research shows that consistently getting less than eight hours of sleep per night is associated with a higher risk of developing liver disease. For individuals who already have liver disease, poor sleep can make their symptoms worse, leading to worsen fatigue, cognitive impairment, and overall reduced quality of life. The liver and your sleep quantity and quality are definitely connected. Liver disease negatively affects sleep through multiple mechanisms. First, reduced liver health disrupts your body's natural melatonin levels. Melatonin is an essential hormone that regulates our sleep and wake cycles. So when melatonin is dysregulated, it can lead to sleep disturbances. On the other hand, chronic sleep deprivation can worsen liver disease itself. Poor sleep has been linked to insulin resistance, increased inflammation, and metabolic dysfunction, all of which can contribute to liver fat accumulation, fibrosis progression, and as damage accumulates over the long term, cirrhosis.

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Transcript emphasizes that the liver, not the digestive tract, should be the first check for digestive issues: 'The number one place is not to look to your digestive tract' and 'The very first place that we need to look is actually your liver.' It explains that 'Your gallbladder, if you still have one, is attached to your liver' and that 'Your liver makes something called bile and then that bile gets excreted or pumped out into your small intestine' after food leaves the stomach. It notes the liver's central role, citing 'I have called the liver the most overworked, underpaid organ in the entire body for many many years.' It lists indicators to look at: 'ALT, AST, bilirubin, alkaline phosphatase, albumin' and mentions liver-active hours 'between two and 4AM.' It ends with 'For more info, click the link below.'

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Speaker: The discussion attributes shingles to a lack of collagen. According to this view, your body's collagen is deficient, and you need to repair it. Suggested approaches include dragon's blood, raw butter, raw cream, or raw eggs as beneficial. The explanation frames shingles as open wounds, comparable to chicken pox, herpes, and cold sores—situations where the body is either erupting toxins or attempting to repair but cannot repair fast enough. The speaker notes that different conditions are given different names, which can be confusing, but all are described as the same underlying issue. A simplification offered is to think in terms of missing fats or other nutrients—the idea being that once you recognize you’re missing certain components, the understanding becomes easier. The overall message is that shingles reflects a broader pattern of the body lacking resources (notably collagen and related fats) and needing to repair, with the same fundamental process described across conditions under different labels.

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Osteomalacia involves bones becoming very soft, possibly occurring on a massive scale subclinically. The speaker believes they had it in high school due to poor diet and vitamin D deficiency, leading to fractures. In osteomalacia, certain proteins don't develop well. Vitamin D controls calcium absorption by 20 times in the small intestine. There are two vitamin D systems: one controlling calcium and another that is non-calcium related. A vitamin D blood test will likely show a level of 30 or less, indicating the need to take vitamin D3.

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Yellow eyes, that is a jaundice situation. It's a liver problem. It could be a gallbladder problem where the byproducts of your red blood cells are backing up through the system, through the liver, and into the blood. And so if your skin or your whites of your eyes are yellow, that is definitely a backup of the liver and the gallbladder. And that is usually a deficiency of bile salts. Bile salts allow the flow of stuff through the liver and through the bile ducts. And if you don't have enough bile, this thickened cholesterol sludge tends to back up and you develop these white eyes. So a simple remedy would be to take some purified bile salts to open up this kind of clogged drain plug to allow the body to eliminate the byproduct of red blood cells.

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Nutritional status impacts overall health, and hair loss can indicate poor nutrition. Vitamin A helps the scalp produce sebum, moisturizing hair. B complex vitamins create red blood cells, carrying oxygen and nutrients to hair follicles. Biotin, a B complex vitamin, prevents dry, brittle, thinning hair by stimulating keratin production and supporting new follicle growth. Vitamin C, an antioxidant, protects against oxidative stress and helps produce collagen, important for healthy hair, skin, and nails. Vitamin D helps create new hair follicles and is best obtained through supplementation and sunshine.

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The body may be deficient in vitamin D if experiencing low back pain, high blood pressure, depression, inflammation, or sleep issues like sleep apnea and snoring. Skin problems such as acne and dermatitis can also indicate a deficiency. Surprisingly, autoimmune diseases may also signal a need for more vitamin D. It is claimed that sufficient vitamin D3 intake can induce remission in autoimmune conditions.

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The inside of your eye is yellow according to, iridology, which is the study of the eye as it relates to health. When the corner of the eye is yellow, that can be a sign of liver stagnation. Another one, you can look at the bottom of your feet. So bottom of your feet, when they're dry and cracking, is showing that you're not getting proper circulation down to your feet. And so it can be a possibility that the liver is not doing a good job of detoxing and getting toxins out. So your circulatory system has more sludge in it. So the circulation isn't freely getting down to the bottom of your feet.

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Swollen feet that leave an indentation when pressed, known as pitting edema, can indicate underlying health issues. Edema may point to diabetes, kidney problems, or liver problems. The speaker recounts experiencing pitting edema at a younger age due to an unhealthy liver. The speaker, now almost six years old, no longer has pitting edema. Edema in the feet should make one consider the liver.

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When dealing with eczema, consider the health of your liver. Focus on avoiding alcohol, caffeine, processed sugar, dairy, wheat, and processed foods. Opt for whole foods to support your liver's cleansing function and overall health.

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- Jaundice: yellowing of the skin; bilirubin not cleared by the liver; scleral icterus. - Palmar erythema: redness of the palms; associated with pregnancy or hereditary conditions; when the liver is not breaking down estrogen it tends to build up and it can cause this. - Spider angioma: blood vessels underneath the skin resembling the legs of a spider; seen in liver disease. - Ascites: distended abdomen with fluid; when liver disease, this liquid leaves the vessels and fills the belly's cavity and can present with a tense belly or pain. - I'm a board certified gastroenterologist and liver specialist, so hit that follow button for more tips like this.

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itchiness, especially in your feet fatigue or lethargy belly fat because the liver is filling up with fat and it's spilling off into areas around the organs and in the organs in your abdomen Diabetes and prediabetes and insulin resistance, which comes before both of those things. Hormonal imbalances, especially with estrogen, testosterone, which have all sorts of cascade issues from hair loss to menstrual cycle issues to menopausal problems. Many different types of skin problems occur because of the liver. Joint issues, like especially arthritis, stiffness, and the things related to the gallbladder, like belching, burping, bloating, gallstones, as well as hypothyroidism, because we need a healthy liver to convert at least 80% of the thyroid from T4, the inactive, to T3, the active form of the thyroid hormone.

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Excessive sweating at night, even in a cool environment, can indicate a vitamin D deficiency. This may manifest as a moist pillow in the morning.

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If you're waking between 1AM and 3AM, your liver might need extra support. Research shows that detoxification has a huge link to our circadian rhythm. This means that waking up in the middle of the night could be linked to your liver. The liver is the key organ for detoxification. The liver naturally does most of its detoxification when you're in your deep non REM sleep, around 12AM to 3AM. It processes and metabolises cholesterol, fatty acids, glucose, thyroid hormones, bile acids, iron, and everything in between. So if your liver is congested or imbalanced, this can affect your wake sleep cycle, your sleep rhythm. Does this sound like it relates to you? Do you think that your liver could be playing a role in the way you sleep or in the way your sleep is being disturbed?

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The speaker discusses color signs related to liver health and what they might mean. He states that yellow skin is jaundice and that jaundice is a liver problem. He then notes that if the skin is slightly orange, that could also be jaundice, or it could be pigment from consuming large amounts of carrot juice. He shares a personal anecdote from his late 20s, describing how he was drinking a massive amount of carrot juice and literally turned orange, explaining that this orange tint was just pigment coming from the carrots and not a liver problem. The speaker then mentions red palms, a condition called palmar erythema, describing it as a sign that there is something wrong with the liver.

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If you have psoriasis, it's not just a skin problem, but a gut issue. Psoriasis is linked to an imbalanced immune system, often caused by gut problems like leaky gut or dysbiosis. Creams provide temporary relief, but to heal psoriasis, you must address the root cause in the gut by identifying triggers, removing them, and improving gut health with nutrition and supplements. Focus on healing your belly to heal your skin. Seek guidance from a functional medicine provider for support in this journey.

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Liver contains biotin, which can improve hair structure, making it thicker, stronger, more elastic, and fuller-looking, while also promoting hair growth. Obtaining biotin from grass-fed liver is superior to supplementation. If hair problems arise after antibiotic use, increasing biotin intake, specifically through grass-fed liver, is recommended. The speaker aimed to provide information on important foods for hair health.

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I remember I used to have dry eyes really bad to the point where my eyes were sticky. It affected my vision. And one time I opened my eyes and it tore my cornea. So I had a long history of problems with my eyes, especially being dry. And of course, I had a gallbladder problem for twenty years, had no clue who's my gallbladder. Gallbladder problems refer pain to the right shoulder, right? And when you have a gallbladder problem, many times you're deficient in bile and you can't absorb the fat soluble vitamins, and vitamin A is one big one. And so you may notice this either in dry eyes or a lack of vision in the evening when it's dark when you're trying to drive.

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Are you having digestive issues? The number one place is not to look to your digestive tract. The liver has a profound digestive component to it. The gallbladder, if you still have one, is attached to your liver. Your liver makes something called bile and then that bile gets excreted or pumped out into your small intestine after your food leaves your stomach. If the liver is sluggish, digestion is the first task that it throws out the back door. The liver enzymes to look at: ALT, AST, bilirubin, alkaline phosphatase, albumin. Not sleeping well between two and 4AM is described as a liver active time. For more info, click the link below.

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Six warning signs that you should do a liver detox include red or yellow eyes, potential yellowing skin, and chronic headaches that may cause nausea. Tight trapezius muscles, itchy skin, fatigue, lack of energy, weight gain, bloating, and light floating stools are also indicators. Milk Thistle is recommended as an herbal medicine to help cleanse the liver. Follow for more tips on how to stay healthy and detox with a full body detox.

The Peter Attia Drive Podcast

#46–Chris Masterjohn, Ph.D.: Pathways to health and disease (NAD, sirtuins, methylation, choline...
Guests: Chris Masterjohn
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In this episode of The Drive, Peter Attia interviews Chris Masterjohn, a nutrition scientist with a PhD, discussing various topics related to nutrition, health, and longevity. The conversation begins with Attia explaining the podcast's ad-free model, emphasizing the importance of trust and the value of listener support. He highlights the extensive research and resources that go into creating the podcast, including detailed show notes. The discussion shifts to choline, where Masterjohn explains its critical role in preventing non-alcoholic fatty liver disease (NAFLD) and its importance in methylation processes. Choline deficiency can lead to severe health issues, including fatty liver, which is becoming increasingly prevalent in the U.S. Attia and Masterjohn delve into the mechanisms of fatty liver disease, emphasizing the need for adequate choline intake to facilitate fat export from the liver. They also explore the MTHFR and COMT genes, which are involved in methylation and neurotransmitter metabolism. Masterjohn discusses how variations in these genes can affect individuals' methylation capacity and overall health, particularly in relation to homocysteine levels. He notes that individuals with certain MTHFR mutations may require higher choline intake to maintain metabolic health. The conversation touches on the use of nicotinamide riboside (NR) and its potential benefits and drawbacks. Masterjohn expresses skepticism about the efficacy of NR supplements, particularly regarding their impact on methylation and homocysteine levels. He suggests that while some individuals report positive effects from NR, the underlying biochemical mechanisms remain unclear, and the potential for increased methyl donor depletion is a concern. Attia and Masterjohn discuss the importance of dietary sources of choline, such as eggs and liver, and the role of creatine in supporting methylation processes. They emphasize the need for a balanced approach to supplementation, considering individual genetic variations and dietary habits. Throughout the episode, Masterjohn shares insights into the complexities of nutrition science, the importance of understanding individual biochemistry, and the need for more research to clarify the effects of various supplements on health outcomes. The conversation concludes with a discussion on the importance of personalized nutrition and the potential benefits of a holistic approach to health.
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