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Many people are vitamin D deficient, leading to increased risks of depression, Parkinson's, Alzheimer's, and cancer. Supplementing vitamin D alone won't help if you're eating poorly, not exercising, smoking, or drinking excessively. However, in an otherwise healthy lifestyle, correcting low vitamin D can make a big difference. It's important to consider context, as magnesium is crucial for converting vitamin D into its active form. About 50% of people don't get enough magnesium from sources like dark leafy greens, pumpkin seeds, dark chocolate, and almonds. Stress, coffee, alcohol, and sugar deplete magnesium levels. Magnesium is an anti-aging macro-mineral involved in DNA repair enzymes.

Low B vitamins and DHA can cause cognitive issues. One person experienced improved motivation after addressing a B12 deficiency. Vitamin B12 is essential and must be obtained from external sources like meat, eggs, or supplements. A high dose of vitamin C, zinc, and B12 can help the body fight off illness. One person recommends Nuzava B12 drops, suggesting viewers purchase them to avoid deficiency while they are still in stock.

B vitamins are recommended for low energy, as they deplete during stress. Vitamin B12 is particularly important, and adenosylcobalamin is the preferred form because it directly supports mitochondrial function, which produces energy. Sunlight exposure, grounding, and cold exposure, such as cold showers, can also boost mitochondrial function and energy levels.

Brain fog originates in the mitochondria, the energy factories within brain cells. The brain has more mitochondria than any other organ, utilizing 20% of the body's energy. Mitochondria generate energy from glucose using CoQ10 and from fat using acetylcarnitine. Mitochondrial dysfunction can starve brain cells, and is evident in neurodegenerative diseases before symptoms manifest. The speaker faced threats for using CoQ10 for hospital patients, despite its Nobel Prize recognition. The speaker recommends daily supplementation with CoQ10 1000mg, acetyl L-carnitine 1000mg, and PQQ 20mg to support brain energy.

Dr. Alexis Cohen (Jasmine Cohen) and the host discuss a wide-ranging view of health, science, and society, centered on mitochondria, light biology, and decentralized approaches to knowledge and healing. - On science, health, and authority: - Cohen argues that “we really haven’t been doing science for about seventy years now” and that modern science has become scientism, with people looking to scientists and doctors as authority figures over personal health, even though no one can fully know another’s lived body experience. - She emphasizes that aging is a reflection of mitochondrial heteroplasmy and that there are ways to slow or speed that burden, but contemporary living habits harm mitochondrial health. She asserts there are incentives to promote lifestyle advice that is not monetizable (outdoor activity, barefoot grounding, seasonal eating, movement), which she says slows research and access to information. - The conversation asserts a need to reclaim personal authority over health and to recognize life as magical and miraculous. - Personal entry into Bitcoin and crypto curiosity: - Cohen notes she and her partner became interested in Bitcoin in 2018, with a continued engagement including taking a cryptography course to understand the underlying proofs rather than accepting information at face value. - Background and work: - The host introduces Cohen as a Princeton-trained molecular biologist, a PhD focusing on metabolism, gut health, and circadian biology, who shifted from academic research to helping people rebuild health through nutrition, movement, mitochondrial function, and light exposure. Cohen shares that her own childhood illnesses, weight issues, and colitis prompted a pivot from academia to health coaching, emphasizing ownership of wellbeing through science and practical lifestyle strategies. - Cohen highlights that she values rigorous science but seeks practical lifestyle strategies to empower clients to understand their biology and take ownership of their health. - Dance, embodiment, and biology: - Cohen describes taking up social dancing (salsa, bachata, merengue, fox trot, hustle) and training intensely. She explains dancing challenges the brain in novel ways, requires being guided by a partner, and expands neural connections. - The host shares similar experiences with dance, noting body memory across decades and the importance of movement, rhythm, and social connection for health. - Mitochondria, heteroplasmy, and light: - Cohen explains mitochondria as the battery of the cell, with their own circular DNA and multiple roles in ATP production, biosynthesis, and epigenetic regulation. Heteroplasmy, the mutation burden in mitochondrial DNA, reflects dysfunction that can lead to energy production deficits across tissues. - She notes three key mitochondrial outputs: - ATP production powers cellular processes and metabolism. - Metabolic water production (including deuterium-depleted metabolic water). - Biophotons, photons largely in the UV range, emitted by mitochondria and nucleus during electron transport; older, sicker individuals emit more light due to increased permeability of the system. - Cohen argues aging mirrors mitochondrial heteroplasmy and mutation accumulation, with higher mutation burdens in tissues like immune cells, gut, liver, and brain associated with disease. She also discusses that mitochondria contribute to energy, water, and biophotons, and that modern life elevates heteroplasmy by lifestyle choices. - She argues heteroplasmy can be slowed or sped, and that there are actionable interventions—though the exact list is not exhaustively enumerated in this segment. - Why mitochondrial health isn’t the central target: - Cohen says mitochondrial health research is less profitable because it emphasizes lifestyle and environmental changes rather than drugs, which affects funding and research direction. She describes a system where focusing on broad environmental and lifestyle changes could be financially less lucrative than drug-centered approaches. - She expands on historical dynamics in science, including siloing of scientists and the development of a paywalled academic publishing model, suggesting that the system discourages holistic, integrative approaches that would unify mitochondrial biology with systems biology. - Light, circadian biology, and UVA/UVB: - The discussion shifts to light as a regulator of mitochondria. Cohen divides the sun’s spectrum into ultraviolet (UVB and UVA), visible light, blue light, and near infrared (NIR). She emphasizes that near-infrared light penetrates deeply and stimulates mitochondria, while UVB promotes melanin production via POMC and MSH peptides, affecting energy balance, mood, and metabolism. - UVB light triggers alpha-MSH and beta-endorphin production, the latter contributing to mood and dopamine support, and helps regulate energy expenditure and appetite via POMC-derived pathways; UVB exposure supports melanin synthesis, redox balance, and photoreception across tissues. - UVA light activates Neuropsin receptors on eyes and skin, aiding circadian entrainment and nitric oxide production, which improves vasodilation and nutrient delivery. Neuropsin is present in skin and testes; its stimulation is linked to testosterone and fertility enhancements. UVA also helps anchor local circadian rhythms in tissues. - Cohen discusses the misperception that UV light is universally harmful and argues that melanin is not only protective but can facilitate energy capture from high-energy photons to support energy metabolism in humans. Melanin’s roles extend beyond protection to potential energy transduction, with POMC, MSH, and alpha-MSH linking light exposure to metabolic regulation. - The My Circadian app is recommended as a tool to track sunrise, UVA/UVB rise, and lux (brightness) to optimize exposure. Cohen notes indoor environments rarely exceed 1000 lux, while outdoor brightness can reach 60,000–60,200 lux, significantly impacting serotonin production, mood, and cognition. She emphasizes the importance of bright daytime light for circadian alignment and melatonin suppression at night. - Infrared, LEDs, and indoor lighting: - The conversation covers lighting technologies, noting fluorescent tubes and LEDs minimize near-infrared and maximize blue light, which disrupts circadian rhythms and flicker, stressing the eyes and sympathetic nervous system. Cohen argues that modern lighting deprives people of infrared and UV radiation, both critical for mitochondrial function and circadian health. - She criticizes the push for energy efficiency that reduces thermal and infrared energy, arguing it contributes to systemic health issues. She emphasizes the importance of incandescent and near-infrared-rich lighting for indoor environments and sun exposure to sustain metabolic health. - Grounding, EMF, and environmental exposure: - Grounding (direct contact with the earth) is presented as a way to discharge excess positive charge in tissues, reducing inflammatory burden and supporting mitochondrial function. Cohen shares practical grounding instructions—grounding directly to the earth when possible, wearing natural fibers, and using grounding footwear. - Non-native electromagnetic fields (EMFs) from Wi-Fi, Bluetooth, 5G, and other sources are discussed as contributors to mitochondrial dysfunction and inflammation. Cohen cites Robert Becker’s historical work on non-thermal EMF effects and Havana syndrome as context for potential biological risks. She suggests practical mitigation, including reducing EMF exposure, using Ethernet where possible, and using tinfoil to shield exposure in certain situations. Plant life can absorb EMF, and grounding, sunlight, and strategic use of red and infrared light are recommended to compensate where exposure is high. - The discussion includes practical home strategies, EMF-blocking window panels, EMF-blocking paint, and even temporary shielding (e.g., tinfoil) as a do-it-yourself mitigation approach. - Travel, circadian disruption, and protocols: - Cohen outlines travel challenges: high altitude cosmic radiation exposure (non-AVMF exposure), cabin EMFs, circadian misalignment, and sedentary behavior. She suggests pre- and post-travel strategies such as grounding, sun exposure, hydration, lymphatic support, and blue-light management to ease time-zone transitions. - She promotes an ebook protocol focused on lymphatic support and circadian realignment, available for purchase, with a holiday discount code holydays. Blue-light blocking strategies and red-light strategies are included to facilitate adaptation to new time zones. - Health, mental health, and pediatric considerations: - The hosts discuss mental health concerns, including PTSD, anxiety, and depression, emphasizing circadian regulation, light exposure, sleep hygiene, and reducing screen exposure. Cohen notes the importance of bright daytime light and a dark, cool sleeping environment for sleep quality and mood. She mentions a study showing even small nighttime light exposure can influence daytime metabolic markers, emphasizing the importance of darkness at night. - Birth, medications, and vaccines: - They touch on birth experiences, epidurals, and how early life interventions can influence long-term health and microbiome development. Cohen discusses pain as a portal to healing and critiques reliance on certain pharmaceutical approaches. - On vaccines, Cohen describes observed adverse effects post COVID-19 vaccination, including histamine issues, barrier permeability, and rapid cancer reports linked to vaccine exposure, while underscoring the lack of widespread funding to investigate these relationships. She mentions turbo cancers and batch variation as topics already discussed by researchers like Kevin McKernan and a need for independent inquiry. - Decentralization, science, and Bitcoin again: - Cohen envisions a decentralized health system in which multiple modalities (acupuncture, Chinese medicine, Ayurveda, allopathic medicine) can be tested for proof of work, with outcomes guiding what works best for individuals. She believes decentralization is necessary for genuine innovation, with a future vision of a decentralized, funded light research lab and a retreat model to study circadian biology, mitochondrial function, and nature-based health in diverse environments (North America and equatorial regions). - She sees Bitcoin as a tool that enables financial sovereignty and autonomy, providing an opportunity to fund decentralized science and publish findings on blockchain to protect against censorship. She highlights the potential for Bitcoin to support a lab through deflationary funding and to empower researchers and patients alike. - Closing: - The conversation closes with practical resources: Thinkific-hosted classes, an online book club, and a QuantumU course that reframes science education around decentralized, nature-based principles. Cohen emphasizes accessible contact options (Instagram and email) and a holiday discount for courses and ebooks. The participants express enthusiasm for ongoing collaboration, travel and events, and continued education in Bitcoin, science, and holistic health. Overall, the episode centers on mitochondria as a foundational health driver, the essential role of light and circadian biology in energy, mood, metabolism, and aging, and a call for decentralized, nature-aligned science, with Bitcoin framed as a funding and governance tool to empower individuals and researchers to pursue health innovation beyond centralized institutions.

Mitochondria generate energy via ATP, but new research suggests they are more than just energy factories; mitochondrial dysfunction is linked to diseases like diabetes, autism, and cancer. To support mitochondria, one must stress them through hormesis, where "what doesn't kill you makes you stronger." Five ways to stress mitochondria include: intermittent fasting (practiced differently by men and women), cold exposure (cold showers or cryotherapy), sauna (heat exposure activates heat shock proteins), exercise, and gratitude. Research indicates happier people are healthier, and being in a grateful state activates the parasympathetic nervous system, balancing the autonomic nervous system. Gratitude, or "vitamin G," may contribute to healthier mitochondria.

High intensity interval training has been shown to significantly boost NAD production. Whether it's cold showers or ice baths stimulates NAD activity, improving cellular resilience.

Speaker 0: The discussion centers on mitochondria as the energy factory of the cell and how a shortened lifespan can stem from problems with this organelle. There are a few factors and variables involved: the quality of the fuel entering the mitochondria, and the biochemical reactions that take that food and extract different things to turn it into energy, specifically in the form of ATP, at the end of this entire assembly line. Every single biochemical reaction that occurs inside this system requires vitamins, minerals, and trace minerals. Nutrition is essential for proper mitochondrial function, with specific nutrients highlighted as critical: B1, B2, B3, B5, Coenzyme Q10, and the trace minerals manganese, zinc, iodine, copper, and magnesium. The speaker emphasizes that these elements are vitally important for the mitochondria to function. The implication is that without these nutrients, the mitochondria will not operate well. In contrast, consuming too much junk food is suggested to impair mitochondrial function, contributing to dysfunction. The overall message is that there can be a couple of reasons why the mitochondria do not function correctly, including inadequate or imbalanced nutrition and excessive junk food intake, which can disrupt the energy production process that mitochondria are responsible for.

Low energy is a common sign of a vitamin D deficiency because your mitochondria, which is the part of the cells where your energy actually comes from, rely on vitamin D to work properly. If you're low in vitamin D because you're not getting outside and getting your skin exposed to the sun, your mitochondria don't work as well, which can leave you feeling weak, fatigued, and low in energy. Vitamin D deficiency is one of the most common deficiencies across the planet. If you're suffering from low energy, really look at your lifestyle and see if you're getting outside and getting your skin exposed to the sun. If not, this would be the first place to start if you want to increase your energy levels.

Vitamin B12 is essential for red blood cell production, which transports oxygen throughout the body. A vitamin B12 deficiency leads to a decrease in red blood cells, reducing oxygen delivery to body tissues. This can result in weakness, fatigue, and exhaustion.

Vitamin B12 is essential for red blood cell production, which transports oxygen throughout the body. A vitamin B12 deficiency leads to a decrease in red blood cells, reducing oxygen delivery to body tissues. This can result in weakness, fatigue, and exhaustion.

To manage stress, prioritize keeping stress levels low, increasing sleep and exercise, and regularly taking Vitamin B1. Nutritional yeast is a recommended source for B1. Identifying and addressing the root cause of stress is also crucial.

Rhodiola, an arctic herb, may combat mental exhaustion by activating AMPK, the brain's energy sensor, and balancing stress hormones. It enhances neuronal glucose utilization and protects against stress-related damage, specifically targeting mental fatigue and cognitive burnout. Research indicates that rhodiola can boost mental performance by 35% during periods of stress and fatigue. It also reduces errors in cognitive tasks and accelerates processing speed. For optimal results, take 400 milligrams of rhodiola in the morning, but not after 2 PM to avoid sleep disruption. Cycle with five days on and two days off.

Mitochondria are cells that function as battery-making machines, producing ATP, the body's energy currency. The body makes its weight in ATP daily, but ATP is not stored; it's made on demand. To increase energy levels, it's important to support mitochondria with cofactors like B vitamins, magnesium, zinc, and coenzyme Q10, as well as specific foods. For more information on increasing energy, the speaker recommends watching their YouTube video on fatigue.

Being low on B vitamins or DHA can cause cognitive issues. Vitamin B12 is an essential vitamin that the body cannot produce, so it must be obtained through food like meat and eggs, or through supplementation. A B12 deficiency can range from mild to severe. High doses of vitamin C, zinc, and B12 can help the body fight off sickness. B12 is good for fighting a cold. Nuzava B12 drops are recommended and available while the orange shopping cart is visible.

The mitochondria is a pre battery machine. It actually makes a lot of batteries and that battery is ATP. Did you realize that your body actually makes your weight in ATP every single day? ATP is the energy currency of the body, and ATP is not stored. It's made on demand. Unless you understand it and support it with all the cofactors like b vitamins, magnesium, zinc, coenzyme q ten, as well as certain foods that will help build the mitochondria, you may find that you're never able to get your energy past a certain point. Now, if you really want to take your energy to the next level, search out my video on YouTube that I just released on fatigue. And in that video, I'm gonna show you exactly what to do.

Mitochondria generate energy, but also possess intelligence and DNA. Mitochondrial dysfunction is linked to diseases like diabetes, autism, and cancer. To support mitochondria, you must stress them through hormesis, where "what doesn't kill you makes you stronger." Five ways to stress mitochondria include: intermittent fasting, which men and women practice differently; cold exposure via cold showers or cryotherapy; sauna use to activate heat shock proteins; exercise to create energy demand; and gratitude, which activates the parasympathetic nervous system. Research suggests happier people are healthier, and being in a grateful state balances the autonomic nervous system. Gratitude is "vitamin G."