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Adequate sleep and cortisol reduction are the most impactful ways to naturally increase testosterone production, potentially by 300-400 ng/dL. Hypercortisolemia stress has the greatest negative behavioral impact on endogenous testosterone production. Poor sleep and high stress can easily lead to hypogonadism. Addressing these issues is more beneficial than supplements with marginal benefits. This advice is specific to men.

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Instead of focusing on the negative, let's look at some positive things that you're already doing that are positively impacting testosterone levels. There was a study published in the journal Endocrine that showed that simply walking more than 8,000 steps per day showed a seriously decreased risk of hypogonadism. Good old fashioned squats. There's a study published in the Canadian Journal of Applied Physiology that showed that simply squatting to failure could increase testosterone levels significantly for one to two hours post workout. Soaking up the sun as much as you can, study in cell reports demonstrated there's something called the skin brain gonadal axis, demonstrating that there's something called the p 53 gene that associates with UVB light translating into our testosterone levels.

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The number one anti-aging therapy is sunlight, not Botox or collagen. Regular, sufficient sun exposure provides vitamin D and nitric oxide, which aids circulation. Over 50% of sun rays provide infrared, supporting the mitochondria and offering antioxidant effects. Sunlight naturally helps increase testosterone, estrogen, and brain-derived neurotrophic factor.

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Dr. Alexis Cohen (Jasmine Cohen) and the host discuss a wide-ranging view of health, science, and society, centered on mitochondria, light biology, and decentralized approaches to knowledge and healing. - On science, health, and authority: - Cohen argues that “we really haven’t been doing science for about seventy years now” and that modern science has become scientism, with people looking to scientists and doctors as authority figures over personal health, even though no one can fully know another’s lived body experience. - She emphasizes that aging is a reflection of mitochondrial heteroplasmy and that there are ways to slow or speed that burden, but contemporary living habits harm mitochondrial health. She asserts there are incentives to promote lifestyle advice that is not monetizable (outdoor activity, barefoot grounding, seasonal eating, movement), which she says slows research and access to information. - The conversation asserts a need to reclaim personal authority over health and to recognize life as magical and miraculous. - Personal entry into Bitcoin and crypto curiosity: - Cohen notes she and her partner became interested in Bitcoin in 2018, with a continued engagement including taking a cryptography course to understand the underlying proofs rather than accepting information at face value. - Background and work: - The host introduces Cohen as a Princeton-trained molecular biologist, a PhD focusing on metabolism, gut health, and circadian biology, who shifted from academic research to helping people rebuild health through nutrition, movement, mitochondrial function, and light exposure. Cohen shares that her own childhood illnesses, weight issues, and colitis prompted a pivot from academia to health coaching, emphasizing ownership of wellbeing through science and practical lifestyle strategies. - Cohen highlights that she values rigorous science but seeks practical lifestyle strategies to empower clients to understand their biology and take ownership of their health. - Dance, embodiment, and biology: - Cohen describes taking up social dancing (salsa, bachata, merengue, fox trot, hustle) and training intensely. She explains dancing challenges the brain in novel ways, requires being guided by a partner, and expands neural connections. - The host shares similar experiences with dance, noting body memory across decades and the importance of movement, rhythm, and social connection for health. - Mitochondria, heteroplasmy, and light: - Cohen explains mitochondria as the battery of the cell, with their own circular DNA and multiple roles in ATP production, biosynthesis, and epigenetic regulation. Heteroplasmy, the mutation burden in mitochondrial DNA, reflects dysfunction that can lead to energy production deficits across tissues. - She notes three key mitochondrial outputs: - ATP production powers cellular processes and metabolism. - Metabolic water production (including deuterium-depleted metabolic water). - Biophotons, photons largely in the UV range, emitted by mitochondria and nucleus during electron transport; older, sicker individuals emit more light due to increased permeability of the system. - Cohen argues aging mirrors mitochondrial heteroplasmy and mutation accumulation, with higher mutation burdens in tissues like immune cells, gut, liver, and brain associated with disease. She also discusses that mitochondria contribute to energy, water, and biophotons, and that modern life elevates heteroplasmy by lifestyle choices. - She argues heteroplasmy can be slowed or sped, and that there are actionable interventions—though the exact list is not exhaustively enumerated in this segment. - Why mitochondrial health isn’t the central target: - Cohen says mitochondrial health research is less profitable because it emphasizes lifestyle and environmental changes rather than drugs, which affects funding and research direction. She describes a system where focusing on broad environmental and lifestyle changes could be financially less lucrative than drug-centered approaches. - She expands on historical dynamics in science, including siloing of scientists and the development of a paywalled academic publishing model, suggesting that the system discourages holistic, integrative approaches that would unify mitochondrial biology with systems biology. - Light, circadian biology, and UVA/UVB: - The discussion shifts to light as a regulator of mitochondria. Cohen divides the sun’s spectrum into ultraviolet (UVB and UVA), visible light, blue light, and near infrared (NIR). She emphasizes that near-infrared light penetrates deeply and stimulates mitochondria, while UVB promotes melanin production via POMC and MSH peptides, affecting energy balance, mood, and metabolism. - UVB light triggers alpha-MSH and beta-endorphin production, the latter contributing to mood and dopamine support, and helps regulate energy expenditure and appetite via POMC-derived pathways; UVB exposure supports melanin synthesis, redox balance, and photoreception across tissues. - UVA light activates Neuropsin receptors on eyes and skin, aiding circadian entrainment and nitric oxide production, which improves vasodilation and nutrient delivery. Neuropsin is present in skin and testes; its stimulation is linked to testosterone and fertility enhancements. UVA also helps anchor local circadian rhythms in tissues. - Cohen discusses the misperception that UV light is universally harmful and argues that melanin is not only protective but can facilitate energy capture from high-energy photons to support energy metabolism in humans. Melanin’s roles extend beyond protection to potential energy transduction, with POMC, MSH, and alpha-MSH linking light exposure to metabolic regulation. - The My Circadian app is recommended as a tool to track sunrise, UVA/UVB rise, and lux (brightness) to optimize exposure. Cohen notes indoor environments rarely exceed 1000 lux, while outdoor brightness can reach 60,000–60,200 lux, significantly impacting serotonin production, mood, and cognition. She emphasizes the importance of bright daytime light for circadian alignment and melatonin suppression at night. - Infrared, LEDs, and indoor lighting: - The conversation covers lighting technologies, noting fluorescent tubes and LEDs minimize near-infrared and maximize blue light, which disrupts circadian rhythms and flicker, stressing the eyes and sympathetic nervous system. Cohen argues that modern lighting deprives people of infrared and UV radiation, both critical for mitochondrial function and circadian health. - She criticizes the push for energy efficiency that reduces thermal and infrared energy, arguing it contributes to systemic health issues. She emphasizes the importance of incandescent and near-infrared-rich lighting for indoor environments and sun exposure to sustain metabolic health. - Grounding, EMF, and environmental exposure: - Grounding (direct contact with the earth) is presented as a way to discharge excess positive charge in tissues, reducing inflammatory burden and supporting mitochondrial function. Cohen shares practical grounding instructions—grounding directly to the earth when possible, wearing natural fibers, and using grounding footwear. - Non-native electromagnetic fields (EMFs) from Wi-Fi, Bluetooth, 5G, and other sources are discussed as contributors to mitochondrial dysfunction and inflammation. Cohen cites Robert Becker’s historical work on non-thermal EMF effects and Havana syndrome as context for potential biological risks. She suggests practical mitigation, including reducing EMF exposure, using Ethernet where possible, and using tinfoil to shield exposure in certain situations. Plant life can absorb EMF, and grounding, sunlight, and strategic use of red and infrared light are recommended to compensate where exposure is high. - The discussion includes practical home strategies, EMF-blocking window panels, EMF-blocking paint, and even temporary shielding (e.g., tinfoil) as a do-it-yourself mitigation approach. - Travel, circadian disruption, and protocols: - Cohen outlines travel challenges: high altitude cosmic radiation exposure (non-AVMF exposure), cabin EMFs, circadian misalignment, and sedentary behavior. She suggests pre- and post-travel strategies such as grounding, sun exposure, hydration, lymphatic support, and blue-light management to ease time-zone transitions. - She promotes an ebook protocol focused on lymphatic support and circadian realignment, available for purchase, with a holiday discount code holydays. Blue-light blocking strategies and red-light strategies are included to facilitate adaptation to new time zones. - Health, mental health, and pediatric considerations: - The hosts discuss mental health concerns, including PTSD, anxiety, and depression, emphasizing circadian regulation, light exposure, sleep hygiene, and reducing screen exposure. Cohen notes the importance of bright daytime light and a dark, cool sleeping environment for sleep quality and mood. She mentions a study showing even small nighttime light exposure can influence daytime metabolic markers, emphasizing the importance of darkness at night. - Birth, medications, and vaccines: - They touch on birth experiences, epidurals, and how early life interventions can influence long-term health and microbiome development. Cohen discusses pain as a portal to healing and critiques reliance on certain pharmaceutical approaches. - On vaccines, Cohen describes observed adverse effects post COVID-19 vaccination, including histamine issues, barrier permeability, and rapid cancer reports linked to vaccine exposure, while underscoring the lack of widespread funding to investigate these relationships. She mentions turbo cancers and batch variation as topics already discussed by researchers like Kevin McKernan and a need for independent inquiry. - Decentralization, science, and Bitcoin again: - Cohen envisions a decentralized health system in which multiple modalities (acupuncture, Chinese medicine, Ayurveda, allopathic medicine) can be tested for proof of work, with outcomes guiding what works best for individuals. She believes decentralization is necessary for genuine innovation, with a future vision of a decentralized, funded light research lab and a retreat model to study circadian biology, mitochondrial function, and nature-based health in diverse environments (North America and equatorial regions). - She sees Bitcoin as a tool that enables financial sovereignty and autonomy, providing an opportunity to fund decentralized science and publish findings on blockchain to protect against censorship. She highlights the potential for Bitcoin to support a lab through deflationary funding and to empower researchers and patients alike. - Closing: - The conversation closes with practical resources: Thinkific-hosted classes, an online book club, and a QuantumU course that reframes science education around decentralized, nature-based principles. Cohen emphasizes accessible contact options (Instagram and email) and a holiday discount for courses and ebooks. The participants express enthusiasm for ongoing collaboration, travel and events, and continued education in Bitcoin, science, and holistic health. Overall, the episode centers on mitochondria as a foundational health driver, the essential role of light and circadian biology in energy, mood, metabolism, and aging, and a call for decentralized, nature-aligned science, with Bitcoin framed as a funding and governance tool to empower individuals and researchers to pursue health innovation beyond centralized institutions.

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Lack of sleep can significantly decrease testosterone levels. A University of Chicago study found that young, healthy men who slept less than five hours a night experienced a 15% drop in testosterone. Sleeping around four hours a night can lower it even further. Adequate sleep is also crucial for proper immune function. Insufficient sleep is a risk factor for more severe or frequent illness, relevant in the current viral pandemic. Aim for six to eight hours of sleep per night. If only able to sleep six hours, a 20-30 minute daytime nap can help boost testosterone levels.

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Zinc, vitamin D, and magnesium are said to activate bodily processes that aid testosterone production. Deficiencies in any of these minerals, due to inadequate dietary intake of magnesium and zinc or insufficient sun exposure for vitamin D synthesis, may negatively affect testosterone levels. This can lead to problems with muscle mass, energy levels, and libido, all of which are reportedly influenced by testosterone.

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Here are five reasons to get sunlight for your health. First, UVB rays absorbed by the skin produce vitamin D, which is vital for many bodily processes. Second, light absorbed, especially by the eyes, increases serotonin production, improving mood. Third, sunlight, particularly in the early morning, affects the circadian rhythm, improving sleep. Fourth, sunlight improves immune function, specifically T-cell function, and vitamin D production also modulates immune activity. Fifth, UVA rays absorbed by the skin release nitric oxide, a vasodilator, which expands blood vessels and lowers blood pressure.

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Body fat reduces testosterone levels because testes-produced testosterone must be transported to receptor sites. Body fat converts testosterone into estrogen and disrupts testosterone transportation. Therefore, being fat turns men into women. Improving physiology improves psychology.

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UV light lowers blood pressure. UV light increases the efficiency of the heart. UV light improves EKG. UV light balances cholesterol. UV light assists in weight loss. UV light is a treatment for skin conditions. UV light is also an effective treatment for many disorders. Going back to light therapy of 1933 in Germany where they used to heal people with light, then you go UV light increases the level of hormones. People suffering from low testosterone or altered estrogen sitting in the sun. Then we go UV light activates important skin skin hormones such as vitamin d, natural sources. Now why do they tell people to stay out of the sun? Because all these industries exist to keep making money on the people. And if you tell people that UV is toxic and you better stay out of that sun, well, then these industries continue to keep just going about. And that's what we see because these industries have been going on for a long time. Hundred about a hundred years of being told lies. And all we're doing, debunking it one step at a time.

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The cheapest, quickest, and most effective way to naturally increase testosterone is to get more sun. Sunlight increases vitamin D production, which has a strong correlation with testosterone levels. Bright light exposure directly to the eyes signals the brain to initiate testosterone production. Additionally, various forms and wavelengths of sunlight have been shown to increase testosterone when directly exposed to the under parts.

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One night of sleep deprivation can reduce testosterone levels by 15%. A study showed that sleep deprivation reduces young men's testosterone levels equivalent to aging 10 to 15 years. One bad night of sleep can drop a 35-year-old's testosterone to the level of a 50-year-old. Aim for eight hours of quality sleep, but get a minimum of seven hours per night for health.

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Vitamin D, magnesium, and zinc activate the chemical reaction that converts cholesterol into testosterone. Deficiency in these nutrients is common, affecting a large percentage of the population. Low testosterone can lead to decreased libido, erectile dysfunction, muscle loss, increased risk of heart problems, depression, and bone loss. Vitamin D can be obtained from sun exposure, magnesium from leafy greens and pumpkin seeds, and zinc from oysters.

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Sunlight deficiency is claimed to be the biggest cause of disease, with studies suggesting avoiding the sun is as risky as smoking. Insufficient sun exposure is allegedly responsible for almost 400,000 deaths per year and an increased incidence of almost every disease. Vitamin D is described as critical for dopamine synthesis, mood, weight loss, immune function, and glucose metabolism. Vitamin D supplementation is associated with a claimed 40% lower rate of dementia, and 4,000 IU of vitamin D reportedly boosted testosterone 40% in one study. Beyond vitamin D, the sun purportedly shrinks fat cells and improves the gut microbiome. Red and near-infrared light from the sun is said to structure water in mitochondria, boosting energy production and setting the circadian rhythm.

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When men lack sleep, testosterone plummets. In this study, it was found that just five hours of sleep resulted in decreased testosterone by 10 to 15% in the men that were studied. So this we know dramatically lowers testosterone levels. This was in young healthy men because testosterone levels typically will peak between three and 8AM. So if you're not sleeping properly, you're not getting those eight hours of sleep minimum, then you are not having your optimized testosterone levels guys. So my tips here make sure that you're sleeping at least eight hours, get early morning sunlight in your eyes. Seeing that sunrise really important to make your melatonin for later at night for that proper sleep and never eat right before bed. That's gonna cause your digestion to be optimized and not your sleep. Follow for more natural health tips.

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It is claimed that declining testosterone levels are not inevitable with age. LDL cholesterol, often considered harmful, is essential for sex hormone synthesis. It must cross cell and mitochondrial membranes to reach the enzyme P450 SCC. This enzyme, activated by 450-nanometer blue light, cleaves cholesterol to create pregnenolone, the precursor to all other sex hormones. Since blue light cannot penetrate the skin, it is likely produced within the mitochondria during energy production. Therefore, stimulating mitochondrial activity may boost sex hormone production. Strategies to achieve this include exercise, magnesium and zinc supplementation, and cold plunge therapy to activate brown fat and stimulate mitochondrial production. These actions create light inside the cell that increases the activity of the critical enzyme where all sex hormone synthesis originates.

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The number one antiaging therapy is sunlight, not Botox, collagen, or anti-wrinkle creams. Regular, sufficient sun exposure provides vitamin D and nitric oxide, which aids circulation. Over 50% of sun rays provide infrared, supporting the mitochondria and producing antioxidant effects. Sunlight also naturally increases testosterone, estrogen, and brain-derived neurotrophic factor.

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Stress is identified as the primary driver of low testosterone levels and can negatively impact the thyroid, adrenal function, and sex hormones. Men should prioritize stress relief, even if they don't perceive themselves as stressed, by incorporating relaxation activities into their daily routine.

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Men with the lowest testosterone levels face a greater risk of mortality within five years. Testosterone is not just a hormone related to lifestyle and muscles, but it is also important for overall health and wellness. Maximizing testosterone naturally is a good approach, but when that's not possible, testosterone impacts more than just the commonly associated aspects.

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Lack of sleep causes a decrease in testosterone. A study found that five hours of sleep decreased testosterone by 10 to 15% in men. Testosterone levels typically peak between 3 and 8 AM, so not sleeping at least eight hours prevents optimized testosterone levels. Tips for better sleep include sleeping at least eight hours, getting early morning sunlight to help with melatonin production, and avoiding eating right before bed to optimize sleep instead of digestion.

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Zinc, vitamin D, and magnesium are claimed to activate bodily processes that produce testosterone. Deficiencies in any of these minerals, due to poor diet or lack of sun exposure, may negatively affect testosterone production. This can impact muscle mass, energy levels, and libido.

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Adequate sleep and cortisol reduction are the most impactful ways to naturally increase testosterone production, potentially by 300-400 ng/dL. Hypercortisolemia stress negatively impacts endogenous testosterone production, likely through the pituitary gonadal axis. Poor sleep and high stress can easily lead to hypogonadism. Addressing these issues is more beneficial than using supplements with marginal benefits. This advice is primarily for men.

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If you wanna maximize testosterone production, you need daily sunshine exposure for two primary reasons. Number one, vitamin D. Vitamin D is essential for testosterone production. Without it, testosterone can't be made. Secondly, daily sunshine exposure is super important for getting a good night's sleep. If you check my previous videos, you'll understand why sleep quality is so important for testosterone production. So how much sun do you need? In my opinion, be careful. Don't get burnt, but the more the better. Aim for twenty to thirty minutes in direct sunshine each day with minimal clothing.

Huberman Lab

Using Light (Sunlight, Blue Light & Red Light) to Optimize Health | Huberman Lab Podcast #68
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Welcome to the Huberman Lab podcast. I'm Andrew Huberman, a professor at Stanford, and today we will explore the powerful uses of light to optimize health, including skin health, hormone balance, sleep regulation, and even dementia offsetting. Light can be translated into electrical and hormonal signals in our bodies, impacting gene expression throughout our lifespan. I will provide specific protocols based on peer-reviewed literature to help you use different wavelengths of light for health benefits. Historically, the use of light in therapy is well-established, with the Nobel Prize awarded in 1903 for phototherapy in lupus treatment. Recent research from Dr. Glenn Jeffrey at University College London highlights red light therapy's potential to counter age-related vision loss. Brief exposures to red light early in the day can significantly improve vision in individuals over 40, as it enhances ATP production in metabolically active retinal cells. I will also announce two live events in May, focusing on mental and physical health tools. The podcast aims to provide zero-cost scientific information to the public, supported by sponsors like Athletic Greens, which offers foundational nutrients and probiotics, and Thesis, which creates custom nootropics for cognitive enhancement. Now, let's discuss the physics and biology of light. Light is electromagnetic energy with various wavelengths, impacting our biology at different levels. Longer wavelengths, like red and near-infrared light, penetrate tissues more effectively than shorter wavelengths like blue or ultraviolet light. This penetration allows light to influence cellular functions, including those in mitochondria, which produce ATP. Light can modulate biological signals through absorption by specific pigments in our cells. For example, photoreceptors in our eyes absorb light, enabling vision, while melanocytes in our skin respond to UV light, affecting pigmentation. Light exposure can have both direct effects on cells and indirect effects through signaling pathways. Melatonin, a hormone regulated by light exposure, plays a crucial role in sleep and seasonal biological rhythms. Light inhibits melatonin production, which varies with seasonal changes in daylight. For optimal health, it is essential to get appropriate sunlight exposure, particularly in the morning, to regulate melatonin and support overall well-being. During winter months, individuals may experience seasonal affective disorder (SAD). Bright light exposure can help mitigate this condition. It's advisable to limit bright light exposure at night to maintain healthy melatonin levels. Using dim red or amber light at night can help avoid melatonin suppression. Research shows that UVB light exposure can enhance mood, increase testosterone and estrogen levels, and improve immune function. Regular UVB exposure can also accelerate wound healing and promote hair growth. The skin acts as an endocrine organ, responding to light and influencing hormonal pathways. Low-level light therapy (LLLT) using red and near-infrared light has shown promise in treating skin conditions like acne and promoting healing. These therapies work by enhancing mitochondrial function and reducing reactive oxygen species in cells. Recent studies indicate that red light therapy can improve visual function in older adults by enhancing ATP production in retinal cells and reducing age-related degeneration. The Jeffrey lab's research demonstrates that just a few minutes of red light exposure can lead to significant improvements in visual acuity. Additionally, Li-Huei Tsai's work at MIT shows that flickering light at specific frequencies can induce gamma oscillations in the brain, promoting neuroprotection and reducing Alzheimer's-related markers. This non-invasive approach could lead to new therapies for cognitive decline. In summary, light has profound effects on our biology, influencing hormones, mood, immune function, and cellular health. By understanding and applying these principles, we can harness the power of light to enhance our well-being. Thank you for joining me today, and I look forward to sharing more insights in future episodes.

No Lab Coat Required

Did you fall for this vitamin D trick?
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Vitamin D3 is the most purchased and consumed vitamin, advertised as essential for immunity. Vitamin D is known for its immunomodulatory, anti-inflammatory, antiviral, antioxidative properties. The sun is the most efficient method to get vitamin D, yet doctors may prescribe supplements, prompting the vitamin D paradox. Vitamin D testing surged from 2000 to 2010, an 83-fold increase, while cod liver oil early in the 1930s led to fortifying milk and eradicating rickets. The narrative shifted from sunlight to pills, fueled by capitalism and marketing. UVB triggers vitamin D synthesis in the skin; UVA interacts with melanin. Umelanin and fmelanin determine protection and vitamin D absorption; more melanin means more protection but less D production. Vitamin D is fat-soluble and stored, released as needed by sequestration. Modern indoor life and migration reduce sun exposure, contributing to vitamin D deficiency—especially among Black Americans. There is no healthy tan; sunlight also influences ghrelin, mood, and blood pressure.

Huberman Lab

Using Light to Optimize Health | Huberman Lab Essentials
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Light is described as a pervasive biological signal that the body translates into electrical, hormonal, and genetic activity. The host explains how different wavelengths of light penetrate tissues to varying depths and how photoreceptors in the eye, along with skin cells, relay light information to brain circuits and endocrine systems. A key emphasis is that light exposure influences melatonin production via intrinsically photosensitive melanopsin cells, linking daily and seasonal cycles to sleep, mood, and overall physiology. The discussion highlights how melatonin serves as a transducer of environmental light, guiding physiological timing across the year, and notes that bright indoor light can suppress melatonin with consequences for sleep, mood, and circadian alignment. The host also covers how exposure to ultraviolet B light through the skin or eyes can acutely raise sex hormones, affect fertility markers, and alter mate behavior in animal models, while acknowledging differences in humans. The broader point is that light signals modulate regulatory and protective hormonal processes, immune function, and tissue renewal, with seasonal patterns shaping experiences of energy and well-being. Practical guidance includes balancing outdoor light exposure across seasons, considering blue-light blocking, and using devices like light panels or SAD lamps to support mood and circadian health in darker months. Cautions are raised about excessive bright light, especially at night, and about individual risk factors for skin or eye disease when increasing UV exposure. The overview also touches how red and near-infrared light can penetrate deeper tissues to influence mitochondria, boost ATP, reduce reactive oxygen species, and potentially support skin healing and neuronal function, including research in aging vision and the potential for improving older adults’ visual performance.
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