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Based on my experience, I want to emphasize that the next administration will definitely face challenges related to infectious diseases. This includes managing existing chronic infectious diseases, which already pose a significant burden. However, more importantly, be prepared for a surprise outbreak. It's not a matter of if, but when, so pandemic preparedness is crucial.

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We must remain vigilant about current diseases, but an even greater danger lies in fixating on the last pandemic when preparing for future threats. Emerging infections can arise from various sources, and we are still susceptible to the intentional spread of diseases by those who seek to cause harm. Our global community faces numerous potential health threats.

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Vaccines are crucial for public health. There will be new vaccines developed, including for TB, malaria, and HIV. Misinformation about vaccines is a problem, especially in the US. We need to invest in vaccinations, as it has a significant return on investment. Life will not fully return to normal until the global population is vaccinated. We must prepare for future pandemics.

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Based on my experience, I want to emphasize that the upcoming administration will face challenges in the field of infectious diseases. These challenges include both chronic diseases that are already prevalent and new outbreaks. It is certain that there will be a surprise outbreak in the future.

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I have served in 5 administrations and want to emphasize that the next administration will face challenges in infectious diseases. There will be both chronic diseases and surprise outbreaks. History shows that these challenges are inevitable, so it is crucial to be prepared. Many have underestimated infectious diseases, but they remain a significant threat.

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"There's the transformative, if I might use that word, experience that we've all had now in year five of COVID." The speaker says, "The thought that we won't have another pandemic, I think is naive at best and just not completely unrealistic at worst." They add, "I'm convinced that there will be another pandemic and that's the reason why we have to be perpetually prepared to prevent the terrible impact of a pandemic."

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Could the next pandemic surpass the severity of COVID-19? Experts warn that a new threat, referred to as Disease X, is likely to emerge. Dr. Peter Hotez, dean of the National School of Tropical Medicine, emphasizes the need for the U.S. to commit to better pandemic preparedness. He notes that while the next pandemic may not be as severe as COVID-19, it could still pose significant risks. The rise in pandemics is attributed to various factors, including climate change, which affects animal migration and the transmission of viral pathogens. Although the timing of Disease X remains uncertain, scientists agree that it is inevitable. More funding is needed for diagnostics, vaccines, and supporting researchers studying these threats.

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There will be another pandemic; it's just a matter of time. The annual risk is around 2% to 3%, and we must prepare for future outbreaks, including unexpected ones, often referred to as "black swans." The work we do now is crucial for readiness, as we will inevitably face new challenges and different types of viruses. It's essential to acknowledge that surprises will arise, and we need to be equipped to handle them.

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We must remain vigilant about current diseases, but an even greater danger is focusing too much on the last pandemic when preparing for future threats. Emerging infections can arise from various sources, and we are still vulnerable to intentional spread by those seeking to cause harm. Our global community's health faces numerous potential threats. It's crucial to consider a wide range of possibilities to effectively safeguard public health.

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We need to address the need for a fundamental change in our world. This process will take time, but once we have gone through it, the world will be different.

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I'm not a scientist, so I can't discuss vaccination, but there will be more pandemics in the future due to climate impacts and the emergence of new bacteria caused by greenhouse gases and methane emissions. We lack immunity to these new bacteria. COVID-19 is just one example of a pandemic, and it will continue to affect us.

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Experts are predicting that the next pandemic, known as disease X, could be even worse than COVID-19. Dr. Peter Hotez, an internationally recognized expert, believes that new pandemic threats will continue to rise regularly. He compares COVID-19 to a warm-up act for the next pandemic, which may not be as severe but could be more challenging. Previous pandemics like SARS, H1N1, Ebola, and Zika have already occurred. Dr. Hotez emphasizes the importance of pandemic preparedness, including funding for diagnostics, vaccines, and support for scientists studying these pathogens. Climate change is identified as a significant factor in the increase of pandemics. While the timing of disease X is uncertain, scientists agree that it is inevitable.

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There is a consensus that appears in the World Health Organization’s ten-year plan, which has been in place for a long time. The plan states that people should prepare for the coming ten years because a major infectious crisis is anticipated. In other words, the plan foretells that over the next decade there will be a significant infectious-health emergency. The speaker notes that “this was year 1,” indicating that the current year is the first year of that ten-year horizon outlined by the plan.

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In this exchange, the speakers reference the World Health Organization’s ten-year plan. The first speaker states that the plan has long warned: “for the coming 10 years, there will be a large infectious disease crisis,” and notes that “this was year 1.” The second speaker adds that the aim is to prepare and help, should a second pandemic occur, and asserts that, based on years of the speakers’ discussions, “the chance that a second pandemic comes is very large.” The first speaker reiterates that there is consensus and that the plan has anticipated a major infectious disease crisis over the decade, emphasizing that the warning has been a longstanding part of the plan.

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The UN general assembly adopted a declaration on pandemic prevention, preparedness, and response. The COVID-19 pandemic disrupted societies and economies, exposed political fault lines, eroded trust, and highlighted inequalities. The next pandemic is inevitable, so WHO member states are negotiating a new pandemic accord and amendments to strengthen the global response. National ratification and accountable implementation are crucial to avoid repeating past mistakes. We must not return to the cycle of panic and neglect. Our world needs to be stronger for future generations.

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In the future, there may be a deadly airborne disease. To effectively deal with it, we need to establish a global infrastructure that enables us to quickly detect, isolate, and respond to such outbreaks. By investing in this infrastructure now, we can be better prepared for future strains of flu, like the Spanish flu, that may emerge in the next five to ten years. It is a wise investment to make.

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We must support 40 countries to govern themselves to be prepared for future pandemics. Communication and disinformation are critical issues. Media must fulfill their responsibilities and science should guide decision-making. Top scientists should provide expertise to society through scientific institutions.

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We should not return to our complacency about pandemics. In the future, we can have mega testing platforms that are quick, inexpensive, and can test 20% of the population weekly. Monoclonal antibodies are a promising treatment that can reduce death rates by 80%. The development of new vaccines will be faster, easier, and cheaper thanks to the mRNA platform. To prevent future pandemics, we need a global alert system and a group of infectious disease responders who can act quickly. This investment is like the best insurance policy the world could buy.

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If a highly infectious virus is to cause over 10 million deaths in the coming decades, it is likely due to a pandemic. Without proper preparedness, a new airborne outbreak could significantly impact millions. Future administrations will inevitably face challenges similar to those of their predecessors, making pandemic prevention a top priority. The current administration will confront its first major epidemic, potentially influenced by impulsive and fact-averse attitudes. The likelihood of another severe pandemic is high, as seen with the emergence of a new coronavirus. There is a possibility of a novel avian virus outbreak, which could lead to rapid vaccine development and self-administration.

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In the future, there might be a deadly airborne disease. To effectively handle it, we need a global infrastructure that enables us to detect, isolate, and respond to it swiftly. This infrastructure should be in place not only in our country but worldwide. By investing in this infrastructure, we can be better prepared to tackle future outbreaks, such as a new strain of flu similar to the Spanish flu, that may emerge in the next five or ten years.

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I will discuss pandemic preparedness today. Based on my experience, I can say that the next administration will face challenges with chronic infectious diseases and unexpected outbreaks. In my 32 years as NIAID director, history shows that these challenges are inevitable for the new administration.

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The pandemic agreement is crucial for humanity to prevent future suffering from pandemics. Young people must advocate for this agreement to protect future generations. It is essential to counter misinformation that undermines the agreement. Ultimately, the pandemic agreement is about securing a better future for all.

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We need to actively work to prevent the predicted outcome of this virus. It's important for each individual to get involved and determine the truth for themselves. We shouldn't blindly accept everything we're told by so-called experts. We should engage with our community, representatives, and leaders to find a solution. I believe there is a solution, and it requires a comprehensive and urgent approach from the entire world.

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As a kid, nuclear war was the big fear. Now, a highly infectious virus is the greatest global catastrophe risk. An epidemic, whether natural or intentional, is the most likely cause of over ten million deaths in the coming decades. We are not ready for the next epidemic, and it's surprising how little preparedness there is. To prepare, we need to run simulations, like germ games instead of war games, to identify our weaknesses. If we start now, we can be ready.

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The UN General Assembly adopted a declaration on pandemic prevention, preparedness, and response. The COVID-19 pandemic disrupted societies and economies, exposed political fault lines, and eroded trust. The next pandemic is inevitable, so WHO member states are negotiating a new pandemic accord and amendments to strengthen the global response. National ratification and accountable implementation are crucial to avoid repeating past mistakes. We must not return to the cycle of panic and neglect. Together, we are stronger.
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