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Dr. Albert Bourla, Pfizer's chairman and CEO, is recognized for his significant impact on global COVID-19 response efforts. As a child of Holocaust survivors, Bourla led his team to develop a COVID-19 vaccine in record time, declining US federal funding to avoid bureaucracy and accelerate production. He is proud of his Jewish heritage, active in Holocaust remembrance, and a strong supporter of Israel, which was the first country outside the US to receive the Pfizer vaccine and antiviral pill. With over 2.5 billion Pfizer vaccine doses distributed, Bourla is credited with helping to save lives during the pandemic. For his contributions, Dr. Bourla has been selected as the recipient of the 2022 Genesis Prize, also known as the "Jewish Nobel Prize."

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We are making this dream a reality with this announcement. The COVID vaccine has proven to be highly effective, although its logistics were complex due to the new technology.

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They have discovered a potential breakthrough in cancer treatment using mRNA technology similar to COVID vaccines. By biopsying a patient's cancer, extracting its protein, and reintroducing it into the patient's cells, they have successfully treated 10,009 people in clinical trials, all of whom are now cancer-free. This method shows promise in curing cancer. Translation: A breakthrough in cancer treatment has been found using mRNA technology. By using a patient's cancer protein, they have treated 10,009 people who are now cancer-free, showing potential in curing cancer.

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Dr. Kizzmekia Corbett and her team have been studying spike proteins in viruses for the past 10 years. They discovered that controlling the spike protein's shape is crucial for creating effective vaccines. Using their knowledge from previous research on MERS coronavirus, they quickly applied their techniques to develop a vaccine for the current virus in collaboration with Moderna. By January 10th last year, they obtained the virus sequences and produced the vaccine over the weekend. They tested the vaccine on mice and found that it generated antibodies. Dr. Corbett mentions that they are now working on addressing the variants of the virus.

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mRNA vaccines, like the ones developed for the pandemic, have brought attention to the potential of gene and cell therapy. Previously, if we had asked the public if they would be willing to receive such treatments, the majority would have refused. However, the pandemic has changed people's perspectives and made them more open to innovative approaches in healthcare.

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mRNA vaccines have shown the potential of cell and gene therapy. Two years ago, most people would have refused gene or cell therapy, but the pandemic has increased acceptance of innovative treatments.

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In the fight against COVID-19, Pfizer CEO Dr. Albert Bourla, a child of Holocaust survivors, played a key role in developing the vaccine. His Jewish heritage and support for Israel are notable. Over 2.5 billion Pfizer vaccine doses have been distributed worldwide. For his contributions, Dr. Bourla received the 2022 Genesis Prize, known as the Jewish Nobel Prize. The pandemic continues, but Dr. Bourla's efforts have made a significant impact in saving lives globally.

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Our company is embracing cell and gene therapy, which has the potential to make a significant impact. The mRNA vaccines are a prime example of this. Just a couple of years ago, if we had asked the public if they would be willing to undergo gene or cell therapy, the majority would have refused. However, the pandemic has changed people's perspectives and made them more open to innovative solutions.

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Today, Doctor Katalin Kariko and Doctor Drew Weissmann were awarded the Nobel Prize in Physiology or Medicine for their groundbreaking work in creating mRNA vaccines for COVID-19. This achievement marks a significant milestone in the field of health and science. The development of safe and effective vaccines has played a crucial role in combating the pandemic and bringing it under control. Congratulations to both doctors on this well-deserved recognition.

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The Food and Drug Administration granted final approval to the Pfizer COVID vaccine. Those hesitant due to its Emergency Use Authorization may now be more inclined to take it. The vaccine has been proven safe and effective and now has final approval. The speaker urges listeners to take the vaccine to save their life, and potentially the life of another.

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I'm here to receive the SARS 2 vaccine as a scientist working on Coronaviruses. Vaccines have saved countless lives worldwide, and it's crucial for me to volunteer and build confidence in this approach. I hope other scientists, political figures, and media personalities will also step up and take these vaccines to save lives.

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That extraordinary person is Pfizer Chairman and CEO, Doctor. Albert Borla. Doctor Borla led his team to deliver a COVID nineteen vaccine in record time while taking a risk by declining US federal funding to avoid government bureaucracy and expedite vaccine production. A child of Holocaust survivors from a Greek Jewish community destroyed by the Nazis, he's proud of his Jewish heritage, is active in Holocaust remembrance and education, and a strong supporter of Israel, which was the first country outside The US to receive the Pfizer vaccine and the antiviral pill. With more than two and a half billion Pfizer vaccine doses already distributed. Because of Doctor. Borla's extraordinary contribution to humanity as the world battles the worst health crisis in January, Doctor Albert Borla has been selected as the recipient of the 2022 Genesis Prize, the Jewish Nobel Prize. Thank you, and congratulations, Doctor. Borla.

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Two years ago, most people would have refused gene or cell therapy, but the pandemic has changed that. mRNA vaccines are a prime example of this shift towards innovation in healthcare.

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We are working on developing new vaccines like TB and HIV using mRNA technology to make them high quality and low cost. Current COVID vaccines are not perfect, so we are working on new versions with longer-lasting protection for diseases like measles and tuberculosis. The mRNA technology also shows promise for cancer vaccines and rapid adaptation to future pandemics. We are even exploring using this technology for animal vaccines.

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In the global fight against COVID-19, the Jewish people have had an outsized impact. As scientists, chief medical officers, and top healthcare officials, their contributions have been invaluable. However, one person stands above the rest: Pfizer Chairman and CEO, Dr. Albert Borla. I led my team to deliver a COVID-19 vaccine in record time, declining US federal funding to avoid bureaucracy and expedite production. As a child of Holocaust survivors, I am proud of my Jewish heritage and a strong supporter of Israel, the first country outside the US to receive the Pfizer vaccine and antiviral pill. The world is better off with my leadership in saving lives. With over 2.5 billion Pfizer vaccine doses distributed, I am honored to be selected as the recipient of the 2022 Genesis Prize, the Jewish Nobel Prize, for my contribution to humanity during the worst health crisis in a century.

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Professor Sarah Gilbert, Doctor Catherine Green, and the Oxford team are honored for their groundbreaking research on the Oxford vaccine, which has greatly contributed to the fight against COVID-19. Their humanitarian approach led them to send research cultures to India early on, showcasing the biotech collaboration needed to end the global crisis. However, vaccine equity remains a challenge, with less than 2% of people in the Developing World receiving a single dose. Additionally, the spread of misinformation on news and social media is fueling vaccine hesitancy and eroding trust. Overcoming these obstacles is crucial to defeating COVID-19 and preventing new variants. The Oxford team has played their part.

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I've been involved in over 50 vaccines, including mRNA vaccines. mRNA is like DNA, giving cells instructions to make proteins. This technology was originally for gene therapy, now used for vaccines. It's a new, experimental technology never used in humans before COVID. Animal studies were skipped for COVID vaccines, a novel approach.

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We are working on developing new vaccines for diseases like TB, HIV using mRNA technology. The goal is to create high-quality, low-cost vaccines that can be used for various illnesses. Current COVID vaccines have limitations, so we are working on next-generation vaccines with longer-lasting protection. mRNA technology also shows promise for cancer vaccines and potential future pandemics. Additionally, we are exploring using this technology for animal vaccines.

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Professors William Campbell, Satoshi Omura, and Tu You You were awarded the Nobel Prize for their groundbreaking discoveries in medicine. Their work has revolutionized the treatment of parasitic diseases and improved the well-being of individuals and society. Professor Campbell, a US citizen, is accompanied by his wife, daughters, and other family members. Professor Omura, a Japanese citizen, is joined by his daughter, brother, sister, and other relatives. Professor Tu You You, from China, is accompanied by her husband and two daughters. Their contributions have had an immeasurable global impact, and they are being honored with the Nobel Prize by His Majesty, the King.

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We are in a digital and scientific revolution, hacking the software of life with mRNA. Our body is made of organs, organs of cells, and in each cell is messenger RNA transmitting DNA information to proteins. This "operating system" can be altered to impact diseases like the flu and cancer. For instance, instead of injecting virus proteins for a flu vaccine, mRNA instructions can teach the body to make its own protection. This mRNA technology has vast potential for disease prevention and treatment.

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Using mRNA technology similar to that used for COVID, researchers are taking biopsies of a patient's cancer, extracting protein, and reintroducing it into the patient's cells. In clinical trials, 10,009 humans have been treated. All 10,009 are now cancer free. The researchers claim to have cured cancer.

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Our company is embracing cell and gene therapy, which has the potential to make a significant impact. mRNA vaccines are an example of this type of therapy. Two years ago, if we had asked the public if they would be willing to undergo gene or cell therapy, the refusal rate would have been around 95%. However, the pandemic has made people more open to innovation in ways that were previously unimaginable.

TED

How mRNA Medicine Will Change the World | Melissa J. Moore | TED
Guests: Melissa J. Moore
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Messenger RNA (mRNA) vaccines are safe and effective, providing instructions for the body to protect against SARS-CoV-2. mRNA technology is revolutionizing medicine, enabling treatments for previously untreatable disorders by instructing the body to produce necessary proteins. Each of the 30 trillion cells in the body contains billions of proteins, essential for various functions. Current clinical trials are exploring mRNA applications for metabolic diseases, personalized cancer vaccines, and regenerative medicine. The rapid production capabilities of mRNA allow for quick responses to emerging diseases, with potential for combination vaccines targeting multiple viruses.

Into The Impossible

The mRNA Breakthrough That Changed Medicine Forever with Nobel Laureate Katalin Karikó [Ep. 464]
Guests: Katalin Karikó
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In this episode of the Into the Impossible podcast, host Brian Keating interviews Nobel laureate Katalin Karikó, who won the 2023 Nobel Prize in medicine for her pivotal role in developing the COVID-19 vaccine. Karikó discusses her background, including her humble beginnings in Hungary and her journey as a scientist. She emphasizes the importance of curiosity and perseverance in scientific research, stating that her motivation stemmed from a passion for science rather than prestige. Karikó shares insights from her autobiography, "Breaking Through: My Life in Science," detailing her experiences and the challenges she faced, including working under a communist regime and overcoming skepticism about her research. She highlights the significance of RNA, particularly mRNA, in vaccine development, explaining how her collaboration with Drew Weissman led to breakthroughs that made the COVID-19 vaccine possible. The conversation also touches on the public's perception of vaccines, the importance of educating society about science, and the need for collaboration in research. Karikó reflects on her career, the obstacles she overcame, and the collective effort behind the vaccine's success. She encourages future generations to remain curious, honest, and resilient in their pursuits, emphasizing that the journey of a scientist is about helping others and contributing to humanity.

TED

Uğur Şahin and Özlem Türeci: Meet the scientist couple driving an mRNA vaccine revolution | TED
Guests: Uğur Şahin, Özlem Türeci, Chris Anderson
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Uğur Şahin and Özlem Türeci reflect on their journey in developing mRNA technology, which began two decades ago with a focus on using the immune system to combat cancer. They founded BioNTech to expedite bringing scientific advancements to patients. The urgency of the COVID-19 pandemic in early 2020 prompted them to pivot their technology for vaccine development, leading to a highly effective mRNA vaccine against the virus. They emphasize the potential of mRNA beyond infectious diseases, particularly in personalized cancer therapies. Their success has transformed BioNTech, enabling broader innovations in medicine. They also highlight the importance of diversity in their team, showcasing how globalization enhances scientific collaboration.
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