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The speakers claim gain of function research creates dangerous viruses to develop protections against them. They allege that in 2015, a London meeting identified the Wuhan lab as likely to have problems with this research, and that Anthony Fauci was a major supporter of gain of function research for 30 years.
One speaker claims gain of function research takes a wild virus and makes it more pathogenic, virulent, and deadly to develop a vaccine, suggesting the rationale is to develop bioweapons and defenses. They allege Fauci received a 68% raise from the military for these responsibilities.
They claim that after three lab escapes in 2014, 300 scientists asked President Obama to shut down Fauci's gain of function research, warning it could start a global pandemic. Obama issued a moratorium, but instead of shutting down the research, it was allegedly moved offshore to places like Ukraine, Georgia, and the Wuhan Institute of Virology, which is run by the Chinese military.