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The threat of smallpox as a weapon of terror has resurfaced, with evidence suggesting that Soviet scientists who weaponized it during the Cold War may be working elsewhere. Smallpox is highly infectious and can spread through the air, potentially infecting and killing a large number of people. However, there is a lack of vaccine supply in the United States, with only 15 million doses available. Congress aims to produce an additional 200 million doses, but the necessary legislation has not been sent to the president yet. A French company recently discovered over 70 million doses of smallpox vaccine in its freezers. Research shows that the existing vaccine can be diluted and still provide adequate protection, potentially stretching the supply to 150 million doses. The question now is who will receive the vaccine and when, as the consequences of a bioterror attack with smallpox could be devastating, resulting in estimates of 100,000 to 1 million deaths.

Today, almost any country can create a powerful biological weapon in a couple of months using current technology.

The discussion centers on gain-of-function (GoF) research, its regulation, and the motivations behind it. The first speaker notes the administration’s goal to end GoF research and asks where that stands. The second speaker says progress has been made, and the White House is working on a formal policy. He then defines the issue in stages: what GoF research is, why someone would do it, and how to regulate it to prevent dangerous projects that could catastrophically harm human populations. He clarifies that GoF research is not inherently bad, but dangerous GoF research is. He gives an insulin example: creating bacteria to produce insulin is a legitimate GoF that benefits diabetics. In contrast, taking a virus from bat caves, bringing it to a lab in a densely populated city with weak biosafety, and manipulating it to be more transmissible among humans is a dangerous GoF that should not be supported. The administration’s policy aims to prevent such dangerous work entirely, and the President signed an executive order in April or May endorsing this policy. Next, he discusses implementation: how to create incentives to ensure this research does not recur. He explains that the utopian idea behind such research was to prevent all pandemics by collecting viruses from wild places, testing their potential to infect humans by increasing their pathogenicity, and then preparing countermeasures in advance (vaccines, antivirals) and stockpiling them, even though those countermeasures would not have been tested against humans yet. If a virus did leap to humans, the foreseen countermeasures might prove ineffective because evolution is unpredictable. This “triage” approach—identifying pathogens most likely to leap and preemptively preparing against them—was the rationale for dangerous GoF work, a rationale he characterizes as flawed. He notes that many scientists considered this an effort to do bioweapons research under the guise of safety and defense. The work is dual-use. The U.S. is a signatory to the Biological Weapons Convention and does not conduct offensive bio-weapons research, but other countries might. The discussion highlights that the GoF research discussed during the pandemic can backfire and may not align with true biodefense, since countermeasures might not match whatever pathogen actually emerges. The speaker concludes that this agenda—pursuing GoF to prevent pandemics—has drawn substantial support from parts of the Western world and other countries for about two and a half decades, but he implies it is not deserving of continuation.

There are 25 to 30 US-funded biolabs in Ukraine researching dangerous pathogens. As Ukraine is an active war zone, these labs could be compromised, releasing deadly pathogens that know no borders. To protect people worldwide, these labs must be shut down immediately, and their pathogens destroyed. The Biden-Harris administration should work with Russia, Ukraine, NATO, and the UN to implement a ceasefire near these labs until they're secured and the pathogens are destroyed. The US funds around 300 biolabs globally, some engaging in risky gain-of-function research, similar to the Wuhan lab. These labs should have been shut down two years ago. This isn't a partisan issue; the administration and Congress must act now for global health and well-being.

The perception, not reality, leads to the killing of bio-threat defense projects. 50% of allies believe the US has an offensive bioweapons program, which is false. Since Nixon, there has been no such program. Developing countermeasures against bio-threats can be mistaken for an offensive program, causing public and political concerns. The information will be published in Science and Nature soon.

The new global health security strategy aims to enhance capabilities to combat various health threats worldwide. It focuses on strengthening capacities through partnerships, mobilizing political support and financing, and fortifying global defenses. The strategy emphasizes the importance of investing in prevention, early detection, and response to outbreaks to protect lives and economies. Collaboration with partners, including governments and organizations, is crucial for effective global preparedness. The strategy also highlights the need for sustainable investments in technologies and manufacturing to ensure readiness for future health crises. The strategy underscores the significance of bipartisan support and partnership with Congress to address health security challenges effectively. Translation: The new global health security strategy aims to enhance capabilities to combat various health threats worldwide. It focuses on strengthening capacities through partnerships, mobilizing political support and financing, and fortifying global defenses. The strategy emphasizes the importance of investing in prevention, early detection, and response to outbreaks to protect lives and economies. Collaboration with partners, including governments and organizations, is crucial for effective global preparedness. The strategy also highlights the need for sustainable investments in technologies and manufacturing to ensure readiness for future health crises. The strategy underscores the significance of bipartisan support and partnership with Congress to address health security challenges effectively.

President Bush has decided to offer the smallpox vaccine to millions of Americans due to fears of terrorism. The vaccine, although effective, has serious side effects and can be deadly. Smallpox is a deadly disease that kills one out of every three victims and was eradicated in 1980. The vaccine is made from a weaker version of the virus and can cause severe reactions. Some experts believe that vaccinating only a few people until there is an outbreak is a safer approach. However, others argue that smallpox is a serious threat and should be taken seriously. The government plans to vaccinate medical personnel and emergency workers first, with the general public later on.

The speaker discusses the current state of biodefense and the need for a different approach due to emerging threats and advancements in technology. They highlight the importance of collaboration and the removal of bureaucratic barriers in addressing these challenges. The speaker also mentions the development of nonspecific medical countermeasures to enhance the immune system's response to unknown agents, as well as the rapid advancement of specific drugs through computational systems. They emphasize the role of situational awareness and the vulnerabilities in the industrial base and supply chain. The speaker concludes by discussing the review of policies, strategies, operational posture, research and development pipeline, and total force readiness in biodefense.

There are 25 to 30 US-funded biolabs in Ukraine conducting research on dangerous pathogens. Given the ongoing war, these facilities are at risk of being compromised, potentially leading to the spread of deadly pathogens across Europe and beyond. To protect global health, these labs must be shut down immediately, and the pathogens destroyed. The Biden administration should collaborate with Russia, Ukraine, NATO, and the UN to establish a ceasefire around these labs until they are secured. Additionally, the US funds approximately 300 biolabs worldwide that are also engaged in similar research.

To create a defensive program against bioterrorism, the speaker consulted with unconventional sources. These included former U.S. bioweapons experts from decades ago, international figures from countries like the U.K., and defectors from the Soviet Union. The speaker learned from these experts to inform the development of a multi-billion dollar program.

There are 25 to 30 US-funded biolabs in Ukraine conducting research on dangerous pathogens in an active war zone. The risk of these labs being compromised is high, which could lead to the spread of deadly pathogens across Europe and the world. To protect global health, these labs should be shut down immediately, and their pathogens destroyed. The Biden administration should collaborate with Russia, Ukraine, NATO, and the UN to establish a ceasefire around these facilities until they are secured. Additionally, the US funds around 300 biolabs worldwide engaged in similar risky research. Given the potential dangers, these labs should have been closed two years ago. This issue transcends partisan politics; immediate action is necessary for the safety of all people.

There are 25 to 30 US-funded bio labs in Ukraine researching dangerous pathogens, according to the US government. Because Ukraine is an active war zone, these labs could be compromised, releasing deadly pathogens that know no borders. If breached, these pathogens could spread throughout Europe, the United States, and the rest of the world, causing suffering and death. To protect people, these labs need to be shut down immediately, and the pathogens they hold need to be destroyed. The Biden-Harris administration needs to work with Russia, Ukraine, NATO, and the UN to implement a ceasefire for military action near these labs until they are secured and the pathogens destroyed. The US funds around 300 bio labs around the world.

There are 25 to 30 US-funded bio labs in Ukraine researching dangerous pathogens. Because Ukraine is an active war zone, these labs could be compromised, releasing deadly pathogens that know no borders. If breached, these pathogens could spread throughout Europe, the United States, and the rest of the world, causing suffering and death. To protect people, these labs need to be shut down immediately, and the pathogens they hold need to be destroyed. The Biden-Harris administration needs to work with Russia, Ukraine, NATO, and the UN to implement a ceasefire for military action near these labs until they are secured and the pathogens are destroyed. The US also funds around 300 bio labs around the world.

There is a concern about the potential for a big war or a natural pandemic, which could cause millions of deaths. The last major pandemic happened a century ago, but with the speed of global travel, the spread of diseases is faster now. However, the speaker is more worried about bioterrorism. They mention that even a small terrorist group could cause significant damage using non-human to human transmissible agents like anthrax. Thankfully, these groups have not yet been able to acquire nuclear weapons.

In the future, there may be a deadly airborne disease. To effectively deal with it, we need to establish a global infrastructure that enables us to quickly detect, isolate, and respond to such outbreaks. By investing in this infrastructure now, we can be better prepared for future strains of flu, like the Spanish flu, that may emerge in the next five to ten years. It is a wise investment to make.

In the future, there might be a deadly airborne disease. To effectively handle it, we need a global infrastructure that enables us to detect, isolate, and respond to it swiftly. This infrastructure should be in place not only in our country but worldwide. By investing in this infrastructure, we can be better prepared to tackle future outbreaks, such as a new strain of flu similar to the Spanish flu, that may emerge in the next five or ten years.

The speaker discusses the importance of the Bioposture Review (BPR) and the need for active US government engagement in biodefense. They mention the appointment of new leadership, the creation of a Biodefense Council, and the need for better biosafety and biosecurity. The BPR addresses bio threats from various sources, including natural, man-made, and accidental, and emphasizes the importance of international cooperation. The speaker also highlights the role of the Department of Defense (DoD) in supporting civilian efforts during the COVID-19 pandemic and other bio threats. They mention the need for ongoing reviews and the establishment of working groups to address policy and strategy challenges in biodefense. The speaker concludes by discussing the funding request for biodefense initiatives.

There are 25 to 30 U.S. funded biolabs in Ukraine conducting research on dangerous pathogens. These labs could easily be compromised due to the ongoing war in the region, potentially releasing deadly pathogens that could spread worldwide. To protect people, these labs should be shut down immediately and the pathogens destroyed. The Biden Harris administration should collaborate with Russia, Ukraine, NATO, and the UN to implement a ceasefire in the vicinity of these labs. Additionally, the U.S. funds around 300 biolabs worldwide, engaging in risky research similar to the Wuhan lab. These labs should have been closed two years ago. It is crucial for the administration and Congress to take action for the well-being of everyone.

There is a concern about the potential for a big war or a natural pandemic, which could cause millions of deaths. The last major pandemic happened a century ago, but with the speed of global travel, the spread of a pandemic could happen quickly. However, the speaker is most worried about bioterrorism. They believe that even a small terrorist group could cause significant harm using non-human to human transmissible agents like anthrax. Thankfully, these groups have not yet been able to obtain or create a nuclear weapon.

There are 25 to 30 US-funded bio labs in Ukraine researching dangerous pathogens. Because Ukraine is an active war zone, these labs could be compromised and release deadly pathogens that know no borders. If breached, these pathogens will spread throughout Europe, the United States, and the rest of the world, causing suffering and death. To protect people, these labs need to be shut down immediately, and the pathogens they hold need to be destroyed. The Biden-Harris administration needs to work with Russia, Ukraine, NATO, and the UN to implement a ceasefire until the labs are secured and the pathogens destroyed. The US funds around 300 bio labs around the world engaging in dangerous research, including gain of function. These labs should have been shut down two years ago. The administration and congress need to act now for the health and well-being of every person on this planet.

There are 25 to 30 US-funded biolabs in Ukraine conducting research on dangerous pathogens amid an active war. These facilities are at risk of being compromised, potentially leading to the spread of deadly pathogens worldwide, similar to COVID-19. To protect global health, these labs must be shut down immediately, and the pathogens destroyed. The Biden administration should collaborate with Russia, Ukraine, NATO, and the UN to establish a ceasefire around these labs until they are secured. Additionally, the US funds around 300 biolabs globally engaged in risky research. Given the vulnerabilities of these labs, they should have been shut down two years ago. This issue transcends partisan politics; immediate action is necessary for the safety of all people.

The transcript covers a broad set of interwoven claims about global health security, intelligence operations, political conspiracies, and alleged CIA influence on U.S. leadership. Key points include: - Pandemic preparedness and global infrastructure: There is discussion that an airborne, deadly disease could emerge, and to deal with it effectively we must put in place infrastructure globally and domestically to see, isolate, and respond quickly. The investment is framed as a smart, long-term insurance against future flu strains like the Spanish flu, especially in a globalized world. - CIA and presidency dynamics: The day after an election, the CIA director allegedly authorizes a president-elect to begin receiving a President’s Daily Brief (PDB) and uses the briefing to “suck him in,” presenting impressive can-dos that shape the new president’s perceptions and questions. This is described as psychological profiling and manipulation, with the CIA using long-standing methods to influence a president and government direction. - Allegations of a covert cabal influencing U.S. institutions: The conversation suggests a cabal has aimed to destroy U.S. institutions from within, including defunding the military and ordering actions that undermine allies while aiding enemies. This cabal allegedly includes control over the FBI, DOJ, and the presidency, culminated in the appointment of James Comey to head the FBI, portrayed as a “cardinal” with ties to the Clinton Foundation and as part of broader cabal activity. - 2008–2011 FBI and political corruption narrative: An asset described as a high-level foreign agent allegedly influenced U.S. politics and was connected to multiple intelligence services, with claims about his role in internal U.S. political manipulation. The rise of a president referred to as “Renegade,” identified as Barry Sartaro (Barry Soetoro), is described as part of the cabal’s plan to destabilize the United States from within, including military demoralization and misdirection. - Barack Obama conspiracy theories: The dialogue asserts that Barack Obama’s origins and identity have been manipulated for political purposes, including claims about a forged birth certificate, ongoing questions about birth location, and various individuals connected to Hawaii’s health department and local authorities providing or denying birth certificate verification. References include Loretta Fuddy and investigations into Obama’s birth details, with assertions that Obama’s name and identity were manipulated in Indonesia (Barry Soetoro) and that his family connections tie to CIA-backed operations in Asia. - Indonesia coup and CIA involvement: The conversation links Obama’s family to CIA-backed activities in Indonesia, including the overthrow of Sukarno and the rise of Suharto, with relatives described as having roles in money channels and death squads. The narrative asserts that Lolo Soetoro acted in intelligence-adjacent roles and that Obama’s grandmother helped channel CIA funds in the region. - Claims about CIA media manipulation and “MK Ultra” style operations: The speakers reference Operation Mockingbird, MK Ultra, and other CIA operations as public knowledge used to undermine the American people. They suggest continued silencing and manipulation by those operations. - Kill lists and drone warfare under the Obama administration: The transcript alleges that John Brennan led “Tuesday morning kill list” meetings starting in 2009, with drones and targeted killings used to eliminate designated individuals, and asserts confidence that Obama’s administration excelled at deploying missile strikes and other covert actions, contrasted with the possibility of ongoing use by subsequent administrations. - Recurrent thread of distrust in institutions: Across pandemic planning, birth certificate controversy, foreign influence, CIA cabal theories, and drone warfare, the overarching theme is distrust of established institutions and assertion of deep, planned manipulation by covert actors.

The speaker discusses the importance of biodefense and the need to prioritize it beyond just the context of COVID-19. They highlight the need to prevent the acquisition of dangerous pathogens and maintain the capability to control outbreaks in the event of a biological attack. The speaker mentions the inaugural biodefense posture review and efforts to align with the national defense strategy. They emphasize the need for collaboration and integration across departments, agencies, and allies. The speaker also discusses the evolving threat landscape, the importance of biosurveillance, and the concept of integrated layered defense. They mention the development of non-specific medical countermeasures and advancements in drug development. The speaker concludes by emphasizing the need for cohesion, coordination, and collaboration within the biodefense community.

In preparation for a new pandemic, the United States has begun searching for and applying various technologies for global management purposes. This includes creating crisis situations of a global nature.

I propose project Bio Shield, a research and production effort to protect against bioterrorism. My budget allocates nearly $6 billion for vaccines and treatments against anthrax, botulinum toxin, Ebola, and plague. We cannot wait for these diseases to become weapons; we must act now to safeguard our people.