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Host: They found that some of the longest living humans had high cholesterol levels.
Guest: That’s right. The Sweden study found, for example, a year or so ago, that among the most consistent themes were good glucose control and high cholesterol. I’m a defender of cholesterol. It is a molecule of life; mitochondria have to have a cholesterol molecule in them to work, the powerhouse of the cell. The more you lower cholesterol through drug interventions, the more you compromise the mitochondria. The sex hormones—all sex hormones—are built on cholesterol, so lowering cholesterol can lead to lower sex hormones and, for some men, loss of libido due to lower testosterone, owing to the war on cholesterol.
Host: But there’s good and bad cholesterol, right?
Guest: Well, that’s the common view, but LDL cholesterol is not simply “bad.” LDL is included in longevity studies and plays a role in the immune system; LDL helps the body fight infections, acting as an unsung hero of immunity.
Host: There is research suggesting that in very old age, high cholesterol levels do not always correlate with higher mortality, and in some studies may even be linked to longer life.