reSee.it Podcast Summary
In this podcast episode, Peter Attia and Sean Mackey discuss the complexities of pain, its definitions, and the evolving understanding of pain management. Mackey emphasizes that consciousness is necessary for the experience of pain, countering the misconception that unconscious patients do not feel pain. He highlights the historical dualistic model of pain, which separates the mind and body, as outdated and argues for a biopsychosocial model that integrates physical, emotional, and social factors.
Mackey acknowledges the opioid crisis, stating he is neither pro-opioid nor anti-opioid but pro-patient. He discusses the overprescription of opioids and the societal pressures that contributed to the crisis, while also recognizing the benefits of opioids in certain contexts, particularly for end-of-life care. He stresses the importance of understanding individual patient histories, including factors like early life experiences, depression, and anxiety, which can influence pain perception and treatment outcomes.
The conversation also covers different types of pain, including nociceptive, neuropathic, and nociplastic pain, and the challenges in treating them. Mackey explains the role of various medications, including NSAIDs, acetaminophen, muscle relaxants, and antidepressants, in pain management. He highlights the potential of low-dose naltrexone (LDN) as a treatment for conditions like fibromyalgia and complex regional pain syndrome, noting its safety profile and the need for further research.
Mackey shares insights on the societal burden of chronic pain, which surpasses that of diabetes, heart disease, and cancer combined. He discusses the importance of addressing psychological factors in pain management and the need for a comprehensive approach that includes physical rehabilitation and emotional support.
Attia shares his personal experience with chronic pain and how it shaped his understanding of patient care. He emphasizes the significance of self-efficacy and knowledge in managing pain, illustrating how his journey has informed his practice as a physician. The episode concludes with a discussion on the importance of empathy in treating patients with chronic pain and the need for ongoing education and research in the field of pain management.