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Vitamin D3 is the only vitamin humans can make, and every cell has a receptor for it. As we age, vitamin D3 levels decrease, and when they remain in single digits, rheumatoid arthritis-like symptoms can occur. A doctor might diagnose rheumatoid arthritis based on symptoms alone and prescribe corticosteroids. The speaker claims that corticosteroids lead to joint replacements in about six years. The speaker alleges that this cascade begins with a vitamin D3 deficiency, leading to an incorrect diagnosis, unnecessary medication, and ultimately, an unneeded joint replacement. After the joint replacement, reduced mobility allegedly brings on diseases exacerbated by reduced movement, and mortality risk increases.

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Many people are vitamin D deficient, leading to increased risks of depression, Parkinson's, Alzheimer's, and cancer. Supplementing vitamin D alone won't help if you're eating poorly, not exercising, smoking, or drinking excessively. However, in an otherwise healthy lifestyle, correcting low vitamin D can make a big difference. It's important to consider context, as magnesium is crucial for converting vitamin D into its active form. About 50% of people don't get enough magnesium from sources like dark leafy greens, pumpkin seeds, dark chocolate, and almonds. Stress, coffee, alcohol, and sugar deplete magnesium levels. Magnesium is an anti-aging macro-mineral involved in DNA repair enzymes.

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We should have recommended nationwide vitamin D supplementation to fortify immune systems against severe disease. Vitamin D has been attacked by the pharmaceutical industry for threatening the disease model. They are terrified of it. If you fear vitamins, you're likely on the wrong side.

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The most crucial nutrient for the human body is vitamin D3, often deficient but easily fixed. Take at least 5,000 IUs of vitamin D3 with 120-140 micrograms of K2, preferably MK-7 for better absorption. This combination helps calcium go to the bones instead of the arteries, reducing risks of high blood pressure, heart disease, congestive heart failure, peripheral artery disease, stroke, and heart attack.

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Vitamin D3 supplementation is associated with a 40% reduced risk of dementia, likely by preventing deficiency. Studies involving dementia and Alzheimer's patients showed that vitamin D supplementation improved cognition and lowered markers of amyloid plaques compared to a placebo. Vitamin D regulates 5% of the protein coding human genome.

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Vitamin D alone could prevent about 30,000 cancer deaths in a single country in a single year. The study looked in Germany and examined what would happen if they administered wide-scale vitamin D to the 50 and older population. Based on the most recent meta-analyses of vitamin D and cancer, there is about a 13% reduction in cancer mortality, and that is extrapolated to an entire country, resulting in saving about 30,000 lives per year. A recent paper on vitamin D and cancer and its biological effects is highlighted: there are over 900 peer-reviewed recent papers finding that vitamin D, when raised to adequate levels, exhibits anticancer activity against literally basically every single cancer known, through vitamin D receptor signaling as well as tumor microenvironment control and immune modulation. This is described as very, very important as winter months approach, so ensuring adequate vitamin D intake is advised. The speaker notes that some of the most powerful cancer prevention tools are neither profitable nor novel, and vitamin D is very inexpensive, biologically active, and, according to randomized clinical trial evidence, saves lives at scale. The main question posed is why public health agencies are ignoring this.

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Vitamin D is important; take at least 10,000 IUs, but for chronic problems, take 20,000-40,000 IUs. When taking vitamin D3, take K2 simultaneously to prevent calcium buildup in the arteries. K2 drives calcium from the blood and joints back into the bone, protecting against hypercalcemia. The ratio is 10,000 IUs of vitamin D3 to 100 micrograms of K2. If increasing D3 to 20,000 IUs, then take 200 micrograms of K2.

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We should have recommended nationwide vitamin D supplementation to fortify immune systems and protect against severe disease. Vitamin D has been attacked by the pharmaceutical industry for threatening the disease model. They are terrified of it. If you are scared of vitamins, you are probably on the wrong side.

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Vitamin D3, a neurosteroid produced in the brain from sunlight, may protect against neurodegeneration. Every major brain area has vitamin D receptors, including those for memory and mood. Harvard studies are using high-dose vitamin D for depression. These receptors control over 900 genes related to brain health. Low vitamin D levels may increase cognitive decline risk by 290%. Research indicates optimal D3 levels protect against depression, dementia, and brain aging. The brain will take vitamin D from other tissues if levels are low. Have vitamin D levels tested, aiming for 75-100 ng/mL. Take 5,000-7,000 IU of D3 daily with vitamin K2 for optimal absorption and brain benefits.

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About 80% of people are deficient in vitamin D, which can lead to various health issues like depression, Parkinson's, Alzheimer's, and cancer. However, simply taking vitamin D supplements won't help if you have an unhealthy lifestyle. If you clean up your lifestyle and still have low vitamin D levels, it can make a big difference. It's important to note that even if you spend a lot of time in the sun or take vitamin D supplements, without adequate magnesium in your diet, the enzymes that convert vitamin D into its active form won't function properly. Unfortunately, 50% of the population doesn't consume enough magnesium, which can be found in dark leafy greens, pumpkin, dark chocolate, and almonds. Magnesium is crucial for DNA repair enzymes and has anti-aging properties.

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"The secret to antiaging? It shouldn't cost a billion dollars. It's the cheapest form of vitamin d." "Harvard backed randomized control trial, the gold standard when evaluating if something works, where over a thousand adults were followed for four years." "And what they showed is vitamin d three slowed telomere shortening, aka biological aging, by nearly three years." "We take two thousand to max four thousand IUs of vitamin d three a day." "But it's important that we marry this to vitamin k two so that that calcium ends up in our bones and not our arteries." "Last, magnesium, because your body cannot activate vitamin d three without it." "And the best part of this study, the authors had zero conflicts of interest. Nada, Zip, Zilch. Just pure science." "Let me know if you guys have any questions below."

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Vitamin D3 is described as the single most important nutrient in the human body, yet 50% of the world's population is clinically deficient. This deficiency is easily fixed with supplementation. It is recommended to supplement with a minimum of 5,000 IUs of vitamin D3 and 120-140 micrograms of K2, specifically the MK4 version, which is believed to be the most bioavailable. Vitamin D3 with K2 helps calcium deposit into the bone rather than the arterial wall. Vitamin D deficiency is claimed to be a risk factor for developing high blood pressure, heart disease, congestive heart failure, peripheral arterial disease, and may increase the incidence of stroke and heart attack.

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Vitamin D deficiency increases the risk of cancer, and taking vitamin D can prevent cancer. It is also effective for treating depression and important for the immune system. Big pharma dislikes vitamin D because it reduces the risk of many diseases. Studies on vitamin D are often designed to fail using low doses. Higher doses are recommended for those with chronic inflammation or autoimmune diseases. The sun is beneficial and avoiding it increases the risk of dying. Sunshine also prevents cancer, including melanoma. Spending about 30 minutes in the sun without sunscreen is recommended, as sunscreen may increase the risk of melanoma.

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Vitamin D should always be taken with vitamin K2. Vitamin D3 increases calcium absorption, potentially leading to high blood calcium levels, which can be problematic. Vitamin K2 directs calcium from the blood into the bone, preventing soft tissue calcification in areas like arteries and joints. The recommended ratio is 100 micrograms of vitamin K2 for every 10,000 IUs of vitamin D3.

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Samples taken from patients before the pandemic show that a high level of vitamin D does not protect against Covid-19. In fact, it increases the risk of hospitalization by two times and also tends to advance the risk of severe illness.

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A recent large-scale vitamin D study was published in the American Journal of Clinical Nutrition. It was a four-year study involving 25,000 adults across the United States, conducted by 140 researchers. The study found that people who took vitamin D3, compared with omega-3 (which has other positive studies but not with telomere length in this study), had telomere length preservation. This new study follows a Canadian study from two years earlier, conducted over ten years with about 12,000 participants, which showed that vitamin D could reduce the risk of dementia by about forty percent. The earlier study was so convincing to the speaker that close family members, including the speaker’s wife and mom, began taking vitamin D3 regularly after that study, due to the goal of reducing dementia risk. According to the speaker, the current study’s findings suggest that vitamin D3 can help prevent dementia and also help maintain or preserve telomere length significantly, “only aging a year and four years.” The speaker notes that they did not say telomere length was reversed; to their knowledge, there’s no way to extend telomeres once they have shortened, so preservation is emphasized as important. The speaker urges starting vitamin D3 early, highlighting the implications of preserving telomere length and potentially reducing dementia risk as compelling reasons to take vitamin D3 regularly. The comparison to omega-3 is acknowledged, but the focal points are telomere length preservation and dementia risk reduction associated with vitamin D supplementation.

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Vitamin D is crucial; take at least 10,000 IUs, or more (20,000-40,000 IUs) for chronic issues. When supplementing with Vitamin D3, it's important to take Vitamin K2 simultaneously, especially regularly, to prevent calcium buildup in the arteries. Vitamin K2 directs calcium from the blood and joints back into the bone, counteracting the hypercalcemia risk associated with Vitamin D toxicity. The recommended ratio is 10,000 IUs of Vitamin D3 to 100 micrograms of Vitamin K2.

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In a large longitudinal study, twenty-nine thousand five hundred and eighteen women were followed for twenty years to examine the health effects of sun exposure. The findings from this extensive cohort are presented as surprisingly provocative. First, the study concluded that avoiding sun exposure reduces life expectancy to the same extent as heavy smoking. This comparison underscores the potential importance of sun exposure for overall health and longevity, challenging common assumptions that minimizing sun would uniformly improve health outcomes. Second, the researchers initially hypothesized that greater sun exposure would lead to a higher risk of deadly skin cancer, specifically melanoma. However, the data did not show a strong link between sun exposure and melanoma. In other words, there was almost no correlation between the amount of sun exposure and the incidence of melanoma, the deadliest form of skin cancer, in this study’s findings. From the study’s results, it appears that moderate and frequent sun exposure may be beneficial for health, contradicting the idea that more sun exposure is inherently dangerous. The identified risk factors were limited to sunburn and excessive sun exposure, which were singled out as problematic rather than ordinary or moderate sunlight exposure. The overarching takeaway presented is that getting outside and obtaining sunshine can be advantageous for health, whereas guarding against sunburn and avoiding excessive sun exposure are the critical boundaries to observe. The speaker emphasizes the practical implication by repeating a straightforward recommendation: this is a friendly reminder to get outside and get some sunshine. Overall, the message hinges on two main points: the potential longevity benefits associated with sun exposure and the unexpectedly weak association between sun exposure and melanoma risk within this large cohort, paired with a caution about sunburn and excessive exposure. The narrative invites readers to reconsider conventional wisdom about sun exposure, highlighting that moderate and frequent exposure may be among the positive influences on health, with the caveat that protection against sunburn remains important.

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During the pandemic, the speaker took 1,000-3,000mg of Vitamin C but currently takes none due to a balanced microbiome. Testing confirms good bifidobacteria levels, especially during summer with outdoor microbe exposure. Vitamin D from the sun also boosts bifidobacteria. Vitamin C intake may need to increase depending on location. As people age, skin produces less Vitamin D, making Vitamin D and K2 the most important vitamins for older individuals.

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Eighty-five percent of the world's population is clinically deficient in vitamin D3, a nutrient humans make from sunlight and cholesterol. Vitamin D3, or cholecalciferol, is arguably the most important nutrient in the human body. People have been taught to fear the sun, but most are not getting enough. The rise in skin cancer incidence is superimposable with the use of sunscreen. Since 2018, multiple brands of sunscreen have been pulled from the market for directly causing skin cancer.

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Vitamin D toxicity is described as extremely rare, and is said to involve only one symptom: elevated calcium in the bloodstream. The speaker references Bruce Hollis, a recognized pioneer in vitamin D research, and asks whether a vitamin D toxicity problem has ever been observed. Hollis allegedly responded that he has never seen such a problem, despite involvement in numerous vitamin D studies. The transcript asserts that developing any toxicity would require consuming hundreds of thousands of international units of vitamin D3 for months. Taken together, the remarks suggest a high safety margin for vitamin D intake under typical conditions, with toxicity appearing only after extraordinary, prolonged consumption.

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- I talk a lot about vitamin D but I wouldn't recommend taking vitamin D by itself. - I would always take vitamin K2 with vitamin D because vitamin D3 increases calcium absorption in your intestines by 20 times and that ends up in the blood so you can have a lot of calcium in the blood which can be a problem for people especially if they're prone to kidney stones or arthritis but vitamin k two comes to the rescue and that takes the calcium from the blood and pushes it into the bone. - One of the really important things that vitamin K2 does is to prevent soft tissue calcium from accumulating. - That could be in your arteries or the joints or any organ. - So to protect you against any potential side effects of vitamin D3, make sure you take vitamin K2 at the same time. - And as far as the ratios go, for every ten thousand IUs of vitamin d three, take a hundred micrograms of vitamin k two.

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There is a flood of research on what vitamin D can do for cancer, and it helps in many different ways. Research that shows vitamin D doesn't help is influenced by big pharma. Studies that don't show a favorable outcome use tiny amounts of vitamin D, which is why they don't create the desired effects.

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Did you fall for this vitamin D trick?

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Vitamin D3 is the most purchased and consumed vitamin, advertised as essential for immunity. Vitamin D is known for its immunomodulatory, anti-inflammatory, antiviral, antioxidative properties. The sun is the most efficient method to get vitamin D, yet doctors may prescribe supplements, prompting the vitamin D paradox. Vitamin D testing surged from 2000 to 2010, an 83-fold increase, while cod liver oil early in the 1930s led to fortifying milk and eradicating rickets. The narrative shifted from sunlight to pills, fueled by capitalism and marketing. UVB triggers vitamin D synthesis in the skin; UVA interacts with melanin. Umelanin and fmelanin determine protection and vitamin D absorption; more melanin means more protection but less D production. Vitamin D is fat-soluble and stored, released as needed by sequestration. Modern indoor life and migration reduce sun exposure, contributing to vitamin D deficiency—especially among Black Americans. There is no healthy tan; sunlight also influences ghrelin, mood, and blood pressure.

The Joe Rogan Experience

Joe Rogan Experience #502 - Dr. Rhonda Patrick

Guests: Dr. Rhonda Patrick

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In this episode of the Joe Rogan Experience, Dr. Rhonda Patrick discusses various topics related to health, nutrition, and the biological mechanisms behind stress and anxiety. She explains the role of dynorphin and endorphins in managing anxiety and how the feeling of anxiety before performing can lead to a greater endorphin rush afterward. They explore the concept of hormesis, where mild stressors, such as exercise or certain foods, can have beneficial effects on the body by activating stress response mechanisms. Rogan and Patrick delve into the importance of exercise for mental health, neurogenesis, and the production of brain-derived neurotrophic factor (BDNF), which supports the growth of new neurons. They discuss the significance of serotonin in memory and mood regulation, and how its levels can be influenced by various factors, including diet and exercise. The conversation shifts to the role of vitamin D in health, with Patrick emphasizing that many people are deficient in it and that it plays a crucial role in various bodily functions, including immune response and mental health. She highlights the need for adequate vitamin D levels for optimal health and discusses the potential implications of low levels on conditions like autism. They also touch on the importance of antioxidants and the misconceptions surrounding their use. Patrick critiques the oversimplification of the effects of vitamins and antioxidants, particularly in the context of cancer prevention and treatment. She argues that context is essential when evaluating the benefits of supplements, as the effects can vary significantly based on individual health status and existing deficiencies. Patrick mentions the potential of stem cell research and the exciting developments in regenerative medicine, including the possibility of reprogramming cells to reverse aging effects. They discuss the implications of recent studies showing that young blood can rejuvenate old mice, enhancing their physical and cognitive abilities, and the potential for similar applications in humans. The episode concludes with a discussion on the challenges of obtaining funding for innovative research in nutrition and aging, emphasizing the need for continued exploration in these fields. Patrick promotes her app, FoundMyFitness, which provides resources on health and nutrition, and encourages listeners to engage with her work through her website and social media.