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Multiple trials have been conducted on Ivermectin, but none have proven its effectiveness, according to Speaker 0. However, Speaker 1 argues that there is a significant body of evidence, including randomized controlled trials and studies, supporting the use of Ivermectin for COVID. They mention countries like India, Mexico, and nations in Central Africa, as well as the Tokyo Medical Association endorsing its use. While some doctors and scientists have criticized certain trial methodologies, claiming that there is no science to support Ivermectin for COVID is false. Speaker 1 also highlights that experienced critical care doctors worldwide have prescribed Ivermectin based on available data and their own expertise, dismissing the characterization of the drug as a horse dewormer. Speaker 2 adds that research conducted by DARPA in the early 2000s recommended Ivermectin as a top product for a coronavirus pandemic due to its antiviral and immune modulatory properties, which had been proven in vitro and in vivo. These medications have been safely used in humans for several decades.