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Taking too much vitamin B6, especially from high-dose supplements, can damage nerves, sometimes permanently, causing sensory neuropathy with symptoms like numbness, tingling, burning pain, and difficulty walking. Neurologists should ask patients with neuropathy about vitamin use, particularly B6. The daily recommended amount of B6 is between 1.3 and 2 milligrams, with an upper limit of 100 milligrams, though some experts recommend lower limits, such as 12 milligrams per day. Studies show that doses above 50 milligrams daily, or even lower doses taken for over a year, can be toxic. Over-the-counter supplements often contain much more than this. Individual reactions vary; some tolerate 500 milligrams daily, while others develop neuropathy from just 6 milligrams. High-dose B6 is necessary for some medical conditions, but for the average person, a balanced diet provides enough B6, and megadoses are unnecessary and potentially harmful.

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Low B vitamins and DHA can cause cognitive issues. One person experienced improved motivation after addressing a B12 deficiency. Vitamin B12 is essential and must be obtained from external sources like meat, eggs, or supplements. A high dose of vitamin C, zinc, and B12 can help the body fight off illness. One person recommends Nuzava B12 drops, suggesting viewers purchase them to avoid deficiency while they are still in stock.

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Speaker 0 argues that the food supply is treated with a chemical called folic acid, which is not a natural vitamin and did not exist until the 1980s. According to the speaker, folic acid is not found anywhere on the surface of the earth, whereas folate does exist in nature. The speaker notes that during pregnancy, women are told to take high doses of folic acid, and questions why a man-made chemical that didn’t exist until the eighties is deemed absolutely necessary for a healthy pregnancy. The comparison is made between folate and methylfolate, implying a distinction between natural forms and synthetic forms. The speaker also states that in the United States, the entire grain supply—flour, rice, bread, pasta, grains of any kind, and cereals—is required to be sprayed with folic acid, although this is not openly labeled as such. Instead, it is described as fortified or enriched foods. The speaker claims that these fortified or enriched nutrients are fed to children, and asserts that half of the population has a gene mutation that prevents them from processing folic acid effectively. The consequence, according to the speaker, is that when a person cannot process a high amount of something introduced into the body, it becomes dysfunctional. The speaker then connects this to a broader societal issue, describing a common scenario: a child goes to school, comes home with a phone call reporting inattention and poor ability to follow directions, and the ensuing medical response is the prescription of stimulants such as Adderall or Ritalin. The speaker characterizes this as a solution that uses amphetamines to accelerate the central nervous system to match the pace of a racing mind, rather than addressing underlying factors. Ultimately, the speaker presents a proposed solution: remove folic acid, fortified, and enriched nutrients from the diet, and observe changes in behavior. The underlying claim is that eliminating these synthetic nutrients would calm behavior and improve function, implying that the current approach relies on artificial chemistry rather than natural nutrition.

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We send toxic chemicals like hydrogen cyanide from human sewage treatment plants to compound pharmacies, who use them in supplements and energy drinks like Celsius. These products can contain four times the daily limit of cyanide. Instead, choose Bang over Celsius or Monster, as Bang uses methylcobalamin instead of cyanocobalamin. Check your supplements for cyanocobalamin and discard them if found, including those for your children.

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We use dangerous chemicals in supplements and energy drinks. For example, Celsius energy drink contains 4 times the safe amount of cyanide. Instead, choose Bang with methylcobalamin, not cyanocobalamin. Hydrogen cyanide in these products comes from human sewage treatment plants. Check your supplements for cyanocobalamin and throw them out if they contain it, including those for your kids.

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Lack of vitamins, particularly Vitamin B, can contribute to depression. Some psychiatrists are using high doses of vitamin B3 (nicotinic acid) to treat mental illness. A DVD called "Food Matters" highlights the importance of nutrition in health, sharing a story of a girl who recovered from a catatonic state after taking high doses of nicotinic acid. Lack of progesterone can also lead to depression, especially in women who have been exposed to chemicals or plastics. Balancing hormones and implementing the 8 laws of health can help ease off antidepressants. Excess pain, food, and stimulation can also contribute to chemical imbalances in the brain and should be addressed.

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Many Australians report vitamin B6 toxicity from supplements, leading to symptoms like numbness, heart rhythm issues, muscle loss, and hospitalization. Cases arose after an Australian broadcast highlighted the issue of inadvertent poisoning from excessive synthetic vitamin B6. Vitamin B6 is often included in supplements like zinc and magnesium. While the recommended daily intake is 1.3 to 1.7 milligrams, some supplements contain 100 milligrams. High doses are sometimes used to treat deficiencies, but regular supplementation differs. The TGA regulates products exceeding 10mg as medicines, emphasizing the need for consumers to understand supplement ingredients and ensure they align with their healthcare needs.

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OBGYNs advise pregnant women to take high doses of folic acid, a man-made chemical not found in nature, to prevent neural tube defects. However, folic acid doesn't prevent anything. The prescription of folic acid began due to a pandemic of neural tube defects in newborns, which research linked to methylfolate deficiency. Instead of prescribing methylfolate, a cheap, man-made version called folic acid was used. Folic acid is the most prevalent nutrient in the U.S. diet, sprayed on grains, cereals, pasta, flour, and rice, labeled as "fortified" or "enriched."

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According to the speaker, the best way to get all your minerals and vitamins naturally is through specific plants. They claim our physical makeup comprises 102 minerals, and that every sickness can be traced to a mineral deficiency, agreeing with Linus Pauling. Burdock root contains all 102 minerals in trace amounts. Irish sea moss contains 92 of the 102 minerals in concentrated amounts. Bladderwrack seaweed combined with burdock root and sea moss will provide all 102 minerals. For vitamins, the speaker recommends moringa powder, which they claim has the highest concentration of vitamins of any plant.

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And we also have another thing in liver called biotin. I've already talked about that. Biotin will help increase the structure of the hair, the shaft, so your hair becomes thicker, stronger, more elastic, fuller look, as well as the growth of hair itself. Getting Biotin from grass fed liver is way better than getting it from a supplement. If you had an antibiotic and then all of a sudden your hair starts becoming a problem, then you need more biotin or actually you need more grass fed liver. Anyway, I wanted to keep this video real short, I wanted to give you some really important foods for the hair

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Cheap supplement brands often use synthetic nutrients derived from sources like ground limestone. Studies suggest that isolated calcium carbonate supplements can increase the risk of heart disease, stroke, and heart attack. The body struggles to utilize synthetic calcium without accompanying nutrients like magnesium, leading to arterial calcification. This calcification hardens the arteries, elevating the risk of heart disease. Therefore, taking synthetic multivitamins could potentially increase the likelihood of dying.

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I'm trying to filter through vitamins and minerals that are not synthetic. Well, vitamins and minerals, those would all be synthetic. When you go back into who made the first vitamin, have the John D. Rockefeller. The oil companies are making the vitamins. So if you are consuming vitamins, you are bringing a petroleum based product into your body. So when you're to sort through vitamins and minerals, you should just stick to food. And if you think about it, if you were looking for something from nature, you would grab an organic orange and you would eat that whole orange. You would eat the peel, you would eat the flesh, you would eat the skin and the seed. And that's it. So when you want to heal the body, you need to stick to food.

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The video discusses eight foods high in vitamin B7 (biotin), which may help with thinning hair or hair loss. The highest sources are beef liver, chicken liver, wild-caught salmon, and egg yolks. Vegetarian and vegan options include broccoli, cauliflower, romaine lettuce, almonds, and tomatoes. However, those with autoimmune, thyroid, or gastrointestinal issues like candida or leaky gut may find the vegetarian and vegan options difficult to digest. Animal products may be more easily digestible in these cases. Vegans and vegetarians may choose to supplement while maintaining their diet. More information is available below.

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B vitamins are water soluble, so they must be consumed daily to be absorbed, and the portion that isn’t absorbed passes through the body. A large dose of vitamin B2 (riboflavin) can make your urine turn a bright yellow, indicating excess B vitamins are being excreted. The body uses what it can from these nutrients, but the guidance is to top them up on a daily basis to maintain adequate levels. This recommendation is especially emphasized if you have a specific condition related to one of these crucial nutrients. In short, daily replenishment helps ensure absorption and prevents unnecessary buildup, since any excess is likely to pass through the system.

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- Eight foods highest in vitamin b seven biotin. - If you are struggling from thinning hair or hair loss, this is the video for you, so make sure to watch until the end. - The first one is beef liver. - Then we have chicken liver, wild caught salmon, egg yolks, and then we have vegetarian and vegan options, which is broccoli and cauliflower, romaine lettuce, almonds, and of course, tomatoes. - And these vegetarian and vegan foods, they may not be that easy to digest if you already have these issues. - That's why animal products win in this case. - However, I understand that if you are, you know, vegan or vegetarian, you may want to supplement and still be on the diet. So I leave the choice free to you, and read below for more info.

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The speaker asserts that a common vitamin C supplement has a problematic underlying issue. They state that vitamin C supplements are ascorbic acid, and that synthetic ascorbic acid is produced from GMO corn. The speaker notes that the vast majority of GMO corn is sprayed with Roundup, the glyphosate weed killer. They claim that, in head-to-head studies, naturally occurring vitamin C found in foods such as oranges versus synthetic ascorbic acid shows benefits for humans, whereas the synthetic form does not appear to have the same impact. The speaker refers to a specific head-to-head study comparing camu camu berries to ascorbic acid in smokers, and they report that only naturally occurring vitamin C from camu camu berries lowered oxidative stress. They also mention observational studies in which the consumption of synthetic vitamin C has been associated with worsening metrics of cardiovascular disease. Based on these points, the speaker presents a takeaway: the synthetic form of vitamin C is derived from GMO corn, and consuming more of this synthetic form may be less healthy, while consuming the naturally occurring vitamin C from sources like camu camu berries or other natural sources could be more beneficial. The overall message emphasizes two main claims: (1) synthetic ascorbic acid is produced from GMO corn, which is largely treated with Roundup glyphosate, and (2) evidence from head-to-head and observational studies suggests that naturally occurring vitamin C provides benefits or oxidative stress reductions that the synthetic form does not, with observational data linking synthetic vitamin C to worse cardiovascular metrics. The speaker concludes that, to be healthy, one should eat more of the naturally occurring vitamin C sources and less of the synthetic ascorbic acid.

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Speaker 0 explains that you can lose weight eating pasta and bread in Europe, but in the United States a bowl of pasta and a basket of bread can leave you sleepy and in a bad mood; in Italy, a fat bowl of pasta makes you feel amazing. The reason given is that in 1993 the chemical industry allegedly convinced the federal government that grain supplies needed to be sprayed with folic acid, so all flour, bread, pasta, and cereal became enriched. Enriched foods are described as being sprayed with folic acid. Folic acid is labeled as a man-made chemical produced in a laboratory and not found naturally anywhere on Earth. The speaker emphasizes that folic acid is the most prevalent nutrient in the human diet. The message is not to avoid grains, rice, pasta, cereals, or bread, but to eat non-enriched versions of those foods—the organic versions.

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- We take that chemical weapon that's an acute toxic flammable environmental hazard and ship it to compound pharmacies that put it in supplements, protein powders, and energy drinks. - Celsius energy drink has four times the amount of daily cyanide that a human being is meant to ingest. - Bang has methylcobalamin; this has cyanocobalamin. - Hydrogen cyanide is sourced from sewage treatment plant sludge—the waste from a human sewage treatment plant, called sludge. - They dry it into powder, ship it to a facility, synthesize it with a metal, and put it in your vitamins; they take metal, hydrogen cyanide, and put it in our supplements. - When you get home tonight, take all of your supplements and protein powders, look for cyanocobalamin, and if it has it, throw it in the trash. Do that for your kids too.

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Foods labeled "fortified" or "enriched" are sprayed with folic acid. Unless it's organic, white food should be avoided. Even some organic products are fortified or enriched, so look for organic sources that are not. Some people report feeling unwell after eating sandwiches or pizza in the US, but feel fine eating pasta and bread in Italy. This is because the bread in the US contains persal cedar and high amounts of filling gas.

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Vitamin D3 is popular, but I advise against it. It's made from rat poison's active ingredient, causing hypercalcemia. Big pharma profits more from vitamins than drugs. Pfizer's investment led to a 90% deficiency rate. D3 is made from radiated sheep's wool and toxic chemicals, then added to GMO soybean oil. The sun is better than a pill. Share natural ways to boost vitamin D for a free guide.

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Liver contains biotin, which can improve hair structure, making it thicker, stronger, more elastic, and fuller-looking, while also promoting hair growth. Obtaining biotin from grass-fed liver is superior to supplementation. If hair problems arise after antibiotic use, increasing biotin intake, specifically through grass-fed liver, is recommended. The speaker aimed to provide information on important foods for hair health.

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The body may be deficient in vitamin B12 if one experiences mental conditions like depression, bipolar disorder, or schizophrenia; cognitive issues similar to Alzheimer's or dementia; or a loss of smell and taste. Burning sensations in the mouth or tongue, sudden blurred vision, and balance problems can also indicate a B12 deficiency. It is important to supplement with methylcobalamin, the natural form of B12, rather than cyanocobalamin.

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There is a flood of research on what vitamin D can do for cancer, and it helps in many different ways. Research that shows vitamin D doesn't help is influenced by big pharma. Studies that don't show a favorable outcome use tiny amounts of vitamin D, which is why they don't create the desired effects.

The Ultimate Human

Rose Ferguson: Live Q&A on MTHFR Gene Mutation, Autoimmune Disease and Cognitive Decline | TUH #213

Guests: Rose Ferguson

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Gary Brecka and Rose Ferguson host a Q&A, offering insights into nutrition, biohacking, and health. They stress a holistic approach, often connecting health issues to gut function and genetics. For teenagers, they recommend whole foods over addictive processed options, suggesting genetic methylation tests for personalized supplementation with methylated multivitamins and multiminerals. Protein intake is crucial, with Gary promoting "Perfect Amino" for its high bioavailability and lack of caloric impact, especially for those struggling to meet protein goals. Rose advocates for diverse protein sources, including fiber-rich plant proteins. Both caution against peanuts due to mold, mycotoxins, and lectins, which can cause leaky gut. Gut health is a core focus, identified as a root cause for 85% of autoimmune diseases, IBS, and skin conditions like rosacea, eczema, and psoriasis. Factors like stress, alcohol, poor sleep, antibiotics, and mycotoxins disrupt the gut's single-cell lining, leading to inflammation and systemic issues. Hydration, minerals, and therapies like red light and contrast baths are suggested for skin health. Regarding vegan diets, they advise careful preparation, emphasizing protein from sources like hemp seeds, and avoiding processed plant-based foods and heavily sprayed, genetically modified grains. The hosts clarify that widespread gluten sensitivity often stems from modern food processing, particularly fortification with synthetic folic acid, rather than gluten itself. They link the MTHFR gene mutation, affecting nearly half the population's ability to process folic acid, to ADHD and postpartum depression, recommending methylated folate and avoiding fortified foods. They also strongly advise against cyanocobalamin (synthetic B12) due to its cyanide content. Hair loss, including alopecia, is discussed, with Gary suggesting exosomes or topical finasteride and linking it to maternal genetics, DHT, thyroid issues, and stress. The conversation shifts to longevity versus sports performance, where extreme performance often "borrows from the future." Longevity protocols prioritize whole foods, sleep, strong relationships, and appropriate exercise. For Alzheimer's and dementia, termed "Type 3 diabetes" (insulin resistance in the brain), prevention involves maintaining a low glycemic profile, insulin sensitivity, intermittent fasting, and adequate sleep. Gary controversially highlights a strong correlation between statin use and cognitive decline. Finally, heavy metal detoxification protocols are mentioned, emphasizing specific testing methods.

The Peter Attia Drive Podcast

#46–Chris Masterjohn, Ph.D.: Pathways to health and disease (NAD, sirtuins, methylation, choline...

Guests: Chris Masterjohn

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In this episode of The Drive, Peter Attia interviews Chris Masterjohn, a nutrition scientist with a PhD, discussing various topics related to nutrition, health, and longevity. The conversation begins with Attia explaining the podcast's ad-free model, emphasizing the importance of trust and the value of listener support. He highlights the extensive research and resources that go into creating the podcast, including detailed show notes. The discussion shifts to choline, where Masterjohn explains its critical role in preventing non-alcoholic fatty liver disease (NAFLD) and its importance in methylation processes. Choline deficiency can lead to severe health issues, including fatty liver, which is becoming increasingly prevalent in the U.S. Attia and Masterjohn delve into the mechanisms of fatty liver disease, emphasizing the need for adequate choline intake to facilitate fat export from the liver. They also explore the MTHFR and COMT genes, which are involved in methylation and neurotransmitter metabolism. Masterjohn discusses how variations in these genes can affect individuals' methylation capacity and overall health, particularly in relation to homocysteine levels. He notes that individuals with certain MTHFR mutations may require higher choline intake to maintain metabolic health. The conversation touches on the use of nicotinamide riboside (NR) and its potential benefits and drawbacks. Masterjohn expresses skepticism about the efficacy of NR supplements, particularly regarding their impact on methylation and homocysteine levels. He suggests that while some individuals report positive effects from NR, the underlying biochemical mechanisms remain unclear, and the potential for increased methyl donor depletion is a concern. Attia and Masterjohn discuss the importance of dietary sources of choline, such as eggs and liver, and the role of creatine in supporting methylation processes. They emphasize the need for a balanced approach to supplementation, considering individual genetic variations and dietary habits. Throughout the episode, Masterjohn shares insights into the complexities of nutrition science, the importance of understanding individual biochemistry, and the need for more research to clarify the effects of various supplements on health outcomes. The conversation concludes with a discussion on the importance of personalized nutrition and the potential benefits of a holistic approach to health.