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Dr. Alexis Cohen (Jasmine Cohen) and the host discuss a wide-ranging view of health, science, and society, centered on mitochondria, light biology, and decentralized approaches to knowledge and healing. - On science, health, and authority: - Cohen argues that “we really haven’t been doing science for about seventy years now” and that modern science has become scientism, with people looking to scientists and doctors as authority figures over personal health, even though no one can fully know another’s lived body experience. - She emphasizes that aging is a reflection of mitochondrial heteroplasmy and that there are ways to slow or speed that burden, but contemporary living habits harm mitochondrial health. She asserts there are incentives to promote lifestyle advice that is not monetizable (outdoor activity, barefoot grounding, seasonal eating, movement), which she says slows research and access to information. - The conversation asserts a need to reclaim personal authority over health and to recognize life as magical and miraculous. - Personal entry into Bitcoin and crypto curiosity: - Cohen notes she and her partner became interested in Bitcoin in 2018, with a continued engagement including taking a cryptography course to understand the underlying proofs rather than accepting information at face value. - Background and work: - The host introduces Cohen as a Princeton-trained molecular biologist, a PhD focusing on metabolism, gut health, and circadian biology, who shifted from academic research to helping people rebuild health through nutrition, movement, mitochondrial function, and light exposure. Cohen shares that her own childhood illnesses, weight issues, and colitis prompted a pivot from academia to health coaching, emphasizing ownership of wellbeing through science and practical lifestyle strategies. - Cohen highlights that she values rigorous science but seeks practical lifestyle strategies to empower clients to understand their biology and take ownership of their health. - Dance, embodiment, and biology: - Cohen describes taking up social dancing (salsa, bachata, merengue, fox trot, hustle) and training intensely. She explains dancing challenges the brain in novel ways, requires being guided by a partner, and expands neural connections. - The host shares similar experiences with dance, noting body memory across decades and the importance of movement, rhythm, and social connection for health. - Mitochondria, heteroplasmy, and light: - Cohen explains mitochondria as the battery of the cell, with their own circular DNA and multiple roles in ATP production, biosynthesis, and epigenetic regulation. Heteroplasmy, the mutation burden in mitochondrial DNA, reflects dysfunction that can lead to energy production deficits across tissues. - She notes three key mitochondrial outputs: - ATP production powers cellular processes and metabolism. - Metabolic water production (including deuterium-depleted metabolic water). - Biophotons, photons largely in the UV range, emitted by mitochondria and nucleus during electron transport; older, sicker individuals emit more light due to increased permeability of the system. - Cohen argues aging mirrors mitochondrial heteroplasmy and mutation accumulation, with higher mutation burdens in tissues like immune cells, gut, liver, and brain associated with disease. She also discusses that mitochondria contribute to energy, water, and biophotons, and that modern life elevates heteroplasmy by lifestyle choices. - She argues heteroplasmy can be slowed or sped, and that there are actionable interventions—though the exact list is not exhaustively enumerated in this segment. - Why mitochondrial health isn’t the central target: - Cohen says mitochondrial health research is less profitable because it emphasizes lifestyle and environmental changes rather than drugs, which affects funding and research direction. She describes a system where focusing on broad environmental and lifestyle changes could be financially less lucrative than drug-centered approaches. - She expands on historical dynamics in science, including siloing of scientists and the development of a paywalled academic publishing model, suggesting that the system discourages holistic, integrative approaches that would unify mitochondrial biology with systems biology. - Light, circadian biology, and UVA/UVB: - The discussion shifts to light as a regulator of mitochondria. Cohen divides the sun’s spectrum into ultraviolet (UVB and UVA), visible light, blue light, and near infrared (NIR). She emphasizes that near-infrared light penetrates deeply and stimulates mitochondria, while UVB promotes melanin production via POMC and MSH peptides, affecting energy balance, mood, and metabolism. - UVB light triggers alpha-MSH and beta-endorphin production, the latter contributing to mood and dopamine support, and helps regulate energy expenditure and appetite via POMC-derived pathways; UVB exposure supports melanin synthesis, redox balance, and photoreception across tissues. - UVA light activates Neuropsin receptors on eyes and skin, aiding circadian entrainment and nitric oxide production, which improves vasodilation and nutrient delivery. Neuropsin is present in skin and testes; its stimulation is linked to testosterone and fertility enhancements. UVA also helps anchor local circadian rhythms in tissues. - Cohen discusses the misperception that UV light is universally harmful and argues that melanin is not only protective but can facilitate energy capture from high-energy photons to support energy metabolism in humans. Melanin’s roles extend beyond protection to potential energy transduction, with POMC, MSH, and alpha-MSH linking light exposure to metabolic regulation. - The My Circadian app is recommended as a tool to track sunrise, UVA/UVB rise, and lux (brightness) to optimize exposure. Cohen notes indoor environments rarely exceed 1000 lux, while outdoor brightness can reach 60,000–60,200 lux, significantly impacting serotonin production, mood, and cognition. She emphasizes the importance of bright daytime light for circadian alignment and melatonin suppression at night. - Infrared, LEDs, and indoor lighting: - The conversation covers lighting technologies, noting fluorescent tubes and LEDs minimize near-infrared and maximize blue light, which disrupts circadian rhythms and flicker, stressing the eyes and sympathetic nervous system. Cohen argues that modern lighting deprives people of infrared and UV radiation, both critical for mitochondrial function and circadian health. - She criticizes the push for energy efficiency that reduces thermal and infrared energy, arguing it contributes to systemic health issues. She emphasizes the importance of incandescent and near-infrared-rich lighting for indoor environments and sun exposure to sustain metabolic health. - Grounding, EMF, and environmental exposure: - Grounding (direct contact with the earth) is presented as a way to discharge excess positive charge in tissues, reducing inflammatory burden and supporting mitochondrial function. Cohen shares practical grounding instructions—grounding directly to the earth when possible, wearing natural fibers, and using grounding footwear. - Non-native electromagnetic fields (EMFs) from Wi-Fi, Bluetooth, 5G, and other sources are discussed as contributors to mitochondrial dysfunction and inflammation. Cohen cites Robert Becker’s historical work on non-thermal EMF effects and Havana syndrome as context for potential biological risks. She suggests practical mitigation, including reducing EMF exposure, using Ethernet where possible, and using tinfoil to shield exposure in certain situations. Plant life can absorb EMF, and grounding, sunlight, and strategic use of red and infrared light are recommended to compensate where exposure is high. - The discussion includes practical home strategies, EMF-blocking window panels, EMF-blocking paint, and even temporary shielding (e.g., tinfoil) as a do-it-yourself mitigation approach. - Travel, circadian disruption, and protocols: - Cohen outlines travel challenges: high altitude cosmic radiation exposure (non-AVMF exposure), cabin EMFs, circadian misalignment, and sedentary behavior. She suggests pre- and post-travel strategies such as grounding, sun exposure, hydration, lymphatic support, and blue-light management to ease time-zone transitions. - She promotes an ebook protocol focused on lymphatic support and circadian realignment, available for purchase, with a holiday discount code holydays. Blue-light blocking strategies and red-light strategies are included to facilitate adaptation to new time zones. - Health, mental health, and pediatric considerations: - The hosts discuss mental health concerns, including PTSD, anxiety, and depression, emphasizing circadian regulation, light exposure, sleep hygiene, and reducing screen exposure. Cohen notes the importance of bright daytime light and a dark, cool sleeping environment for sleep quality and mood. She mentions a study showing even small nighttime light exposure can influence daytime metabolic markers, emphasizing the importance of darkness at night. - Birth, medications, and vaccines: - They touch on birth experiences, epidurals, and how early life interventions can influence long-term health and microbiome development. Cohen discusses pain as a portal to healing and critiques reliance on certain pharmaceutical approaches. - On vaccines, Cohen describes observed adverse effects post COVID-19 vaccination, including histamine issues, barrier permeability, and rapid cancer reports linked to vaccine exposure, while underscoring the lack of widespread funding to investigate these relationships. She mentions turbo cancers and batch variation as topics already discussed by researchers like Kevin McKernan and a need for independent inquiry. - Decentralization, science, and Bitcoin again: - Cohen envisions a decentralized health system in which multiple modalities (acupuncture, Chinese medicine, Ayurveda, allopathic medicine) can be tested for proof of work, with outcomes guiding what works best for individuals. She believes decentralization is necessary for genuine innovation, with a future vision of a decentralized, funded light research lab and a retreat model to study circadian biology, mitochondrial function, and nature-based health in diverse environments (North America and equatorial regions). - She sees Bitcoin as a tool that enables financial sovereignty and autonomy, providing an opportunity to fund decentralized science and publish findings on blockchain to protect against censorship. She highlights the potential for Bitcoin to support a lab through deflationary funding and to empower researchers and patients alike. - Closing: - The conversation closes with practical resources: Thinkific-hosted classes, an online book club, and a QuantumU course that reframes science education around decentralized, nature-based principles. Cohen emphasizes accessible contact options (Instagram and email) and a holiday discount for courses and ebooks. The participants express enthusiasm for ongoing collaboration, travel and events, and continued education in Bitcoin, science, and holistic health. Overall, the episode centers on mitochondria as a foundational health driver, the essential role of light and circadian biology in energy, mood, metabolism, and aging, and a call for decentralized, nature-aligned science, with Bitcoin framed as a funding and governance tool to empower individuals and researchers to pursue health innovation beyond centralized institutions.

- First of all, red light therapy, when done properly, can stimulate collagen. - It can stimulate the growth of fibroblasts in the skin and decrease the appearance of wrinkles and fine lines. - Number two, it actually decreases inflammation and increases blood flow, which is very useful when talking about rejuvenation. - It can also improve wound healing and decrease hair loss, and it's been used for many years successfully to do this. - Now red light therapy can also reduce acne and eczema. - Some people have also reported a decrease in the incidence of cold sores. - If you're taking certain medications, it can actually increase the risk of complications. - So you might wanna talk to the doctor who's prescribing your meds and see if red light therapy is gonna be safe for you before you start. - In any case, if you're using

Red light therapy, or photobiomodulation, is described as the body responding to light it is biologically designed to respond to, especially red light and near-infrared light. Jonathan Otto explains that the technology has historical roots, with Nobel Prize context in 1903 for light therapy (Niels Ryberg Finsen) and early work by John Harvey Kellogg; red light therapy as known today was advanced by Andre Mester in the 1960s and further developed with LED technology funded by NASA, enabling high power delivery with minimal heat. Key evidence and claims: - In major clinical studies, red light therapy is being explored as an alternative or adjunct to palliative chemotherapy, radiotherapy, and surgery in cancer. The Lancet Oncology published a trial with 413 men in which the red light group did almost 400% better than the non-red-light group; only 6% in the red light group required surgery versus 30% in the non-red light group, a claimed 500% difference in that aspect. - In a lymphoma pilot study (PubMed, 2006), three patients achieved complete remission within a week after photodynamic therapy with methylene blue, with no side effects reported and pain easily managed. - University College London conducted studies showing 49% remission in a red-light group versus 13.5% in a non-red-light group in a prostate cancer context when combined with a photosensitizer; separate eyesight research with 6, seven 0-nanometer parameters demonstrated immediate improvements, with larger long-term effects reported in various other conditions. - Red light therapy is claimed to impact a broad range of conditions: eyes (macular health, myopia in children), autoimmune diseases (Hashimoto’s thyroiditis, autoimmune thyroiditis), hair loss (androgenic alopecia), skin conditions (acne, eczema, psoriasis), chronic pain (arthritis, back pain), depression and anxiety (rapid improvements noted within hours in some studies), and post-stroke or neurodegenerative conditions (mood, cognitive function, overall energy). - Specific eye-related findings include a large trial where 41 clinical trials in children showed the therapy stopped vision worsening in many cases; in the UCL eyesight study, 70–80% near-infrared penetration targets deeper tissues, with evidence of rapid improvements in vision when light was delivered in the morning or near the eyes at 670 nm in LED form. - In thyroid and metabolic contexts, there are reports of thyroid medication reduction and remission in chronic autoimmune thyroiditis with certain dosing regimens (e.g., 20 minutes twice a week for five weeks in a trial cited), and a Hashimoto’s thyroiditis study showing substantial medication reduction. - Hair growth is reported to respond to red light therapy due to stimulation of hair follicles and scalp stem cells; anecdotal reports include improved hair density and delayed graying in some individuals. - The therapy is claimed to affect fat loss via photonic lipolysis and to modulate mitochondrial function, with mitochondrial chromophores described as light receptors in about 25% of cellular organ content, generating reactive oxygen species and ATP to drive cellular energy. - A long-COVID study by the European Society of Medicine reported four sessions of 64–84 minutes each yielding total remission of all symptoms in 60 of 62 participants within one week; two others improved with the same protocol. - Dosing guidance and safety: thousands to millions treated with red light therapy have reported minimal adverse effects; overexposure can occur, but the majority of clinical experience indicates a favorable safety profile; a dark period and sleep in darkness are noted as important to maximize benefits. - Delivery devices: panels that deliver broad-spectrum light (including multiple wavelengths such as 630 nm, 660 nm, 670 nm, 810–860 nm, 1060 nm) are preferred for broad organ coverage and deeper tissue penetration; these devices aim to deliver high irradiance (e.g., over 200 milliwatts per square centimeter at about three inches) to accelerate healing and support whole-body photobiomodulation. - Practical use: exposure parameters vary by condition, with some studies showing immediate or rapid improvements (e.g., eyesight within 24 hours in some trials; depression or anxiety improvements within hours; autoimmune symptoms over weeks), while others report improvements sustained for months if therapy is continued, though some benefits persist beyond cessation in certain conditions. Historical and practical context: - The interview frames red light therapy as a natural, noninvasive modality that aligns with the body’s use of light for healing, contrasts it with more invasive conventional therapies, and positions it as having broad clinical study support across multiple journals (including The Lancet Oncology, British Medical Journal, and other major journals). It’s presented as a scientifically backed, broadly applicable therapy that can be used at home with high-quality devices. Applications mentioned: - Cancer and tumor-targeted approaches (photodynamic therapy), eyes and vision, autoimmune thyroid disease, skin conditions, hair growth, wound and tissue healing, pain and inflammation, mood disorders, long COVID, and metabolic effects such as fat reduction and thyroid regulation.

Mitochondria, you know, the energy producers, the powerhouses within every cell. Brain cells may have as many as a thousand mitochondria in each neuron. Mitochondria are seen diffusely throughout the body in virtually all of our cells, interestingly, not in our red blood cells, but certainly in our white blood cells. And having good mitochondrial function and numbers within our white blood cells, is an important player as it relates to a proper effective immune function and keeping, inflammation in balance. They recognize the importance of dysfunction or problems with the mitochondria, as being a major risk factor in things like obesity, diabetes and hypertension.

Speaker says that long wavelength light—red light from sunlight, infrared, and near infrared light—is beneficial for us. It is low energy, can pass into the body, and supports mitochondrial health by charging the mitochondria. The speaker recently learned that the water surrounding the mitochondria absorbs red light in the same way the ocean absorbs red light, which is why the ocean appears blue and reflects blue. The mitochondria are described as having a “mini ocean” surrounding them that absorbs red light.

Researchers recruited 22 individuals and randomized them into two groups: control and experimental. Both groups had a baseline color contrast test, which assesses visual function. Participants worked in a building with abundant artificially lit LEDs and fluorescent lighting, a spectrum with a big spike in blue light and very low red light and zero infrared light. After two weeks of working under these conditions—described as conditions the participants had experienced for the last two years—there were zero improvements in color contrast in the control group. In the experimental group, researchers added two desk lamps, each equipped with a 60-watt incandescent bulb. The incandescent bulbs provided a spectrum that added abundant infrared light, introducing longer wavelengths similar to sunlight. After two weeks of this infrared light supplementation, color contrast tests were retaken. The experimental group showed a 28% improvement in protan thresholds and a 24% improvement in tritan thresholds. After the incandescent lights were removed, improvements persisted four weeks later and six weeks later, with no other changes to the lighting. The mechanism behind these results centers on retinal energy metabolism. The retina is rich in mitochondria, requiring substantial energy. The electron transport chain in mitochondria handles energy transformation. Two scenarios are described: shining red and infrared light on mitochondria versus blue light. - Blue light: Absorbed by porphyrins in the mitochondria, leading to the production of reactive oxygen species (ROS). Excess ROS reduce ATP production, diminishing energy available to retinal cells and impairing function. - Red and infrared light: Absorbed by cytochrome c oxidase and by nano water around ATP synthase. Absorption releases nitric oxide, allowing oxygen to enter and form water. The longer wavelengths are also absorbed by nano water around ATP synthase, reducing viscosity and enabling the rotor to run faster, generating more ATP and providing more energy for retinal cells to function properly. The speaker attributes the observed improvements to these mitochondrial light–energy interactions, particularly the enhanced ATP production from red and infrared light. A practical takeaway is proposed: add incandescent lighting to the environment.

German doctor Alexander Wunsch, a photobiology expert, explains the hidden dangers of modern lighting. With the shift to energy efficient LEDs, we’ve lost out on the health benefits that infrared radiation in traditional incandescent bulbs and candlelight used to provide. Infrared and near infrared light can penetrate as much as an inch into tissue, even through clothing. Unlike natural sunlight, LEDs lack the near infrared light that’s essential for cellular repair, especially in the eyes and mitochondria where energy is produced. Infrared light can actually produce energy in your cells. Overexposure to the blue wavelength of light emitted by LEDs can lead to serious health issues like macular degeneration, which is the number one cause of blindness as we age. It also blocks melatonin release. In addition, these LEDs flicker rapidly, which isn’t visible to us, but it can disrupt cellular function and impact our mental and hormone health. So Wunsch suggests sticking with warm, clear incandescent bulbs, the old fashioned kind, if possible, especially in the evening, and getting natural sunlight exposure during the day. Now it’s not practical to avoid LEDs altogether. He acknowledges that reality. But when you need LED lighting, don’t just buy the cheapest ones. Buy bulbs with a low flicker rate, a high CRI, and R9 values above 90 if you can, because those are closest to natural light. The Centric series by Waveform Lighting and the Sora Vivid a 19 at polarray.com are good choices.

Red light and infrared light can pass down into the deeper layers of our skin, where it can change the metabolic function of particular cells. Within the dermis, the deep layers of our skin, we have what are called sebaceous glands that actually make the oil that is present in our skin. So if you've ever had an infected hair follicle, that's not a coincidence that hair follicles tend to get infected. Part of it is because there's actually a portal down and around the hair follicle, but the sebaceous gland is where the oil is created that is going to give rise to, for instance, acne lesions.

Dosing considerations: "spectrum can I get? Then, how long should I do it? And then, how often?" "directly turn up the energy inside of your cells" "So your cellular respiration is going to speed up." "you can throw off a lot more oxidants, lot more free radicals. Pro oxidation." "they directly decrease the free radical buildup and the oxidative formation." "So you're getting the benefit of energy without the benefit of oxidation because the red light has taken care of that." "through those and some other means, are going to help the cell not only to kick start and to work faster, but you're going to help the cell to build up more healing capacity." "If you have a sick cell that is running slowly and the mitochondria in the cell are running slowly, it cannot heal like it ought to."

"Blue works by helping convert the red blood cells into a form that will properly carry and release oxygen." "It's believed to do this by increasing mitochondrial efficiency, powerhouse of our cells, and promoting the production of ATP." "Methylene Blue also shows promise as a powerful antioxidant, scavenging harmful free radicals and reducing oxidative stress, which is a key factor in aging and many, many diseases." "And lastly, perhaps its most groundbreaking property lies in its potential ability to significantly impact our mitochondrial health." "So Methylene Blue optimizes mitochondrial function, which not only boosts energy levels, but may also extend lifespan by ensuring our cells longevity." "Recent studies suggest its role in neuroprotection, showing its ability to preserve neurological function and protect against neurodegenerative diseases." "Its antimicrobial properties are also gaining attention, offering a potential avenue for treating antibiotic resistant infections such as Lyme disease."

Important music, you know, good music. You know music frequency affects the microbiome and we're going to show that in the future. Light affects the microbiome. You know is there certain light that basically calms you down? You know, lenses, when you're looking at lenses, right? You know, is there a lens, reflection of a light or a color that is more soothing than another. Know, mean there's Korkov so many out of Russia has some diagnostic tools that I think Joe Dispenza is using that's showing this kind of resonance. It almost looks like an EKG. We're so far on all that because right now this is all like gut feeling. And yes, that could be the way, but we need to scientifically show it. And we need to convince the physicians that are treating their patients that there's something to this science.