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On October 6, 2021, I met with my manager, Conwell Gill, a principal scientist at Pfizer. We discussed the ethics of giving people experimental booster shots for money. mRNA vaccines have been around for 50 years but never made it to clinical use due to side effects. Pfizer and Moderna used the emergency of the pandemic to push through their vaccines. Pfizer collaborated with Beyond Tech on mRNA technology for COVID-19. Everything was new and rushed due to the pandemic. There was no time to think, only to act.

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There is a new mRNA COVID-19 vaccine, but there is no evidence to support its effectiveness or safety in human trials. Additionally, several studies from different countries suggest that these vaccines may actually increase the risk of contracting COVID-19 over time. This is concerning and not a typical outcome.

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mRNA vaccines have shown the potential of cell and gene therapy. Two years ago, most people would have refused gene or cell therapy, but the pandemic has increased acceptance of innovative treatments.

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Every childhood vaccine will be mRNA, becoming gene therapies that alter genetics without re-approval. COVID vaccines were profitable data and experimentation tools, but the real danger is the continued genetic tinkering via mRNA integration into all vaccines. The speaker is now anti-vaxx and will not get any more vaccines for themselves or their family because all vaccines are being redesigned to include gene therapies, driven by profit.

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Our company is embracing cell and gene therapy, which has the potential to make a significant impact. The mRNA vaccines are a prime example of this. Just a couple of years ago, if we had asked the public if they would be willing to undergo gene or cell therapy, the majority would have refused. However, the pandemic has changed people's perspectives and made them more open to innovative solutions.

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- The m n r m r n a technology was a radical qualitative leap forward in technology. - The mRNA is a type of vaccine. - The reason it was called a scene was because was a brand name that had a track record of safety, and shoehorning it in that was one of the ways to make sure that people weren't terrified of the technology. - It bears very little resemblance to anything that went before that. - There are different types that they didn't have to contend with the fact that it wasn't the same technology. There are different technologies. - There certainly are. That are different technologies.

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All childhood vaccines will soon be mRNA-based gene therapies, without requiring reapproval. This means that getting any type of vaccine will alter a person's genetics. The focus is now on integrating mRNA into all vaccines, which raises concerns about tinkering with genes. The speaker strongly opposes vaccines and vows not to get any more, emphasizing the financial interests involved in this shift.

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Speaker 0 argues that billions of people were injected with an experimental vaccine, stating “it wasn't a bloody just no. It wasn't.” He rejects the notion of it being definitive or perfect, emphasizing that “it wasn’t” in terms of being a flawless solution. Speaker 1 counters, asserting “It was no one isn’t,” suggesting confusion or contradiction in the prior claim and challenging the certainty of the statement. He adds that there is a lack of a 100% success rate and questions the ultimate aim, asking what the core purpose is when it comes to giving your body a training of the immune system and technology. Speaker 0 reinforces the complexity, noting that there were “different types” to contend with and that the fact that they weren’t the same technology matters. He agrees there are various types of vaccines or approaches, indicating there is diversity in the technology or formulations used. Speaker 1 concedes the existence of different types and technologies, acknowledging that “there are different types of” vaccines, and that “There are different technologies.” He identifies mRNA as a type of vaccine but Speaker 0 interrupts, insisting “No. It was” and continuing his line of reasoning about the distinctions between the technologies and their evolution. Speaker 1 acknowledges change, saying “like this, and now it's like this,” recognizing a progression or shift in the approach. Speaker 0 rejects the suggestion that the transition is simple or uniform, insisting “No. No. No. It was like this, and now it's like this.” He asserts that the mRNA technology represented a radical, qualitative leap forward in technology, a claim about the significance of the development. Speaker 0 contends that naming the technology as mRNA can be acceptable only in a limited sense; he says “You can call it if if you want to, but it bears very little resemblance to anything that went before that.” The rationale for the term mRNA is tied to branding: “The reason it was called a scene was because was a brand name that had a track record of safety, and shoehorning it in that was one of the ways to make sure that people weren't terrified of the technology.”

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Two years ago, most people would have refused gene or cell therapy, but the pandemic has changed perceptions of innovation. The COVID vaccine is not a traditional vaccine as it doesn't provide immunity or prevent transmission. The Pfizer vaccine wasn't tested for transmission prevention before its release due to the urgency. Vaccinated individuals can still get COVID-19. Countries with rapid mass vaccination have seen increased infections and deaths. A study from the Cleveland Clinic suggests that the more shots received, the higher the risk of getting COVID. Vaccination puts evolutionary pressure on the virus, leading to mutations. Epidemiological analysis shows a significant number of deaths related to the vaccines, with dangerous mechanisms of action and consistency with other fatal conditions. Temporal relation is also evident, with many deaths occurring shortly after vaccination.

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Two years ago, most people would have refused gene or cell therapy, but the pandemic has changed that. mRNA vaccines are a prime example of this shift towards innovation in healthcare.

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We are working on developing new vaccines like TB and HIV using mRNA technology to make them high quality and low cost. Current COVID vaccines are not perfect, so we are working on new versions with longer-lasting protection for diseases like measles and tuberculosis. The mRNA technology also shows promise for cancer vaccines and rapid adaptation to future pandemics. We are even exploring using this technology for animal vaccines.

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When was the last time you saw a strand of DNA? It's the genetic code in almost every cell, defining who you are. Recently, there's been a rumor that COVID-19 vaccines alter your DNA. The Pfizer and Moderna vaccines use messenger RNA (mRNA) technology. After injection, the vaccine instructs your cells to prepare for an incoming virus, prompting your immune system to create antibodies. Importantly, the vaccine never enters the nucleus where your DNA resides, and once your cells use the vaccine, they destroy it. While these vaccines are new, mRNA technology has been in development for over a decade. So, if you're concerned about the vaccine changing your DNA, there's no need to worry. You remain unchanged.

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We are generating real-time data on mRNA vaccines, which have been in development for years due to side effects. Pfizer and Moderna used the pandemic to accelerate their development. The collaboration with BioNTech on flu led to the quick rollout of the mRNA vaccine. Clinical trials skipped phases, causing uncertainty. Concerns arise about vaccine distribution and the need for booster shots. Politics play a role in decision-making.

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The speaker suggests that prior to the pandemic, a survey asking the public about willingness to receive gene or cell therapy would have likely resulted in a 95% refusal rate. They believe the pandemic has opened people's minds to innovation in a way that was previously impossible, using mRNA vaccines as an example.

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I've been involved in over 50 vaccines, including mRNA vaccines. mRNA is like DNA, giving cells instructions to make proteins. This technology was originally for gene therapy, now used for vaccines. It's a new, experimental technology never used in humans before COVID. Animal studies were skipped for COVID vaccines, a novel approach.

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Making mRNA is easy and cheap, which is the key. In the next 5 years, advancements are possible with lipid nanoparticles and their self-assembly. This nano construction surpasses our technological expectations.

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The mRNA platform is effective but has a flaw: it can cause autoimmune disorders by producing foreign proteins in cells. The challenge is to target only specific cells and avoid damage to vital organs. The pandemic allowed the emergency use authorization of mRNA vaccines, bypassing safety measures. However, a large portion of the population has already accepted this technology. To address the issue, a solution could be to replace the spike protein with a different protein that doesn't have flaws. But if the problem lies in any foreign protein transcribed by cells, the immune system may still target vital organs.

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We are in a digital and scientific revolution, hacking the software of life with mRNA. Our body is made of organs, organs of cells, and in each cell is messenger RNA transmitting DNA information to proteins. This "operating system" can be altered to impact diseases like the flu and cancer. For instance, instead of injecting virus proteins for a flu vaccine, mRNA instructions can teach the body to make its own protection. This mRNA technology has vast potential for disease prevention and treatment.

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We discussed pandemic readiness and the speed of mRNA technology. I proposed a simulation to create a vaccine within 60 days, which was initially met with skepticism. However, due to our work on personalized cancer vaccines, we were prepared. When news of a new coronavirus emerged, we quickly got the sequence and began working on a vaccine. The conversation shifted to the need for disruptive entities to accelerate vaccine development, moving away from traditional methods like egg-based production. The urgency for innovative solutions to address outbreaks was emphasized.

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The emergency use authorization (EUA) was crucial for normalizing the mRNA platform, which was seen as a significant advancement in vaccine technology. The fear surrounding COVID-19 helped facilitate acceptance of this new approach, despite existing treatments that could have mitigated the pandemic's impact. If doctors had been allowed to explore effective treatments, the reliance on mRNA vaccines would have been diminished, creating a control group that could reveal potential harms. While the EUA was important, it wasn't strictly necessary; they could have navigated around it. The rollout of the mRNA platform aimed to reshape public perception, and the legal complexities surrounding the EUA provided a layer of immunity for those involved. The backlash and discussions about vaccine injuries may complicate future implementations of this technology.

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Using mRNA technology similar to that used for COVID, researchers are taking biopsies of a patient's cancer, extracting protein, and reintroducing it into the patient's cells. In clinical trials, 10,009 humans have been treated. All 10,009 are now cancer free. The researchers claim to have cured cancer.

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Nicholas Holcher, an epidemiologist and foundation administrator at the McCullough Foundation, appears on the WiderWake Media Podcast to discuss what he calls harms from the mRNA COVID vaccines and to critique mainstream approaches to the pandemic and public health policy. - Vaccine definitions and mRNA technology - Pre-2000 definition: a vaccine is an injectable or oral product that introduces a killed part of a virus or an inactivated form to the body so that encountering a wild-type version would not infect or would cause a less severe illness. - He asserts that mRNA injections are not vaccines: they are a gene transfer platform using modified messenger RNA with long persistence in the body (via N1-methylpseudouridine), delivered in lipid nanoparticles. He claims these bubbles distribute systemically, including to the brain, heart, bone marrow, and reproductive system, and that they instruct cells to produce a spike protein, effectively turning organs into “toxic spike protein production factories.” He says this leads to autoimmune attack on those tissues and contributes to adverse events, including myocarditis, strokes, immune destruction, and “turbo cancers.” - History and purpose of mRNA in vaccines - According to Holcher, work on this technology existed for decades but animals testing showed high mortality or sterilization in ferrets and mice, preventing approval except under a declared global emergency. He contends the COVID-19 crisis enabled emergency use authorization across Western countries, with ulterior aims to inject the globe with mRNA technology. - Global impact and uptake - He estimates about 70% of the global population received at least one COVID-19 injection (mRNA or viral vector). He notes Eastern countries used non-mRNA platforms (e.g., AstraZeneca/J&J in some places; Sinovac elsewhere) but that uptake in the West was high. - Harms and evidence - Excess deaths: cites a study by Dennis Brancourt et al. estimating around 17 million deaths worldwide as a result of COVID injections (as of September 2023); he claims US deaths could be in the hundreds of thousands to millions. - Turbo cancers: cites multiple studies in 2023 showing increased risk of seven cancer types (colorectal, bladder, breast, thyroid, prostate, etc.) in vaccinated groups; cites a major cancer journal, OncoTarget, reporting hundreds of turbo cancer cases across 27 countries, with Pfizer contributing most cases. Holcher also mentions his own group’s work with Neo7 Bioscience documenting genomic integration of vaccine-derived mRNA in a stage IV bladder cancer patient (31-year-old woman) with a segment of mRNA found in circulating tumor DNA on chromosome 19; another study reported thousands of dysregulated genes in post-vaccine cancers, including p53, KRAS, and BRCA. - Definition of turbo cancer: per Merrick et al., rapid, aggressive tumor progression with sudden onset and early metastasis, often in younger individuals, and resistant to treatment. - Fertility, pregnancy, and autism - Fertility: cites studies suggesting fertility impacts, including Karaman et al. finding depletion of primordial follicles in rats after mRNA vaccination; Manichi et al. reporting 33% lower conception rates in vaccinated women in Denmark; a study indicating a ~20% drop in sperm concentration and motility with no recovery over five months. - Autism: asserts a large body of evidence linking vaccines to neurodevelopmental disorders, citing a 136-study review with 107 studies finding positive associations between vaccines and neurodevelopmental issues, including autism, attributed to toxicity and immune system disruption, particularly in children with high vaccine exposure and reduced detox capacity (CYP450 impairment). - Other topics tied to vaccines and public response - The COVID-19 period and vaccine skepticism: claims the pandemic catalyzed a large anti-vaccine movement because people were compelled to take an experimental gene therapy product. - Sam Altman and gene editing: discusses Altman’s Preventive venture with the aim to reduce heritable diseases via in utero gene editing but warns of the path to designer babies and the potential for harm in early-iteration edits, citing prior CRISPR experiments on human embryos that produced deformed offspring or nonviable results. - AI, workers, and future society: predicts two-tier society with implanted or enhanced individuals and a replacement of human labor by robots and AI systems; discusses military and surveillance ambitions in gene editing and AI augmentation. - Mental health and digital life: references a randomized trial showing that turning off mobile Internet improved depression scores and well-being to an extent comparable to or greater than antidepressants. - World Health Organization (WHO): notes the US has pulled out of the WHO, arguing this is good for the US but potentially harmful for others still in the organization; expresses concerns about the pandemic treaty and ongoing global health governance, including vaccine passport-style surveillance. - FDA and public health policy: acknowledges some shifts (e.g., cutting doses from the childhood schedule) but argues the FDA remains compromised and too aligned with vaccine industry interests; criticizes the removal of a potential black box warning for vaccines and calls for more accountability. - Resources and contact - Holcher invites listeners to follow him on X (Twitter) at @nichulsher and to read their work on focalpoints.com and through McCullough’s network. Note: The transcript presents Holcher’s claims and interpretations about vaccines, turbo cancers, autism, fertility, and policy changes. The summary reproduces these points without endorsement or evaluation.

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In a 2016 interview, the CEO of Moderna emphasized the importance of using lipid nanoparticles to deliver RNA molecules effectively. However, repeated doses of these nanoparticles can lead to dangerous side effects, as seen in past abandoned technologies by big companies like Merck and Novartis. The difficulty of getting RNA into cells without causing harmful side effects was also highlighted.

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Our company is embracing cell and gene therapy, which has the potential to make a significant impact. mRNA vaccines are an example of this type of therapy. Two years ago, if we had asked the public if they would be willing to undergo gene or cell therapy, the refusal rate would have been around 95%. However, the pandemic has made people more open to innovation in ways that were previously unimaginable.

TED

How mRNA Medicine Will Change the World | Melissa J. Moore | TED
Guests: Melissa J. Moore
reSee.it Podcast Summary
Messenger RNA (mRNA) vaccines are safe and effective, providing instructions for the body to protect against SARS-CoV-2. mRNA technology is revolutionizing medicine, enabling treatments for previously untreatable disorders by instructing the body to produce necessary proteins. Each of the 30 trillion cells in the body contains billions of proteins, essential for various functions. Current clinical trials are exploring mRNA applications for metabolic diseases, personalized cancer vaccines, and regenerative medicine. The rapid production capabilities of mRNA allow for quick responses to emerging diseases, with potential for combination vaccines targeting multiple viruses.
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