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The Zembla investigation reveals that the scientific evidence for the treatment of transgender youth is insufficient. Concerns also exist regarding the impact of treatment on brain development, with research on this topic being announced seventeen years ago but never conducted. Puberty blockers are used to pause puberty in children with gender dysphoria, allowing time for reflection before irreversible hormone treatments and surgeries. However, the effectiveness of these blockers is questioned, and their potential effects on brain development remain unknown. Limited research suggests that they may influence brain development, but the implications for adolescents are unclear. Further research is needed to provide clarity and inform decision-making for transgender youth.

- "Puberty blockers are a group of medications or hormones that we use in the transgender population to stop puberty from progressing." - "We call them in endocrinology gonadotropin releasing hormone analogs or agonists." - "Their job is to really interfere with the signaling from the brain to either the ovaries or the testicles that produce the hormones." - "When somebody starts puberty, we can use them to stop the puberty from progressing, thereby allowing somebody to really explore their gender without the pressure of having secondary sex characteristics that are often permanent." - "And the really nice thing about puberty blockers is that they are reversible, so it's a really nice way for an adolescent to be able to explore their gender." - "We like to use them in birth assigned males who have already even gone through a full male puberty because they are able to then use a lower dose of estrogen."

Vultures profit from the confusion they intentionally create in innocent kids' minds. They use puberty blockers, which are also given to sex offenders, to chemically castrate them. Many kids undergo surgeries like double mastectomies before turning 18. Children in identity crisis need love and guidance, not hormone injections and scalpels. Adults must protect our kids because their silence makes them complicit in what's happening. The media blindly accepts the medical establishment's claim that castrating a child is life-saving care without questioning it. We must protect our kids.

In 2016, participants in an early intervention study had been on puberty blockers for a year. Results showed no change in psychological well-being. Despite this, JIDS continued to refer under 15s for blockers without solid data to support it. The findings were not published until 5 years later.

Max, who identifies as a boy, is visiting the doctor to discuss hormone blockers to prevent puberty. He has started experiencing some breast growth and feels uncomfortable. His parent expresses concern about medical interventions and their effects on bone health and psychosocial development. The doctor explains that hormone blockers can halt puberty progression and reassures that if Max changes his mind, he can still go through female puberty later. The procedure involves inserting a small implant in Max's arm, which will last about 14 to 18 months. The entire process is quick, taking only about 10 to 15 minutes.

Puberty blockers are drugs given to children who wish to transition genders, halting their natural development. This practice can lead to lifelong dependency on hormones and sterilization, raising concerns about child welfare. The conversation touches on whether children can truly understand the implications of such decisions at a young age. One perspective argues that gender identity is a personal choice, while the opposing view emphasizes the importance of biological reality. The discussion highlights the risks of affirming a child's desire to transition without addressing underlying mental health issues. Ultimately, it questions the morality of medical interventions on minors, advocating for a more cautious approach that respects the complexities of gender identity and the well-being of children.

When a child experiences gender dysphoria, there is a disconnect between their feelings and the gender assigned at birth. This issue is serious, as transgender adolescents have a significantly higher suicide rate—almost eight times that of their cisgender peers. The AAFP's focus on drugs, hormones, and surgical interventions, rather than a more conservative approach like psychotherapy, is concerning. This approach is seen as unethical and inappropriate, highlighting the need for a broader perspective on treatment options.

"For someone who is assigned male at birth and if they've already been through puberty, they could produce a semen specimen and have it frozen." "If someone is assigned female at birth and they are also all the way through puberty, you can do egg banking, which entails a little bit more." "Typically, you have to take some additional hormone injections and it's a procedure to go in and retrieve the eggs." "We think someone has to be probably in mid male puberty to produce semen." "There have been some case reports of transgender men who were assigned female at birth who weren't completely through puberty and have been able to do fertility preservation, but we don't know if that applies to everybody." "We definitely counsel all of our patients about fertility preservation." "Usually from their first visit, we're starting to talk about it."

The ovary doesn't produce estrogen anymore and the testicle doesn't produce testosterone. Thus, the signs that we see from these hormones are blocked and don't progress in puberty. The main benefit is that they prevent the unwanted permanent effects of puberty, and thus future surgeries can be avoided as an adult. We can prevent the need for any chest reconstruction in affirm trans males or facial feminization surgery in transfemales. They are also reversible, and thus if the patient decides to stop using pubertal blockers, their endogenous puberty will resume as previous. Using pubertal blockers can alleviate the depression or worsening gender dysphoria that is often associated with progressing pubertal changes. And lastly, the use of puberty suppression is recommended by the Pediatric Endocrine Society in their clinical guidelines for the treatment of transgender and gender diverse youth.

"The eligibility for getting gender affirming surgeries at Boston Children's Hospital is basically the same as it would be for most other hospitals or surgeons in The United States." "And that's the case because we all follow the World Professional Association for Transgender Health or WPATH standards of care." "For top surgery, you are requested, but not required to have been on gender affirming hormones for at least a year." "If you're a trans woman, it's really encouraged that you be on estrogen for at least a year because you want to maximize your natural breast growth." "Many surgical centers require you to be 18." "At Boston Children's Hospital for top surgeries, we'll see people as young as age 15 if they've been affirmed in their gender for a long period of time and don't really have any other life complications that make surgery inappropriate."

The speaker discusses the standards applied to children and the potential benefits of going on blockers. They mention that blockers can prevent the development of a deep voice, Adam's apple, and facial hair. The speaker shares their personal experience of spending $5,000 on facial hair removal and $25,000 on facial feminization surgery. They believe that blockers can prevent the need for such procedures and alleviate stress.

Doctor Olsen faced a decision regarding Josie's treatment. She advised starting hormone blockers around age 13, ensuring Josie wouldn't have to wait until 16 to begin. Josie received the blockers as an implant in her arm, showing great bravery as she embraced this new chapter in her life. The doctor reflected on how, just twenty years ago, such treatment wouldn't have been possible, and Josie would have faced male puberty, which was a terrifying thought. The doctor expressed relief that they could provide this support now, emphasizing the importance of the decision for Josie's well-being.

An endocrinologist questions the use of powerful hormones and surgeries in gender affirmative therapy without concrete evidence of gender identity. They highlight the high rates of desistance in children with gender dysphoria and the lack of objective markers to determine if a child will persist in their gender identity. The Endocrine Society acknowledges the low quality of evidence and the difficulty in identifying which children require treatment. The American Academy of Pediatrics suggests asking the children themselves. The spread of the affirmative model of care has outpaced the evidence supporting it, as shown by systematic reviews indicating poor quality and uncertain benefits. A study on mastectomy in youth is criticized for drawing conclusions based on a small sample size and short follow-up period. The quality of research in this field is questioned.

Concerns arise about the influence of pharmaceutical companies on psychiatric diagnoses, particularly regarding child dysphoria. Children, who are not allowed to make significant decisions like getting tattoos or drinking alcohol, are being encouraged to change their gender. Studies on puberty blockers indicate they do not improve mental health and may have severe side effects, yet this information is not being published. There seems to be a cultural trend among certain demographics, particularly affluent white progressives, where identifying as trans becomes a social signifier. This shift may lead parents to rationalize their child's gender identity as a way to engage with social issues. Normal adolescent confusion is being medicalized, risking irreversible consequences for children who may later regret their decisions.

Michigan Medicine strives to be a safe, welcoming place for transgender individuals and to provide excellent health care regardless of gender. The goal of this video is to improve the comfort and competency of frontline staff in caring for transgender individuals. We will start by talking about gender identity, challenges the transgender community has faced in the health care system, and Michigan's policies regarding gender non-discrimination. The second half of this training is job specific. To discuss gender identity, it is important to understand the difference between sex and gender. Sex refers to one's reproductive organs, native hormones, and chromosomes, while gender identity refers to one's internal sense of gender, a person's basic sense of being a man or boy, a woman or girl, or another gender. Gender identity can be expressed by how individuals present themselves socially, including clothing, physical characteristics, speech, and mannerisms. All people, whether they are transgender or cisgender, meaning not transgender, have a gender identity and expression. Transgender is a term for individuals whose gender identity differs from the gender identity typically associated with their sex assigned at birth. There are many identities that fall under the umbrella of transgender. Transgender men, trans men, or trans masculine refer to people who are assigned female sex at birth but identify as men or masculine. Transgender women, trans women, or trans feminine refer to people who were assigned male sex at birth but identify as women or feminine. Other individuals may identify as genderqueer, agender, genderfluid, two spirited, bigender, or another identity that does not fit neatly into the categories of men or women. All major American medical societies, including the American Medical Association and American Psychological Association, endorse gender affirming care as the standard of care for transgender individuals. This means caring for people in a way that supports their gender transition and gender identity. Transgender people may undergo any one of a number of gender affirming medical interventions, including hormonal therapies like estrogen, testosterone, or hormone blockers, and surgical treatment to change body contours or genitalia. However, it is important to note that one does not have to undergo any medical or surgical treatment to be transgender. Some people are easily read as the gender they affirm while others are visibly gender non conforming or androgynous appearing.

Beauty blockers have been used by doctors for kids experiencing precocious puberty. The conversation then shifts to transgender children, with one speaker arguing that gender affirming care is life-saving and reduces suicide rates. The other speaker questions the lack of studies on suicide rates among transgender children and argues against medical interventions like hormone therapy and surgeries. The conversation becomes heated, with one speaker claiming that transgender children don't exist and that they should be accepted as they are, while the other argues that they need medical interventions. The debate centers around the belief that transgender children are either born in the wrong body or that they should be accepted without medical interventions.

I often see youth who have already undergone medical interventions due to a backlog in mental health support. Children may not fully understand the impact of these interventions, making it challenging to discuss. It can be especially difficult for young adolescents starting puberty suppression. We aim to make kids happy in the moment, but it's crucial to consider the long-term effects on their development. This is a growing challenge in our field that requires further exploration.

If you're transgender or nonbinary and feel uncomfortable with your puberty experiences, you're not alone. Puberty blockers can temporarily halt the changes caused by hormones like testosterone and estrogen, giving you more time to figure out your gender identity. It's okay to not have all the answers right now, as understanding yourself takes time. Talking to a trusted adult, nurse, or doctor can be helpful. To learn more, visit plannedparenthood.org/teens.

Beauty blockers have been used by doctors for children experiencing precocious puberty. The conversation then shifts to transgender children, with one speaker arguing that gender affirming care is life-saving and reduces suicide rates. The other speaker questions the lack of studies on suicide rates among transgender children and challenges the necessity of medical interventions such as hormone therapy and surgeries. The conversation becomes heated as they discuss the cutting off of body parts and the speaker's belief that there is no such thing as a transgender child. The debate centers around the message being sent to children and the potential harm or benefit of gender affirming care.

Karen Selva, pediatric endocrinologist and medical director of Randall Children's Hospital T Clinic, discusses puberty blockers for transgender and gender expansive youth. Puberty blockers work at the level of the pituitary gland and they actually suppress the release of the LH and the FSH so that the sex organs are no longer stimulated; The signs are blocked and don't progress. The main benefit is that they prevent the unwanted permanent effects of puberty, and thus future surgeries can be avoided as an adult. We can prevent chest reconstruction in affirm trans males or facial feminization surgery in transfemales. They are reversible; if stopped, endogenous puberty resumes. They can alleviate depression or worsening gender dysphoria. The Pediatric Endocrine Society recommends puberty suppression in clinical guidelines for transgender and gender diverse youth. The practice is new; first guidelines were published in 02/2009, and long-term data are not yet available.

The Jits team learned that children's well-being did not improve with puberty blockers, and all who were old enough continued to hormones. This raised concerns about blockers not providing time to think but rather starting a pathway. Only 1% of young people stopped treatment. There are questions about why none stopped once they started, suggesting either not enough young people were being considered or the treatment itself could have an impact. Despite evidence showing blockers weren't effective for many young females, there was no significant change in the service's approach.

In 2021, a study found no significant changes in mental health or gender dysphoria among children on puberty blockers. A recent reanalysis showed that after 12 months, 34% had worsened, 29% improved, and 37% stayed the same. The original study lacked a control group, so causation couldn't be determined. Blocking puberty may ease future gender transition, but this wasn't the focus of the study. The key lesson is to adapt practice when new evidence emerges.