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Many people are vitamin D deficient, leading to increased risks of depression, Parkinson's, Alzheimer's, and cancer. Supplementing vitamin D alone won't help if you're eating poorly, not exercising, smoking, or drinking excessively. However, in an otherwise healthy lifestyle, correcting low vitamin D can make a big difference. It's important to consider context, as magnesium is crucial for converting vitamin D into its active form. About 50% of people don't get enough magnesium from sources like dark leafy greens, pumpkin seeds, dark chocolate, and almonds. Stress, coffee, alcohol, and sugar deplete magnesium levels. Magnesium is an anti-aging macro-mineral involved in DNA repair enzymes.

Vitamin D absorption depends on magnesium; without magnesium, vitamin D cannot be absorbed. Conversely, vitamin D aids magnesium absorption. Many people are deficient in both vitamin D and magnesium. Magnesium deficiency can lead to calcium deposits in joints and arteries. Therefore, vitamin D supplements should include magnesium and other cofactors.

Vitamin D's effectiveness relies on magnesium. Vitamin D supplementation can worsen a magnesium deficiency because it increases the body's magnesium requirement. Vitamin D and magnesium work synergistically. Vitamin D toxicity, marked by excessive blood calcium, can be mitigated by magnesium, which prevents vascular calcification. Magnesium functions as a natural calcium channel blocker, and it helps regulate blood clot formation, which can be caused by excessive calcium.

The most crucial nutrient for the human body is vitamin D3, often deficient but easily fixed. Take at least 5,000 IUs of vitamin D3 with 120-140 micrograms of K2, preferably MK-7 for better absorption. This combination helps calcium go to the bones instead of the arteries, reducing risks of high blood pressure, heart disease, congestive heart failure, peripheral artery disease, stroke, and heart attack.

Vitamin K2, found in foods like hard cheeses, red meat, butter, egg yolks, and liver, is critical for clearing plaque out of arteries. These are foods people are often told to avoid. Vitamin K2, originally called Activator X, was discovered by Dr. Weston A. Price. Traditional cultures that ate diets rich in animal foods got 10 times the amount of vitamin K2 and were in nearly perfect health. Vitamin K2 takes calcium out of the arteries and puts it into the bones and teeth. This benefit is specific to vitamin K2 found in animal foods; vitamin K1 from plant foods doesn't have the same effect.

Osteomalacia involves bones becoming very soft, possibly occurring on a massive scale subclinically. The speaker believes they had it in high school due to poor diet and vitamin D deficiency, leading to fractures. In osteomalacia, certain proteins don't develop well. Vitamin D controls calcium absorption by 20 times in the small intestine. There are two vitamin D systems: one controlling calcium and another that is non-calcium related. A vitamin D blood test will likely show a level of 30 or less, indicating the need to take vitamin D3.

Vitamin D3 supplementation is associated with a 40% reduced risk of dementia, likely by preventing deficiency. Studies involving dementia and Alzheimer's patients showed that vitamin D supplementation improved cognition and lowered markers of amyloid plaques compared to a placebo. Vitamin D regulates 5% of the protein coding human genome.

Magnesium activates vitamin D, which must be in its active form to work. Vitamin D3 boosts calcium absorption. Vitamin K2 then directs the increased calcium from the blood vessels into the bones. Magnesium, vitamin D3, vitamin K2, and calcium are all essential nutrients. Sufficient intake of these nutrients through diet and lifestyle is necessary for proper bodily function, including maintaining bone strength.

Vitamin D is important; take at least 10,000 IUs, but for chronic problems, take 20,000-40,000 IUs. When taking vitamin D3, take K2 simultaneously to prevent calcium buildup in the arteries. K2 drives calcium from the blood and joints back into the bone, protecting against hypercalcemia. The ratio is 10,000 IUs of vitamin D3 to 100 micrograms of K2. If increasing D3 to 20,000 IUs, then take 200 micrograms of K2.

Vitamin D3, a neurosteroid produced in the brain from sunlight, may protect against neurodegeneration. Every major brain area has vitamin D receptors, including those for memory and mood. Harvard studies are using high-dose vitamin D for depression. These receptors control over 900 genes related to brain health. Low vitamin D levels may increase cognitive decline risk by 290%. Research indicates optimal D3 levels protect against depression, dementia, and brain aging. The brain will take vitamin D from other tissues if levels are low. Have vitamin D levels tested, aiming for 75-100 ng/mL. Take 5,000-7,000 IU of D3 daily with vitamin K2 for optimal absorption and brain benefits.

About 80% of people are deficient in vitamin D, which can lead to various health issues like depression, Parkinson's, Alzheimer's, and cancer. However, simply taking vitamin D supplements won't help if you have an unhealthy lifestyle. If you clean up your lifestyle and still have low vitamin D levels, it can make a big difference. It's important to note that even if you spend a lot of time in the sun or take vitamin D supplements, without adequate magnesium in your diet, the enzymes that convert vitamin D into its active form won't function properly. Unfortunately, 50% of the population doesn't consume enough magnesium, which can be found in dark leafy greens, pumpkin, dark chocolate, and almonds. Magnesium is crucial for DNA repair enzymes and has anti-aging properties.

"The secret to antiaging? It shouldn't cost a billion dollars. It's the cheapest form of vitamin d." "Harvard backed randomized control trial, the gold standard when evaluating if something works, where over a thousand adults were followed for four years." "And what they showed is vitamin d three slowed telomere shortening, aka biological aging, by nearly three years." "We take two thousand to max four thousand IUs of vitamin d three a day." "But it's important that we marry this to vitamin k two so that that calcium ends up in our bones and not our arteries." "Last, magnesium, because your body cannot activate vitamin d three without it." "And the best part of this study, the authors had zero conflicts of interest. Nada, Zip, Zilch. Just pure science." "Let me know if you guys have any questions below."

Vitamin K2 helps prevent calcium buildup and drives calcium into bones and teeth. Vitamin A, specifically retinol, is another important nutrient cofactor for Vitamin D3. Vitamin A receptors sometimes bind with Vitamin D receptors, and both work together. A deficiency in one can affect the other's optimal function. Vitamin A also helps keep calcium out of arteries. Vitamin A deficiency symptoms include difficulty seeing in the dark, dry eyes and skin, a lowered immune system, and acne.

Low-fat products should be avoided because they lack vitamin K2, a crucial nutrient, especially as we age. Vitamin K2, found in fatty cheese and goose liver, is essential for bone health. It helps solidify bones by removing calcium from arteries and preventing calcium buildup in joints, which can cause arthritis. For those with calcium in the arteries and joints, leading to stiffness, a high-dose vitamin K2 supplement may be beneficial.

Vitamin D deficiency increases the risk of cancer, and taking vitamin D can prevent cancer. It is also effective for treating depression and important for the immune system. Big pharma dislikes vitamin D because it reduces the risk of many diseases. Studies on vitamin D are often designed to fail using low doses. Higher doses are recommended for those with chronic inflammation or autoimmune diseases. The sun is beneficial and avoiding it increases the risk of dying. Sunshine also prevents cancer, including melanoma. Spending about 30 minutes in the sun without sunscreen is recommended, as sunscreen may increase the risk of melanoma.

Vitamin D should always be taken with vitamin K2. Vitamin D3 increases calcium absorption, potentially leading to high blood calcium levels, which can be problematic. Vitamin K2 directs calcium from the blood into the bone, preventing soft tissue calcification in areas like arteries and joints. The recommended ratio is 100 micrograms of vitamin K2 for every 10,000 IUs of vitamin D3.

Vitamin D3 is popular, but I advise against it. It's made from rat poison's active ingredient, causing hypercalcemia. Big pharma profits more from vitamins than drugs. Pfizer's investment led to a 90% deficiency rate. D3 is made from radiated sheep's wool and toxic chemicals, then added to GMO soybean oil. The sun is better than a pill. Share natural ways to boost vitamin D for a free guide.

Vitamin D is crucial; take at least 10,000 IUs, or more (20,000-40,000 IUs) for chronic issues. When supplementing with Vitamin D3, it's important to take Vitamin K2 simultaneously, especially regularly, to prevent calcium buildup in the arteries. Vitamin K2 directs calcium from the blood and joints back into the bone, counteracting the hypercalcemia risk associated with Vitamin D toxicity. The recommended ratio is 10,000 IUs of Vitamin D3 to 100 micrograms of Vitamin K2.

Vitamin D absorption relies on magnesium; without magnesium, vitamin D cannot be absorbed. Conversely, vitamin D aids in magnesium absorption. Many people are deficient in both vitamin D and magnesium. Magnesium deficiency can lead to calcium deposits in joints and arteries. Therefore, vitamin D supplements should include magnesium and other cofactors.

Eighty-five percent of the world's population is clinically deficient in vitamin D3, a nutrient humans make from sunlight and cholesterol. Vitamin D3, or cholecalciferol, is arguably the most important nutrient in the human body. People have been taught to fear the sun, but most are not getting enough. The rise in skin cancer incidence is superimposable with the use of sunscreen. Since 2018, multiple brands of sunscreen have been pulled from the market for directly causing skin cancer.

Megan Kelly opens with topics including Congresswoman Jasmine Crockett’s potential Senate bid and an alleged Republican push to recruit her, plus a clarification about Golden Globes “snub” coverage. She previews longevity expert Gary Breka as a second-hour guest and briefly plugs Andrew Klavan, host of The Andrew Klavan Show, inviting listeners to subscribe and highlighting Peak wellness products and a Sun Goddess Matcha offer. Andrew Klavan joins Megan to discuss Hollywood’s value system and the Golden Globes’ new category for best audible podcast. Megan explains that some voters must be courted by Golden Globes organizers to qualify for nomination and recalls that her team withdrew their name to avoid the dog-and-pony show. She notes she never sought the award and that, despite top podcast rankings, they refused nomination. Klavan agrees, adding that he never expected nomination and recounts his experience after writing Empire of Lies, describing a moment in which he realized he would likely not win further awards. He describes his own left-leaning critics and reviews and discusses the broader challenge conservatives face in achieving recognition within the arts. Klavan reflects on the broader impact of awards and the arts, comparing the entertainment world to sex in terms of long-term spiritual influence. He argues that the right has not built the same cultural infrastructure to celebrate and study the arts as the left dominates it, citing examples of left-leaning award outcomes and left-wing content that receives recognition. He contends that Hollywood’s “fake god” status and the way awards are used can influence careers, and he contrasts this with conservatives’ willingness to engage with the system. He recounts his own Hollywood career decline due to political positions and stresses the importance of integrity and fearlessness in speaking one’s mind, even at personal cost. Megan agrees, noting her stance of not seeking acceptance from Hollywood and the corrosive nature of blurring lines between journalists and entertainment elites. The discussion turns to contemporary industry examples, including Met Gala chair selections and celebrity appearances, with Megan criticizing the relevance of chair choices and highlighting celebrities’ perceived decline in cultural prominence. Klavan remarks on Sidney Sweeney’s recent messaging shifts, the pressures from agents and industry gatekeepers, and the broader risk for young conservatives in Hollywood. They discuss actors who have faced career consequences for their beliefs, referencing Zachary Levi’s claims of being gray-listed and the broader risk to conservative artists in the industry. The conversation touches on high-profile figures like Tom Stoppard and Cormac McCarthy as examples of conservatives in the arts, and they reflect on whether the industry’s power and influence are being wielded to push a left-leaning agenda. Megan shifts to a segment about Jasmine Crockett’s Senate bid, noting NOTUS’s report alleging an astroturf recruitment process by the National Republican Senatorial Committee to push Crockett into the race, and that Crockett’s announcement caused Colin Allred to drop out. They discuss Beto O’Rourke and Joaquin Castro vs. Crockett, and the idea that Republicans might have orchestrated Crockett’s bid to defeat a stronger Democrat opponent. They consider the potential consequences and the political dynamics in Texas, with the panelists acknowledging strategic risk but generally viewing the tactic as a savvy play. They critique media and political dynamics, including public reactions to Crockett’s campaign launch, the use of a rapper at her rally, and various congressional personalities described as “crazy women” by some. They debate the complexity of party strategies and how media coverage shapes voter perception, with the conversation highlighting perceived inconsistencies in how media treats different political actors. As the program moves into a commercial break, Megan announces a segment by Gary Breka, a longevity expert and founder of The Ultimate Human, who has worked with Dana White, whom Breka credits with significant health transformation after a personal blood test projected a longer lifespan. The program teases the guest appearance and announces Breka’s discussion topics. The interview with Gary Breka begins, with Megan asking for a synthesis of Breka’s eight tips and the special elements that helped Dana White move from a CPAP-dependent, drug-reliant regimen to feeling like he’s in his twenties. Breka explains the core principles: sleep mastery, a whole foods diet, and non-negotiable mobility, arguing these three are foundational and that no other strategies matter if these aren’t in place. He emphasizes that long-lived populations (Blue Zone studies) achieve health through no processed foods and consistent physical activity, not adherence to any single diet. Breka argues that supplements are appropriate when used to address specific deficiencies uncovered by testing rather than as universal cures. He underscores the importance of nutrient refinement over generic supplementation and explains that genetic methylation testing can identify which nutrients the body can convert into usable forms, guiding targeted supplementation. He uses Dana White as a case study to illustrate how specific gene mutations (including MTHFR) can affect nutrient metabolism and disease risk, such as hypertension linked to homocysteine elevation when conversion of folic acid is impaired. The discussion covers vitamin D3 (cholecalciferol) as a crucial nutrient, noting widespread clinical deficiency and recommending 5,000 IUs daily, paired with vitamin K2 to aid calcium deposition in bones rather than arteries. Breka explains how vitamin D3 interacts with immune function and cites COVID data linking deficiency to morbidity. He advocates for outdoor sunlight exposure while acknowledging practical considerations in colder climates, recommending supplementation when sun exposure is limited. Breka also addresses gut health, tryptophan-to-serotonin conversion, and the interplay between gut function and anxiety, explaining how methylfolate deficiency can manifest as gut motility problems and mood disorders. He discourages relying on broad online supplement searches, urging consultation with a physician or trusted sources, and points listeners to his website, theultimatehuman.com, for more resources and a VIP group offering private Q&A and even an AI assistant for dietary and supplement planning. Megan and Andrew discuss sleep timing, vitamin D3 dosing, and the challenges of obtaining sunlight in northern climates, with Breka advising a combination of sun exposure and supplementation. They touch on circulation and the role of vasomotor activity in overall health, and emphasize the importance of minerals and trace elements for bone health, arguing that calcium alone is insufficient and that regular loading and mineral intake are necessary for bone strength. The program closes with Breka summarizing the three core priorities (whole foods, sleep mastery, mobility), the value of genetic methylation testing, and resources available at TheUltimateHuman.com. Megan thanks Breka and teases returning guests and future topics. She hints at further exploration of health fundamentals, reflecting on the day’s discussions about aging, nutrition, and elite performance. She invites listeners to visit the website and teases the next show with Real Clear Politics and a special appearance by Doug Brunt.

- I talk a lot about vitamin D but I wouldn't recommend taking vitamin D by itself. - I would always take vitamin K2 with vitamin D because vitamin D3 increases calcium absorption in your intestines by 20 times and that ends up in the blood so you can have a lot of calcium in the blood which can be a problem for people especially if they're prone to kidney stones or arthritis but vitamin k two comes to the rescue and that takes the calcium from the blood and pushes it into the bone. - One of the really important things that vitamin K2 does is to prevent soft tissue calcium from accumulating. - That could be in your arteries or the joints or any organ. - So to protect you against any potential side effects of vitamin D3, make sure you take vitamin K2 at the same time. - And as far as the ratios go, for every ten thousand IUs of vitamin d three, take a hundred micrograms of vitamin k two.

Vitamin D absorption relies on magnesium; without enough magnesium, vitamin D cannot be absorbed. Conversely, vitamin D aids in magnesium absorption. Many people are deficient in both vitamin D and magnesium. Magnesium deficiency can lead to calcium deposits in joints and arteries. Therefore, vitamin D supplements should include magnesium and other cofactors.