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Turmeric, a powerful herb used for centuries, has numerous potential health benefits. The strongest evidence supports its use in treating joint pain and osteoarthritis, with turmeric extract showing similar effectiveness to NSAIDs but with fewer adverse events. Turmeric also shows promise in improving metabolic health, insulin resistance, and glucose control. It has been found to lower fasting blood glucose, hemoglobin A1c, and insulin resistance in studies. Additionally, turmeric supplementation has shown positive effects on fatty liver disease. When choosing a turmeric supplement, it is important to consider factors such as absorption and third-party testing. Curcumin, the active compound in turmeric, should be taken with piperine and with meals containing fats or oils for optimal absorption. While generally safe, curcumin can cause gastrointestinal issues and has interactions with certain medications. It is not recommended for those with kidney or gall stones, and caution should be exercised during pregnancy or breastfeeding. Further research is needed to explore the potential benefits of turmeric in other conditions.