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There has been a significant return on investment, but it's not as high as claimed. Vaccinated individuals are protected against COVID-19 and its variants, reducing transmission and allowing society to return to normal. Getting both vaccine shots is crucial. Vaccinated people are unlikely to get infected, be hospitalized, or die from the virus. They can participate in activities without masks or distancing, but they can still transmit the virus. Vaccines slightly reduce transmission, but a new approach is needed. Israel's experience suggests a potential need for booster shots. The plan is for every adult to receive a booster shot. Overall, it has been a great investment.

Pfizer reported its vaccine shows 95% efficacy, but this refers to relative risk reduction, not overall risk reduction. In Pfizer's trial, 8 out of 18,198 vaccinated people developed COVID-19. In the unvaccinated group, 162 people contracted it, meaning the risk without the vaccine was 0.88%, reduced to 0.04% with the vaccine. The absolute risk reduction is 0.84%. The 95% figure refers to the relative difference between 0.88% and 0.04%. Relative risk reduction is considered misleading, and the FDA recommends using absolute risk reduction instead. The question is raised how many people would have taken the vaccine knowing it offered less than 1% benefit. In Canada, any potentially serious risk must be disclosed.

Vaccines are seen as magical but expectations should be tempered. Pfizer's vaccine is 95% effective, but efficacy drops over time. Boosters may be needed annually. Moderna is working on a combined flu and COVID vaccine. The future is uncertain, but we must adapt.

The AstraZeneca vaccine is 100% effective against hospitalization and death, a crucial statistic that needs more attention. This information has only recently become available, and while the 70% effectiveness rate is also impressive, the focus should be on the strong protection it offers against severe outcomes.

There is a new mRNA COVID-19 vaccine, but there is no evidence to support its effectiveness or safety in human trials. Additionally, several studies from different countries suggest that these vaccines may actually increase the risk of contracting COVID-19 over time. This is concerning and not a typical outcome.

Vaccination is crucial for protecting oneself and others, and for society to return to normal. Vaccinated individuals are less likely to transmit the virus or get sick. Getting vaccinated and receiving booster shots can save lives and prevent the spread of infection. The goal is to become a dead end for the virus, stopping its transmission. Vaccinated people do not get infected and cannot be used as hosts to spread the virus. However, the initial emergency use authorization did not have sufficient data on the vaccine's effect on transmission. The speed of scientific progress necessitated quick action.

The speaker acknowledges that the vaccine did not completely stop the spread or infection, but clarifies that initially it did for the Wuhan strain and the alpha strain. Early data and literature published in the New England Journal showed that those who were vaccinated and didn't get infected were not transmitting the virus to others. The vaccine had a high efficacy of up to 96% early on and this efficacy did not change over time.

Thank you, Senator Canavan. Did Pfizer test if the COVID-19 vaccine could stop or reduce virus transmission before its late 2020 approval? To bring the vaccine to patients, we needed to show it was safe and effective in preventing illness, severe disease, and hospitalizations. The primary goal was to protect the vaccinated individual. I appreciate that, but my question remains unanswered. On December 3, 2020, your CEO stated that it was uncertain if vaccinated individuals could carry and spread the virus. Was he correct that Pfizer did not know if the vaccine could reduce transmission? We designed our clinical programs with regulatory agencies to demonstrate the vaccine's safety and effectiveness in preventing infections. Okay, let’s move on.

The COVID-19 vaccines have proven to be highly effective in the real world. Both the mRNA vaccine and another vaccine have shown efficacy rates of 94% to 95% for mild to moderate disease. In fact, the real world effectiveness of these vaccines is even more impressive than the results of the clinical trials. It is clear that these vaccines are highly effective in preventing COVID-19.

The omicron variant is a variant of concern, but there's no need to panic. It has many mutations that may allow it to enter our cells more easily, but it's unclear if it's more harmful or just more contagious. In South Africa, cases increased without a rise in deaths or hospitalizations, which is reassuring. Scientists are currently assessing the effectiveness of existing vaccines and treatments, including monoclonal antibodies, against this variant. Vaccine manufacturers like Novavax, Pfizer, and Moderna are proactively testing boosters specifically for omicron. Vaccination remains the best protection, and it's not too late to get vaccinated or receive a booster, along with the flu shot.

Being vaccinated keeps you safe and reduces transmission. Unvaccinated people pose the highest risk of spreading the virus and facing severe illness. Vaccination offers over a 98% chance of avoiding COVID. The third dose provides protection against severe illness and infection. AstraZeneca's vaccine has been approved but faced bans in some countries. Data shows more COVID deaths in vaccinated individuals in the US. The global vaccination trial proves that vaccines are safe and effective.

Vaccination is crucial for protecting oneself and others, allowing society to return to normal. Vaccinated individuals are unlikely to carry or get sick from the virus. Getting vaccinated and receiving booster shots can save lives and prevent the spread of infection. The probability of reducing transmission is believed to be 100%. Taking vaccines not only protects individuals and their families but also breaks the chain of transmission. Vaccinated people do not become infected and cannot spread the virus. However, it was initially unclear if the vaccines would stop transmission, as the data was limited. The speed of scientific progress necessitated quick action.

Safe and effective vaccines have been developed and millions of doses are being delivered. The vaccines have been rigorously studied and proven to be safe and effective. Researchers have confirmed the safety and efficacy of various vaccines, including the Oxford AstraZeneca and Pfizer COVID-19 vaccines. Vaccination has been deemed safe and effective for children, with Pfizer's vaccine being 100% effective for kids aged 5 to 11. The European Medicines Agency has thoroughly assessed the vaccines and concluded they are safe and effective against COVID-19. The vaccines have undergone extensive testing and have been found to be extremely safe and effective. Overall, vaccines are considered safe, effective, and free.

Multiple studies have shown the safety and effectiveness of COVID-19 vaccines. In Israel, a study found that the vaccines were 97% effective against symptomatic infection and 86% effective against asymptomatic infection in healthcare workers. In the United States, vaccines were 90% effective against any infection and 94% effective against hospitalizations from COVID-19 in healthcare workers across multiple states. The Pfizer vaccine has also been found to be effective against common variants in the US, such as B117 and B1351. Similar effectiveness has been observed with the Moderna and Johnson & Johnson vaccines. Even if someone does get infected after vaccination, the infection is likely to have a lower viral load, be shorter in duration, and have a lower risk of transmission to others.

Pfizer reported its vaccine has 95% efficacy, but this refers to relative risk reduction, not overall risk reduction. In the Pfizer trial, the unvaccinated group had a 0.88% risk of contracting COVID-19, while the vaccinated group had a 0.04% risk. The absolute risk reduction offered by the Pfizer vaccine is 0.84%. The 95% figure represents the relative difference between 0.88% and 0.04%. Relative risk reduction can be misleading, and the FDA recommends using absolute risk reduction instead. It is important to consider how many people would have chosen to take the vaccines had they understood the less than 1% benefit. In Canada, any potentially serious risk must be disclosed.

Getting the third vaccine dose offers protection against severe illness and reduces the risk of initial infection. However, even with two, three, or four doses, the vaccine is not very effective at preventing infections altogether. This is evident in the tens of thousands of cases reported during this wave.

Vaccination is crucial for protecting oneself and others, and for society to return to normal. Vaccinated individuals are less likely to transmit the virus or get sick. Getting vaccinated and receiving booster shots can save lives and prevent the spread of infection. The goal is to become a dead end for the virus, stopping its transmission. Vaccinated people do not get infected and cannot be used as hosts to spread the virus. However, the initial emergency use authorization did not have sufficient data on the vaccine's effectiveness against transmission. The speed of scientific progress necessitated quick action.

Vaccinated individuals are protected against COVID-19 and its variants, as the vaccines are highly effective. They do not carry the virus, get sick, or transmit it to others. Vaccination allows society to return to normal by reducing transmission. Getting both vaccine shots is crucial. Vaccinated people are safe from hospitalization, ICU stays, and death, and they no longer need to wear masks. However, they cannot prevent transmission. Israel's experience suggests a waning of immunity, indicating the need for booster shots. The plan is for every adult to receive a booster shot. Overall, vaccines have been a highly successful investment.

The speaker acknowledges that the vaccine did not completely stop the spread or infection, but clarifies that initially it did for the Wuhan strain and the alpha strain. Early data and literature published in the New England Journal showed that those who were vaccinated and didn't get infected were not transmitting the virus to others. The vaccine had a high efficacy of up to 96% early on and this efficacy did not change over time.

The speaker acknowledges that the vaccine did not completely stop the spread or infection, but clarifies that initially it did for the Wuhan strain and the alpha strain. Early data and literature published in the New England Journal showed that those who were vaccinated and didn't get infected were not transmitting the virus to others. The vaccine had a high efficacy of up to 96% early on and this efficacy did not change over time.

Pfizer's claim of 96% efficacy for their vaccine was questioned. The study and data were not independently verified, and Pfizer wanted to keep the data hidden for 75 years. The true effectiveness of the vaccine, based on absolute risk reduction, is less than 1%. More people died and were harmed in their trials compared to the placebo group. The vaccine's safety was questionable from the start, and it is not effective. Additionally, appropriate studies were not conducted for new variants.

I spent 9 months researching the Pfizer vaccine with whistleblowers and scientists. Trials showed a 1 in 800 risk of serious harm from the vaccine, higher than COVID hospitalization rates. Other vaccines were pulled for less harm. Serious harm included hospitalization, disability, and life-changing events, with 40% related to clotting disorders.

Vaccinated individuals are protected against COVID-19 and its variants, as the vaccines are highly effective. They do not carry the virus, get sick, or transmit it to others. Vaccination allows society to return to normal. Fully vaccinated people no longer need to wear masks or practice physical distancing, and they are unlikely to be hospitalized or die from the virus. However, vaccines only slightly reduce transmission, and there is a need for new vaccination strategies. Reports from Israel suggest a waning of immunity, indicating the importance of booster shots. The plan is for every adult to receive a booster shot.

Vaccination not only protects individuals but also reduces virus transmission, helping society return to normal. Current data indicates that vaccinated individuals do not carry the virus or get sick. Getting vaccinated and boosted can save lives and prevent serious illness. The goal is to stop the virus from spreading by ensuring vaccinated individuals act as dead ends for transmission. Vaccines are effective enough that when a vaccinated person is exposed, the virus cannot infect them or spread further. However, there was uncertainty about the vaccines' ability to stop transmission at the time of emergency use authorization. The data on this was limited, and it was acknowledged that the speed of development impacted the understanding of transmission prevention.

Vaccinations provide strong protection against COVID-19, preventing infection, hospitalization, and death. They are effective against variants and help society return to normal. Fully vaccinated individuals no longer need to wear masks or practice physical distancing. However, vaccines do not completely stop transmission, and there is a risk of waning immunity over time. Israel's experience suggests the need for booster shots to maintain protection. The goal is to ensure every adult receives a booster shot. Overall, vaccines are a valuable investment.