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What was once considered an "old timer's disease" actually begins in your 20s and 30s, though diagnosis often occurs much later. Epidemiological data indicates that Alzheimer's diagnoses are increasing in the 40-50 age range, not just in the 60-70 range. Just as prediabetes and insulin resistance can be identified early, it's now possible to see what's happening in the brain much earlier. This allows for intervention and prevention of progression to full-blown dementia.

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Sugar consumption has increased 400-fold since 1964, and blood sugar is the root of much illness. Alzheimer's disease is type three diabetes, or insulin resistance in the brain. The brain is crack-addicted to sugar and even secretes its own insulin. The brain will take what it needs, leaching calcium from bones or stripping amino acids from muscle. If the brain wants sugar, it activates the r f one a two receptor on the back of the tongue, which provides a dopamine release when sugar is consumed. The trick is you have to swallow.

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They told you that Alzheimer's is a mystery, there’s no cure, and it’s just bad luck and age. But the message shifts: the truth about Alzheimer's is darker than you think, and a history they buried is revealed. Alzheimer's was almost non-existent before the twentieth century: no epidemics, no memory-loss nursing homes. Why is it now the sixth leading cause of death in the US? The trail starts with who discovered Alzheimer's. A man named Alloy Alzheimer in 1906, but he didn’t name the disease; Emile Crablin did, a man working with big pharma to classify mental disorders. Pharma began searching for treatments the exact same year the disease was named. In the nineteen nineties, they told you that Alzheimer's was from plaques and tangles in the brain, and big pharma made drugs to target the plaques. Billions were spent, decades wasted, and not a single drug worked because the plaques weren’t the issue. Then in 2022, scientists dropped a bomb: the original Alzheimer's research was faked, a key study that launched decades of pharma drugs fabricated images. An entire field of medicine built on lies. And here’s what they don’t want you to know: Alzheimer's isn’t a brain disease. It is a metabolic disease. Some call it type three diabetes, because Alzheimer's brains can’t use glucose. Modern agriculture played a big part. So what’s causing it? Sugar overload, processed and fake foods, a sedentary life, inflammation, statins (the cholesterol drugs), chemicals, and toxins. Cholesterol is involved because your brain is made of fat and cholesterol. Didn’t know that? And statins lower cholesterol, which means your brain gets starved. Low cholesterol leads to memory loss, confusion, and brain fog—the same symptoms they call Alzheimer's. People who fast regularly have low Alzheimer's risk. People who move daily have low Alzheimer's risk. People who eat nutrient-dense natural foods have low Alzheimer's risk. But that isn’t mentioned. Why? Because fasting and walking cannot be patented. The Alzheimer’s industry is worth 300,000,000,000. Drugs that don’t work, nursery homes that sedate, doctors who never ask about diet, lifestyle, or insulin. It’s not about curing you; it’s about billing you for life. The cure for Alzheimer's is not in a lab or a pill. It’s what you eat, how you move, how you detox, how you stay away from drugs and pills, how you stay away from fear-mongering and stress, and how you protect your brain from big pharma lies. Alzheimer’s didn’t just happen; they created it. They named it, they patented it, and they profited from it. Now they want you to forget how it started. You’ve let someone’s name define your health, but not anymore. Wake up. You are in control. It is not genetic. Comment Alzheimer’s below and I’ll make part two.

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Type three diabetes is also known as diabetes of the brain. Insulin is important for brain function, and when the brain stops using insulin or becomes insulin resistant, cognitive and brain function declines. In the early 2000s, Alzheimer's was considered type three diabetes. Signs of type three diabetes include confusion and memory loss. As the health issue progresses, simple daily tasks become difficult, such as getting dressed or using the washroom. Some people have difficulty speaking and eventually stop recognizing family and friends. Symptoms that lead up to Alzheimer's, like insulin resistance, are preventable with lifestyle and diet changes. Insulin resistance can be reversed, reducing the risk of Alzheimer's disease.

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Alzheimer's and dementia are actually type 3 diabetes, caused by insulin resistance in the brain. Elevated blood sugar levels for 10 years prior to diagnosis are common in early onset patients. The misconception that these diseases cause memory loss is incorrect; patients lose access to their memories, but this access can be restored. The brain consumes 45% of the carbohydrates we consume, and it will take what it needs from other sources, such as calcium from bones or amino acids from muscle tissue. The brain also activates a receptor that rewards us with dopamine for consuming sugar, leading to addiction for many.

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Alzheimer's and dementia should be called type three diabetes, as they are caused by insulin resistance in the brain. The brain makes its own insulin, despite what endocrinologists say about the pancreas being the sole producer. The brain becomes addicted to sugar and will do what it takes to get it, including stripping calcium from bones or activating the r f one a two receptor for a dopamine reward. Excess sugar in the brain is stored as amyloid plaque in the neurosynaptic junctions. People with Alzheimer's are not losing their memory, but rather losing access to it due to this buildup.

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The central feature of almost all age related disease, heart disease, cancer, diabetes, dementia is something called insulin resistance. We eat an average of about 152 pounds of sugar per person and 133 pounds of flour per person every year. This makes up about 60% of our calories and it's killing us and it's making us age very, very fast. And it is something we can completely reverse. I remember one of the top cardiologists at Harvard saying that if you found a group of 100 year olds with clean arteries, they would have one thing in common. They would be insulin sensitive. They could perfectly regulate their blood sugar with very little insulin. And this, my friends, is the key secret of healthy aging.

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We are one of the few nations still calling Alzheimer's and dementia Type 3 diabetes. Insulin resistance in the brain, known as Type 3 diabetes, is the main cause of Alzheimer's. The myth that Alzheimer's is memory loss is false; it's actually loss of memory access, which can be restored. Look into the link between COMT gene mutation and diabetes. Insulin's main role is not to lower blood sugar, but to block other energy use in the body.

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Forty-five million living Americans are expected to die of Alzheimer's if prevention and treatment don't improve. It is the number two cause of death in the UK and affects women more than men in the US. Alzheimer's is among the top killers and the most expensive, costing the average American $350,000, often in nursing home care. It's argued that with current knowledge, Alzheimer's should be optional, and future generations don't have to worry about it. For older generations, it surpassed cancer as the biggest concern about fifteen years ago. Mainstream medicine is currently backward in its approach, and spreading awareness is crucial because much can be done.

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To overcome Alzheimer's, it is crucial to avoid a specific food that worsens symptoms. Insulin plays a protective role in the brain, preventing the development of amyloid plaques and tangled fibers. However, consuming carbs increases insulin, leading to insulin resistance. This resistance creates a deficiency of insulin inside cells, including the brain. Carbs, especially sugars and refined grains, also cause inflammation and mitochondrial damage in the brain. To address insulin resistance, it is recommended to follow a ketogenic diet, lower carb intake, and practice intermittent fasting, such as one meal a day. Additionally, reducing stress is important as it can increase cortisol levels and glucose, contributing to insulin resistance. A nutrient-dense and healthy meal is essential.

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Dementia, including Alzheimer's, can be reversed with the right protocol. The spike in Alzheimer's cases in the 1990s is linked to the fear of high cholesterol and fat due to statin drugs. Lack of proper brain nourishment leads to brain shrinkage and plaque development over time. By implementing the correct protocol, we can rebuild the brain and rescue individuals from this condition.

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The brain is the most metabolically demanding organ, relying heavily on blood flow for cognitive function. Improved blood flow enhances cognition, while restricted blood flow impairs it. Age-related cognitive decline and dementia are sometimes called type three diabetes or diabetes of the brain. Some Alzheimer's patients find relief on ketogenic diets, which isn't a cure, but can improve brain function by improving blood flow and reducing inflammation. Inflammation depletes cognitive function, while reducing inflammation enhances it.

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A healthy rat can navigate through water to safety, while another rat, fed a diet similar to a typical North American one, struggles to find its way. The latter rat's brain has been damaged, leading to memory loss and decreased cognitive abilities, similar to Alzheimer's disease in humans. Researchers believe that Alzheimer's may actually be a form of brain diabetes, linked to insulin levels affected by excessive sugar consumption. Insulin resistance can occur in various organs, including the brain, leading to cognitive decline.

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Alzheimer's is a vascular disease characterized by reduced blood flow to the brain (focal ischemia) and insulin resistance, sometimes called diabetes type three, which impairs glucose uptake by brain cells. This leads to oxidative stress, immune dysfunction, and misfolded proteins, manifesting as tau tangles and amyloid plaques. Nitric oxide can potentially correct all known aspects of Alzheimer's. It improves blood flow and glucose uptake in the brain, addresses the metabolic component, reduces inflammation, inhibits oxidative stress, and prevents immune dysfunction.

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Speaker 0 discussed dietary patterns and Alzheimer's risk. A fat-based diet, including fish, healthy oils, avocados, nuts, and seeds, was associated with a 42% lower risk of developing Alzheimer's disease. A protein-based diet, described as resembling a caveman diet, was linked to a 21% lower risk. In contrast, a standard American diet high in simple carbohydrates—bread, pasta, potatoes, rice, fruit juice, and sugar—was associated with a 400% increased risk of Alzheimer's disease. The rise in risk is attributed to sugar and foods that quickly convert to sugar, aligning with the insulin diabetes type 3 hypothesis. The importance of management is emphasized. The explanation connects high blood sugar to brittle blood vessels, making them more likely to break, which slows healing and increases the likelihood of stroke. It is stated that having a stroke increases the risk of Alzheimer's tenfold.

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What was once considered an "old timer's disease" actually begins in your 20s and 30s, though diagnosis often occurs much later. Epidemiological data indicates that Alzheimer's diagnoses are increasing in the 40-50 age range, not the 60-70 range. Just as prediabetes and insulin resistance can be identified early, it's now possible to detect early signs of Alzheimer's. This allows for intervention and prevention of progression to full-blown dementia.

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Alzheimer's is referred to as type three diabetes, meaning insulin resistance in the brain. Our brains become highly dependent on sugar, and the brain manufactures its own insulin. The problem is that when insulin resistance occurs in the brain, unlike the body, there isn’t a stored-sugar exchange through glycogen. The body stores sugar as glycogen in the liver and muscles and can release glucose back into the bloodstream, but the brain lacks this same storage-and-release mechanism. Within the brain, there are neurosynaptic junctions—little spaces where nerve endings don’t touch, and signals jump across the gap. When these gaps fill with amyloid plaques and neurofibrillary tangles, people say that’s the genesis of Alzheimer's. However, the transcript states that the truth is the genesis of it was insulin resistance.

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Ten percent of 65-year-olds, 25% of 75-year-olds, and 50% of 85-year-olds will develop dementia or Alzheimer's disease. Despite spending over $2 billion on drug treatments, there has been no success. Scientists at Brown discovered insulin resistance in the brain, likening Alzheimer's to type 3 diabetes. Poor metabolic health, often due to insulin resistance caused by excessive insulin and sugar, is a significant factor in Alzheimer's. Evidence of Alzheimer's can appear 30 to 40 years before symptoms arise. The prevalence of sugar and starch in diets contributes to diabetes of the brain. Understanding this connection can lead to brain healing.

Mind Pump Show

What You Learned About the BRAIN Is WRONG! This Is What NEW STUDIES Are Showing | Max Lugavere 1875

Guests: Max Lugavere, Paul Grewal, Layne Norton

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Alzheimer's is a growing health crisis, with cases expected to triple by 2030. Currently, individuals reaching age 85 face a 50% chance of diagnosis. Recent revelations have shown that a pivotal 2006 paper supporting the amyloid hypothesis—linking amyloid beta plaques to Alzheimer's—was based on fraudulent data, undermining nearly a century of research focused on pharmaceutical cures. While amyloid plaques are present in many older adults without cognitive deficits, alternative theories, such as the metabolic origin theory, suggest Alzheimer's may stem from glucose hypometabolism in the brain. Despite the amyloid hypothesis directing funding and research, drug trials have largely failed, with a 99.6% failure rate. Controversial drugs like aducanumab, which reduce plaque but do not improve cognition, have raised ethical concerns. The discussion also highlights the overlap between Alzheimer's and other neurodegenerative diseases, emphasizing the importance of neuroinflammation and oxidative stress. The conversation shifts to the role of lifestyle factors in preventing Alzheimer's, with modifiable risk factors including diet, exercise, and social connections. Acknowledgment of the potential for prevention has grown, with studies indicating that up to 40% of dementia cases may be preventable. The hosts stress the need for a holistic approach to brain health, advocating for dietary and lifestyle changes to mitigate risks associated with Alzheimer's and other cognitive decline.

Genius Life

FIX THIS To Hack Your Age & LIVE LONGER Today! | Max Lugavere & Ed Mylett

Guests: Ed Mylett

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Chronic hyperinsulinemia can lead to hypertension, a modifiable risk factor for dementia. Elevated insulin levels cause the kidneys to retain sodium, raising blood pressure. A low-carb diet can significantly reduce insulin secretion. Insulin is essential for glucose metabolism, but chronic elevation prevents fat utilization, which is crucial for brain energy. Vascular health is vital for cognitive function, as vascular dementia is common. Consuming carbohydrates in concentrated meals rather than spreading them throughout the day may reduce insulin secretion, especially for those with insulin resistance. Regular health screenings, including fasting blood glucose and insulin tests, are recommended to monitor metabolic health. The HOMA-IR calculation can assess insulin sensitivity, which is linked to brain energy production. Genetic factors, such as the APOE4 allele, can affect glucose metabolism and increase dementia risk. Amyloid plaques and tau tangles are associated with Alzheimer's disease, but their presence alone does not determine causation. Neuroinflammation and sleep are critical for brain health, as sleep helps clear amyloid from the brain. Diet plays a significant role; ultra-processed foods contribute to obesity and nutrient deficiencies. Avoid refined grains and seed oils, which spike blood sugar levels. Incorporating healthy fats with vegetables enhances nutrient absorption. Regular sauna use and stress management techniques can improve overall health and resilience.

The Dhru Purohit Show

Worst Thing In The World Feeding Alzheimer's & Dementia! - Fix This ASAP In 2025 | Ben Bikman

Guests: Ben Bikman

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Alzheimer's disease has traditionally been viewed as a result of amyloid beta plaques and neurofibrillary tangles in the brain, which can only be confirmed postmortem. This has led to a need for a paradigm shift in understanding the disease. Emerging research suggests a metabolic theory of cognitive decline, indicating that markers of metabolic health, such as fasting insulin and glucose levels, may be more predictive of Alzheimer's risk than age. A Finnish study found that fasting insulin was a stronger predictor of Alzheimer's than age. The hippocampus, crucial for memory and learning, relies on glucose and ketones for energy. Insulin regulates glucose transport in the hippocampus, and as insulin resistance develops, the brain struggles to access glucose, leading to an energy deficit. This has led some researchers to label Alzheimer's as "type 3 diabetes," highlighting the connection between insulin resistance and cognitive decline. Insulin's role extends beyond glucose control; it affects every cell in the body. Chronic high carbohydrate intake leads to elevated insulin levels, causing insulin resistance and metabolic dysfunction. This dysfunction can manifest in various health issues, including cognitive decline, PCOS, and erectile dysfunction, all linked to insulin resistance. Research indicates that even in early cognitive decline, glucose metabolism in the brain is impaired while ketone metabolism remains intact. Studies show that dietary changes, particularly reducing carbohydrates and increasing healthy fats, can improve cognitive function. The food we consume plays a critical role in either exacerbating or alleviating chronic diseases, including Alzheimer's. To combat cognitive decline, individuals should focus on improving metabolic health through dietary changes, such as reducing refined carbohydrates and increasing healthy fats. This approach not only addresses Alzheimer's risk but also enhances overall well-being. The message is one of empowerment: individuals can take control of their health through informed dietary choices.

The Dhru Purohit Show

The ROOT CAUSE Of Alzheimer's & How To REVERSE IT! | Dr. Dale Bredesen

Guests: Dale Bredesen

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Alzheimer's disease typically takes about 20 years from the onset of pathophysiology to diagnosis. Cognitive improvement is possible at any age by addressing underlying causes, such as unrecognized toxins or pathogens. Notably, nocturnal oxygen desaturation is critical; studies show that low oxygen levels during sleep correlate with brain volume loss. Many people are unaware of their declining oxygen saturation due to conditions like sleep apnea, which can starve the brain. As the aging population grows, cognitive decline has become a primary concern, surpassing cancer. Currently, around 5.6 million Americans have an Alzheimer's diagnosis, but projections suggest that 45 million could eventually die from the disease. Factors like obesity, poor immunity, and low vitamin D levels increase risks for both Alzheimer's and COVID-19. The complexity of Alzheimer's means it cannot be attributed to a single cause. Early lifestyle factors in younger individuals can increase future risk. The disease is often linked to inflammation, toxins, and hormonal deficiencies. For instance, insulin resistance contributes to cognitive decline through inflammation and reduced trophic support. Addressing these factors early can prevent or reverse symptoms. Dale Bredesen emphasizes the importance of personalized approaches to treatment, identifying root causes, and creating targeted interventions. His research indicates that multiple contributors, including toxins from mold and environmental factors, must be addressed for effective treatment. The Bredesen protocol encourages individuals over 45 to undergo a "cognoscopy" to assess cognitive health proactively. Success stories illustrate that individuals can improve their cognitive function by following a comprehensive protocol that includes lifestyle changes, dietary adjustments, and addressing environmental toxins. The narrative of patients like Deborah, who recognized early signs of cognitive decline and sought intervention, highlights the importance of early detection and personalized care. The overarching message is that Alzheimer's can be an optional disease with appropriate preventive measures and lifestyle adjustments.

The Dhru Purohit Show

DOCTORS REVEAL How to PREVENT Alzheimer's in 6 SIMPLE STEPS!

Guests: Ronesh Sinha, Lisa Mosconi, Dale Bredesen

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Alzheimer's disease is projected to affect 45 million Americans, with lifestyle factors like diet and insulin resistance playing critical roles in brain health. The Western diet accelerates brain aging, while fasting can help reverse these conditions. Insulin resistance occurs when the body struggles to manage glucose, leading to various metabolic issues. This condition can manifest years before glucose levels rise, making it essential to monitor waist circumference and lipid panels as early indicators. The link between insulin resistance and Alzheimer's is significant; elevated glucose and insulin levels can hinder the brain's ability to clear amyloid plaques, which are associated with Alzheimer's. Chronic inflammation and insulin resistance create a perfect storm for neurodegenerative diseases. To reduce Alzheimer's risk, individuals should evaluate their lifestyle and health metrics, focusing on triglyceride levels, HDL cholesterol, liver function tests, and inflammation markers. Dietary habits, particularly carbohydrate intake, are crucial in managing insulin resistance. Many people, especially those from South Asian backgrounds, may consume healthy foods that still contribute to insulin resistance due to high carbohydrate content. The concept of "skinny fat" highlights that individuals can appear thin yet have high visceral fat, which is more harmful than subcutaneous fat. This phenomenon is particularly prevalent in certain ethnic groups, where even small amounts of excess weight can lead to significant metabolic issues. The discussion emphasizes the importance of personalized nutrition and exercise, as well as the need for awareness about the impact of modern diets and sedentary lifestyles on health. Fasting and meal sequencing can help manage blood sugar levels, and incorporating more vegetables and healthy fats into meals can mitigate the effects of carbohydrates. Women are disproportionately affected by Alzheimer's, with hormonal changes during menopause contributing to cognitive decline. Estradiol, a key hormone, supports brain health, and its decline can lead to increased risk for Alzheimer's. Understanding these changes is vital for prevention, and early intervention can significantly impact long-term health outcomes. The conversation also touches on the importance of addressing environmental toxins, such as heavy metals and mold, which can contribute to cognitive decline. Regular monitoring and proactive health measures, including brain scans and lifestyle modifications, are essential for reducing the risk of Alzheimer's and other neurodegenerative diseases. Overall, the key takeaways include the importance of diet, exercise, hormonal health, and environmental factors in maintaining cognitive function and preventing Alzheimer's disease. Individuals are encouraged to take proactive steps in their health journey, focusing on personalized strategies that align with their unique needs and backgrounds.

The Dhru Purohit Show

Silent Symptoms Of Dementia & Brain Decline: Spot These Early Warning Signs | Dr. David Perlmutter

Guests: David Perlmutter

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David Perlmutter discusses the long-term development of Alzheimer's and dementia, emphasizing that symptoms often manifest decades after initial metabolic issues arise. Key early warning signs include waist circumference, blood sugar, blood pressure, and physical activity levels. Addressing these factors can potentially reduce Alzheimer's risk by up to 70%. Brain metabolism, particularly glucose utilization, is critical, and deficiencies can be detected years before cognitive decline. Perlmutter highlights the importance of lifestyle choices in preventing neurodegenerative diseases, noting that obesity, pre-diabetes, and hypertension compromise brain health. He critiques the reliance on pharmaceuticals, stating that current Alzheimer's treatments have not significantly improved cognitive function and can even cause harm. Instead, he advocates for preventive measures and lifestyle changes. He stresses the significance of maintaining a healthy lifestyle, including regular exercise, proper nutrition, and mental stimulation, to mitigate risks associated with the APOE4 gene, which is linked to Alzheimer's. Perlmutter also discusses the role of sleep in brain health, emphasizing its importance for cognitive function and metabolic regulation. The conversation touches on the impact of environmental toxins on brain health and the necessity of a balanced diet rich in nutrients, including DHA from fish, which supports brain cell function and reduces inflammation. He advocates for personalized supplementation based on individual health needs, including glutathione and multivitamins. Perlmutter concludes by promoting a proactive approach to brain health, encouraging individuals to take control of their lifestyle choices and seek out resources for prevention and education, such as the upcoming Alzheimer's Prevention Day.

The Dhru Purohit Show

How Insulin Resistance DESTROYS Your Brain & Causes ALZHEIMER'S / DEMENTIA! | Ben Bikman

Guests: Benjamin Bikman

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In this podcast episode, Dr. Benjamin Bikman discusses strategies to improve insulin sensitivity and reduce the risk of Alzheimer's disease and cognitive decline. He emphasizes the need to shift the current paradigm in understanding Alzheimer's, which has traditionally focused on amyloid plaques and neurofibrillary tangles, to a metabolic perspective. Research indicates that fasting insulin levels are more predictive of Alzheimer's risk than age, suggesting that metabolic health is crucial in understanding cognitive decline. Dr. Bikman explains that the hippocampus, essential for memory and learning, relies on glucose and ketones for energy. Insulin resistance in the hippocampus can lead to an energy deficit, contributing to cognitive decline. He introduces the concept of "type 3 diabetes," referring to insulin resistance in the brain, which parallels type 2 diabetes. This highlights the metabolic origins of Alzheimer's, suggesting that poor metabolic health is a significant factor. The discussion also covers the impact of diet on insulin sensitivity. Dr. Bikman advocates for reducing processed carbohydrates and increasing healthy fats, particularly from animal sources and fruits like avocados and olives. He warns against industrial seed oils, which contribute to inflammation and insulin resistance. The conversation touches on the importance of maintaining a balanced omega-6 to omega-3 ratio to mitigate inflammation, which is linked to cognitive decline. Dr. Bikman encourages listeners to recognize early signs of cognitive impairment and take proactive steps to improve metabolic health through dietary changes, stress management, and inflammation control. He asserts that food can be a powerful tool in preventing and potentially reversing cognitive decline, empowering individuals to take charge of their health.