TruthArchive.ai - Tweets Saved By @Outdoctrination

Posted - July 25, 2024 at 10:02 PM

Saved - October 16, 2025 at 4:06 AM

reSee.it AI Summary

I explore a guy’s claim that quitting sugar improves health, noting it’s biased and often misleading. I pull apart his flaws: cravings aren’t inherently bad signals; health issues aren’t solely due to sugar; don’t ignore real problems. I argue donuts aren’t just sugar, focus on flour, fortification, gums, dyes, and additives harming gut. Replacements and lifestyle changes matter; sugar isn’t the sole villain. If you want help, I offer guidance.

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Quitting sugar really improved this guy's health. Good video. Only one problem: it's full of lies. Sugar gets a bad rep because of countless reports like this. Let's unveil the truth behind it⬇️

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Not trying to pick on this guy - but it's a good example as it is very representative of many people's experience "quitting sugar," and why so many people think it is bad. Without addressing any of the health claims made in the video, let's just talk about his experience.

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Problem #1: Claiming your cravings are inherently bad and not a signal you should listen to. Problem #2: Noticing something bad about your health and ascribing it to sugar, because we already know that sugar is bad, rather than trying to figure out the real problem.

Video Transcript AI Summary

Last year, I developed a bad habit of snacking and found myself lacking self-control in the face of a free doughnut or plate of cookies. I kept justifying my actions with reasons like, “well, I did go to the gym today” and “overall, I ate pretty healthy,” insisting the occasional slip wasn’t a problem. However, the pattern intensified as I started indulging more frequently, moving from occasional slips to doing it every day. This shift became noticeable not just in my eating pattern but in my body as well. Despite exercising often, I recognized changes in my physique that concerned me, specifically the emergence of an early onset dad gut. The combination of persistent snacking and the way it was affecting my body prompted a decisive decision. I chose to quit sugar for thirty days as a deliberate corrective measure aimed at breaking the cycle of impulsive snacking and addressing the unintended physical changes. The decision to quit sugar was driven by the realization that the current trajectory wasn’t aligning with my health and fitness efforts. Even with regular workouts, the daily indulgences were undermining progress and contributing to unintended weight distribution. The plan to abstain from sugar for a defined period was intended to reset habits, test whether reducing sugar intake could curb cravings, and restore better control over eating decisions. In summary, the key sequence began with a drifting habit of snacking, followed by justifications that masked the growing frequency of indulgences, then a self-aware recognition that the pattern was escalating despite regular exercise. The observable consequence—an early onset dad gut—served as a turning point, leading to a concrete commitment: quit sugar for thirty days. This decision reflects a proactive attempt to realign eating behavior with fitness goals and to address the physical changes appearing alongside the ongoing habit.

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Speaker 0: Last year, had developed a bad habit of snacking. I had lost all self control in the face of a free doughnut or plate of cookies and I made justifications for my actions. Excuses like, well, I did go to the gym today. Overall, I ate pretty healthy. It's not like I do this every day until I started to do it every day. I knew something had to change when even though I exercise often, I noticed I was developing early onset dad gut. So I decided to quit sugar for thirty days.

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I've written before about how not having a sweet tooth is actually a common sign in aging, stress and depression, while a strong sugar craving is associated with youth and health.

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Why sugar cravings are a good thing. One of the most reliable and well studied ways to recognize chronic stress, depression and anhedonia is to measure SUCROSE (table sugar) PREFERENCE. It is well known that craving sugar is a sign of high pleasure sensitivity and youth, and declines in aging. If you've completely lost your sweet tooth - probably not a good sign. A sign of low dopamine, high serotonin. Aging. Of course, a ravenous + insatiable appetite for anything, including sugar, is also a sign of dysfunction, but losing appetite and sweet craving is a good way to know you're under some serious, chronic stress. In other words, if sugar can't get you excited - nothing else will.

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Reduce sugar cravings? Not a good idea! Sugar cravings are actually an excellent sign of youth and health. If you no longer crave sugar, it's a sign you've lost the ability to feel pleasure from life generally, as sugar is one of our primary pleasure signals. This loss of

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His definition of sugar (as many others) is donuts and cookies. A quick look at a typical donut nutrition tells us: 1. The majority of the calories are from fat, not sugar 2. The majority of carbs are non sugar The same is true for cookies, cakes, etc

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Then we get into the crux of the matter, the ingredients of "sugar." Flour: gluten, pesticides which can certainly cause issues. Fortified with iron, another huge problem. Gums. Tons of emulsifiers. Colorings. The list goes on. A bit of a confounder, don't ya think?

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I've talked about the issues with iron fortified foods, specifically in the gut here

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A hidden cause of your digestive pain, bloating, and gas. Adding this to our food has caused an epidemic of digestive issues. And no one is talking about it… Let’s dive in.

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And just scratching the surface on food additives here.

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THIS might just be causing your gut problems. The FDA has swept these under the rug for decades. We’re now waking up to the harms of these so-called “safe” ingredients, added to nearly every commercial food. Let’s talk about it⬇️

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The toxicity of food dyes

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ADHD induced by food dyes. Tartrazine (aka FD&C Yellow 5, Yellow 5 Lake) + Carmoisine (FD&C Red No. 10) can cause hyperactive symptoms in children. These dyes are EVERYWHERE, and are said to be harmless, but have neurological and gut disrupting properties. Watch out.

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It’s also recently been shown that the ubiquitous food dye, red 40 or Allura Red AC, can cause inflammatory bowel disease outright, you guessed it, by increasing gut serotonin. This was mediated by inducing dysbiosis and subsequent inflammation in the gut, along with increasing

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Gums and emulsifiers are destroying our guts

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Hidden ingredients in food RUINING our digestion + metabolism. Common commercial food additives: • Mono and diglycerides • Lecithin • Carboxymethylcellulose once again being shown to induce: • Insulin resistance • Gut dysbiosis • Intestinal inflammation Check. Your. Labels.

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Polysorbate 80 and carboxymethylcellulose are absolutely ubiquitous in foods and supplements. In rodent studies, these emulsifiers cause dysbiotic bacterial overgrowth and support the genesis of COLITIS, i.e inflammatory bowel disease.

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But because sugar has been the target for so long, people just gloss over all of this and blame the one ingredient that is barely in the food at all. He even says he starts reading labels, yet only comments on the amount of sugar and not the amount of emulsifiers, dyes, etc

Video Transcript AI Summary

- The speaker knew they were consuming a decent amount of sugar, but without reading labels and examining weekly snacks and meals, they wouldn’t know for sure. - No-brainers identified: ice cream is loaded, chocolate snacks are packed, and a once-a-month energy drink. - They were surprised to find a lot of sugar in protein bars. - Breakfast cereal is basically a dessert. - Even bread had five grams of sugar per slice. - For those with little self-control, the only way to regain control is to completely change the environment; it’s impossible to eat snacks you refuse to purchase and bring into your home in the first place, so all of this stuff needs to go. - The cravings were the worst during the first couple days.

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Speaker 0: I knew I was consuming a decent amount of sugar, but without reading the labels and digging into weekly snacks and meals, I wouldn't know for sure. There were, of course, some no brainers. Ice cream is loaded, chocolate snacks are packed, my once a month energy drink. But I was also surprised to find a lot of sugar in my protein bars. My breakfast cereal is basically a dessert. Even the bread I was buying had five grams a slice. If you're like me and you have very little self control, the only thing you can do to regain control is to completely change your environment. It's impossible to eat snacks that you refuse to purchase and bring into your home in the first place. So all this stuff needs to go. The cravings were the worst for the first couple days.

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Then, what does he replace it with? First meal: chicken, bacon, rice. Not the ideal meal, but certainly WAY easier on the gut than the concoctions that he ditched: protein bars, cookies, energy drinks, etc He's also starting to think about what he's eating, which is good!

Video Transcript AI Summary

Acknowledging that tonight's dinner is best described as a bowl of food, the speaker shows the meal consisting of rice, chicken, and bacon described as the daily recommended amount, and notes that they should be eating more vegetables.

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Speaker 0: Alright. So tonight's dinner can really only be described as a bowl of food. Here, let me show you guys what we're working with here. We've got your rice, your chicken, and your daily recommended bacon. I should be eating more veg.

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Next: Fish, brown rice, chicken broth, cooked veggies. Not only are all of these foods low in gut irritants, but they actually provide nutrients most people lack. Fish has iodine, selenium, taurine. Broth has glycine, proline. but no sugar, which is what gets acknowledged

Video Transcript AI Summary

The speaker discusses dinner options and meals, highlighting a preference for simple, nutritious combinations. They mention that for dinner they would choose fish served with brown rice and sautéed kale, indicating a balanced plate with protein, complex carbohydrates, and vegetables. The conversation then notes that salads have become the speaker’s go-to meal, attributed to their convenience and ease of preparation, suggesting a preference for quick, hassle-free meals that still support a healthy eating pattern. Within the same meal pattern, curry cod with brown rice and sautéed kale is referenced as another dinner option, reinforcing the recurring trio of protein, whole grains, and greens. This inclusion of curry cod expands on the fish-based choices, illustrating variety within a consistent framework of brown rice and sautéed kale. The kale itself is described as being sautéed with chicken broth, a detail that adds flavor while providing a cooking method that the speaker employs to prepare the greens. Additionally, the speaker notes that they are going to drink the chicken broth used to sauté the kale, linking a preparation technique to a beverage choice and implying a preference for consuming the broth alongside or after the meal. The overall pattern emphasizes meals that are straightforward to prepare, with a consistent emphasis on brown rice and sautéed kale as foundational elements across different dishes. The statements collectively convey a practical approach to dinner planning, emphasizing convenience, ease of preparation, and a recurring combination of fish (or cod) with brown rice and sautéed kale. The specific mention of sautéing kale in chicken broth and planning to drink the broth further highlights the speaker’s method of flavoring greens and incorporating the broth into their dining or hydration routine. The closing remark, “This is like a bash,” adds a personal, informal aside that reflects the speaker’s casual tone and perhaps a sense of enjoyment or playfulness about the meal preparation.

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Speaker 0: For dinner, I'd have fish with brown rice and sauteed kale. Salads became my go to meal because they were convenient and easy to prepare. We have curry cod with some brown rice and sauteed kale. In the kale, I actually sauteed it with some chicken broth, which which I'm also gonna be drinking here. This is like a bash

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Now potatoes + veg: lots of potassium, B vitamins, magnesium. All well cooked and should be pretty easy to digest for someone who's already pretty healthy. This also certainly results in eating less calories - which obviously can reduce weight and make someone feel better.

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Now here's the kicker: what else he's done during this experiment. - Started exercising again - Stopped traveling and presumably eating out more but again ascribes the benefit to cutting out sugar.

Video Transcript AI Summary

The speaker reports that the thirty-day challenge is complete and that they feel pretty good. Over the past month, they made a few changes: they started going to the gym more and, as they’re traveling less, have had more consistent activity. They also reduced their carbohydrate intake, partly due to a reduction in added sugar. Regarding the benefit from removing sugar, they admit it’s hard to pinpoint an exact percentage, but, citing Dan Harris, they say, “maybe I was 10% healthier.” They also note that it “definitely made a huge differ.”

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Speaker 0: Alright. So the thirty day challenge is done and I feel pretty good. I feel pretty good. There were a few things that I changed over the past thirty days. I did start going to the gym more and now that I'm not traveling as much. I also reduced my carbs partly because of the reduction in added sugar. And it's hard to pinpoint the exact percentage benefit that I received from getting rid of sugar. To to steal a phrase from Dan Harris, I'd say maybe I was 10% healthier. It definitely made a huge differ

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Then finally, says he still needs to "cheat," and predictably feels awful after eating a donut, or in his words "sugar." Notably, his gut hurts, which drives the point home that commercial foods are horrible primarily due to the way they mess with your digestion/gut bacteria.

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Speaker feels sick and has a stomach ache after eating a donut and a half, saying this is terrible. They decide to give the donuts away. Someone takes the donuts and says, “Thanks for taking these donuts.” The exchange ends with “Bye. Bye. Happy birthday. You.”

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Speaker 0: I feel sick. My stomach hurts. I ate like a donut and a half, and I still feel horrible. This is terrible. Look at this. This is bad. I need to give these donuts away to somebody. Yeah. Thanks for taking these donuts. You're welcome. Bye. Bye. Happy birthday. You.

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So what do we learn? Well, people who say they stopped eating sugar and feel better: ⬩Go into it thinking sugar is bad, so when they get better they confirm this bias (or don't get better but say they do bc of cultural conditioning) ⬩Stop eating a lot of food additives that are horrible for the gut ⬩Start being mindful of what they're eating ⬩Start eating more nutrients + protein ⬩Change other lifestyle factors ⬩Think their cravings are bad but don't get rid of them when they cut sugar ⬩Might lose weight from eating less in general, which everyone likes

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Sugar is not to blame in these situations. If you have sugar to your body's desire, alongside other good lifestyle choices, no garbage additives, lots of nutrient dense foods, etc etc it could and should be part of your life.

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If you want to learn how to incorporate sugar in your diet, while being lean, energetic, having great digestion, mood, & deep sleep, hit us up, we can help. You can schedule a free call by clicking where it says “get started with a free call” here http://www.prism.miami

Prism Health The solution is out there. We can help you find it. prism.miami

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Posted - September 23, 2025 at 12:34 PM

Saved - September 24, 2025 at 10:24 AM

reSee.it AI Summary

Recent research highlights the potential of N-Acetylcysteine (NAC) as a beneficial supplement for autism. A 2016 study showed significant improvements in symptoms, particularly irritability, after 12 weeks of treatment. Additional studies confirmed these findings, indicating NAC's effectiveness even at lower doses. The benefits stem from NAC's ability to balance glutamate levels and provide antioxidant support, addressing key issues in autism. I encourage anyone interested in this approach to reach out for personalized guidance.

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Autism can be substantially improved with a cheap over the counter supplement, recent research has shown. (🧵1/9)

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N-Acetylcysteine is a mental health marvel. From anxiety, to ADHD, autism and even suicidal depression, it acts as a master mood stabilizer. Let's talk about the benefits of NAC, the science and how to use it yourself:

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A paper in 2016 investigated the impacts of N-Acetylcysteine on the symptoms of autism. Autistic children age 3-12 took: ◆ 900 mg for 4 weeks ◆ 1800 mg for the next 4 weeks ◆ 2700 mg for the following 4 weeks (2/9)

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These are the metrics they measured. ABC Irritability Score → Irritability/behavioral outbursts measure CGI Severity Score → Clinician-rated autism severity SRS Total → Social responsiveness/social impairment RBS-R Total → Repetitive behaviors and rituals (3/9)

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NAC had huge improvements for autism - cutting the symptoms of irritability in half. A striking and consistent downward trend in this metric over the 12 weeks, compared to placebo which was unchanged. (4/9)

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NAC also improved other metrics of autism. After 12 weeks: ◇ Stereotyping (repetitive, nonfunctional behaviors, trend) ◇ Hyperactivity (trend) ◇ Social responsiveness total (trend) ◇ Autistic mannerisms (5/9)

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A more recent study backed up these findings. 2 doses of NAC at 400-600 mg per day for 8 weeks. (6/9)

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NAC even at these lower doses still showed benefits for autism. After 8 weeks: CARS Total ↓ (lower autism severity) ABC Total score ↓ (overall problem behaviors) ABC Irritability ↓ ABC Stereotypic behavior ↓ ABC Hyperactivity ↓ (7/9)

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A meta analysis in 2021 once again corroborated these findings. Showed trends for benefits in multiple symptoms of autism. (8/9)

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Why is NAC so helpful for autism? It comes down to two main mechanisms: 1. Glutamate balance 2. Antioxidant support Because NAC supplies free cysteine to the brain - it is able to increase glutamate in the presynaptic region, which inhibits the release of glutamate into the synapse. Overall, this decreases neuronal excitation - a key driver of excitotoxicity which can kill neurons and general hyperactivity. Autism is characterized by excess glutamate and glutamate signaling components. NAC also acts as a precursor to glutathione, the body's master antioxidant. This gives it antioxidant and anti-inflammatory properties, two key processes that impair brain function in autism. (9/9)

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Studies https://journals.sagepub.com/doi/epub/10.1177/0004867420952540 https://sci-hub.se/10.1016/j.biopsych.2012.01.014 https://turkjpediatr.org/article/view/93/93

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If you enjoyed this thread, we take the same creative science-based approach to help people every day with an individualized approach. Schedule a free call here and we’ll help you too: https://go.prism.miami/consultation

Schedule a Free Call with Prism Health Book your free consultation to optimize your health, energy, and vitality. prism.miami

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@RikhzR read til the end

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@TheFirstLoser22 not a coincidence

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@RJMigliaccioIII yes, you see the connection

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Posted - September 23, 2025 at 12:29 AM

Saved - September 23, 2025 at 12:54 PM

reSee.it AI Summary

I discussed the controversial link between Tylenol use and rising autism rates. Historically, aspirin was replaced by Tylenol due to safety concerns, but studies suggest Tylenol, especially during pregnancy, may deplete critical substances like glutathione and sulfate, impacting neurodevelopment. Research indicates a significant association between Tylenol exposure and increased risks of autism and ADHD. Mechanistic insights reveal potential negative effects on brain cell growth and neurotransmitter levels, highlighting Tylenol as a possible contributing factor among many in autism's complex landscape.

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TYLENOL & AUTISM - The science big pharma is begging you not to read: (🧵1/11)

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Historically, aspirin was recommended for children if needed. However, in 1980 the CDC announced an association between aspirin and Reye's syndrome. This caused hospitals to switch over to tylenol (acetaminophen or paracetamol). Autism rates began to skyrocket. (2/11)

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Some evidence pointed to tylenol use combined with MMR vaccines to dramatically raise autism incidence. This association held true even after adjusting for various confounders and inflammatory conditions. Such an association was NOT seen with ibuprofen, and I'll explain why shortly. (3/11)

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Some have speculated that Tylenol, along with other new environmental factors, such as glyphosate, have synergistically promoted the rise in autism. The main mechanistic commonalities? They deplete: ➠ Glutathione: our master detoxifying + antioxidant agnet ➠ Sulfate: needed for steroid hormone transport and detoxification (4/11)

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Studies have confirmed that tylenol (acetaminophen) use is associated with depletions in sulfated steroids across the board. Steroids like: ➥ DHEA-S ➥ Pregnenolone sulfate serve as vital transport mechanisms for these hormones throughout the body, and they are highly involved in: ➥ Neurotransmission ➥ Brain cell growth / maturation ➥ Synaptic plasticity ➥ Functional connectivity all of which have alterations seen in autism.. (5/11)

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The main problem with Tylenol lies in its metabolism. Only a fraction of Tylenol gets excreted, the vast majority of it undergoes enzymatic detoxification. This requires: ➥ Sulfate ➥ Glutathione and can form a highly toxic compound called NAPQI - which poisons mitochondria and leads to tons of DNA damage and oxidative stress. This is one of the reasons it damages the liver, but it does this in the brain as well. Glutathione and sulfate are needed for other functions as well, and their levels are often low in autism. (6/11)

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In a consensus statement put together by 91 scientists in Nature, they warned against these exact issues. They pooled together multiple studies on the issue, and found that: ◇ 26/29 showed associations of Tylenol use in pregnancy + neurodevelopmental disorders ◇ 16/19 showed these associations in a dose dependent manner. (7/11)

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One of the most compelling studies on the topic was published in JAMA in 2019. They measured Tylenol and its metabolites in umbilical cord plasma, showing a: ◇ ~3X increase risk in ADHD ◇ 3-4X increase risk in autism in children. Again, they made sure to adjust for confounders, including maternal illness. (8/11)

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When analyzing the gene expression after Tylenol exposure, some trends stand out. Pathways involved in: ☆ Inflammation ☆ Energy production ☆ Cell death were negatively impacted. Animals also consistently showed behavioral and cognitive impairments when mothers are exposed, or in the perinatal phase. (9/11)

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Tylenol might also negatively impact brain cell growth and development. BDNF is the primary protein involved in signaling to neurons to churn out the machinery needed for robust communication and health. Its levels are shown to decrease substantially in certain brain regions when animals are exposed to it. Another hallmark of autism. (10/11)

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There are some other mechanistic links as well, as its speculated that alterations in neurotransmitter levels and in the endocannabinoid system are also involved. What I've outlined here are the primary links. (11/11)

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sources https://sci-hub.se/10.1016/j.clnesp.2017.10.005 review w glyphosate (DHEA-S depletion, GSH depletion) https://pmc.ncbi.nlm.nih.gov/articles/PMC8540524/ mechs + epi review https://pmc.ncbi.nlm.nih.gov/articles/PMC5835573/ sulfated steroids https://pmc.ncbi.nlm.nih.gov/articles/PMC8580820 26/29 show association, 16/19 dose dependent. endocrine disruption, endocannabinoid involvement https://pmc.ncbi.nlm.nih.gov/articles/PMC6822099/ big association (best til 2019) https://journals.sagepub.com/doi/10.1177/1362361307089518 huge association w vax https://pubmed.ncbi.nlm.nih.gov/26390956/ https://pubmed.ncbi.nlm.nih.gov/26233562/ neurotransmitter alterations https://pmc.ncbi.nlm.nih.gov/articles/PMC9940030/#S18 rna seq https://www.sciencedirect.com/science/article/pii/S0091305717307116#f0025 BDNF https://pmc.ncbi.nlm.nih.gov/articles/PMC12429359/ mitochondrial perspective https://pubmed.ncbi.nlm.nih.gov/33836167/ oxstr

Paracetamol (Acetaminophen) and the Developing Brain Paracetamol is commonly used to treat fever and pain in pregnant women, but there are growing concerns that this may cause attention deficit hyperactivity disorder and autism spectrum disorder in the offspring. A growing number of epidemiological ... pmc.ncbi.nlm.nih.gov

Acetaminophen (Paracetamol) Use Modifies the Sulfation of Sex Hormones Acetaminophen (paracetamol) is one of the most common medications used for management of pain in the world. There is lack of consensus about the mechanism of action, and concern about the possibility of adverse effects on reproductive health. We ... pmc.ncbi.nlm.nih.gov

Paracetamol use during pregnancy — a call for precautionary action Paracetamol (N-acetyl-p-aminophenol (APAP), otherwise known as acetaminophen) is the active ingredient in more than 600 medications used to relieve mild to moderate pain and reduce fever. APAP is widely used by pregnant women as governmental ... pmc.ncbi.nlm.nih.gov

Association of Cord Plasma Biomarkers of In Utero Acetaminophen Exposure With Risk of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder in Childhood What is the association between cord plasma biomarkers of in utero acetaminophen exposure and risk of childhood attention-deficit/hyperactivity disorder and autism spectrum disorder? In this cohort study of 996 mother-infant dyads from the Boston ... pmc.ncbi.nlm.nih.gov

Effect of prenatal and early life paracetamol exposure on the level of neurotransmitters in rats--Focus on the spinal cord - PubMed The present study has examined the influence of the prenatal and early life administration of paracetamol on the level of neurotransmitters in the spinal cord of rat pups. The effect of the drug was evaluated in 2-month old Wistar male rats exposed to paracetamol in doses of 5 (P5, n=9) or 15 mg/kg … pubmed.ncbi.nlm.nih.gov

Developmental exposure to paracetamol causes biochemical alterations in medulla oblongata - PubMed The effect and safety of prenatal and early life administration of paracetamol - routinely used over-the-counter antipyretic and analgesic medication on monoamines content and balance of amino acids in the medulla oblongata is still unknown. In this study we have determined the level of neurotransmi … pubmed.ncbi.nlm.nih.gov

Sex-specific neurobehavioral and prefrontal cortex gene expression alterations following developmental acetaminophen exposure in mice Acetaminophen (N-acetyl-p-aminophenol (APAP), also known as paracetamol) is one of the most common medications used by the general population, including pregnant people. Although many human observational and animal model studies have shown ... pmc.ncbi.nlm.nih.gov

Early paracetamol exposure decreases brain-derived neurotrophic factor (BDNF) in striatum and affects social behaviour and exploration in rats The biochemical and behavioral responses to prenatal and early postnatal exposure to paracetamol in rats are not well understood. The effect of daily … sciencedirect.com

Acetaminophen’s Role in Autism and ADHD: A Mitochondrial Perspective One in 36 children were identified with autism in 2020, a 22% increase from 2018 and a 98% increase from 2010. Simultaneously, attention-deficit/hyperactivity disorder (ADHD) diagnoses increased 36% from 2003 to 2016–2019. Despite this surge, their ... pmc.ncbi.nlm.nih.gov

Perinatal exposure to paracetamol: Dose and sex-dependent effects in behaviour and brain's oxidative stress markers in progeny - PubMed Paracetamol (PAR) has been employed worldwide for pain and fever treatment during pregnancy and lactation. Epidemiologic studies have shown that exposure to PAR can increase the risk for developmental disorders, such as attention-deficit hyperactive disorder and autism spectrum disorder. This study … pubmed.ncbi.nlm.nih.gov

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@Matee92117372 the studies are on both - children <5 and pregnant women. ibuprofen is safer in this regard

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@SophieRaccoons @JensP573280 there is no sole cause, there are many contributing factors, and if something can cause all of the biochemical changes tylenol can, it's certainly a candidate to be a contributing factor science isn't "junk" because you don't like it

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Posted - September 18, 2025 at 12:23 PM

Saved - September 18, 2025 at 12:57 PM

reSee.it AI Summary

I’ve been exploring the impact of Wi-Fi radiation on testosterone and sperm health, revealing alarming findings from various studies. One study showed that just 2 hours of exposure can damage the seminiferous tubules in testicles and reduce testosterone levels to a third of normal values. Sperm count and viability also decline, with oxidative stress being a key factor in this damage. A systematic review of 19 studies supports these results, suggesting we should limit wireless device usage, although most research is based on animal studies and human trials are unlikely.

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Wi-Fi radiation can have devastating consequences on testosterone and sperm health, as multiple studies have demonstrated. (🧵1/7)

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For example, here's one study examining the impact of just 2 hours of Wi-Fi radiation exposure. The parameters were matched to meet most modern WiFi standards. ◇ 2.45-GHz (frequency) ◇ 64.776 mW (power output) ◇ 0.029812 mW/cm² (power density) ◇ 0.018 W/Kg (specific absorption rate, or how much radiation tissues actually absorb) Keep in mind that both your Wi-Fi router AND your phone put out this type of radiation within these parameters. (2/7)

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Wi-Fi at just 2 hours a day ripped apart the structure of the seminiferous tubules, the main functional unit of the testicles. The diameter of these tubules was smaller and the Leydig cells, which produce testosterone, were also degenerated. (3/7) https://t.co/oLxyV7L8uj

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Wi-Fi also worsened sperm health. Both sperm count and viability were reduced with exposure. Previous studies showed that they could cause DNA damage in these cells, and even hypothesized that putting a laptop on your lap could directly cause this. (4/7) https://t.co/Gz4y4IgitY

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Wi-Fi was able to do this by inducing oxidative and nitrosative stress. Essentially, it causes the production of small but highly reactive molecules made of oxygen and nitrogen. These can cause damage to tissues and alter hormonal / signaling functions. (5/7) https://t.co/I3imeUsXQ2

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Strikingly, testosterone was a THIRD of control values when exposed to Wi-Fi. 2 hours a day, all parameters similar to what you and I get exposed to just by using our phones. (6/7) https://t.co/HSwMVoPfEt

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A recent systematic review of the literature included 19 studies corroborated these findings, concluding that "limiting the use of wireless devices is recommended." It is true that most of these are animal studies, but as we've discussed, the exposure parameters match (or even underestimate) exposures in humans. There won't be any human trials on this, ever, I can almost guarantee you that. The human studies on exposure we do have are very limited, mainly because we're all getting blasted with Wi-Fi all the time. (7/7)

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Studies https://sci-hub.se/10.3109/15368378.2013.869752 https://sci-hub.se/10.3109/10715762.2014.888717 https://pmc.ncbi.nlm.nih.gov/articles/PMC8497974/pdf/fphys-12-732420.pdf

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Posted - August 31, 2025 at 1:52 PM

Saved - September 1, 2025 at 1:03 AM

reSee.it AI Summary

A recent study indicates that grounding enhances metabolism and reduces free radical production in mitochondria. Grounding has multiple benefits, including reduced inflammation and lower blood sugar. The study involved isolated mitochondria connected to the ground via steel and copper wiring. Grounded mitochondria produced less oxidative stress and generated 5-11% more ATP, indicating improved mitochondrial health. The mechanism remains unclear, but grounding may supply free electrons, reducing free radical production and enhancing energy output.

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A new study has shown that grounding boosts metabolism & reduces free radical production in the mitochondria. (🧵1/7)

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This study was published in June. Grounding has shown multiple benefits, including: - Reduction of inflammation - Normalization of cortisol - Decreased fatigue - Lower blood sugar So the goal here was to get a deeper understanding of how. (2/7) https://t.co/QPDkK2kyPV https://t.co/7z9KpFvHcB

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Grounding can transform your health overnight. It rapidly resolves inflammation, improves sleep & lowers stress. These are the BENEFITS of GROUNDING (+ how it works, and how to do it properly):

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This was done by experimenting with isolated mitochondria. They measured how much energy mitochondria could output and how much oxidative stress they would be under. To ground, they literally stuck steel wiring into the tubes with the mitochondria, which connected to the ground via copper wiring. A control group had the wiring but no connection to the ground. (3/7)

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The grounded mitochondria produced substantially less reactive oxygen species under resting (stage 4) + uncoupled (stage 3) conditions. This is a key sign of mitochondrial health and would lead to a reduction in all disease / aging processes. (4/7) https://t.co/pppVAG7Am6

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The grounded mitochondria also churned out about 5-11% more energy in the form of ATP. This is huge - since the mitochondria produces around 90% of your energy. Metabolic boost. (5/7) https://t.co/TjX07kO2qd

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Under active energy production conditions, grounding also lowered oxidative stress (hydrogen peroxide production). Typically when energy production is up we think of the mitochondria putting out more reactive oxygen species. Grounding improves both. (6/7) https://t.co/rTPLceMK7w

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The reason for this effect is unclear. When mitochondria produce energy, they do so by pumping protons across the mitochondrial membrane. This creates a proton gradient or membrane potential. It's possible that grounding, by supplying free electrons from the ground, was able to decrease free radical production and pair up with protons, neutralizing both. This in turn would allow for more energy to be produced due to less mitochondrial damage, energy input, and more ATP output potential. Regardless, this is the first time we have seen a mechanism be proven for the observed benefits of grounding. For it to benefit such a crucial aspect of cellular health + metabolism is massive to say the least. (7/7)

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Posted - August 16, 2025 at 2:55 PM

Saved - August 16, 2025 at 4:23 PM

reSee.it AI Summary

There's a significant chance of having a parasite, with symptoms ranging from bloating and fatigue to anxiety and skin issues. Parasites are prevalent globally, affecting mental health and gut health. They thrive in compromised physical barriers and can be contracted through contaminated water, unwashed produce, or pets. Maintaining a healthy gut microbiome and proper nutrient levels is crucial for resistance. Testing for parasites can involve stool and blood tests, and treatment options include both natural remedies and pharmaceuticals. Personalized help is available for those seeking guidance.

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There's a 50% chance a parasite is in you right now. Here's everything you know about them & how to protect yourself. (🧵1/16)

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SIGNS of a parasite: - Bloating - Gas (especially after meals) - Constipation or diarrhea - Undigested food in stool - Brain fog - Anxiety or irritability - Fatigue - Iron-deficiency anemia - Weight loss or unexplained weight gain - Nutrient deficiencies despite eating well - Histamine intolerance - Food sensitivities - Frequent infections - Skin rashes or itching - Muscle or joint pain All of these symptoms can be indicative of, but are not exclusive to, parasites. The KEY indicators that should make you think parasite over other factors: ☆ Itchiness - especially your butt ☆ Symptoms worsening at night (1-3 AM) ☆ Worsening at full moons ☆ Symptoms appear after traveling (esp to southeast Asia, Africa, caribbean) ☆ Teeth grinding ☆ You see worms in your poop (2/16)

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Parasites are highly prevalent in mental + cognitive disorders. A new meta-analysis showed that people with mental health disorders have 2x higher odds of protozoan infection. ~25% infected overall. Up to 34% in neurodevelopmental + bipolar disorders. (3/16)

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And yes, estimates routinely put global parasite prevalence at around 3.5 billion people. The primary types are worms and protozoa. Ascaris lumbricoides (roundworm) ➜ 800M–1.2B Trichuris trichiura (roundworm/whipworm) ➜ 600M–800M Hookworms (Necator americanus, Ancylostoma duodenale) ➜ 500M–700M Entamoeba histolytica (protozoa) ➜ ~500M Giardia lamblia (protozoa) ➜ 200M–300M Other protozoa (Cryptosporidium, Blastocystis, etc.) ➜ 100M–300M (4/16)

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Even if you don't have any acute symptoms, parasites are still harming your health. Even if YOU don't know you have them, your body does. They can: ◇ Trigger inflammation in the brain ◇ Alter gut bacteria ◇ Increase leaky gut ◇ Drive neuroinflammation / brain cell death ◇ Steal nutrients & more. The optimal amount of parasites in your body is zero. (5/16)

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But how do you get exposed to parasites? Parasites cannot live on their own, they live by sucking the life out of other organisms, so if you get infected it'll be from another organism. ➜ Contaminated water ➜ Any other exposure to feces ➜ Unwashed produce ➜ Soil ➜ Undercooked seafood / meat ➜ Pets (dogs + cats) A lot of these are much less common in developed countries, so traveling to a less developed country is a common way to get exposed. Here's a brief guide on some of the most important ones and how you can get exposed⬇️ (6/16)

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Now, we're all constantly exposed to parasites. The question is, what makes one person susceptible to actually getting infected? One of the most important things is ensuring your physical barriers are set up for success, mainly your: ➠ Gut ➠ Skin ➠ Urethral / vaginal If these are impaired, parasites have free reign to enter your body and cause issues. Some important factors for maintaining it: ➥ Zinc, vitamins A & D (cell differentiation, antimicrobial) ➥ Vitamin C (collagen synthesis) ➥ Adequate butyrate production (tight junction proteins) ➥ Lysine (collagen cross linking) ➥ Collagen (constituent amino acids, peptides stimulate collagen production) ➥ Keeping the gut clean with healthy bacteria ➥ Reducing oxidative stress (which drives inflammation, disrupts tight junction synthesis) ➥ Keeping cortisol in check (CRH from HPA axis weakens barriers) (7/16)

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An interesting note is that parasites tend to accumulate lots of heavy metals. This means that heavy metal toxicity and parasitic infections often go hand in hand. Based on our experience with clients, we've seen that incorporating sufficient minerals, which can help displace heavy metals, results in excretion of parasites. (8/16)

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I wrote a master thread on understanding and detoxing from heavy metals below.

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The poisons WRECKING your health that your doctor doesn’t want to talk about. This is the COMPLETE GUIDE to TOXIC HEAVY METALS - how you get exposed, sick, and what to do about it:

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The gut microbiome is also vital for resistance to parasites. They're constantly interacting. Healthy microbes can suppress their growth and keep the gut barrier sealed, so parasites can't penetrate our defenses. Pathogens however can promote the hatching of their eggs, meaning they spread faster. In fact, antibiotics have been shown in certain instances to prevent egg hatching. (9/16)

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Serotonin also stimulates parasitic growth. Serotonin is mainly produced in the gut in response to irritation and pathogenic bacteria. More on that below. (10/16)

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YOU MUST ADDRESS THIS TO FIX YOUR GUT This “happy hormone” is the primary driver of digestive problems. I found that out the hard way. Here’s what I’ve learned, how I lowered it and how you can do the same:

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Here are a few of the master guides I've put together on each of these topics. Master gut health guide

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READ THIS IF YOU WANT TO FIX YOUR GUT. If you have IBS, bloating, gas, poor bowel movements or brain fog, you NEED to see this. This is a comprehensive DEEP dive into fixing your digestive health:

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Guide on keeping cortisol in check

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High cortisol, anxiety, and can’t sleep? This is for you. This is the ULTIMATE GUIDE to STRESS - the signs, the biological mechanisms and what to do about it:

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The thyroid is vital for proper immunity, including that against parasites. Master thyroid guide below.

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The key to unlocking your metabolism, mood, energy and gut health is sitting under your tongue being ignored by your doctor. This is the ULTIMATE AND COMPLETE GUIDE TO THYROID HEALTH so you can optimize it:

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Other issues can leave you susceptible to parasitic infection. For example, mycotoxins from mold can drive inflammation while simultaneously contributing to immune suppression, which can make it easier for parasites to invade. More on mold below.

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MOLD: The hidden cause behind your gut issues & fatigue that your doctor can't figure out. This is a DEEP dive on mold / mycotoxins - how to know if it's an issue for you and what to do about it to get back to feeling your best:

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Parasites are highly circadian dependent. Most parasites have fluctuations in their activity + abundance throughout the day. Meanwhile, our own: ◇ Body temperature ◇ Immune cell populations ◇ Melatonin depend on the time of day as well. Maintaining a proper circadian rhythm ensures that these factors are peaking and dipping at their correct times. If your circadian rhythm is off, your body can't distinguish time of day, and your normal immune defenses are awry. The most important factors for the circadian rhythm are: ◇ Waking up and sleeping aligned with the sun ◇ Bright morning sunlight in the morning ◇ Keeping your sleep / wake times consistent ◇ Eating at the same times daily. (11/16)

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Another thing to understand with parasites is their life cycle, particularly for worms. As mentioned previously, worms lay eggs, and once these eggs hatch they are first larvae before fully grown worms. ➜ When eggs are laid, symptoms tend to flare (eggs are highly inflammatory) ➜ When they hatch, and larvae emerge, they tend to migrate, which can also lead to more symptoms Ironically, the fully developed adult worm, while being much larger, is when symptoms tend to be less noticeable. It is also in this adult phase that antiparasitics should be employed, as the eggs are much more resistant to them. The entire life cycle can take several weeks. So not only will you have symptoms cycling throughout the day due to the circadian rhythm, you'll also have them cycling week to week depending on egg status. These are key ways to know if you might have them. (12/16)

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TESTING FOR PARASITES: There are a few types of tests: ➜ Ova & Parasite (stool test, looks for eggs and mature parasites) ➜ Antigen testing (stool, highly sensitive) ➜ PCR (stool, highly sensitive) ➜ Antibody testing (less common, less reliable) While panels of multiple exist, each type of parasite has a test that identifies it best. Here's some of the most common ones⬇️ (13/16)

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There are also clues on standard / common blood tests that might be able to help identify parasites. The most common is likely high eosinophils, since these are the immune cells that primarily kill parasites. Here are some other signs, specific for certain parasites⬇️ (14/16)

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Finally, we have antiparasitics. Here are some of the natural tools often used, each specializing in different species. These are less powerful than pharma options, but are easier to obtain. (15/16)

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Here are the pharmaceutical options. It's important to remember for these and for natural options to dose around their life cycle (not while there are eggs). Sometimes, multiple doses are needed. Some of these (metronidazole) can act as antibiotics as well, something to keep in mind. (16/16)

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All of this can be difficult to sort out on your own, but you don't have to. We have experience helping people with this & countless other issues. If YOU want PERSONALIZED, IN DEPTH help from us with any of your health goals, schedule a free call here: https://go.prism.miami/consultation

Schedule a Free Call with Prism Health Book your free consultation to optimize your health, energy, and vitality. prism.miami

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sources https://gutpathogens.biomedcentral.com/articles/10.1186/s13099-024-00602-2 mental Long term impacts - even if no acute symptoms https://www.mdpi.com/2076-0817/13/8/608 steals nutrients, TLR, etc https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.1024998/full brain More on prevalence - breakdown of types https://pmc.ncbi.nlm.nih.gov/articles/PMC8397551/ Types / exposure sources https://www.sciencedirect.com/science/article/pii/S0893395223001229 What determines susceptibility (risk factors)? What environments do they like? Heavy metals https://www.cell.com/trends/parasitology/fulltext/S0169-4758(98)01358-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0169475898013581%3Fshowall%3Dtrue https://www.sciencedirect.com/science/article/pii/S0166445X11002980 https://pmc.ncbi.nlm.nih.gov/articles/PMC7476227/ Bacteria Bacteria needed for egg hatch - Abx prevent - other https://pmc.ncbi.nlm.nih.gov/articles/PMC11356857/ serotonin https://pmc.ncbi.nlm.nih.gov/articles/PMC6920103/ https://www.nature.com/articles/s41598-017-11297-8 - morning lowers susceptibility https://sci-hub.se/10.1016/S0140-6736(68)91469-4

A systematic review and meta-analysis of protozoan parasite infections among patients with mental health disorders: an overlooked phenomenon - Gut Pathogens Patients with mental disorders have a high risk of intestinal parasitic infection due to poor hygiene practices. Hence, to better clarify this overlooked phenomenon, the current study is conducted to determine the global prevalence of protozoan parasite infections in patients with mental disorders and investigate the associated risk factors. Several databases (PubMed, Scopus, Web of Science, ProQuest, and Google Scholar) were searched for papers published until December 2022. The fixed effect meta-analysis was used to estimate the overall odds ratio (OR) and pooled prevalence was estimated using a random-effects model with a 95% confidence interval (CI). Totally, 131 articles (91 case–control and 40 cross-sectional studies) met the eligibility criteria. Patients with mental disorders were significantly at higher risk for protozoan parasites than healthy controls (OR: 2.059, 1.830–2.317). The highest pooled OR (2.485, 1.413–4.368) was related to patients with neurodevelopmental disorders, and the highest pooled prevalence was detected in patients with neurodevelopmental disorders (0.341, 0.244–0.446), followed by bipolar and related disorders (0.321, 0.000–0.995). Toxoplasma gondii was the most prevalent protozoan parasite (0.343, 0.228–0.467) in cross-sectional studies and the highest pooled OR was related to Cyclospora cayetanensis (4.719, 1.352–16.474) followed by Cryptosporidium parvum (4.618, 2.877–7.412). Our findings demonstrated that individuals afflicted with mental disorders are significantly more susceptible to acquiring protozoan parasites in comparison to healthy individuals. Preventive interventions, regular screening, and treatment approaches for parasitic diseases should be considered for patients with mental disorders. gutpathogens.biomedcentral.com

Frontiers | Parasite infections, neuroinflammation, and potential contributions of gut microbiota Many parasitic diseases (including cerebral malaria, human African trypanosomiasis, cerebral toxoplasmosis, neurocysticercosis and neuroschistosomiasis) feat... frontiersin.org

Prevalence of Intestinal Parasite Infections and Their Associated Factors among Food Handlers Working in Selected Catering Establishments from Bule Hora, Ethiopia Intestinal parasites are responsible for one of the major health problems like food contamination with socioeconomic effects in the world with a prevalence rate of 30-60%, in developing countries that lie within tropical and subtropical areas. They ... pmc.ncbi.nlm.nih.gov

The Landscape of Parasitic Infections in the United States The landscape of parasitic infections in the United States has shifted dramatically over the past century. Although infections such as malaria have be… sciencedirect.com

Parasites modify sub-cellular partitioning of metals in the gut of fish Infestation of fish by parasites may influence metal accumulation patterns in the host. However, the subcellular mechanisms of these processes have ra… sciencedirect.com

Heavy metals, parasitologic and oxidative stress biomarker investigations in Heterotis niloticus from Lekki Lagoon, Lagos, Nigeria Occurrence of parasites in fish could bio accumulate heavy metals by as much as 200 % more than values present in fish tissues. Parasitic infection in fish is positively skewed towards male fish. Parasitism in fish alters histological structures of ... pmc.ncbi.nlm.nih.gov

Interaction between Intestinal Parasites and the Gut Microbiota: Implications for the Intestinal Immune Response and Host Defence Intestinal parasites, including helminths and protozoa, account for a significant portion of the global health burden. The gastrointestinal (GI) tract not only serves as the stage for these parasitic infections but also as the residence for millions ... pmc.ncbi.nlm.nih.gov

The Complex Interplay of Parasites, Their Hosts, and Circadian Clocks Parasites have evolved various mechanisms to favor infection of their hosts and enhance the success of the infection. In this respect, time-of-day effects were found during the course of parasitic infections, which can be caused or controlled by ... pmc.ncbi.nlm.nih.gov

The circadian clock in immune cells controls the magnitude of Leishmania parasite infection - Scientific Reports The intracellular parasite Leishmania uses neutrophils and macrophages as host cells upon infection. These immune cells harbour their own intrinsic circadian clocks, known to influence many aspects of their functions. Therefore, we tested whether the host circadian clocks regulate the magnitude of Leishmania major infection in mice. The extent of parasitic infection varied over 24 h in bone marrow-derived macrophages in vitro and in two different in vivo models, footpad and peritoneal cavity infection. In vivo this was paralleled by time of day-dependent neutrophil and macrophage infiltration to the infection site and rhythmic chemokine expression. Thus, rhythmic parasitic infection observed in vivo was likely initiated by the circadian expression of chemoattractants and the subsequent rhythmic infiltration of neutrophils and macrophages. Importantly, all rhythms were abolished in clock-deficient macrophages and when mice lacking the circadian clock in immune cells were infected. Therefore we demonstrated a critical role for the circadian clocks in immune cells in modulating the magnitude of Leishmania infection. To our knowledge this is the first report showing that the circadian clock controls infection by protozoan parasites in mammals. Understanding the timed regulation of host-parasite interactions will allow developing better prophylactic and therapeutic strategies to fight off vector-borne diseases. nature.com

Sci-Hub | | 10.1016/s0140-6736(68)91469-4 sci-hub.se

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@ImmuneNaturally that certainly sounds like it especially with the cyclic nature of symptoms

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Posted - July 30, 2025 at 9:55 PM

Saved - July 31, 2025 at 12:25 AM

reSee.it AI Summary

I’ve discovered five science-backed tools that can help melt off fat without changing my diet. 1. Coconut oil can reduce belly fat, with about 2.5 tsp daily shown to help. 2. Vinegar, particularly apple cider vinegar, can target abdominal fat and improve metabolic health with just 1-2 tbsp daily. 3. Zinc supplementation (30 mg/day) aids in fat loss and restores insulin sensitivity. 4. Sunlight exposure, especially UV light, enhances fat loss and metabolic function. 5. DHEA, at 50 mg daily, can reduce belly fat and improve insulin resistance as we age.

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Here are 5 tools that melt off fat, without even changing your diet, backed by actual science. #1 COCONUT OIL Coconut oil has been studied to directly reduce belly fat / waistline vs other fats. Coconut oil reduces waistline, without reducing calories. Adding ~2.5 tsp/day to the diet over 3 months in one study. The shorter chain fats in coconut oil get rapidly burned for energy - they almost never get stored for energy, unlike other fats we eat. #2 Vinegar Vinegar sheds abdominal fat. 1-2 tbsp / day was shown to target fat around the belly. 6 tsp of apple cider vinegar per day: • Reduced weight by 5.5 lb • Lowered blood sugar • Reduced waist circumference It also: • Lowers triglycerides • Improves insulin sensitivity • Increases glycogen storage in a recent study. HOW VINEGAR SHEDS BELLY FAT: Vinegar has acetic acid - which is uniquely metabolized compared to most things we consume. It activates AMPK - cellular regulator that: ◈ Turns on PGC1α - activating mitochondrial biogenesis ◈ Increases GLUT4 - which increases sugar metabolism ◈ Suppresses fat synthesis Acetic acid also works in the brains' hypothalamus to regulate metabolism. It acts as a genetic regulator (acetylates histones) - lowering inflammation and oxidative stress in the hypothalamus. This improves leptin resistance, and thus increases metabolism. #3 Zinc Zinc can induce fat loss, without changing diet. 30 mg a day: ➔ Reduces waistline ➔ Drops bodyweight ➔ Lowers triglycerides Zinc is one of the most common depletions in obesity, and is vital in restoring insulin / leptin sensitivity through multiple actions. Another study confirmed that zinc induces weight loss, without further cutting calories. Adding 30 mg zinc sulfate to a diet: ◇ Increases weight loss by ~7 lbs ◇ Reduces waistline ◇ Decreases blood sugar ◇ Reduces insulin Zinc also is vital for thyroid hormones - which increase metabolism. #4 Sunlight The sun emits light with numerous different wavelengths that induce fat loss. Multiple animal experiments have shown that UV light does - independently of vitamin D. • Reduces body fat gain, even on a fattening diet • Normalizes blood sugar • Reverses fatty liver It enhances mitochondrial metabolism. Red light therapy also melts belly fat. Applying an LED light at: ◇ 630 + 850 nm ◇ 2x weekly ◇ 2-3 mins / session ◇ 5 weeks Reduced thickness of abdominal fat in all measured areas. These lights penetrate the skin & stimulate mitochondrial function in the fat cells. Blue light sheds fat. Fat tissue has blue light absorbing proteins that: ⬩Increase metabolism + heat generation ⬩Reduce body fat (without reducing calories) ⬩Improve glucose tolerance ⬩Lower insulin levels through neural connection to the brain. Another component of sunlight. #5 DHEA DHEA is a steroid that declines by >80% with age, contributing to belly fat accumulation over time. 50 mg / day: ◇ Reduces body fat percentage ◇ Reduces belly fat ◇ Lowers inflammation ◇ Lowers blood sugar ◇ Lowers insulin DHEA sheds belly fat. 50 mg / day in another study showed reduced abdominal fat + improved insulin resistance. DHEA: ➜ Lowers / opposes cortisol (which increases belly fat) ➜ Is a sex steroid precursor ➜ Ups IGF-1 ➜ Increases PPARα (improves fat metabolism) in older folks.

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Posted - July 28, 2025 at 12:54 PM

Saved - July 29, 2025 at 8:19 AM

reSee.it AI Summary

A study published in 2021 found that daily vinegar consumption significantly improved depression scores by over 50% among healthy college students. Participants consumed two tablespoons of apple cider vinegar dissolved in water twice daily for four weeks, leading to a 31.4% improvement in depression scores compared to a control group. Researchers identified changes in 17 metabolites linked to vinegar's effects, suggesting potential biochemical pathways involved in mood enhancement, including the hexosamine pathway and cystathionine metabolism.

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A fascinating study shows that daily vinegar consumption improves depression scores by >50%. (🧵1/8)

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This study came out in 2021 in the journal of Nutrients. Vinegar has several beneficial effects metabolically. Metabolism and mood are deeply intertwined - so researchers sought to find out if vinegar had direct antidepressant qualities. (2/8)

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Depression isn't some unknown genetic condition like your doctor tells you. In fact, we know the exact biological causes behind it. Here are 10 hallmarks of depression, & what you might be able to do about each:

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WANT TO GET MORE OUT OF LIFE? Stuck in a routine of monotony? No motivation? Like there’s no point of trying for more? There’s a biological cause (and solution) to this and it isn’t what you expect THREAD 🧵

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Participants were college students. They also excluded obese individuals, or anyone with other underlying illness. Thus, the population was already relatively young and healthy - meaning any effect of vinegar had to be strong in order to move the needle. (3/8)

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The vinegar group consumed: ➜ 2 tablespoons of apple cider vinegar (Bragg's) ➜ Dissolved in a cup of water ➜ Twice daily ➜ With meals ➜ For 4 weeks Participants were randomized and the control group was given very low dose "vinegar pills" - so they wouldn't know they were in the placebo group. (4/8)

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Vinegar was strikingly effective for depression. CES-D (depression) scores improved by 31.4% in the vinegar group, while worsening by 23.7% in the control group, meaning a ~58% overall improvement. This was consistent with the other survey of depression (POMS depression) - so the effect was real. (5/8)

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Vinegar also seemed to (though not "statistically" significant): ◇ Improve overall mood ◇ Reduce tension ◇ Reduce anger ◇ Reduce fatigue ◇ Improve vigor Pretty incredible for something so ubiquitous and cheap. (6/8)

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To better assess why vinegar was able to have these mood improving effects, the researchers collected urine and analyzed over 900 metabolites. 17 of them were found to be changed by vinegar. (7/8)

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Knowing the amounts of all of these metabolites, they were also able to analyze what biochemical pathways & enzymes were important to vinegar's effect as well. Pathways of interest included: ◈ The hexosamine pathway ➞ a pathway that turns sugar into glycans, often upregulated in diabetes / insulin resistance. High glycans can influence neurotransmission / plasticity as well. ◈ Cystathionine metabolism ➞ important for glutathione synthesis (antioxidant status), which is often low in depression. These are just a few of the mechanisms potentially behind the mood enhancing abilities of vinegar. (8/8)

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Read the full study here: https://pmc.ncbi.nlm.nih.gov/articles/PMC8622118/

Daily Vinegar Ingestion Improves Depression Scores and Alters the Metabolome in Healthy Adults: A Randomized Controlled Trial Daily vinegar ingestion has been linked to improved glycemic control, but recent data suggest a separate unexplored role for vinegar in mental health. Utilizing a placebo-controlled, parallel arm study design, this 4-week trial examined the impact ... pmc.ncbi.nlm.nih.gov

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I've also just done a full video on the various benefits and mechanisms behind vinegar: https://youtu.be/CS1eL10gkXc

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Vinegar is a fantastic way to upgrade your health - but if you want to fully optimize, a more comprehensive approach would be optimal. If YOU want PERSONALIZED, IN DEPTH help from us with any of your health goals, schedule a free call here: https://go.prism.miami/consultation

Schedule a Free Call with Prism Health Book your free consultation to optimize your health, energy, and vitality. prism.miami

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Posted - April 15, 2025 at 2:13 PM

Saved - July 29, 2025 at 6:05 AM

reSee.it AI Summary

Coconut oil is highlighted for its numerous health benefits, including anti-inflammatory properties, weight management, and improved immunity. It has shown effectiveness in reversing inflammatory bowel disease, reducing waistlines, preventing obesity, and enhancing male fertility. Research indicates it can lower inflammation in COVID-19, improve HIV immunity, and combat bacterial and fungal infections. Additionally, coconut oil may protect against brain aging, liver damage from chemotherapy, and kidney issues, while also improving heart disease risk markers.

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This stuff is borderline magical. The benefits are seemingly endless - it sheds fat, anti-inflammatory, cognitive enhancing, antimicrobial. Wanna hear about MORE of the unbelievable benefits & research of COCONUT OIL? Of course you do, let's get into it:

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The anti-cancer, metabolism boosting and cognitive enhancing tool that's been hiding in your cabinet. COCONUT OIL is simply a marvel for your health, here's why:

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Coconut oil reverses inflammatory bowel disease: On all of standard drugs, no progress. Rejected surgery, tried coconut oil enemas. 6 months later, the colon looked normal, and symptoms subsided. Really demonstrates the anti-inflammatory power of coconut oil.

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Coconut oil reduces waistline. Adding ~2.5 tsp/day to the diet over 3 months, without reducing calories. This is likely due to the MCTs in coconut oil - fats that are burned rapidly and do not get incorporated into fat easily.

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Coconut oil prevents obesity, diabetes, and fatty liver. A high soybean oil diet: ⇨ Induces fat gain ⇨ Increases blood sugar ⇨ Impairs insulin sensitivity ⇨ Increases liver fat accumulation Coconut oil does not - due to the high MCT / saturated fat content.

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Coconut oil lowers inflammation in COVID, supports immunity. 3 tbsp / d for 28 days: • ↓ CRP • ↓IL-6 (inflammatory markers) • ↑ CD4+ T cells • ↑ Natural killer cell activity (immune cells) Monolaurin from coconut oil has direct antiviral properties.

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Coconut oil improve immunity in HIV. HIV can deplete CD4+ T-cells, weakening immunity, but 45 mL (3 tbsp) coconut oil daily for 6 months significantly increased them. No adverse effects or toxicity - probably due to reduced viral replication.

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Coconut oil is excellent for male fertility Here it reverses the damage from excess alcohol consumption: • ↑ Sperm count • ↑ Sperm motility • Preserves testicular structure • ↑ Glutathione (antioxidant) • ↓ MDA (oxidative damage)

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Coconut oil reverts damage from endocrine disruptors. Synthetic chemicals can mess with your reproductive system, but coconut oil combats this: • RAISES testosterone • Protects testicles from damage • Restores sperm counts, motility • Lowers estrogen • Lowers prolactin

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Seed oils lower testosterone - coconut oil raises it. ➜ Increases test producing enzymes ➜ Raises cholesterol in the testicles ➜ Protects against testicular oxidative damage A huge piece of the low T epidemic.

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90% of men are low on testosterone nowadays, and the problem is only getting worse. But what should we do about it? This is your FULL GUIDE to TESTOSTERONE - the fundamentals you MUST address to optimize your levels:

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Coconut oil also has powerful antimicrobial properties. This man was given 1-2 tbsp for 15 days and saw a complete recovery from H. Pylori. Negative IgG, no more symptoms. Also has anti-ulcer activity.

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Coconut oil is an alternative to proton pump inhibitors (PPIs). ◎ Stopped stomach ulcers ◎ Increased the mucus of the stomach lining ◎ Enhanced production of healing prostaglandins ◎ Stopped the stress-induced hyper-secretion of acid Could be good for reflux.

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Coconut oil pulling reduces dental plaque. The fats in coconut oil are unique for their antibacterial & antifungal properties. Coconut oil also directly breaks up the biofilms that create the plaques in the mouth. 10 minutes. Swish. Spit. You are golden.

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Coconut oil pulling improves gingivitis by over 50%. The fats in coconut oil: ➟ Breaks up plaque ➟ Kills primary gingivitis causing bacteria ➟ Calm inflammation resulting in a rapid improvement in this condition - under one month of daily pulls.

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Virgin coconut oil even kills Staph bacteria. In multiple antibiotic resistant strains, it inhibited growth of Staphylococcus aureus. Lauric acid, a fat in coconut oil, destroys bacterial cell membranes and improves the immune response.

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Coconut oil reverses fungal (Candida) overgrowth. Compared with diets high in: ↣ Tallow ↣ Soybean oil Coconut oil lowers Candida colonization in all parts of the GI tract. This is due to the shorter chain fats in coconut oil, which have antifungal properties.

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Coconut oil reverses brain damage from Alzheimer's plaques. ◈ Prevents deterioration of cell structure ◈ Preserves synaptic vesicles for neurotransmission in large part due to its MCTs - fats that support the brain's metabolism, which becomes impaired in cognitive decline.

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Coconut oil prevents aging of the brain. Virgin coconut oil has routinely been shown to keep the brain young. • ↓ Amyloid plaques + tau tangles • ↓NLRP3, IL-1β (brain inflammation) • Preserves hippocampal neuron integrity • Improves spatial learning and memory

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Alzheimer's prevalence is set to double in the next 25 years. Yet, mainstream treatments have been complete and utter failures. Probably because they don't fundamentally understand the problem. Here's what really behind it, and what you might be able to do about it:

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Coconut oil actually improves Alzheimer's disease. ~1.5 tbsp / day showed improvements in >80% of patients over 6 weeks. Crazy.

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Coconut oil prevents chemo induced liver damage. In general coconut oil has a protective effect on inflammatory / toxic insults to tissues: • ↓ ALT + AST (liver tissue breakdown) • ↓ TNF-α + IL-6 (inflammation) • Preserves liver cell structure

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Coconut oil for 4K vision. The retina is susceptible to energy deprivation + damage from light, causing worse vision with age. Coconut oil is actually able to reduce inflammatory gene expression & oxidative stress in retina.

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Coconut oil prevents kidney damage. A common cause of kidney disease is consuming fried oils, but coconut oil: • ↓ Blood pressure elevation • ↓ Kidney damage and inflammation • ↑ Antioxidant enzyme activity (SOD, catalase) again, due to its saturated fats + phenolics.

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Coconut oil improves bone structure, even better than calcium. Deterioration of bone is an active process driven by oxidative stress and inflammation. Coconut oil is able to restore bone volume to a normal level after "menopause" - where these factors normally decimate bones.

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Coconut oil also improves heart disease risk markers. Controlled feeding vs. other common fats. • ↓ Lipoprotein(a) - a plaque driving cholesterol carrier • ↓ tPA - increased clotting • ↑ HDL cholesterol Broad acting benefits for metabolic health.

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Coconut oil is absolutely fantastic, but getting to optimal health goals will certainly require more. If YOU want personalized help from us with your health, click where it says “schedule free consultation” here: http://prism.miami

Prism Health The solution is out there. We can help you find it. prism.miami

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Thank you for reading through this. Give this tweet below a repost if you found it interesting to spread the message.

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This stuff is borderline magical. The benefits are seemingly endless - it sheds fat, anti-inflammatory, cognitive enhancing, antimicrobial. Wanna hear about MORE of the unbelievable benefits & research of COCONUT OIL? Of course you do, let's get into it:

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The anti-cancer, metabolism boosting and cognitive enhancing tool that's been hiding in your cabinet. COCONUT OIL is simply a marvel for your health, here's why:

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Be sure to check out all of our content, supplements, lab testing options and join our email list for exclusive offers here: http://www.analyzeandoptimize.io

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SOURCES https://www.ijam.co.in/index.php/ijam/article/view/1215/586 1-2 tbsp cures H pylori, reduces all symptoms pulling https://pmc.ncbi.nlm.nih.gov/articles/PMC6817632/ antibacterial for staph reverses candida overgrowth https://pmc.ncbi.nlm.nih.gov/articles/PMC8142857/ lowers CRP in COVID - due to lauric acid / monolaurin which disrupts viral envelopes, inhibits viral maturation, improves CD4 NK response, altering host membrane fluidity https://journal.coconutcommunity.org/index.php/journalicc/article/view/46 raises CD4 T cells in HIV due to antiviral effect test https://onlinelibrary.wiley.com/doi/epdf/10.1111/andr.12490 improved sperm count + motility, testicular structure and antioxidant status (GSH, MDA) endocrine https://www.sciencedirect.com/science/article/pii/S0278691518302886?ref=pdf_download&fr=RR-2&rr=930456d8192f3458 decreases plaques, preserves hippocampal neurons, decreases tau hyperphosphorylation, reduced neuroinflammation (IL-1B), oxidative stress, improves learning + memory due to lauric acid, phenolics, MCTs alz https://pmc.ncbi.nlm.nih.gov/articles/PMC9920521/pdf/nutrients-15-00564.pdf decr triglyceride, calories by 400 diabetes /NAFL waistline https://sci-hub.se/10.1093/jn/133.11.3422 lowers tPA, Lp(a) https://sci-hub.se/10.1139/apnm-2016-0029 prevents kidney injury, oxstr, blood pressure increase via antioxidant https://pubmed.ncbi.nlm.nih.gov/28068634/ prevents chemo liver injury https://sci-hub.se/10.1016/j.pathophys.2018.10.001 prevents retinal degeneration colitis bone

Antibacterial and immunomodulator activities of virgin coconut oil (VCO) against Staphylococcus aureus Antibiotics have components to inhibit infections against Staphylococcus aureus, but they depend on judicious use to minimize the incidence of resistance forms. Strategies to improve the current situation include research in finding a new ... pmc.ncbi.nlm.nih.gov

Virgin coconut oil is effective in lowering C-reactive protein levels among suspect and probable cases of COVID-19 Keywords: COVID-19, Virgin coconut oil, C-reactive protein, Lauric acid, Monolaurin pmc.ncbi.nlm.nih.gov

Virgin coconut oil (VCO) by normalizing NLRP3 inflammasome showed potential neuroprotective effects in Amyloid-β induced toxicity and high-fat diet fed rat Both dyslipidemia and Alzheimer disease (AD) are associated with aging. In this study, the effects of virgin coconut oil (VCO) on inflammasome and oxi… sciencedirect.com

Sci-Hub | | 10.1093/jn/133.11.3422 sci-hub.se

Sci-Hub | | 10.1139/apnm-2016-0029 sci-hub.se

Virgin coconut oil supplementation attenuates acute chemotherapy hepatotoxicity induced by anticancer drug methotrexate via inhibition of oxidative stress in rats - PubMed The study suggests antioxidant and hepatoprotective effects of VCO supplementation against hepatotoxicity and oxidative damage via improving antioxidant defense system in rats. Our findings may have beneficial application in the management of hepatotoxicity associated with MTX cancer chemotherapy. pubmed.ncbi.nlm.nih.gov

Sci-Hub | | 10.1016/j.pathophys.2018.10.001 sci-hub.se

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Coconut oil reverses fungal (Candida) overgrowth. Compared with diets high in: ↣ Tallow ↣ Soybean oil Coconut oil lowers Candida colonization in all parts of the GI tract. This is due to the shorter chain fats in coconut oil, which have antifungal properties.

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The anti-cancer, metabolism boosting and cognitive enhancing tool that's been hiding in your cabinet. COCONUT OIL is simply a marvel for your health, here's why:

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Posted - June 7, 2024 at 1:33 PM

Saved - July 29, 2025 at 5:53 AM

reSee.it AI Summary

Coconut oil is highlighted for its numerous health benefits, including anti-cancer properties, metabolism enhancement, and cognitive support. It can reduce cancer cell growth while protecting healthy cells, prevent obesity, and improve metabolic rates. Coconut oil also shows promise in reversing brain damage from Alzheimer's, alleviating depression, and aiding in neurogenesis. Additionally, it possesses antibacterial and antifungal properties, supports digestion, prevents cavities, and improves skin health. Its unique medium-chain fats contribute significantly to these benefits.

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The anti-cancer, metabolism boosting and cognitive enhancing tool that's been hiding in your cabinet. COCONUT OIL is simply a marvel for your health, here's why:

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You are looking at the death of cancer cells just with virgin coconut oil (b & d). Coconut able is able to substantially reduce cancer cells but protect healthy cells, something that can't be said for most cancer treatments.

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Including coconut fats / extracts in the diet of animals almost completely prevented skin tumors. It drastically increased the antioxidant levels in various tissues, and has direct tumor suppressing properties. It's shown this property in oral and liver cancers as well.

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Animals stay remarkably lean simply by swapping out a chunk of their seed oils for COCONUT OIL. Despite eating the same amount of calories. (Coconut oil on left, seed oil on right)

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Yes, coconut oil prevents obesity. Adding small amounts of coconut oil: • Stops fat gain • Increased metabolic rate, body temperature • Reversed insulin resistance in animals fed a fattening diet.

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Adding 2 tbsp of coconut oil to the diet was able to reduce waist circumference. The unique fats coconut oil is rich in: ⬩Get absorbed rapidly ⬩Get burned rapidly for fuel ⬩Do not get deposited as fat No other fat has this ability.

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Famously, in Dr. Puppin's book, he tells the story of how farmers literally tried to fatten up pigs using coconut oil, but it just made them lean and energetic. So they switched to seed oils.

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Coconut oil reverses brain damage from Alzheimer's plaque. Coconut oil: ⬩Improved cell survival ⬩Retained mitochondrial structure ⬩Bolstered energy production In neurons exposed to the amyloid plaque. It is remarkably protective for the brain.

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Coconut oil fats multiply mitochondria. C10 found mainly in coconut oil enhances mitochondrial energy production AND number. This is a large part of what gives coconut oil huge benefits for the brain: it enhances its energy production.

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Just a few tsp of coconut oil per day improved multiple metrics of memory in even severe Alzheimer's disease. The medium chain fats in coconut oil are a rapid energy producing fuel source for the brain.

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Coconut oil reverses depression. Virgin coconut oil (VCO): ⬩Prevents neuroinflammation ⬩Alleviates death of neurons ⬩Reverses depressive symptoms in animals with endotoxemia (LPS) (gut bacterial toxicity), through its incredible pro-mitochondrial properties.

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Coconut oil for seizures. The keto diet has long been known to help in epilepsy, but it has recently been shown that it is the medium chain fats (abundant in coconut oil) that protect against seizures, not as much the ketones.

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Coconut oil for neurogenesis. A recent study showed that not only did coconut oil improve insulin resistance, it increased the levels of BDNF, the primary protein responsible for repairing and growing brain cells.

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Coconut oil has antibacterial and antifungal properties. Caprylic acid from coconut oil is highly effective against several pathogenic bacteria an even yeast like Candida.

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Coconut oil is also fantastic for digestion. It robustly lowers gut inflammation. 1-2 tsp equivalent dose, coconut oil reversed IBD disease activity, healed the structure of the gut, lowered: ‣ IL-6 ‣ NO ‣ TNFα ‣ MPO all key components of human gut inflammation.

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Coconut oil is an alternative to proton pump inhibitors (PPIs). ◎ Stopped stomach ulcers ◎ Increased the mucus of the stomach lining ◎ Enhanced production of healing prostaglandins ◎ Stopped the stress-induced hyper-secretion of acid Could be good for reflux.

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Coconut oil is excellent for cavity prevention. Rinsing with it for 10 min (A) reduced the amount of S. Mutants (primary cavity-causing bacteria) as well as the "gold standard" antiseptic mouthwash (B). Your dentist doesn't even know this exists.

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Coconut oil is incredible for the skin. Applying 5 ml of coconut oil 2x daily to the effected areas reduced eczema rating by nearly 69% by: ◎ Increasing skin hydration ◎ Calming inflammation ◎ Bolstering antioxidant status in the skin 🥥

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Coconut oil is a male sexual health Godsend. - REVERSES testicular damage - Improves sperm motility - Bolsters testicular antioxidant status Just incredible.

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What makes coconut oil special is the medium chain fats. Unlike most calories, these get RAPIDLY + EASILY turned into energy. They also are able to fuel the brain (other fats can't). Thus, it serves as a quick, efficient energy source that isn't liable to be stored.

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Coconut oil also has unique phenolic compounds. Most of the studies shown here were done with virgin, unrefined coconut oil, which seems to have compounds that exert many of these biological effects. It's the type I use and is likely to have benefits.

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Coconut oil is awesome for your health, but if you want personalized care with your health, schedule a free call here and we will help: http://www.prism.miami

Prism Health The solution is out there. We can help you find it. prism.miami

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Thank you for reading through this, long live coconut oil. Pls RT if you enjoyed and be sure to check out all of our content + product recommendations over at http://www.analyzeandoptimize.io

Analyze & Optimize | enhanced existence Restoring youth through bioenergetics. Esoteric health information from Analyze & Optimize. analyzeandoptimize.io

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Posted - July 1, 2025 at 1:00 PM

Saved - July 26, 2025 at 8:23 AM

reSee.it AI Summary

A doctor identified hypothyroidism as the root cause of various health issues, diagnosing patients based on signs and symptoms rather than tests. Common symptoms include weakness, dry skin, lethargy, edema, feeling cold, thick tongue, coarse hair, impaired memory, constipation, and weight gain. He treated these conditions with natural desiccated thyroid. Additionally, he suggested dietary and lifestyle changes to improve thyroid function. Personalized health assistance is offered for those seeking help with these issues.

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Decades ago, a doctor cured THOUSANDS from conditions they were told were unknown & incurable. The root cause? Hypothyroidism. No bloodwork. No scans. His diagnosis instead was based off of signs + symptoms. Here are the 10 most common ones he documented (& how he solved it):

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1. Weakness - in 98-99% of people with low thyroid. Thyroid hormones have important actions on muscle cells: ➞ Increase energy production ➞ Promote differentiation into mature muscle fibers ➞ Stimulates type II muscle fibers ➞ Multiplies mitochondria Without them, your muscles suffer, and you feel weakness.

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2. Dry / coarse skin - in 79-97% of people with low thyroid. Thyroid hormones (mainly T3) stimulate epidermal proliferation. With hypothyroidism, skin cells renew more slowly, leading to: ➜ Accumulation of dead skin cells ➜ Thickened stratum corneum (outer skin layer) Giving a rough, flaky, dull appearance.

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3. Lethargy - in 85-91% of people with low thyroid. The primary function of thyroid is to increase how much energy you produce. It goes into your mitochondria and helps them pump out more ATP in the oxidative phosphorylation process. Without enough, you'll feel low energy.

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4. Edema / swelling - 86-90% Low thyroid function can: ◈ Increase capillary permeability ➞ fluid leaks into tissues ◈ Reduce lymph drainage ➞ lymph swells up The puffy face is common in hypothyroidism.

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5. Being cold - in 89-95% of people with low thyroid. One of thyroid hormones' primary roles is to increase heat generation in the mitochondria of your cells. Dr. Barnes would routinely diagnose people with hypothyroidism on morning temperature alone. If for multiple mornings, the underarm temperature was <97.8 °F (36.6 °C) - the person would likely benefit from thyroid therapy

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6. Thick tongue - in 60-82% of people with low thyroid. Low thyroid hormone levels lead to reduced degradation of glycosaminoglycans (GAGs). These GAGs accumulate in interstitial tissues - including the tongue. These molecules attract water → non-pitting edema → tissue thickening.

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7. Coarse hair - in 75-76% of people with low thyroid. ↓ Thyroid hormone → ↓ metabolic rate in follicle cells ↓ Keratin production → weaker hair ↓ sebaceous gland activity → less oil → hair becomes dry and brittle Altered hair cycle → more hairs prematurely shift to telogen (resting phase). Hair loss is also common.

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8. Impaired memory - in 65-66% of people with low thyroid. The brain is the most energy intensive organ in the body. It requires it for producing neurotransmitters and forming strong synapses. Without enough thyroid hormone, the entire energy system ceases. Brain fog is one of the most common symptoms of hypothyroidism.

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9. Constipation - in 54-61% of people with low thyroid. Thyroid hormones regulate the activity of the nervous system, which extends into the gut and controls motility. If you're low on thyroid, this leaves you susceptible to: ➜ SIBO ➜ IBS ➜ Constipation ➜ Candida & more.

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10. Weight gain - in 59-76% of people with low thyroid. Dr. Barnes documented countless cases of people losing stubborn weight with thyroid therapy. Low thyroid function is the number 1 cause of a sluggish metabolism, and thus can cause you to put on weight easily.

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Now, how did he solve these issues? Dr. Barnes routinely used natural desiccated thyroid to solve these issues, which I've written about below on how to dose and use properly.

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The ultimate supplement to boost your metabolism: THYROID HORMONE - A complete guide 1. Symptoms you may be hypothyroid Just to name a few: • ALWAYS being tired • Feeling COLD, especially at the extremities • Slow / lethargic speech • Stubborn weight gain • Poor mood • Puffy features: cheeks, love handles, general water retention • Gynecomastia (man boobs) • Muscular weakness • Dry skin and hair • Anxiety • Hair loss • Always being sick Digestion is particularly responsive to thyroid hormone. • Constipation or diarrhea • Nausea • Bacterial overgrowth • Reflux are all common in hypothyroidism. Thyroid hormone is: ⬨ Key for gut regeneration, healing ⬨ Pro-motility ⬨ Vital for producing digestive enzymes ⬨ Required for producing stomach acid ⬨ Critical for gut immunity, gut barrier 2. Why labs are often misleading TSH is the primary (and often only) metric a doctor will test for hypothyroidism. A lower TSH should be indicative of higher thyroid hormone secretion, but it doesn't tell the full story. For starters, TSH can be lowered by: • Infection • Trauma • Cortisol • Adrenaline • Caffeine • Fever So a low TSH alone cannot rule out hypothyroidism. The standard TSH reference range is also WAY too lenient (up to 5). TSH >2 has been associated with: • Heart disease • High cortisol Thyroid hormones: • T4 (inactive) • T3 (active, pro-metabolic) • Reverse T3 (anti-metabolic) can also be measured in the blood, but this doesn't tell the full story either. These hormones must be transported through the blood, enter their target cells, and attach to the specific proteins in the cells that facilitate their actions. Not as simple as thyroid in blood = thyroid activity. Values of the “free” T3 and T4 can be misleading as well. Thyroid hormones do not need to be "free" to exert their effects on various tissues, contrary the current medical dogma. I still think testing can often be helpful, but you can certainly be hypothyroid while your labs look good on paper. 3. Diagnostics An underarm temperature measured first thing in the morning, leaving the thermometer under the arm for 10 minutes to equilibrate, should start be >97.8°F. Lower temperatures are highly indicative of hypothyroidism. This was the gold standard thyroid test (along with aforementioned symptoms) that was successfully used to treat thousands of hypothyroid people before blood tests. You can have “ideal” thyroid lab values yet be at the temperature of a hibernating bear. A healthy resting pulse averaged 85 beats per minute, though Dr. Ward Dean has suggested between 65-75 is a good range. If you eat carbs can and feel more tired and have lower temperature and pulse rate, this indicates a reliance on the stress hormones and a lack of thyroid function. The response of the Achilles tendon when tapped was another assessment tool. In a well-functioning thyroid, the foot would swing back energetically due to quick muscle relaxation. but a slow, controlled return motion indicated potentially sluggish energy status, often a sign of hypothyroidism. High cholesterol is another sign of hypothyroidism, while thyroid supplementation normalizes it. 4. NOT supplementing thyroid is unnatural Consuming thyroid gland is as natural and "ancestral" as it gets. Paleo researchers have stated that we probably consumed lots of thyroid gland throughout human history: "the shift from scavenging towards hunting... would have increased thyroid gland consumption by hominins and thereby exogenous thyroid exposure." "these Homo forebears started consuming small animals, such as amphibians, birds, and reptiles. This prey was consumed whole, and the animals’ thyroid glands thus provided a significant amount of thyroid hormone to their hominid predators." "Nevertheless, tissues and organs (including thyroid glands) are commonly consumed by the primary hunters" In fact, thyroid gland used to be in common foods like ground beef up until the mid 80s. It is only recently when we stopped eating the whole animal, including the thyroid gland! 5. Using natural desiccated thyroid (NDT) Desiccated thyroid comes from the thyroid glands of pigs or cows, and is the traditional way of supplanting thyroid hormones. A grain (60 mg) is the unit of measurement for supplementation, containing ~40 mcg T4 + ~10 mcg T3. A starting dose of a half grain is reasonable, and should be continued for 2-4 weeks before adjusting. The hormones take around this long to stabilize. As you use NDT, you should consistently track: 1. Morning temperature 2. Symptoms Once you get to >97.8°F and symptoms resolve, the correct dose has been found. The brand matters a lot. Many products seem to be unreliable, or outright useless. That’s definitely been my experience. I’ve tried numerous products over the last few years. I'll link below the thyroid product I have been using recently for myself and with clients. I would take it with food to slow the absorption, or even split into multiple doses with meals. I prefer at dinner. While some may require full replacement (4 to 5 grains), others find relief with as little as 15 mg (quarter grain). Broda Barnes observed that his patients often required about two grains of thyroid to alleviate hypothyroid symptoms, occasionally needing more. If you experience • Too fast of a heart rate • Palpitations, • Anxiety, • Overheating • Fatigue • Shaky feelings then you might have taken too much thyroid. The amount taken should be reduced or discontinued entirely. Effects of over stimulation should resolve in a few hours. This type of response can also indicate low cholesterol or an issue with liver function, two systems that the thyroid depends on to do its good. You may also need more nutrients, as the increased metabolic rate demands more resources. Eat your liver, egg yolks, and oysters. Many people who should be candidates for supplementation find that thyroid does nothing for them, no matter how much they take. In my experience, this always seems to be tied to an issue with the gut. I would try to address this first. Or, you just may not need it at all. You may need to address other factors. Of course, supplementing thyroid is not the ONLY way to improve thyroid function, but it seems like an appropriate strategy when other factors have been addressed.

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The product we typically use is this one https://lifegivingstore.com/grass-fed-beef-thyroid-natural-desiccated-thyroid-ndt/ref/10964/

Beef Thyroid Supplement | Natural Dessicated Thyroid for Optimal Health Support metabolic health, mood, and energy with beef thyroid supplement. Sourced from 100% grass-fed NZ cows, GMO-free, non-defatted, and nutrient-rich. Includes a scoop for easy use! lifegivingstore.com

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You also don't need to directly jump into desiccated thyroid off the bat. There are a number of other dietary + lifestyle factors that can help you up your thyroid function, which I've covered here:

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The key to unlocking your metabolism, mood, energy and gut health is sitting under your tongue being ignored by your doctor. This is the ULTIMATE AND COMPLETE GUIDE TO THYROID HEALTH so you can optimize it:

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Solving thyroid issues, or any other health problems, can be difficult on your own, but we can help. If YOU want personalized help from us with your health, click where it says “schedule a free call” here: http://prism.miami

Prism Health The solution is out there. We can help you find it. prism.miami

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Thank you for reading through this. Give this tweet below a repost if you found it interesting to spread the message. https://t.co/xN3QTQXltz

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Decades ago, a doctor cured THOUSANDS from conditions they were told were unknown & incurable. The root cause? Hypothyroidism. No bloodwork. No scans. His diagnosis instead was based off of signs + symptoms. Here are the 10 most common ones he documented (& how he solved it):

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Posted - January 1, 2025 at 6:07 PM

Saved - July 3, 2025 at 7:14 AM

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The dessert that protects against diabetes, cavities, inflammation and even cancer. You won't believe the incredible benefits of RAW HONEY:

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Posted - March 18, 2025 at 3:05 PM

Saved - June 29, 2025 at 9:35 AM

reSee.it AI Summary

I’ve been exploring how high-carb diets can aid in weight loss and improve insulin resistance. Studies show that people can eat as many carbs as they want while losing weight, often without calorie restriction. Diets with 58% to 70% carbs have led to significant fat loss and improved health markers, even reversing diabetes symptoms. The key seems to be keeping fat intake low, as high-fat diets often lead to overeating. Overall, a high-carb, low-fat approach appears beneficial for long-term health and weight management.

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You can eat AS MANY CARBS as you want, while LOSING weight and REVERSING insulin resistance. Scientists have been studying it for decades. Here’s the proof, and why an ULTRA HIGH CARB DIET can actually help you AVOID obesity and diabetes:

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A high carb diet causes fat loss, without reducing calories. In this study, people cut their fat calories from 38%➜28%, and increased their carb intake accordingly. They were told they could eat as much as they wanted. Their weight dropped like a rock.

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Eat as much as you want & lose weight. 3 diets, people could eat as much as they want: 1. 58% calories from carbs, 12% protein, 30% fat 2. 45% carbs, 25% protein, 30% fat 3. A 40% fat diet Diets 1 & 2 substantially reduced belly fat. Diet 3 gained weight.

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A high carb / low fat diet drops belly fat, without reducing calories. Another study here showed that an ~18% fat diet resulted in greater fat loss than a ~35% fat one. Same calories.

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A 70% carb diet helps in weight loss - without restricting calories. They actually told people to eat more to maintain their weight for the sake of the research, but they kept losing weight. It also improved their insulin resistance.

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Eating as much as you want on a high carb/low fat diet causes weight loss, and tastes just as good. Yep. Here they restricted fat intake to 20-25% of calories. Not only did they drop weight, but there was NO reported difference in how palatable the diets were.

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A 65% carb diet causes weight loss, need to force feed people to maintain weight. 15% fat in the diet here. People needed to force feed an extra ~300-400 calories just to NOT lose weight. Crazy.

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Yeah you might lose weight, but your blood sugar and insulin will be through the roof, right? Nope. In fact, people reversed the signs of diabetes on the "rice diet," which was 95% carb, or about a pound of carbs daily).

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Ultra high carb, very low fat diets can cure chronic diseases. The "rice diet" in the 1940s consisted mainly of rice and fruit / fruit juice, showing success in reversing: ◇ Diabetes ◇ High blood pressure ◇ Heart disease even without weight loss. Ultra high carb, very low fat diet once cured chronic diseases.

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High carb diets used to be the standard treatment for diabetes. For example, in this study they used an 85% carb diet and saw: ◇ Lower insulin ◇ Lower blood sugar ◇ Improved insulin sensitivity No restriction.

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An even crazier set of experiments showed that 80% SUGAR diets could dramatically improve insulin resistance. Yep, 80% glucose or sucrose (table sugar) had this effect. The 80% sugar diets outperformed diets that were 60, 40 and 20% sugar.

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INCREASED CARBOHYDRATE TOLERANCE IN DIABETICS FOLLOWING THE HOURLY ADMINISTRATION OF GLUCOSE AND INSULIN OVER LONG PERIODS. Yeah, that's the title of this paper. Do I need to elaborate more?

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The key is the LOW FAT. While most of us think of junk food as being high carb, it's equally (and often higher) high fat. ◈ Chips ◈ Donuts ◈ Fried foods ◈ Cheeseburgers ◈ Pizza etc etc These foods have tons of FAT, especially if you eat out. They're often drenched in oil or have tons of butter or cheese added, or have sauces / dressings that are mostly fat. Dairy fat, coconut oil, olive oil are what I consider to be healthy fats, but even those can be overconsumed. The cutoff seems to be at around 30% of calories from fat, which really isn't difficult to hit if you make your own foods. Lower than that is often better. Fat is important to making food taste good, but we certainly don't need the amounts we eat. Commercial food just way overdoes it. The average American eats right around 35% fat, in conjunction with high carbs. That is THE fattening diet. High carb + high fat. In fact, that's what we use to fatten up animals: a high carb, high fat (seed oil) diet.

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More on leptin here:

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The reason you can’t lose weight (or keep it off) no matter how hard you try. LEPTIN: why it’s SO important and how to optimize yours to boost your metabolism and finally stay thin for life.

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Obviously, you can lose weight and maintain it on a low carb / high fat diet. However, the inverse is also true, and in my view is preferable for health in the long run. More on why below:

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Keto, Carnivore and Fasting are DECIMATING your metabolism. The thyroid needs carbs. Here’s why:

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Losing weight can certainly be tough, but it's important to do so in a sustainable and healthy way. If you want some personalized help from us with that, or any of your other health goals, click here where it says "schedule free consultation" http://www.prism.miami

Prism Health The solution is out there. We can help you find it. prism.miami

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Thank you for reading through this. Give this tweet below a repost if you found it interesting to spread the message.

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You can eat AS MANY CARBS as you want, while LOSING weight and REVERSING insulin resistance. Scientists have been studying it for decades. Here’s the proof, and why an ULTRA HIGH CARB DIET can actually help you AVOID obesity and diabetes:

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The role of low-fat diets in body weight control: a meta-analysis of ad libitum dietary intervention studies - International Journal of Obesity OBJECTIVES: Low-fat high-carbohydrate diets are recommended to prevent weight gain in normal weight subjects and reduce body weight in overweight and obese. However, their efficacy is controversial. We evaluated the efficacy of ad libitum low-fat diets in reducing body weight in non-diabetic individuals from the results of intervention trials. DESIGN: Studies were identified from a computerized search of the Medline database from January 1966 to July 1999 and other sources. Inclusion criteria were: controlled trials lasting more than 2 months comparing ad libitum low-fat diets as the sole intervention with a control group consuming habitual diet or a medium-fat diet ad libitum. MAIN OUTCOME MEASURES: Differences in changes in dietary fat intake, energy intake and body weight. Weighted mean differences for continuous data and 95% confidence intervals (CIs) were calculated. RESULTS: Two authors independently selected the studies meeting the inclusion criteria and extracted data from 16 trials (duration of 2–12 months) with 19 intervention groups, enrolling 1910 individuals. Fourteen were randomized. Weight loss was not the primary aim in 11 studies. Before the interventions the mean proportions of dietary energy from fat in the studies were 37.7% (95% CI, 36.9–38.5) in the low-fat groups, and 37.4% (36.4–38.4) in the control groups. The low-fat intervention produced a mean fat reduction of 10.2% (8.1–12.3). Low-fat intervention groups showed a greater weight loss than control groups (3.2 kg, 95% confidence interval 1.9–4.5 kg; P<0.0001), and a greater reduction in energy intake (1138 kJ/day, 95% confidence interval 564–1712 kJ/day, P=0.002). Having a body weight 10 kg higher than the average pre-treatment body weight was associated with a 2.6±0.8 kg (P=0.011) greater difference in weight loss. CONCLUSION: A reduction in dietary fat without intentional restriction of energy intake causes weight loss, which is more substantial in heavier subjects. nature.com

Randomized trial on protein vs carbohydrate in ad libitum fat reduced diet for the treatment of obesity - International Journal of Obesity OBJECTIVE: To study the effect on weight loss in obese subjects by replacement of carbohydrate by protein in ad libitum consumed fat-reduced diets. DESIGN: Randomized dietary intervention study over six months comparing two ad libitum fat reduced diets (30% of total energy) strictly controlled in composition: High-carbohydrate (HC, protein 12% of total energy) or high-protein (HP, protein 25% of total energy). SETTING AND PARTICIPANTS: Subjects were 65 healthy, overweight and obese subjects (50 women, 15 men, aged 18–55 y) randomly assigned to HC (n=25), HP (n=25) or a control group (C, n=15). All food was provided by self-selection in a shop at the department, and compliance to the diet composition was evaluated by urinary nitrogen excretion. MAIN OUTCOME MEASURE: Change in body weight, body composition and blood lipids. RESULTS: More than 90% completed the trial. Weight loss after six months was 5.1 kg in the HC group and 8.9 kg in the HP group (difference 3.7 kg, 95% confidence interval (CI)(1.3–6.2 kg) P<0.001), and fat loss was 4.3 kg and 7.6 kg, respectively (difference 3.3 kg (1.1–5.5 kg) P<0.0001), whereas no changes occurred in the control group. More subjects lost >10 kg in the HP group (35 %) than in the HC group (9 %). The HP diet only decreased fasting plasma triglycerides and free fatty acids significantly. CONCLUSIONS: Replacement of some dietary carbohydrate by protein in an ad libitum fat-reduced diet, improves weight loss and increases the proportion of subjects achieving a clinically relevant weight loss. More freedom to choose between protein-rich and complex carbohydrate-rich foods may allow obese subjects to choose more lean meat and dairy products, and hence improve adherence to low-fat diets in weight reduction programs. nature.com

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INCREASED CARBOHYDRATE TOLERANCE IN DIABETICS FOLLOWING THE HOURLY ADMINISTRATION OF GLUCOSE AND INSULIN OVER LONG PERIODS Yeah, that's the title. "A number of severe cases of diabetes have been given glucose and insulin hourly without other food over periods of days. Given

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If carbs make you fat, why do higher carb, lower fat diets prevent obesity, and obese people eat more fat and less carbs than thin people? https://t.co/0OnSM7R0IU

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Carbs increase leptin. This is because insulin directly promotes leptin secretion. Thus, the more you fast and avoid carbs, the less leptin secretion you'll get.

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Posted - December 27, 2023 at 5:00 PM

Saved - June 29, 2025 at 8:17 AM

reSee.it AI Summary

I've been exploring the impact of hypothyroidism on various health issues, even when maintaining a healthy lifestyle. Symptoms like fatigue, weight retention, and mood changes can stem from thyroid dysfunction. I shared insights from Dr. Broda Barnes, highlighting how thyroid hormone affects everything from energy levels to mental clarity. If you're experiencing unexplained symptoms, it might be worth considering thyroid health. I'm using a natural desiccated thyroid product and am open to discussing ways to optimize thyroid function.

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Unexplained health problems? Even if you eat healthy and exercise regularly? Like something is off, but you can’t put your finger on it? This could be the solution you’ve been looking for. 20 seemingly unrelated symptoms that could result from HYPOTHYROIDISM (and what to do about it)

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Thanks to the late, great, Dr. Broda Barnes. A man who helped countless people who were hopelessly sick, a mystery to standard medicine, and desperate for life. With nothing more than a thermometer and some desiccated thyroid. Here are some of the most shocking transformations he described🔽

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MAN BOOBS: a consequence of low thyroid function?!

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Think about thyroid before TRT if you have low T!

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Never sweating even when warm or exercising? Could be from hypothyroidism

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Are you ALWAYS tired, lethargic, no matter how much sleep you get or how much you rest? Hypothyroidism could be the cause…

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Have difficulty speaking swiftly and fluently? Words on the tip of your tongue but can’t get it? You may just be hypothyroid. It tends to slow down all of your physical and mental functions.

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Puffy love handles, chubby cheeks, or generally just feel like you retain more water than you should? Could be a lack of thyroid hormone!

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If you feel muscular weakness, like you SHOULD be stronger or more mobile than you feel, it could be from hypothyroidism.

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If your skin is constantly dry, and your hair is coarse or very thick and rugged, thyroid might just be what you need.

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COLD. Are you always COLD, even in normal temperatures, especially at the extremities?

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Mouth breathers may just be hypothyroid. Enlargement of the tongue and poor dental development are common when thyroid is insufficient.

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Are you very forgetful? Is it difficult to maintain and integrate new information to you? (It’s the thyroid)

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Poor mood, apathy, and depression can all be caused by a lack of thyroid hormone.

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The thyroid exerts MAJOR control over the gut. Seemingly paradoxical, this can result in either constipation or diarrhea.

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If you have very stubborn weight issues, can’t lose weight even if you barely eat at all, hypothyroidism may be your issue. Here are some transformations on natural desiccated thyroid:

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This is the natural desiccated thyroid product I have been using, the best one I’ve tried over the last 2-3 years. [Will have more content on dosing / use over the next few days] https://lifegivingstore.com/grass-fed-beef-thyroid-natural-desiccated-thyroid-ndt/ref/10964/

Beef Thyroid Supplement | Natural Dessicated Thyroid for Optimal Health Support metabolic health, mood, and energy with beef thyroid supplement. Sourced from 100% grass-fed NZ cows, GMO-free, non-defatted, and nutrient-rich. Includes a scoop for easy use! lifegivingstore.com

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The mystery of hair loss may be solved by thyroid hormone.

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Respiratory parameters are much worse in hypothyroidism Frequent shortness of breath or trouble breathing is another common sign your thyroid is screaming for help.

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Trouble hearing? Thyroid may be the culprit!

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Broda Barnes noted that the susceptibility to getting sick very often was frequently driven by hypothyroidism.

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Chronic ANXIETY or fear can be driven by hypothyroidism

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A lack of thyroid hormone activity can drive any health problem you can think of because it is the body’s primary metabolic regulator. When you can’t produce enough energy, you lose your structure, you become stressed and ill. This is at the core of our poor health.

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Absolutely. Can stimulate appetite and have an anti-catabolic effect. Often times we think of metabolic dysfunction as getting fat, but equally as big a problem is the wasting away underweight phenotype

@noekel_ - noé

@Outdoctrination could hypothyroidism be possible even though I've been skinny all my life?

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If YOU want some help optimizing thyroid function, we are here to help. Schedule a free call by clicking "Schedule a free call" here http://prism.miami

Prism Health The solution is out there. We can help you find it. prism.miami

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Posted - December 26, 2023 at 7:33 PM

Saved - June 29, 2025 at 8:17 AM

reSee.it AI Summary

I reflect on the transformative power of desiccated thyroid therapy, inspired by Dr. Broda Barnes. His work has helped many, including a mother battling depression, a professor struggling with fatigue, and a teenager who turned to drugs. I've seen remarkable recoveries from conditions like eczema, migraines, and even hallucinations. Many individuals previously labeled as lazy or neurotic found relief and renewed energy. Personally, I've started using desiccated thyroid and am eager to share more about my experience and insights on dosing soon.

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Thanks to the late, great, Dr. Broda Barnes. A man who helped countless people who were hopelessly sick, a mystery to standard medicine, and desperate for life. With nothing more than a thermometer and some desiccated thyroid. Here are some of the most shocking transformations he described🔽 https://x.com/NStumphauzer/s/NStumphauzer/status/1739697355060867450

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Mother who has trouble caring for her children due to depression, fatigue, irregular menstruation, and constant infections, gets back on her feet with thyroid.

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Chair/professor needed to sleep for 10 hours per night… before thyroid therapy. "Like many hypothyroid patients I have seen, he told me that he felt as if he had been 'born tired... I am just tired now of being tired and of having to fight so hard against it.'"

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Laziness: a character flaw or a symptom of poor metabolism?

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Bleeding eczema covering virtually his whole body… Five months of thyroid therapy cleared his skin.

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Housewife with forgetfulness, constant shivering, and a fear of crowds, recommended by physicians to go to a mental institution. Within several months [of thyroid therapy], she was free of all symptoms, including her fears.

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Woman with brutal seasonal depression requiring hospitalization, glides through four winters on thyroid therapy

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Man goes from lethargic and overweight to upbeat and lean with desiccated thyroid. Only one problem: that made him want to leave his wife. Barnes makes the case that opposite [thyroid functions] do not attract, but that hypothyroid individuals tend to stick together.

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17 year old boy copes with fatigue by dropping out of school, starting to do drugs and commit crime… until desiccated thyroid.

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“he was withdrawn, had little to do with the family, refused to keep his room reasonably neat and orderly…. His response, too, on thyroid therapy was gratifying.”

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I got motivated to read more into this topic after starting to add back in desiccated thyroid over the last few weeks. Definitely a big add for me personally. This is the brand I use, best I've tried so far [will have more content on dosing / use soon] https://lifegivingstore.com/grass-fed-beef-thyroid-natural-desiccated-thyroid-ndt/ref/10964/

Beef Thyroid Supplement | Natural Dessicated Thyroid for Optimal Health Support metabolic health, mood, and energy with beef thyroid supplement. Sourced from 100% grass-fed NZ cows, GMO-free, non-defatted, and nutrient-rich. Includes a scoop for easy use! lifegivingstore.com

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A high performing and acclaimed doctor suffered from migraines and constant fatigue. His marriage started to suffer. Desiccated thyroid to the rescue once again!

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“Within thirty days after thyroid therapy was started, a marked decrease in both frequency and severity of migraine was the rule. Of the first 100 migraine patients so studied and treated, 95 benefitted”

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Very relatable… Students with mild hypothyroidism would be okay for most of the semester until exams hit, and the stress pushed them past their breaking point. Desiccated thyroid would help.

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Man with fatigue his whole life, could not hold a job due to it. Contemplated suicide at 25. Doctors were clueless. The red flag? 96 degree temperature. Desiccated thyroid given, cured.

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Persistent hallucinations cured by desiccated thyroid treatment

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People become highly anti-social when hypothyroid “Many preferred seclusion, wanting nothing to do with others” One man “had become suspicious that everyone was trying to poison him. He refused to eat”

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"untreated thyroid deficiency could easily be mis- taken for neurotics." "thyroid hormones have the ability to balance emotions and can aid in the treatment of mental disorders."

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Suicidal student saved by desiccated thyroid treatment.

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These excerpts are from his book Hypothyroidism: The Unsuspected Illness You can check that out here for free https://archive.org/details/hypothyroidismun00barn/mode/2up

Hypothyroidism : the unsuspected illness : Barnes, Broda O. (Broda Otto), 1906- : Free Download, Borrow, and Streaming : Internet Archive Includes bibliographical references (p. 287-297) archive.org

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If YOU want personalized help from us with your thyroid health, click where it says “schedule a free call” here: http://prism.miami

Prism Health The solution is out there. We can help you find it. prism.miami

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Posted - January 11, 2024 at 8:58 PM

Saved - June 29, 2025 at 7:40 AM

reSee.it AI Summary

Keto, carnivore diets, and fasting can harm metabolism by negatively impacting thyroid function, which is essential for metabolic health. Many health issues stem from undiagnosed hypothyroidism, yet doctors often overlook comprehensive thyroid testing. Low carb diets can lower T3 levels, leading to increased LDL cholesterol and metabolic issues. Fasting further suppresses thyroid hormones and can result in a sluggish metabolism. I've experienced the coldness associated with these diets firsthand. For those needing guidance, my team offers consulting to optimize thyroid health.

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Keto, Carnivore and Fasting are DECIMATING your metabolism. The thyroid needs carbs. Here’s why:

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The thyroid, is the master gland of our metabolism, and our metabolic mastery is what drives our health. The thyroid plays frequently neglected role in a myriad of health issues, if you don't believe me see here:

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Unexplained health problems? Even if you eat healthy and exercise regularly? Like something is off, but you can’t put your finger on it? This could be the solution you’ve been looking for. 20 seemingly unrelated symptoms that could result from HYPOTHYROIDISM (and what to do about it)

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Unfortunately, it's quite common for patients displaying obvious signs of health problems to encounter doctors who readily admit they are stumped, without ever evaluating thyroid function. And when they do get around to testing, they often only measure Thyroid Stimulating Hormone (TSH). Here's the crucial piece they miss: TSH alone is far from the full picture.

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TSH is a precursor produced by the pituitary gland that must be converted by the thyroid into T4, which itself isn't the active thyroid hormone that the body ultimately utilizes. T4 can be converted by peripheral tissues into reverse T3, which is anti-metabolic, or into T3, the active thyroid hormone that is truly essential for our metabolic health. Understanding this distinction is vital.

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Why is this important, especially in the context of low carb diets? Well, even though TSH levels may be maintained on a low carb regimen, people following such diets typically show decreases in T3 levels, the metabolically active thyroid hormone.

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It's repeatedly observed that individuals on low carb diets tend to experience elevated levels of LDL cholesterol, one of the reasons for which might be connected to lower T3 levels, since T3 is critical in the creation of LDL receptors, which pull the cholesterol out of the blood into the liver. Thyroid hormone is also crucial for converting the cholesterol into downstream steroid hormones.

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The relationship between thyroid hormone levels and LDL cholesterol is striking, as desiccated thyroid therapy reliably lowers cholesterol.

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Check out this thread for more on implementing desiccated thyroid:

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How many of these symptoms do you have? Chances are, at least a few. Fortunately, there is a solution. Let’s talk about how to sensibly and safely supplement THYROID to reclaim your energy and vitality.

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Unexplained health problems? Even if you eat healthy and exercise regularly? Like something is off, but you can’t put your finger on it? This could be the solution you’ve been looking for. 20 seemingly unrelated symptoms that could result from HYPOTHYROIDISM (and what to do

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On a low carb diet, there is a decrease in insulin, corresponding with an increase in the functioning of stress hormones such as adrenaline, noradrenaline, and cortisol. These hormones are known to decrease the conversion of T4 into T3 and increase the conversion into reverse T3. Cortisol in particular can suppress the output of TSH. Meanwhile, insulin is known to increase the output of T4 from the thyroid and the conversion of T4 into T3.

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Fasting is known to tank T3 status, and increase reverse T3 to suppress the metabolic rate. Carbohydrate feeding differentially improves the thyroid profile, which is not replicated by protein and fat.

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Interestingly, elevated levels of noradrenaline are also found in patients with hypothyroidism. Ultimately, with reduced levels of T3 due to a low carb diet, the body is likely compensating by increasing the levels of these stress hormones as a mechanism to maintain energy and metabolic function.

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Low carb or fasting proponents may suggest that because low carb diets have been shown to improve insulin and leptin sensitivity, the same positive effect might be assumed for thyroid hormones, that you need less thyroid hormone and become more “thyroid sensitive,” and therefore lower T3 is okay. Unfortunately, nothing could be further from the truth. Here's why:

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With a lack of carbohydrates and insulin in the picture, fat gets released from the adipose tissue and free fatty acid levels rise systemically. These free fatty acids are known to not only prevent the transport of thyroid hormones, but also to block their actions in the cell, something that won’t get picked up on any blood test.

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Free fatty acids also act directly at the thyroid level to suppress the production of important thyroid components, such as thyroglobulin, thyroperoxidase and the iodine transporter.

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Fasting causes serum T3, T4 and TSH to decrease, along with lower conversion of T4 into T3. The effects on serum TH concentrations become more pronounced with longer fasting periods.

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Thyroid hormone conversion is largely regulated in the liver, driven by enzymes known as deiodinases, which facilitate the interconversion of thyroid hormones. Deiodinase 3, the primary enzyme in deactivating thyroid hormones (T4 into reverse T3 or T2), is known to be induced in response to liver injury, inflammation... or fasting.

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Additionally, the liver influences thyroid hormone concentrations in the bloodstream by producing binding proteins that lower thyroid hormone bioavailability. For instance, the proportion of one of these proteins, thyroid binding globulin, increases in fasting, contributing to a less bioavailable form of the hormone to other tissues.

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However, thyroid hormones can also be inactivated and excreted through the feces or urine, through the processes of sulfation and glucuronidation, which are ubiquitous in detoxification. Enzymes responsible for sulfation and glucuronidation of thyroid hormone are increased by fasting. In other words, by chronically fasting, you are literally pissing away your metabolism.

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Ketogenic diets and fasting are also liable to decrease the body temperature, a well known outcome of inadequate thyroid function.

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All in all, it seems very clear that the thyroid thrives on carbohydrate and becomes sluggish in times of fasting. Given how important thyroid function is for nearly every bodily function, it's definitely something to be aware of if you choose to undertake such a lifestyle. Personally, I can attest to the fact that chronic fasting and carb restriction made me unnaturally cold seemingly all the time.

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If you want some help in adjusting your diet, solving any gut issues, or just optimizing your thyroid and metabolism, we've just launched our premium consulting platform, PRISM, where our team can help you. Schedule a free consult here to hear more! https://www.prism.miami/get-started

Prism Health prism.miami

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Thank you for reading along. I hope you learned something and can use this info to improve your health. Be sure to check out all of our content and supplements, as well as ways to donate, over at https://lnk.bio/analyze.and.optimize

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Posted - September 7, 2024 at 5:28 PM

Saved - June 28, 2025 at 3:05 AM

reSee.it AI Summary

Zinc is a powerhouse nutrient with extensive benefits for gut health, metabolism, skin, hair, and sexual health. It rapidly repairs the gut, prevents leaky gut, and reduces inflammation, making it essential for digestive health. Zinc also boosts metabolism, enhances energy production, and lowers cortisol and anxiety levels. It's crucial for skin regeneration and hair growth, while also improving mood and sleep quality. With a significant portion of the population deficient, it's vital to consider dietary sources like oysters and red meat, or supplementation for optimal health.

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It heals the gut & skin, reduces inflammation & fatigue, and massively boosts sexual health. That's just scratching the surface. The benefits of ZINC are nearly endless:

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Zinc rapidly repairs the gut. The gut can be broken down by bacterial toxins (LPS) or high doses of antibiotics, but zinc gluconate: • Alleviates digestive symptoms • Prevents "leaky gut" • Decreases pathogenic bacteria possibly the #1 nutrient for digestion.

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Zinc boosts metabolism. Zinc is necessary for thyroid hormone: • Production • Conversion • Signaling Periods of zinc deficiency (MP2 here) drastically lower metabolism.

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Zinc carnosine prevents "leaky gut." 37.5 mg, 2x daily, completely halted the permeability in the intestine. This permeability drives: • Various gut symptoms • Food intolerance • Systemic inflammation

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Zinc Carnosine powerfully reduces gut inflammation. People with ulcerative colitis (inflammatory bowel disease) taking it: ‣ Dramatically reduced disease progression ‣ Reduced digestive symptoms by nearly 40% Antibacterial, anti-inflammatory, repairs gut lining.

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Zinc is the ultimate nutrient for SKIN. Zinc has shown promise for: ⬩Warts ⬩Acne ⬩Rosacea ⬩Vitiligo ⬩Psoriasis ⬩Eczema ⬩Sunburn ⬩Wrinkles ⬩Dandruff It supports nearly every process in regenerating new skin.

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Zinc is a critical factor in hair loss. Zinc: • Levels very low in alopecia • A vital cofactor for growth and differentiation of keratinocytes (hair producing cells) • Oral / topical supplementation can have benefit for growth

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Zinc reverses fatigue. Zinc at just 30 mg per day reduced fatigue by ~20% within 3 months. Zinc: ‣ Enhances mitochondrial energy production ‣ Has anti-inflammatory function ‣ Required in hormonal signaling + production and levels declines in aging.

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Zinc low, copper high in chronic fatigue / pain. Excess copper can: • Increase estrogen • Drive inflammation • Cause oxidative stress contributing to fibromyalgia - zinc opposes these functions.

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Zinc is an anti-aging nutrient. The Copper / Zinc ratio is elevated in: ‣ Age ‣ Cancer ‣ Inflammation ‣ Insulin resistance ‣ Autism Zinc levels decline as we age, less zinc relative to copper predicts death.

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Zinc reduces depression by half. Just 25 mg of zinc daily was shown to have this effect. Zinc: ⬩Lowers glutamate ⬩Reduce intracellular calcium ⬩Antagonizes the NMDA system ⬩Increases BDNF In the brain, all vital for neurological function.

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Zinc dramatically lowers cortisol. A 50 mg zinc dose suppressed the stress hormone by around 70% here. While the HPA axis, which produces cortisol, depletes zinc, adding it back in markedly lowers this stress system.

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Zinc levels are low in anxiety. Stress, the principle driver of anxiety, is one factor that depletes zinc status. Supplementation has shown benefits as well.

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Zinc for a good night's sleep. Consuming 40g oysters (B): ‣ Increased sleep efficiency ‣ Decreased time to fall asleep Compared to eating low zinc scallops. Zinc's potent anti-stress effects on display once again.

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Zinc is a Godsend for male sexual health. Low T men given zinc for under 2 months: ‣ More than DOUBLED sperm count ‣ Increased testosterone by over 50% ‣ Increased DHT by over 30% 9/22 men got their wives pregnant, when none could for 5 years prior.

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Zinc lowers estrogen. Excess estrogen is a serious issue, even for women. Production of estrogen from androgens increases in: ‣ Aging ‣ Inflammation ‣ Fat accumulation Zinc deficiency compounds this, further increasing the conversion of androgens to estrogens.

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Zinc supercharges libido, sexual performance. Zinc: ‣ Raises testosterone / Free T / DHT ‣ Enhances libido (in men & women) ‣ Improves erectile function ‣ Enhances sperm quality, abundance ‣ Involved in ALL steroid hormone signaling no mineral more important for this.

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Zinc shortens common cold duration by 30-40%. Zinc lozenges have been repeatedly shown to be effective for dealing with this, by: ✪ Reducing inflammation ✪ Stopping viral replication ✪ Having direct antimicrobial effects

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Zinc + Vitamin C powerfully reduce heavy metals. ‣ Both prevent absorption of lead, cadmium, etc ‣ Zinc directly promotes their excretion by producing metallothionein ‣ Both critical for antioxidant protection against them Some of our best protection.

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Zinc deficiency is a HUGE problem. Around 17% of people globally are deficient. Plus, our bodies lose it during: • Stress • Aging • Inflammation • Higher fiber intakes • Exercise yet we are SO dependent on it for nearly every function.

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The best food sources of zinc BY FAR are oysters and red meat. You need more of these foods than you think just to meet the RDA (~10 mg). A huge problem is that phytates in grains impede our absorption of it, so even with sufficient quantities, it can be tough to get enough.

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Which of course brings up the topic of supplementation. Zinc: • Gluconate • Acetate • Sulfate • Citrate can all work. We typically use gluconate. Zinc Carnosine is the most well studied for zinc's benefits on the gut, but can still increase zinc systemically. Other forms don't seem to be as good. I think going up to 30-50 mg of elemental zinc daily is pretty reasonable. Many say you NEED to supplement copper alongside zinc, but unless you're going to high doses I don't think that's true. We typically get plenty of copper in the diet, and the zinc / copper ratio declines with aging, disease, stress etc. Copper & iron are much more reactive and potentially harmful than zinc, and: - Estrogen increases iron & copper absorption - Excess copper can increase estrogen - Zinc prevents excess estrogenicity - Zinc protects against intracellular iron / copper toxicity - Zinc inhibits absorption of both - Copper + iron are in lots of foods, zinc is not

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If YOU would like some personalized help from us to achieve optimal health, give us a FREE CALL by clicking where it says “schedule a free call” here http://www.prism.miami

Prism Health The solution is out there. We can help you find it. prism.miami

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Posted - December 24, 2024 at 3:30 PM

Saved - June 28, 2025 at 2:59 AM

reSee.it AI Summary

I've shared a comprehensive protocol to prevent and treat sickness this winter. Key components include Vitamin C for immune support, zinc lozenges to alleviate cold symptoms, and methylene blue as an antiviral. Grounding, glycine, raw honey, aspirin, beef liver, and Vitamin D also play crucial roles in boosting immunity and recovery. Each element has unique benefits, from reducing inflammation to enhancing overall health. This protocol aims to optimize wellness and minimize illness during the colder months.

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READ THIS IF YOU DON'T WANT TO GET SICK THIS WINTER. Here is the ULTIMATE PROTOCOL for preventing + curing your sickness this winter (& why it works):

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1. VITAMIN C ◇ Improves immune clearance of pathogens ◇ Antioxidant protection ◇ Collagen production (forms physical barriers to infection) ◇ Vital for development of immune cell differentiation (gene regulation)

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Vitamin C powerfully protects against common cold. 1-3g per day, reduces: ◇ Sick days ◇ Symptom severity - headache, fever, chills, cough ◇ Frequency of colds Acerola cherry powder seems to be handled better in the gut than pure vitamin C.

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You can read more about the benefits and importance of vitamin C here:

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VITAMIN C: ⇨ Anti-cancer ⇨ Lowers stress ⇨ Renews skin ⇨ Improves sex life ⇨ Enhances energy & motivation ⇨ Crushes anxiety ⇨ Reduces sickness & more. Let's talk about the benefits of it, how to get enough and supplementation. THREAD:

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2. ZINC LOZENGES Sucking on zinc tablets, having them slowly dissolve, has strikingly beneficial effects for respiratory infections. ⇨ Direct antimicrobial ⇨ Immune cell differentiation ⇨ Improves pathogen clearance ⇨ Strengthens mucosal barriers

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Zinc lozenges cuts cold symptoms in half. ⇨ ~20 mg zinc lozenge ⇨ Every 2 hours ⇨ Up to 8X daily was shown to double the amount of people who recovered from common cold.

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Zinc lozenges nearly reverse all cold symptoms. ⇨ Cough ⇨ Drainage ⇨ Congestion ⇨ Sore throat & more. Same protocol: ⇨ ~20 mg zinc lozenge ⇨ Every 2 hours ⇨ Up to 8X daily these can be bought at most drug stores.

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I've written more about the broad protective benefits of zinc here:

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It heals the gut & skin, reduces inflammation & fatigue, and massively boosts sexual health. That's just scratching the surface. The benefits of ZINC are nearly endless:

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3. METHYLENE BLUE MB is a direct and potent antiviral. Especially if symptoms are mainly respiratory / throat, having 5-15 mg of methylene blue dissolved in water can quickly help lower the viral load. More on MB in the threads below:

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A literal blue dye somehow treats depression, Alzheimer's and even cancer. Here’s just some of the incredible things METHYLENE BLUE can do for your health:

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How a cheap clothing dye can turbocharge your energy production, bolster your mood and cognition, and prevent disease in the long run Let’s talk about METHYLENE BLUE. How it works [THREAD]

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This is the methylene blue product we use personally and with clients, ultra pure: https://healthnatura.com/simply-methylene-blue-400mcg-ready-to-use-solution-1oz/?ref=ANALYZEANDOPTIMIZE

Simply Methylene Blue 400mcg Ready to Use Solution 1oz healthnatura.com

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4. GROUNDING Surprisingly, grounding has actually been shown to improve recovery from COVID, likely due to its antioxidant / anti-inflammatory benefits. 20 minutes daily, minimum, bare feet on the grass. More on how grounding works below:

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The best thing you can do for your health that no one is talking about. You’ll be sleeping like a baby, reducing your stress, and crushing inflammation. Literally touch grass. Why GROUNDING is the missing link to your optimal health:

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Near complete resolution of inflammation within an hour of grounding. Literally just by putting your feet on the earth (grass or soil).

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If you live in the cold, you can use grounding sheets like this to get the benefits of grounding indoors and through the night: https://www.mitolife.co/products/grounding-technology?afmc=6hr&utm_campaign=6hr&utm_source=leaddyno&utm_medium=affiliate

GROUNDING TECHNOLOGY Fatigue, lethargy, insomnia, can all be signs that the body has built up a proton gradient that is affecting cellular function. Too much of a positive charge is never a good thing. To counteract this, the body needs to be able to neutralize or discharge this excess of protons. One way to do so, helping improve fatigue, mitolife.co

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5. GLYCINE Glycine mainly helps with immunity by aiding in the synthesis of collagen, which helps form our physical barriers to pathogens. Glycine also has a key anti-inflammatory and antioxidant roles.

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Glycine dramatically reduces risk of flu and cold. At 10g / day, >80% of people reported NO flu or cold. Prior to glycine, >80% DID get flu or colds. Insane.

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This is the glycine supplement we use personally and with clients: https://lifegivingstore.com/glycine-powder-usp-grade/ref/10964/

Glycine Powder USP Grade Glycine Powder USP Grade lifegivingstore.com

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Glycine is found mainly in tendons, broths, and skin of animals, and can also be supplemented. I would definitely include these foods for my illness diet. I've written more about that here:

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Better sleep, digestion, mental health. Even preventing cancer. The scraps you literally throw away are the healthiest thing you buy. Why GLYCINE / COLLAGEN are the key to unlocking the next level of your health:

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6. RAW HONEY Honey has tons of unique compounds that have: ◇ Antiviral ◇ Antibacterial ◇ Antifungal ◇ Antioxidant ◇ Anti-inflammatory properties.

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1 teaspoon of raw honey strikingly beneficial for cough. Selecting the darkest variety, just this little bit of raw honey consistently improves all metrics of infectious cough. You can have more though, no reason not to. More on honey below:

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Honey is literally one of the healthiest foods on the planet. Like with OJ, people think of it as "just sugar," but that's missing the massive quantities of unique compounds with medicinal benefits. Phenolics & flavonoids with: ☆ Antioxidant ☆ Anti-inflammatory ☆ Antibacterial ☆ Antifungal properties. Several studies have demonstrated that despite its high sugar content, raw honey can actually help to lower blood sugar, and even: ◇ Reduce inflammatory markers ◇ Shed fat ◇ Improve insulin sensitivity ◇ Diminish cancer growth ◇ Lower blood pressure in comparison with pure sugar. It also has beneficial effects for dental health. Again, distinguishing between pure sugar and raw honey is vital. While conventional wisdom claims sugar causes cavities, raw honey has literally been used as a toothpaste, as it: ◇ Reduces acidity ◇ Kills pathogenic bacteria in the mouth. These properties give it great value for the gut, too. It has both anti-pathogenic factors AND short carbohydrates that function as prebiotics for the "good" bacteria. The buzz about raw honey is real. Pun intended.

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Orange juice is literally one of the healthiest foods on the planet. It has proven antidepressant, anti-inflammatory, anti-diabetic and gut health promoting properties. Don’t believe me? Let’s get into it:

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7. ASPIRIN Not only does aspirin reduce inflammation, it encourages the resolution of inflammation - the way that illness actually ends. Other anti-inflammatories do not do the latter, so while they improve symptoms they don't help you get over the sickness. Aspirin does.

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Aspirin is a powerful antiviral. Shown capacity to eliminate flu, cold, and other respiratory viruses.

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Aspirin + caffeine rapidly reduces cold symptoms by ~70%. Adding caffeine to aspirin enhances the effect, resulting in relief of: ✧ Cough ✧ Pain ✧ Sore throat within hours.

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This is the aspirin we use personally and with clients, free of all of the common additives in most aspirin products. Starting with ~320 mg (4 scoops) is a good option. Can double that if need be. https://healthnatura.com/aspirin-powder-usp-60g/?ref=ANALYZEANDOPTIMIZE

Aspirin Powder USP 60g Discover our 99.5% pure aspirin powder USP 60g—free from fillers and additives. Order now for tested quality, precise dosing, and effective pain relief. healthnatura.com

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Aspirin has a ton of other beneficial effects, which I have written about here:

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Modern medicine’s greatest contribution to the health of mankind. It heals cancer, depression and is even a nootropic. And it’s safe and cheap to boot. Why ASPIRIN is so much more than a painkiller and a blood thinner:

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8. BEEF LIVER Liver is by far the best source of copper and vitamin A, both of which are vital for immunity. Copper: ◇ Direct antimicrobial (viruses, bacteria, fungi) ◇ Supports immune clearance ◇ Regulates iron balance ◇ Needed for immune cell production, differentiation

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VITAMIN A for immunity: Vitamin A works together with vitamins D and zinc to support: ◇ Immune cell differentiation ◇ Mucosal barrier function ◇ Antibody production Getting in 4-8 oz of beef liver a week would be good practice to get tons of copper and vitamin A.

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I've written extensively about the importance and benefits of vitamin A here:

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50% of people are deficient in this vitamin. It heals the gut, grows the brain, can boost testosterone and gives us glowing skin. These are the miraculous benefits of VITAMIN A, plus how to make sure you get enough. THREAD:

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9. VITAMIN D Lack of vitamin D might be the number 1 principle driver of seasonal illnesses. It: ☆ Supports immune cell differentiation ☆ Strengthens mucosal barriers ☆ Directly produces antimicrobial peptides.

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Vitamin D nearly completely prevents cold + flu. Even moderate doses (2,000 IU) have a very strong protective effect against these illnesses, even completely preventing them through the winter.

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This is the vitamin D supplement we use personally and with clients. For prevention, 5,000 IU can work well. If you're already sick, you can crank that way up - trying a 50,000 IU single dose and seeing how it goes. https://healthnatura.com/vitamin-d3-in-mct-oil-5000-i-u-1-ounce/?ref=ANALYZEANDOPTIMIZE

Vitamin D3 in MCT oil 5000 i.u. 1 ounce Discover pure, preservative-free Vitamin D3 in MCT oil. Each drop delivers 5000 i.u. for optimal health. Order now to boost your energy and wellness! healthnatura.com

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I've also written a ton about the benefits of vitamin D here:

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The FREE vitamin that NO ONE gets enough of. WAY beyond preventing colds, it enhances brain function, crushes stress and massively improves energy. Let's talk about the multifaceted benefits of VITAMIN D:

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IN SUMMARY, the cold / flu protocol: 1. 1-3g vitamin C (acerola cherry powder) 2. Zinc lozenges (every 2 hours) 3. 5-15 mg methylene blue 4. 20 mins minimum of grounding 5. 5-10 g of glycine 6. 1 or more tsp of raw, dark honey 7. 320-640 mg of aspirin (+ coffee) 8. 4-8 oz of beef liver weekly 9. 5,000-50,000 IU Vitamin D

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This protocol is awesome, but it might not be enough to optimize your health and immunity. If YOU want personalized help from us with your health, click where it says “schedule a free call” here: http://prism.miami

Prism Health The solution is out there. We can help you find it. prism.miami

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Thank you for reading through this, give this tweet a repost if you found it helpful to help spread the word and help us all: https://t.co/GgNx7YKMsT

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READ THIS IF YOU DON'T WANT TO GET SICK THIS WINTER. Here is the ULTIMATE PROTOCOL for preventing + curing your sickness this winter (& why it works):

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Posted - April 8, 2025 at 11:39 PM

Saved - June 27, 2025 at 2:47 PM

reSee.it AI Summary

Alzheimer's disease is projected to double in prevalence, yet current treatments fail to address its root causes. Key factors include brain atrophy, elevated cortisol, and impaired glucose metabolism, often likened to "Type 3 Diabetes." Solutions may involve lowering cortisol, enhancing glucose metabolism, and utilizing supplements like methylene blue, coconut oil, and creatine. Additionally, addressing inflammation, oxidative stress, and promoting brain cell growth through lifestyle changes and nutrients can support cognitive health. Understanding the role of genetics, particularly the APOE4 gene, is crucial, but lifestyle choices remain pivotal.

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Alzheimer's prevalence is set to double in the next 25 years. Yet, mainstream treatments have been complete and utter failures. Probably because they don't fundamentally understand the problem. Here's what really behind it, and what you might be able to do about it: https://t.co/Ku3Rd9xZQi

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Over 99% of Big Pharma's Alzheimer's drugs are useless. Why? - Because these drugs are missing the point. Solving cognitive decline means understanding and addressing every angle of the brain's health. Let's get into what that entails: https://t.co/lKc9o4vxwf

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The key finding in Alzheimer's is the ATOPHY of certain brain regions. Atrophy is the loss of functional tissue. We see loss of key brain regions - the hippocampus and the frontotemporal lobe. This is due to the death of the cells in these areas. https://t.co/CJoWh2OQCw

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Cortisol shrinks the brain. Cortisol is released during stress, and one of its primary roles is to break down tissue and turn it into energy to survive. Cortisol levels predict: ◇ Memory performance ◇ Brain volume loss https://t.co/yqNf02RMav

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Lowering cortisol grows back the brain. People with naturally elevated cortisol have lower brain volume in those same brain regions that are diminished in Alzheimer's. Fixing the cortisol reverses this. I put together a master guide on lowering cortisol below. https://t.co/PTs1kLE5Tz

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High cortisol, anxiety, and can’t sleep? This is for you. This is the ULTIMATE GUIDE to STRESS - the signs, the biological mechanisms and what to do about it:

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Another key finding in Alzheimer's is reduced GLUCOSE metabolism. Glucose is the brain's primary fuel source. Just like type 2 diabetes is poor glucose metabolism in the body, Alzheimer's has been called "Type 3 Diabetes" - it is poor glucose metabolism in the brain. https://t.co/LxuPVxIpFi

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Of course, mainstream dogma is also terrible at solving insulin resistance and fixing your glucose metabolism. I have also gone into a deep dive on what that entails below - from a systemic perspective. Things that help fix glucose metabolism also help Alzheimer's.

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Diabetes & insulin resistance plague nearly 90% of the Western world, because modern medicine doesn't understand, prevent or treat it properly. Let's talk about the TRUTH about INSULIN RESISTANCE - how it REALLY happens, and what to do about it:

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Methylene blue enhances cognitive function. It's shown to improve Alzheimer's disease by: ⬩Increasing blood flow to the brain ⬩Enhancing brain energy production ⬩Protecting against brain oxidative damage More on MB below. https://t.co/pOrs5ziWXx

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A literal blue dye somehow treats depression, Alzheimer's and even cancer. Here’s just some of the incredible things METHYLENE BLUE can do for your health:

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How a cheap clothing dye can turbocharge your energy production, bolster your mood and cognition, and prevent disease in the long run Let’s talk about METHYLENE BLUE. How it works [THREAD]

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Another example is red / infrared light therapy, which I covered in detail recently below. Red / infrared light works by stimulating mitochondrial enzymes to produce more energy. As we will see, all of the other biological phenomena seen in Alzheimer's are downstream of this.

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An incredibly powerful tool for mental & cognitive health. It heals depression, brain damage, Alzheimer's, and keeps your mind sharp. The benefits of RED / INFRARED LIGHT THERAPY for the brain are astonishing:

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Coconut oil reverses brain damage from Alzheimer's plaques. ◈ Prevents deterioration of brain cell structure ◈ Preserves synaptic vesicles for neurotransmission due to its MCTs - fats that support the brain's metabolism when glucose metabolism is impaired. https://t.co/0Ri9NIutk2

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Coconut oil improves Alzheimer's disease. 20 g/day showed improvements in >80% of patients over 6 weeks. More on the incredible benefits of coconut oil below. https://t.co/ddsWOnB8iC

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The anti-cancer, metabolism boosting and cognitive enhancing tool that's been hiding in your cabinet. COCONUT OIL is simply a marvel for your health, here's why:

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Creatine for Alzheimer's. Impaired creatine metabolism can drive protein accumulation + brain cell damage. Supplying creatine back combats this, protecting neurons and reducing protein accumulation. This is because creatine supports glucose metabolism. https://t.co/dGaL66tpOC

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Gym goers have been taking this forever. Little did they know the real gains came in their brain. For mental health and cognitive enhancement, here's why CREATINE might be your missing link:

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AMYLOID - the central player in Alzheimer's. Amyloid β plaques are a household name at this point. Amyloid β oligomers: ◇ Brain cell death ◇ Excitotoxicity ◇ Oxidative stress ◇ Neurotransmission imbalances ◇ Ion flux disruptions ◇ Inhibition of mitochondrial enzymes ◇ Mitochondrial membrane depolarization ◇ Inhibition of memory formation ◇ Inflammation ◇ Increased calcium uptake ◇ Impaired BDNF / TRKB signaling, ◇ Increased MMP9, which degrades neuron growth factor So yeah, it's definitely bad. HOWEVER, focusing on removing it, aka Pharma's approach, clearly is lackluster, at best. The goal is - how can we: 1. Reduce harmful amyloid production to begin with 2. Reduce its toxicity of it does get formed

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Tau proteins are also a key player. These are proteins that wrap around structural proteins called microtubules. They can become detached and drive all sorts of problems: ↦ Drive inflammation ↦ Cause oxidative stress ↦ Directly neurotoxic Tau proteins actually induce chain reactions where they promote their own production, too. This is probably why Alzheimer's is a progressive condition in most instances. But again, we are left asking how we can: 1. Reduce harmful tau hyperphosphorylation to begin with 2. Reduce its toxicity of it does get formed

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INFLAMMATION promotes amyloid production. When neurons are exposed to inflammatory stimuli, they undergo molecular cascades that actually promote the cross seeding of amyloid peptides. This cross seeding is what makes amyloid pathogenic. https://t.co/G8Rfk4s0g8

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Inflammation drives tau phosphorylation, and vice versa. Inflammatory proteins can directly activate enzymes that phosphorylate tau, making it pathogenic. Amyloid production ALSO increases tau phosphorylation, by increasing inflammation. https://t.co/xt2BRWJa1S

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What is the inflammatory stimuli? Well, it is often LPS (endotoxin). This is a component of bacteria from the gut. If your gut is unhealthy, it actually invades every inch of your body and drives inflammation + disease. Fix your gut first.

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READ THIS IF YOU WANT TO FIX YOUR GUT. If you have IBS, bloating, gas, poor bowel movements or brain fog, you NEED to see this. This is a comprehensive DEEP dive into fixing your digestive health:

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Oxidative stress promotes amyloid production. Increasing oxidative stress promotes the production of amyloid from its precursor. Oxidative stress is when free radical production overrides our antioxidant capacity. Inflammation drives oxidative stress (and vice versa). https://t.co/WMHnh6MY4c

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SEED OILS in Alzheimer's. Lipid peroxidation causes proteins to tangle up - which is seen in Alzheimer's. Lipid peroxidation is the process by which oxidative stress damaged the fats in our tissues. Specifically, the omega 6 fat linoleic acid, found mainly in SEED OILS. https://t.co/wbtjuU9EqU

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Amyloid plaques drive oxidative stress + lipid peroxidation. All of these processes are bidirectional - but by focusing on the core causes we can address it from all angles. Avoiding seed oils to minimize lipid peroxidation is paramount. https://t.co/CC3DwvYX7h

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Vitamin E prevents Alzheimer's disease. Dementia patients given 2,000 IU / d of vitamin E improved cognition and slowed disease progression. Vitamin E is our body's natural antioxidant to stop lipid peroxidation. More on the role / benefits of vitamin E below. https://t.co/qjegEnkzw8

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The universal protector. For the poisons of the modern world, VITAMIN E is one of the best tools to maintain your health. Here's why:

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One cause of oxidative stress and lipid peroxidation is TOXIC/HEAVY METALS. Aluminum levels are high in the Alzheimer's brain. ⊛ Causes brain atrophy ⊛ Drives plaque deposition ⊛ Induces oxidative stress, inflammation It's in plenty of foods and drugs (especially vaccines). https://t.co/GBsoy2JxXn

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N-acetylcysteine (NAC) reverses brain damage from aluminum. NAC ups our levels of glutathione - a master antioxidant / detoxifying peptide in the body. This gives it protective properties against oxidative stress insults to the brain. More on NAC below. https://t.co/xmJKOtDkfU

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N-Acetylcysteine (NAC) is potent anti-aging medicine. It extends lifespan, lowers inflammation, improves metabolism and even sexual function. Let's cover the numerous benefits, the science and how you can implement it:

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N-Acetylcysteine is a mental health marvel. From anxiety, to ADHD, autism and even suicidal depression, it acts as a master mood stabilizer. Let's talk about the benefits of NAC, the science and how to use it yourself:

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Mushrooms cut risk of Alzheimer's, dementia by over half. One serving of mushrooms / week cuts risk by 75%. This is likely due to the high ergothioneine content of mushrooms - a powerful antioxidant whose levels are low in Alzheimer's. More on the incredible mushrooms below. https://t.co/7IfVEDIio8

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Other ways to support your antioxidant system: ☆ Vitamin C ☆ B1 ☆ B2 ☆ Selenium ☆ Copper ☆ Zinc ☆ NAc ☆ Glycine ☆ Taurine ☆ Red / near infrared / sun light ☆ Foods rich in these nutrients (liver, oysters, meat, gelatinous foods) ☆ Foods rich in flavonoids (fruits, whole juices, coffee, chocolate) ☆ Plenty of carbohydrates ☆ Run iron labs, potentially some more comprehensive panels if serious enough

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Glutamate excess kills brain cells. An excess of glutamate, the primary excitatory neurotransmitter, is another cause of brain cell death. GABA is the primary inhibitory neurotransmitter - opposing glutamate's effects. Things that increase GABA are therapeutic in Alzheimer's. https://t.co/8vd03HDjd3

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Glutamate can exert this toxicity through the NMDA receptors. Some tools that promote GABA / lower glutamate / block NMDA receptors: ◇ Magnesium ◇ Zinc ◇ Agmatine ◇ Oral GABA ◇ Pregnenolone / Progesterone ◇ Theanine ◇ NAC ◇ Taurine

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Pregnenolone metabolite therapeutic for Alzheimer's. Allopregnanolone: • Decreases hippocampal (brain region) volume loss • Promotes myelination • Increases neuron fiber density • Increases brain connectivity Achievable with 20+ mg doses oral pregnenolone/progesterone. https://t.co/ioLXRTZ1J2

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Your body’s ultimate neuroprotective, mood enhancing, and mental health bolstering endogenous steroid: PREGNENOLONE

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Magnesium l-threonate improves cognitive function. ⇒ Executive function ⇒ Impulsivity ⇒ Visual search ⇒ Visual attention ⇒ Motor speed ⇒ Working memory ⇒ Object/facial recognition ⇒ Overall cognition improved with this form of magnesium - optimized for brain delivery. https://t.co/oU2fhLyc0Q

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Vitamin D protects against brain cell death. Vitamin D regulates calcium metabolism at many levels. In brain cells, it prevents the excessive uptake of calcium, which is the key event that causes neuron death from glutamate. I've written all about vitamin D below. https://t.co/Tgzod48Ogu

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The FREE vitamin that NO ONE gets enough of. WAY beyond preventing colds, it enhances brain function, crushes stress and massively improves energy. Let's talk about the multifaceted benefits of VITAMIN D:

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Taurine improves Alzheimer's. Increases glucose metabolism in the brain (red). Taurine works on several of the key mechanisms we discusses: ● Improves antioxidant status ● Lowers inflammation ● Enhances mitochondrial function ● Decreases excitotoxicity https://t.co/39BHNYzVkR

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Enhancing glymphatic clearance is also key in preventing cognitive decline. There is lymphatic fluid surrounding the brain that accumulates toxins, including the tau and amyloid proteins. Without proper lymph flow, these proteins accumulate and cause all of these issues. https://t.co/OMtOxnXlUQ

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In fact, stimulating glymphatic clearance is already being used successfully for Alzheimer's.

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Rapid recovery from Alzheimer's by enhancing lymphatic drainage. The brain can accumulate toxic proteins Tau + β-Amyloid plaques, over time resulting in Alzheimer's. The lymphatic system is there to drain out this "waste," but this process can become impaired and predisposes to cognitive decline. Here, surgery to enhance lymph draining from the brain recovered memory within 3 days.

Video Transcript AI Summary

儿子陈曦，陈曦还好吗？吃一碗，吃两碗，一碗可以的。你喜欢吃面还是吃米饭？吃米饭。儿子叫什么名字？陈曦。女儿呢？秋月。求医师，求医师，求医师，求医师。父亲爱你们。慢点，慢点。 English translation: Son Chen Xi, is Chen Xi doing well? Eat one bowl, eat two bowls, one bowl is okay. Do you like noodles or rice? Eat rice. What's your son's name? Chen Xi. And your daughter? Qiuyue. Seeking a doctor, seeking a doctor, seeking a doctor, seeking a doctor. Father loves you. Slowly, slowly.

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Speaker 0: 等后我们就把打量放拔掉儿子陈曦陈曦陈曦还好吗吃一碗吃两碗一碗可以的你喜欢吃面还是吃米饭是吃饭吃米饭儿子叫什么名字啊请谢女儿呢秋月请求医师求医师求医师求医师父亲爱你们不知道慢点慢点慢点慢点慢点慢点慢点慢点慢点慢点慢点慢点慢点

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If you feel puffy, have “cortisol face,” are congested and feel like your body needs a reset, look no further. You’re probably filled up with fluid that won’t leave until you address this. Let’s talk about the LYMPH STAGNATION - why it is harmful & how to fix it:

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Infrared light reduces accumulation of these proteins by supporting lymphatic clearance. Infrared light improves lymph drainage from the brain. This type of light is abundant in sunlight. https://t.co/q8xrLInHLv

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Lymph clearance is also inhibited by the sympathetic nervous system, and enhanced by parasympathetic tone. Dampening the sympathetic + promoting parasympathetic: • Grounding • Humming • Breathing practices • Pets • Plants • Carnosine • Nose breathing https://t.co/VyXJpVeMZP

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Glymphatic clearance is also highest during sleep, especially if you sleep on your side. Optimizing sleep in general is going to be key. People who don't sleep enough or sleep poorly have higher risks of Alzheimer's. Below are some reasons why your sleep might suck. https://t.co/rBrycZB8Xj

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WHY YOU CAN'T SLEEP - 10 reasons you aren't considering: 1. Gut health: irritation and inflammation stemming from the gut can trigger the stress systems, which interrupt sleep patterns. 2. High protein dinner: during sleep, the levels of amino acid derived neurotransmitters are low. Eating high protein can cause elevations in these, contributing to wakefulness. 3. Sleeping too soon after dinner: Ideally, you give your meal time to empty out of your stomach and begin absorption. 1-3 hours after dinner, preferably with a post meal walk, would be optimal. 4. Circadian rhythm: How can you expect your body to know when to sleep if it doesn't even know what time of the day it is? Keeping consistent sleep + wake times is vital, your body will get better at both. 5. Light: Part of keeping a good circadian rhythm is to expose your eyes to bright morning sunlight - ideally sunrise. Then again periodically throughout the day, and ideally sunset as well. Then, keep things dark or free of artificial blue light. Blue blockers are awesome for this. 6. Journaling + planning: sometimes, it's hard to get to bed because you have a bunch of things to think about for the next day. A good way to get rid of this is to write it down, that way your brain isn't constantly trying to remember what to do next. 7. Not enough calories: restricting calories is a good way to increase the stress systems. No need to stuff your face, but eat to satiety. Hunger is one of the ultimate signals to stay awake. 8. A low carb dinner: if you ever wake up in the middle of the night thirsty or craving something sweet, chances are you've gone hypoglycemic. That's because you didn't eat enough carbs at your last meal and now your tank (liver) is empty. Carbing up before bed is the way to go, adding a bit of fat can help to slow the absorption making it last even longer. 9. Poor liver function: similar story here, if your liver isn't working well, it will have a tough time storing carbohydrate to keep you well fueled through the night. Taurine can help with this, glycine, caffeine, vitamin K2 are some other liver protective tools. 10. Not enough salt: salt helps suppress adrenaline and other stress hormones, notably antidiuretic hormone, which prevents you from peeing during the night. Good dinners would be gelatinous meats (broths, shanks, oxtail), salty + easily digestible starches (mashed potatoes with butter, sourdough bread with olive oil, rice with coconut oil, etc.), and dessert (ice cream, honey, chocolate).

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You can't talk about Alzheimer's without talking about APOE. This is a protein that helps transport cholesterol and other fat soluble molecules between brain cells. It also clears out the toxic amyloid proteins. The APOE4 gene is a huge risk for Alzheimer's, because it: ◇ Causes accumulation of lipids in cells - driving inflammation and mitochondrial dysfunction ◇ Decreases amyloid clearance ◇ Promotes lymphosclerosis - which impairs lymph flow 14% of people have it.

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HOWEVER, this doesn't mean you automatically are screwed. For example, in Nigeria, Alzheimer's is very rare despite a high prevalence of APOE4. Just goes to show that YOU are in charge, not your genetics. https://t.co/aXiltBopPS

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Finally, anything that can help stimulate brain cell growth, mainly through BDNF or NGF, is likely to be beneficial. After all, Alzheimer's is all about brain cell death, so encouraging them to survive should be good. https://t.co/5Oy0vHLfiM

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Fresh orange juice improves cognitive function. OJ: ➜ Stimulates BDNF (brain cell growth + development) ➜ Lowers nitric oxide (brain inflammation / oxidative stress) ➜ Lowers endotoxin ➜ Improves glucose metabolism Which combine to improve mental performance metrics. https://t.co/EfP7tRcbn3

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Orange juice is literally one of the healthiest foods on the planet. It has proven antidepressant, anti-inflammatory, anti-diabetic and gut health promoting properties. Don’t believe me? Let’s get into it:

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6 months of lifting weights was shown to improve antioxidant status, which downstream upregulates the expression of BDNF - a protein that has powerful antidepressant and neuron growth promoting properties. Also should be good for cognitive decline. https://t.co/EHoSYwJDNd

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DHEA activates the BDNF receptor, growing new brain cells. DHEA is one of our "youth associated steroid" hormones that decline with age. Part of its protective effect is to support neurogenesis by activating the TrkB receptor - normally activated by BDNF. https://t.co/6xv5jZkPMK

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DHEA: a fountain of youth. For lowering cortisol, improving cognitive function & mood, vibrant skin and fat loss, it might be just what you need. Here’s why researchers have called aging “DHEA deficiency syndrome:”

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Lion's mane powerfully regenerates the brain. Extracts of the mushroom showed huge increases in the length and number of neural projections. Various components in mushrooms have TrkB activity - promoting BDNF signaling that drives brain cell growth & maturity. https://t.co/GNNQX9gOTS

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Posted - June 25, 2025 at 3:21 PM

Saved - June 25, 2025 at 4:59 PM

reSee.it AI Summary

I've been exploring the concept of brain fog, particularly its connection to long COVID. It's now recognized as a significant issue, primarily driven by inflammation and a compromised blood-brain barrier, often linked to gut health. Conditions like SIBO and celiac disease exacerbate symptoms. To address this, I've outlined steps to reduce endotoxin absorption, eliminate harmful bacteria, and heal the gut lining. Additionally, I've highlighted the importance of clearing the glymphatic system and using anti-inflammatory remedies like luteolin. Other factors, such as mold, heavy metals, and hypothyroidism, can also contribute to brain fog.

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BRAIN FOG: It all comes down to ONE thing. Brain fog wasn't something that was even recognized in medicine, but that all changed over the last few years. The amount of people complaining about brain fog became too much to ignore. Now, we have the answer: https://t.co/kQm70M3GiZ

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Brain fog is one of the most common + debilitating symptoms of long COVID. This forced science to devote attention + resources to understanding it. The causes of it were discovered: 1. Inflammation 2. A leaky brain These issues are the driving force behind ALL brain fog. https://t.co/bIVO6Mk2DB

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BRAIN FOG is INFLAMMATION. People with it have higher inflammatory markers: ➜ IL-6 ➜ IL-8 ➜ MCP-1 ➜ IL-13 ➜ IL1RA ➜ IFN-γ The more severe the fog, the more inflammation there is. https://t.co/gGEB8StyhI

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LEAKY BRAIN also drives brain fog. The vessels supplying blood to the brain can become compromised, and this allows: ➜ Toxins ➜ Immune cells / inflammatory proteins ➜ Pathogens into the brain. More blood brain barrier permeability = more brain fog. https://t.co/tqKykOfvDE

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But where does the inflammation and leaky brain come from? While most of the attention on COVID was directed towards its respiratory effects, COVID actually destroys the GUT, and this is responsible a ton of the severe disease. This is also ground zero for brain fog. https://t.co/dGyRqZkdtJ

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Brain fog is VERY common in people with gut issues. ➜ SIBO ➜ IBS ➜ IBDs often times, probiotics can actually make it worse, and antibiotics can improve it. This tells us that bacterial overgrowth / leakage is the primary mediator of brain fog. https://t.co/E31CgIqsQe

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In fact ~90% of celiac + gluten sensitive people report symptoms of brain fog. This tells us that gut inflammation itself is enough to drive the symptoms of brain fog. This is because inflammation is never completely localized - the signals extend throughout the entire body. https://t.co/CeTkVfeiDd

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Leaky brain is caused by systemic inflammation. Inflammatory components: ◆ Endotoxin ◆ Cytokines (TNF-α, IL-1β, IL-6, IFN-γ) ◆ High-mobility group box‐1 ◆ Cyclophilin A ◆ Sphingosine ◆ Complement components ◆ Kinins ◆ Prostaglandins ◆ Serotonin ◆ Histamine ◆ Arachidonic acid can ALL make the blood vessels more permeable.

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Inflammation poisons the brain All of these signals: ➔ Impair neurogenesis (new brain cell formation) ➔ Alter synaptic plasticity ➔ Disrupt neurotransmitter release ➔ Wreck mitochondrial energy production ➔ Kills brain cells (ROS) thus, you get brain fog. https://t.co/Ya78gc5qfB

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So the simplest way of describing brain fog is: 1. You have bacterial dysbiosis / leaky / inflamed gut 2. Systemic inflammation ensues 3. The blood brain barrier opens 4. You get inflammation in the brain 5. Brain fog So, we have to focus on the gut, first and foremost.

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2 easy and free ways to tell if you have dysbiosis: 1. Coated tongue in the morning (especially in the back) 2. Consistent foamy urine If these are prevalent along with: 1. Other gut symptoms 2. Brain fog (especially post meal) your gut bacteria are probably messed up. https://t.co/G0pUsRIof9

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Step 1: Reduce endotoxin absorption. Endotoxin is one of the most powerful inflammatory signals in the entire body, and it comes from the bacteria in your gut. Meals higher in fat = higher absorption of endotoxin Fiber = prevents absorption but this only mitigates the underlying issue ⬇️

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Step 2: Kill the bad bacteria This is likely THE primary reason behind the gut (& thus systemic) inflammation. ⬩Oregano oil ⬩Allicin (garlic/onion) ⬩Mastic gum ⬩Ginger ⬩Pau D'Arco ⬩Rosemary ⬩Thyme ⬩Activated charcoal ⬩Wormwood ⬩Camphor ⬩Carrot ⬩Berberine ⬩Vitamin D ⬩Vitamin K2 ⬩Zinc ⬩Lactoferrin are just a few natural antimicrobials that can help.

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Step 3: Heal the gut lining ➞ Zinc (carnosine) ➞ Butyrate (or tributyrin) ➞ Lactoferrin ➞ L-Glutamine ➞ N-Acetyl glucosamine ➞ Collagen ➞ Phosphatidylcholine ➞ Aloe vera ➞ Colostrum are some of the best ways to seal up the gut lining. This reduces systemic inflammation + brain fog.

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A fascinating finding is that CO2 or bicarbonate is actually low in post-COVID brain fog. CO2 has an anti-inflammatory effect, and low levels of it (or bicarbonate) predict poorer outcomes, including brain fog. Where you can get some extra bicarbonate? Check the thread below. https://t.co/Sc6bfWw4cZ

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The most potent medicine in your house is literally sitting in your cabinet, and cost you next to nothing. It combats fatigue, inflammation, stress and even cancer. You won’t believe the incredible health benefits of BAKING SODA:

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Another huge key to reducing inflammation in the brain specifically is to clear out the glymphatic system. Glymphatic fluid contains cellular waste, immune cells and toxins - and they can become more concentrated with a "leaky brain." This drives inflammation in the brain.

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Your brain accumulates waste that makes you tired and ends up giving you dementia. Luckily, these 7 techniques enhance its clearance to help keep your mind sharp. #1 Sleeping on your side https://t.co/P11PCnvWce

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The glymphatic system, the brain's waste removal system, is most active during sleep. Side sleeping enhances this process by up to 25% compared to other positions. This system removes toxic proteins that can lead to neurodegeneration. Proper sleep position can improve memory consolidation by 20% and reduce brain inflammation. It helps clear proteins linked to Alzheimer's and may speed recovery from concussion. The brain detoxifies better in certain positions. Sleeping on your right side with your head slightly elevated is recommended. Use a cervical pillow to maintain proper spine alignment and avoid stomach sleeping, which restricts blood flow to the brain.

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Speaker 0: The way you sleep could be clogging or cleaning your brain. Here's the science: Your brain has a waste removal system called the glymphatic system that's most active during sleep. Side sleeping enhances this process by up to 25% compared to other positions. This system removes toxic proteins that can lead to neurodegeneration. Proper sleep position can improve memory consolidation by 20% and reduce brain inflammation. It helps clear proteins linked to Alzheimer's and may speed recovery from concussion. Your brain literally detoxifies better in certain positions. Isn't that strange? Start sleeping on your right side with your head slightly elevated. Use a cervical pillow to maintain proper spine alignment and avoid stomach sleeping which restricts blood flow to the brain.

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Luteolin is a powerful remedy for brain fog. This is a flavonoid in foods like broccoli, onions, and apples, and has the unique capability to inhibit the activation of: ➜ Mast cells ➜ Microglia which are 2 of the most prominent inflammatory cells in the brain. https://t.co/EPOonMQYrb

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A comprehensive list of direct acting, anti-inflammatories for the brain (specifically microglia): ◆ Lithium ◆ Aspirin ◆ Taurine ◆ Glycine ◆ L-Theanine ◆ Luteolin ◆ Apigenin ◆ Baicalein ◆ Fisetin ◆ Palmitoylethanolamide (PEA) ◆ Oleoylethanolamide (OEA) ◆ DHA ◆ Melatonin ◆ Allopregnanolone (from progesterone) ◆ Pregnenolone ◆ Vitamin D ◆ Curcumin ◆ Resveratrol ◆ EGCG ◆ Honokiol ◆ Apocynin ◆ Hydrogen ◆ Escin ◆ Acacetin ◆ β-aminoisobutyric acid ◆ Corydecumine G ◆ Linarin ◆ Oxymatrine ◆ Panaxytriol ◆ Esculentoside A

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There are other important sources of persistent inflammation to consider that can also contribute. One I've written about recently is mold https://t.co/JfFPkQJrTi

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MOLD: The hidden cause behind your gut issues & fatigue that your doctor can't figure out. This is a DEEP dive on mold / mycotoxins - how to know if it's an issue for you and what to do about it to get back to feeling your best: https://t.co/vqtn3US03t

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Heavy metals are another https://t.co/pEirtjZt5B

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The poisons WRECKING your health that your doctor doesn’t want to talk about. This is the COMPLETE GUIDE to TOXIC HEAVY METALS - how you get exposed, sick, and what to do about it:

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Hypothyroidism can also cause brain fog. Roughly HALF of people officially diagnosed will experience it. The master guide to thyroid optimization can be found below. https://t.co/W5nrGK3YkY https://t.co/tzl8onThMg

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The key to unlocking your metabolism, mood, energy and gut health is sitting under your tongue being ignored by your doctor. This is the ULTIMATE AND COMPLETE GUIDE TO THYROID HEALTH so you can optimize it:

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Posted - June 23, 2025 at 2:23 PM

Saved - June 24, 2025 at 6:59 PM

reSee.it AI Summary

Pornography is causing significant harm, with a staggering number of children exposed to it. Many adults recognize its problematic nature, yet consumption remains high. Regular viewers often experience guilt, shame, and declining sexual desire, leading to issues like erectile dysfunction. The brain's response to porn mirrors addiction, with desensitization to real intimacy and an increased tolerance for violent content. This behavior correlates with domestic abuse and relationship dissatisfaction, suggesting that porn may contribute to rising divorce rates.

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Porn is inflicting massive destruction upon us. It's so normalized that even 75% of children have seen it. This has gotten completely out of hand. Porn is a drug, and it can distort reality, alter your brain & ruin relationships. We have the science to prove it:

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By any measure, the vast majority of people in the western world watch porn regularly. Up to around 70% of people feel it is problematic in some way shape or form, and 14% of people end up seeking treatment to stop watching it.

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The statistics on pornography are downright disturbing. 62% feel guilt or shame in watching it. A staggering 47% of consumers watch content that they did not previously think was stimulating - including what they used to think was disgusting.

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The high rates of pornography consumption are NOT due to high sex drive. In fact, you’re more likely to have LOW arousal to actual women as a porn watching man. We see this time and time again.

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Frequent porn users produce LESS dopamine in response to things that excite them sexually, but HIGHER dopamine in response to "explicit" sexual content, even if they didn't like it. What does this mean? The brain fundamentally perceives sex & porn differently.

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Porn & gambling act similarly in the brain. Both involve overactive “wanting” in response to cues, with intact or even blunted “liking” during reward receipt. Something you want even or need, even when the reward fades. So, an addiction.

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People who watch porn also crave NEW sexual images more than those who do not. The dACC (dorsal anterior cingulate cortex) also shows more rapid habituation to images than healthy controls - a brain region involved in: ➠ Attention ➠ Decision making ➠ Impulse control

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More porn ➜ less brain volume in dopaminergic regions, mediating functions like: ⬩Memory ⬩Impulse control ⬩Reward ⬩Hyperactivity ⬩Learning + decreased connectivity to higher thinking brain regions. This parallels what is seen in other drug / behavioral addictions.

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New sexual partners stimulate the reward system more than familiar ones. Now imagine you have instant access to hundreds of new "partners" in seconds. A rapid, massive, unnatural spike in dopamine that your brain becomes accustomed to but still craves. So, an addictive drug.

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Watching porn regularly causes RAPID ESCALATION to violent sexual practices (bondage, sadomasochism) and even bestiality. This is the result of the brain rapidly adapting to normal sexual stimulus. Kind of like how drug addicts need to up their dose to get the same high.

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Erection quality declines with repeated exposure to porn as well. Penis circumference is reduced, but rebounds to normal if subjects stop watching it for a few weeks.

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Knowing all of this, it's very likely that porn is driving a generation of sexual dysfunction. Erectile dysfunction in young men was <5% in 2000. In 2015, that number was up to ~30%. The vast majority of these cases are NOT physical - they are psychological.

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Erectile dysfunction is often accompanied by ED accompanied by a low desire for partnered sex is now a common observation in clinical practice among men seeking help for their excessive sexual behavior, who frequently “use pornography and masturbate”

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Multiple doctors have written about treating patients for sexual dysfunction simply by removing porn. Urology professor Harry Fisch + psychiatry professor Norman Doidge both documented it in their books.

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Watching porn can drive ED - stopping can reverse it. Multiple reports that men who: Had sexual issues ➜ went to doctors ➜ told them to stop watching porn ➜ rapid resolution of symptoms. The reward system becomes habituated, but can rebound.

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Low sexual desire in young males does not exist without porn. 0% of young males reported this as a problem if they didn't watch porn. 6% did if they watched it less than once per week. 16% did if they watched it more than once per week.

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Watching porn causes changes to the brain, and to perspectives on sex, cultivating in some disastrous consequences. Porn exposure increases tolerance for abusing women. Watching it causes viewers to rapidly escalate to violent content, so this should come as no surprise.

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"Under controlled experimental conditions, massive exposure to pornography resulted in a loss of compassion toward women as rape victims and toward women in general." I mean, do I need to say any more?

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The more porn people watch, the more okay they become with rape. People with zero exposure to porn reported that they thought the crime of rape was about twice as bad as those with lots of exposure.

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Problematic porn use correlates with domestic abuse. Among 273 men in batterer-intervention programs, higher addiction-like porn use predicted both physical and sexual abuse, even after adjusting for substance use, PTSD, depression, and antisocial traits.

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Watching porn promotes rape acceptance. In multiple meta studies, porn use was linked to belief in harmful narratives about sexual abuse (e.g., "she was asking for it").

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Women who actively seek out porn are more likely to use sexual coercion. Higher porn effort predicted: ◇ Emotional manipulation ◇ Exploiting intoxicated partners ◇ Persistent nonverbal arousal

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Porn consumption is associated with committing acts of sexual aggression. Tracking people who watch porn over time shows that they are more likely to commit sexual harm.

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Finally, porn can ruin relationships. Women reported that they felt more disconnected from their partners if they watched porn (duh). Men reported the same for their own use.

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Porn might be a key explanation behind high divorce rates. The earlier you start watching porn, the higher the divorce rate. Starting at age 20, the rate is over 50%. Under 10% for those who never watched.

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And it's hard to argue it's not causation. Longitudinal studies examine people over time, to help assess what comes first. "The most important implication of these results is that *longitudinally* the link between SEIM use and relationship quality seems to work both ways. Husbands in poor relationships use more SEIM **and more SEIM among husbands leads to poorer relationships**" [SEIM = sexually explicit internet materials)

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SOURCES https://academic.oup.com/jsm/article-abstract/13/5/760/6940239?redirectedFrom=fulltext https://pmc.ncbi.nlm.nih.gov/articles/PMC6352245/#sec3-jcm-08-00091 addiction revs (up to 10% https://sci-hub.se/10.1080/10720160903300788 y 20-60% find it problematic https://sci-hub.se/10.1016/j.chb.2015.11.046 14-16% report at work use, 28% problematic PPC/compulsive/addiction - may not affect everyone watching porn, but it definitely CAN’T affect you if you don’t watch it. Treat it as a drug. COOLIDGE EFFECT https://pubmed.ncbi.nlm.nih.gov/39212871/ porn arousal = decline in satisfaction / relationship qual over 2 months https://academic.oup.com/hcr/article-abstract/35/2/171/4107460?redirectedFrom=fulltext reduced sexual satisfaction https://www.mdpi.com/2076-328X/6/3/17 clinical reports - this pretty much answers all questions about causality - see saved PDF rise of ED https://publichealth.jmir.org/2021/10/e32542 “This prevalence of ED in young men is alarmingly high, and the results of this study suggest a significant association with PPC.” - starting @ younger age = more porn watching, porn addiction = ED, more consumption = more ED, higher addiction scores - more ED https://www.nature.com/articles/npp201778 https://academic.oup.com/brain/article-abstract/136/8/2527/425092?redirectedFrom=fulltext&login=false brains studies https://www.enough.org/objects/Till_Porn_Do_Us_Part_A_Longitudinal_Exam_fnv.pdf more likely to divorce if you started watching porn @ young age https://pubmed.ncbi.nlm.nih.gov/20174862/ women more likely to indicate they had less sex as a result of a partner’s OSA, and men more likely to indicate they were less aroused by real sex as a result of their own OSA. https://www.sciencedirect.com/science/article/pii/S0747563214006955#b0165 The most important implication of these results is that longitudinally, the link between SEIM use and relationship quality seems to work both ways, but only for husbands. Husbands in poor relationships use more SEIM and more SEIM among husbands leads to poorer relationships. https://sci-hub.se/10.1111/j.1540-4560.1973.tb00092.x https://sci-hub.se/10.1176/ajp.128.5.575 https://sci-hub.se/10.1111/j.1460-2466.1982.tb02514.x https://sci-hub.se/10.1177/009365086013004003 Escalation, violence, rape https://sci-hub.se/10.1007/s10508-014-0291-5 https://pubmed.ncbi.nlm.nih.gov/19862768/ makes u ok with abusing women https://pmc.ncbi.nlm.nih.gov/articles/PMC6942232/ more on violence https://www.tandfonline.com/doi/abs/10.1080/01639620802589798 https://link.springer.com/article/10.1007/s10508-019-01538-4?fromPaywallRec=false https://onlinelibrary.wiley.com/doi/abs/10.1111/jcom.12201 coercion https://www.sciencedirect.com/science/article/pii/S0022395615003131 Internet pornography users show stronger preference for novel sexual images than healthy controls, their dACC (dorsal anterior cingulate cortex) also shows more rapid habituation to images than healthy controls

Online Porn Addiction: What We Know and What We Don’t—A Systematic Review In the last few years, there has been a wave of articles related to behavioral addictions; some of them have a focus on online pornography addiction. However, despite all efforts, we are still unable to profile when engaging in this behavior becomes ... pmc.ncbi.nlm.nih.gov

Porn or Partner Arousal? When It Comes to Romantic Relationships, Not All Sexual Arousal Is Equal: A Prospective Study - PubMed Little is known about the role of subjective sexual arousal within romantic relationships. The current paper addresses this limitation using a prospective study design that investigates the direct associations between subjective sexual arousal induced by a romantic partner (partner arousal) and arou … pubmed.ncbi.nlm.nih.gov

Is Internet Pornography Causing Sexual Dysfunctions? A Review with Clinical Reports Traditional factors that once explained men’s sexual difficulties appear insufficient to account for the sharp rise in erectile dysfunction, delayed ejaculation, decreased sexual satisfaction, and diminished libido during partnered sex in men under 40. This review (1) considers data from multiple domains, e.g., clinical, biological (addiction/urology), psychological (sexual conditioning), sociological; and (2) presents a series of clinical reports, all with the aim of proposing a possible direction for future research of this phenomenon. Alterations to the brain's motivational system are explored as a possible etiology underlying pornography-related sexual dysfunctions. This review also considers evidence that Internet pornography’s unique properties (limitless novelty, potential for easy escalation to more extreme material, video format, etc.) may be potent enough to condition sexual arousal to aspects of Internet pornography use that do not readily transition to real-life partners, such that sex with desired partners may not register as meeting expectations and arousal declines. Clinical reports suggest that terminating Internet pornography use is sometimes sufficient to reverse negative effects, underscoring the need for extensive investigation using methodologies that have subjects remove the variable of Internet pornography use. In the interim, a simple diagnostic protocol for assessing patients with porn-induced sexual dysfunction is put forth. mdpi.com

Associations Between Online Pornography Consumption and Sexual Dysfunction in Young Men: Multivariate Analysis Based on an International Web-Based Survey Background: Expanding access to the internet has resulted in more and earlier consumption of online pornography. At the same time, a higher prevalence of erectile dysfunction (ED) among young men is seen. Increased pornography consumption has been suggested as a possible explanation for this rise. Objective: The aim of this study was to better understand associations between problematic pornography consumption (PPC) and ED. Methods: A 118-item survey was published online, and data collection took place between April 2019 and May 2020. Of the 5770 men who responded, the responses from 3419 men between 18 years old and 35 years old were analyzed. The survey used validated questionnaires such as the Cyber Pornography Addiction Test (CYPAT), International Index of Erectile Function (IIEF-5), and Alcohol Use Disorders Identification Test-Concise (AUDIT-C). The estimated amount of porn watching was calculated. Univariable and multivariable analyses were performed. For the multivariable analysis, a logistic regression model using a directed acyclic graph was used. Results: According to their IIEF-5 scores, 21.48% (444/2067) of our sexually active participants (ie, those who attempted penetrative sex in the previous 4 weeks) had some degree of ED. Higher CYPAT scores indicating problematic online pornography consumption resulted in a higher probability of ED, while controlling for covariates. Masturbation frequency seemed not to be a significant factor when assessing ED. Conclusions: This prevalence of ED in young men is alarmingly high, and the results of this study suggest a significant association with PPC. Trial Registration: Research Registry researchregistry5111; https://tinyurl.com/m45mcaa2 publichealth.jmir.org

Can Pornography be Addictive? An fMRI Study of Men Seeking Treatment for Problematic Pornography Use - Neuropsychopharmacology Pornography consumption is highly prevalent, particularly among young adult males. For some individuals, problematic pornography use (PPU) is a reason for seeking treatment. Despite the pervasiveness of pornography, PPU appears under-investigated, including with respect to the underlying neural mechanisms. Using functional magnetic resonance imaging (fMRI), we examined ventral striatal responses to erotic and monetary stimuli, disentangling cue-related ‘wanting’ from reward-related ‘liking’ among 28 heterosexual males seeking treatment for PPU and 24 heterosexual males without PPU. Subjects engaged in an incentive delay task in the scanner, in which they received erotic or monetary rewards preceded by predictive cues. Blood-oxygen-level-dependent responses to erotic and monetary cues were analyzed and examined with respect to self-reported data on sexual activity collected over the 2 preceding months. Men with and without PPU differed in their striatal responses to cues predicting erotic pictures but not in their responses to erotic pictures. PPU subjects when compared with control subjects showed increased activation of ventral striatum specifically for cues predicting erotic pictures but not for cues predicting monetary gains. Relative sensitivity to cues predicting erotic pictures vs monetary gains was significantly related to the increased behavioral motivation to view erotic images (suggestive of higher ‘wanting’), severity of PPU, amount of pornography use per week, and number of weekly masturbations. Our findings suggest that, similar to what is observed in substance and gambling addictions, the neural and behavioral mechanisms associated with the anticipatory processing of cues specifically predicting erotic rewards relate importantly to clinically relevant features of PPU. These findings suggest that PPU may represent a behavioral addiction and that interventions helpful in targeting behavioral and substance addictions warrant consideration for adaptation and use in helping men with PPU. nature.com

Perceived consequences of casual online sexual activities on heterosexual relationships: a u.s. Online survey - PubMed Some researchers have illustrated how the Internet can provide users with an ideal atmosphere to explore sexuality; however, most have stressed the Internet's negative impact on intimate relationships. Notably, much of this research has focused on the small minority of men who compulsively engage in … pubmed.ncbi.nlm.nih.gov

Internet pornography and relationship quality: A longitudinal study of within and between partner effects of adjustment, sexual satisfaction and sexually explicit internet material among newly-weds Several studies have established a negative relation between the use of sexually explicit Internet material (SEIM) and relationship quality. While mos… sciencedirect.com

Pornography and attitudes supporting violence against women: revisiting the relationship in nonexperimental studies - PubMed A meta-analysis was conducted to determine whether nonexperimental studies revealed an association between men's pornography consumption and their attitudes supporting violence against women. The meta-analysis corrected problems with a previously published meta-analysis and added more recent finding … pubmed.ncbi.nlm.nih.gov

Problematic Pornography Use and Physical and Sexual Intimate Partner Violence Perpetration Among Men in Batterer Intervention Programs Recent decades witnessed a surge in pornography use, contributing to what some researchers referred to as problematic pornography use (PPU; excessive, compulsive, and uncontrollable pornography use). Informed by cognitive scripts theory, ... pmc.ncbi.nlm.nih.gov

Sexual Coercion by Women: The Influence of Pornography and Narcissistic and Histrionic Personality Disorder Traits - Archives of Sexual Behavior Largely overlooked in the literature, this study investigated factors influencing women’s use of sexual coercion. Specifically, pornography use and p link.springer.com

Novelty, conditioning and attentional bias to sexual rewards The Internet provides a large source of novel and rewarding stimuli, particularly with respect to sexually explicit materials. Novelty-seeking and cue… sciencedirect.com

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Erectile dysfunction in young men was <5% in 2000. In 2015, that number was up to ~30%. The vast majority of these cases are not physical - they are psychological. What's going on here?

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Posted - March 12, 2025 at 1:10 PM

Saved - June 23, 2025 at 1:11 AM

reSee.it AI Summary

If you've struggled to lose weight despite trying everything, the issue may lie in your gut. Research shows that gut bacteria significantly influence weight gain and metabolism. Obese individuals have harmful bacteria and higher levels of endotoxin, which can lead to inflammation, insulin resistance, and fat accumulation. Addressing gut health through antibiotics, probiotics, and butyrate can improve metabolism and prevent fat gain. A comprehensive approach to healing the gut is essential for effective weight management, and personalized help is available for those seeking guidance.

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If you've tried EVERYTHING and still can't lose weight, this is for you. This is why your GUT is making you FAT (& what to do about it):

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20 years ago, it was discovered that: 1. Obese people have distinct gut bacteria vs lean people 2. Transferring the gut bacteria from an obese donor to a lean animal makes the animal fat without changing diet. The key is in the gut.

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Shortly after, it was found that animals with NO gut bacteria DO NOT get fat, even with a junk food diet. These animals had: ◇ Improved mitochondrial function (increased PGC1α, AMPK) ◇ Reduced flux of fat into fat tissue making them resistant to getting fat.

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Animals with no gut bacteria gain half the weight they "should" from what they eat. Eliminating the bacteria allowed animals to stay lean despite eating the same amount of calories.

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ENDOTOXIN (LPS) is the primary culprit here. This is a part of most gut bacteria that has a ton of negative effects on the body. ⇨ Triggers inflammation systemically ⇨ Worsens mitochondrial function (energy production) ⇨ Increases serotonin ⇨ Prevents fat from "browning" This means that your metabolism will be ruined with lots of endotoxin, and that can cause weight gain.

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Obese people have "bad bacteria" + more endotoxin. Endotoxin comes from gut bacteria, but it becomes a problem systemically, since it is able to drive "leaky gut." This means the gut becomes porous, and endotoxin can invade other parts of the body. This destroys metabolism.

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Endotoxin (from gut bacteria) causes obesity + insulin resistance, regardless of calories. Administration of endotoxin: ◇ Increases fat gain ◇ Increases insulin ◇ Increases blood sugar ◇ Fattens the liver basically causing diabetes all on its own.

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Antibiotics prevent fat gain and insulin resistance, even when eating junk food. Low dose, broad spectrum antibiotics: ◈ Reduced blood sugar ◈ Reduced insulin ◈ Reduced fat gain despite eating MORE of a fattening diet.

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Antibiotics reverse leaky gut + inflammation. Once again, low dose + broad spectrum antibiotics: ➔ Reduces intestinal permeability ➔ Reduces oxidative stress ➔ Lowers inflammation from a junk food diet. This is the power of reducing endotoxin.

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Gut inflammation makes you fat, by increasing serotonin. Obese individuals have higher serotonin release from the gut than lean people. Serotonin is released when there is endotoxin or other gut inflammation. More on that below.

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YOU MUST ADDRESS THIS TO FIX YOUR GUT This “happy hormone” is the primary driver of digestive problems. I found that out the hard way. Here’s what I’ve learned, how I lowered it and how you can do the same:

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Lowering gut serotonin prevents fat gain, increases metabolism. Serotonin released systemically lowers metabolism. ◇ Prevents "browning" of fat - which increases energy production ◇ Drives insulin resistance ◇ Fattens the liver again, without increasing calories.

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Probiotics can prevent obesity, by reducing serotonin. The bacteria B. Vulgatus was shown to: ◈ Reduce gut serotonin / inflammation ◈ Lower body fat ◈ Increase muscle mass ◈ Prevent liver fat Treating the gut can absolutely help you achieve the body you want.

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Probiotics can prevent obesity. L. Rhamnosus completely prevents fat gain from a junk food diet, without reducing calories. It does this by reducing endotoxin containing bacteria, and also by improving leptin resistance. More on that below.

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The reason you can’t lose weight (or keep it off) no matter how hard you try. LEPTIN: why it’s SO important and how to optimize yours to boost your metabolism and finally stay thin for life.

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Butyrate increases metabolism, prevents fat gain. Butyrate is a product & driver of a healthy gut. It has multiple beneficial effects on mitochondrial function: ➔ Increases PGC1a (multiplies mitochondria) ➔ Ups UCP1 (more heat generation) Giving it anti-obesity properties.

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I've written about the benefits and role of butyrate in the gut here:

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Researchers have called it the guardian of the gut. It is a godsend for IBS, Crohn’s, Ulcerative Colitis and even colon cancer. Why BUTYRATE might be your key optimal digestion + gut health:

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Ultimately, you will want to take a comprehensive approach to healing the gut, especially if your goal is fat loss. Below is my masterclass on doing just that:

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READ THIS IF YOU WANT TO FIX YOUR GUT. If you have IBS, bloating, gas, poor bowel movements or brain fog, you NEED to see this. This is a comprehensive DEEP dive into fixing your digestive health:

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Of course, all of this can be difficult to figure out on your own, but we are here for you. If YOU want personalized help from us with your health, click where it says “schedule a free call” here: http://prism.miami

Prism Health The solution is out there. We can help you find it. prism.miami

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Posted - October 30, 2024 at 1:35 PM

Saved - June 23, 2025 at 1:07 AM

reSee.it AI Summary

I’ve explored various aspects of gut health, emphasizing the importance of addressing dysbiosis, which can lead to symptoms like bloating and gas. I shared simple ways to identify dysbiosis and suggested dietary changes, including low-residue and low-FODMAP diets. Stress and circadian rhythms significantly impact gut function, while nutrients like magnesium and vitamins A and D play crucial roles in managing inflammation. I also discussed the benefits of antimicrobials, probiotics, and supplements like lactoferrin and glutamine for healing the gut.

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READ THIS IF YOU WANT TO FIX YOUR GUT. If you have IBS, bloating, gas, poor bowel movements or brain fog, you NEED to see this. This is a comprehensive DEEP dive into fixing your digestive health:

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The first & most important thing to address is dysbiosis (“bad bacteria” in the gut) It will drive: ⬩Pain⬩Gas⬩Sensitization⬩Bloating⬩Food intolerances⬩Diarrhea⬩Poorly formed stools⬩Constipation⬩Acid reflux⬩& more

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2 easy and free ways to tell if you have dysbiosis: 1. Coated tongue in the morning (especially in the back) 2. Consistent foamy urine If these are prevalent along with other gut symptoms - you can bet dysbiosis is an issue. I go more into that here:

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You probably experience these things, but think nothing of it. Here are 5 "normal" signs that your health is deteriorating, + what causes them, & what to do about it:

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Stool testing can be useful, but the results are highly questionable. Ultimately the results will typically not have much impact on how you move forward. Plus, high quality ones can be quite expensive. There are exceptions, but this is the rule.

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Start with a low residue or low fiber diet that limits bacterial fermentation. All cuts & types of meat, eggs, seafood, dairy as tolerated (cottage cheese + Greek yogurt typically) Easily digestible carbs like fruit juices, cane sugar and honey.

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The foods everyone tells you to eat but are wrecking your digestion. FIBER - why it’s RUINING your gut, and CAUSING constipation:

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A low FODMAP diet can be effective if the problem is more upper GI (belching, upper bloating, lack of appetite). Keep polyunsaturated fats LOW (seed oils mainly). The fats in these oils are absolutely horrible for the gut. I've gone into that here:

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The NUMBER ONE food you need to eliminate to heal your gut. SEED OILS - Why they are destroying your digestion:

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Avoid food additives: added iron, colors, gums, dyes, etc. If you don’t recognize an ingredient, then it’s best to avoid it. These additives disrupt the mucus layer, foster a pathogenic bacterial load, and drive inflammation. More on that here:

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THIS might just be causing your gut problems. The FDA has swept these under the rug for decades. We’re now waking up to the harms of these so-called “safe” ingredients, added to nearly every commercial food. Let’s talk about it⬇️

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As your gut begins to heal, the more you should expand the diet over time. ⬩Fruit⬩Well cooked potatoes / rice⬩Cooked grains (sourdough)⬩Well cooked vegetables⬩ You don't want to have a restrictive diet long term, as this can backfire and limit your progress.

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In general - over or under-eating will make things worse. Listen to your body. You also want to eat a diet that is enjoyable. Eating foods you don’t think are tasty and that you don’t want to eat measurably impairs your digestion:

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Enjoy your meals, it is essential for good digestion. In 1922, Dr. Walter Alvarez stated: ⬩Digestion is faster if food is palatable ⬩Digestion is slower when the food was thought to be disgusting ⬩Animals and people had slower digestion if being fed vs eating on their own.

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ANTIMICROBIALS are a huge part of fixing gut dysbiosis. Very low dose, safe antibiotics can be an absolute life saver. I know a lot of people don’t like to hear this, but using at a microdose & duration is incredibly powerful. Just easy to overdo it.

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Some natural antimicrobials: ⬩Oregano oil⬩Allicin (garlic/onion)⬩Mastic gum ⬩Pau D'Arco⬩Rosemary⬩Thyme⬩Activated charcoal⬩Wormwood⬩Camphor⬩Carrot⬩Berberine⬩Vitamin D⬩Vitamin K2⬩Zinc⬩Lactoferrin⬩

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One herbal protocol that was studied for SIBO. 2 capsules each of proprietary blends (you can get these online) FC Cidal + Dysbiocide or Candibactin-AR + Candibactin-BR, 2x a day for 4 weeks. Equivalent to standard antibiotics in terms of effectiveness.

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PROBIOTICS: I wouldn't start with these if the problem is really bad, but the closer you get back to normal, the more important they become. ⬩Antimicrobial/anti-biofilm effects ⬩Essential for gut immunity ⬩Enhance gut motility ⬩Can metabolize food components

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There are a few key types of probiotics: 1. Lacto/Bifido blends 2. S. Boulardii 3. Spore based probiotics There are more, and each has shown effectiveness in their own right.

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The keys to success using probiotics seem to be: 1. Using multiple strains / types 2. Consistency & duration - 2 months is a good starting point 3. Taking with antimicrobials - counterintuitive but works better Fermented foods can also be good.

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GUT MOTILITY is VITAL for fixing digestion. If you don't: ⬩Greater bacterial fermentation ⬩More inflammation from food lingering ⬩More gas production, retention (bloating) Some hallmarks of gut problems are slowed motility & greater fecal mass.

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Some tools to enhance gut motility: ⬩Coffee⬩Cascara⬩Triphala⬩Raw carrot⬩Mushrooms⬩Mastic gum⬩ More on mastic here:

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A POWERFUL DIGESTIVE HEALING TOOL EVEN FOR IBS AND IBDs! MASTIC GUM: HOW IT PROTECTS THE GUT! THREAD

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A HUGELY underrated & important factor for gut health (specifically motility) is the circadian rhythm. This controls the gut’s immune system, motility, enzyme secretion, and more. People with disrupted rhythm’s are at around double the risk of getting IBS.

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KEYS to a robust circadian rhythm for optimal gut health: ⬩Consistent sleep / wake times ⬩Sunlight exposure to the eyes (especially early morning) More on that here:

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You WILL NOT have good digestion… without addressing this first. The key to relieving your indigestion, constipation, and bloating may be where you least expect it. Let’s talk about it:

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Gut motility is largely governed by the vagus nerve - the main nerve of the "rest and digest" system. The primary neurotransmitter of the vagus nerve is acetylcholine, and its synthesis is supported by: • Choline • B1 • B2 • B5 • B9 • B12 • Glycine • Creatine •

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Other ways to support the vagus nerve: ⬩Pregnenolone⬩Progesterone⬩Carnosine⬩Butyrate⬩Humming⬩Acupressure points⬩Breathing practices⬩Sunlight⬩Maintaining circadian rhythm⬩Grounding⬩ More on grounding here:

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The best thing you can do for your health that no one is talking about. You’ll be sleeping like a baby, reducing your stress, and crushing inflammation. Literally touch grass. Why GROUNDING is the missing link to your optimal health:

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Near complete resolution of inflammation within an hour of grounding. Literally just by putting your feet on the earth (grass or soil).

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STRESS will destroy digestion. ⬩Worsens gut immunity - allowing for dysbiosis ⬩Slows motility (but can also cause diarrhea) ⬩Impairs energy production ⬩Directly drives inflammation More on that here:

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Stress DESTROYS your gut more than anything. 1. During stress, CRH is released from the brain. This hormone travels to the gut, and directly causes: • "Leaky gut" - which exposes bacteria / food components to the body, driving inflammation. • Serotonin release - a primary mediator of symptoms like bloating, sensitivity, lack of appetite, etc. Carbohydrate, pregnenolone & progesterone are tools to help lower the release of CRH. 2. Stress worsens immunity. Chronic stress: • Depletes sIgA, an antibody in the gut that prevents adhesion & inflammation • Shrinks the thymus gland, a primary immune organ where immune cells develop. • Directly suppresses & kills immune cells This all leaves us susceptible to pathogenic bacterial overgrowth, which: • Produce gas, leading to pain & bloating • Drive serotonin production Vitamins A, D, C, and zinc are the primary nutrients for supporting immunity. 3. Stress weakens digestion Stress has been shown to lower the production of: • Digestive enzyme • Stomach acid • Bile acid All of which are obviously vital for actually breaking down & absorbing the food. Stress ALSO screws up motility. The vagus nerve is one of the primary parasympathetic or "rest & digest" nerves in the body. One of its primary functions is to support the proper contractions of the digestive system. This ensures that the food gets moved along properly to prevent physical irritation. It also ensures that food doesn't stick around long enough to get overly fermented by bacteria. Digestive enzymes can be directly supplemented, stomach acid can be aided with Betaine HCl, and Bile acids can be supported with taurine / glycine or TUDCA. 4. Stress increases estrogen Cortisol is known to increase the conversion of androgens into estrogens via the aromatase enzyme. Women are more susceptible to conditions like IBS, especially during points in the cycle with higher estrogen to progesterone ratio. Androgens, especially DHT, have been shown to protect against the sensitivity & pain in the gut, while estrogen causes it. Estrogen ALSO up-regulates serotonin production, by causing the degranulation of immune cells called mast cells. These cells also produce histamine and other proteases that can lead to symptoms. Tools to lower / oppose estrogen: ‣ Saturated fat ‣ Vitamin A ‣ Vitamin D ‣ Vitamin E ‣ Progesterone ‣ Aspirin ‣ Vitamin B2 ‣ White button mushrooms ‣ Insoluble fiber (raw carrot) ‣ Naringin, naringenin, apigenin (citrus fruits)

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SEROTONIN (the "happy hormone") is the PRIMARY cause of digestive problems. Here's how (and what to do it about it): Bloating, gas, pain, diarrhea, constipation, general discomfort, sensitivity, histamine problems can ALL be directly caused by serotonin. Like serotonin acts

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Deficiencies of pretty much any nutrient can cause stress, but the most noteworthy anti-stress nutrients IMO are: ⬩Magnesium⬩Vitamin D⬩Carbohydrate⬩Salt⬩Potassium⬩Vitamin C Vitamin D specifically is often low in IBS, and supplementing is therapeutic.

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Excess estrogen can also wreck gut function. Women are more susceptible to IBS, especially during points in the cycle with higher estrogen ratio. Androgens, especially DHT, have been shown to protect against the sensitivity & pain in the gut, while estrogen causes it.

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Estrogen ALSO causes the degranulation of immune cells called mast cells. These cells also produce histamine and other proteases that can lead to symptoms. The levels of these cells are elevated in conditions like IBS. More on histamine here:

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If you have chronic bloating and gut pain, this is for you. This is A KEY culprit wreaking havoc on your gut that your doctor won’t even think about. Here’s how it’s tearing up your insides (and what to do about it):

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YOU MUST ADDRESS THIS TO FIX YOUR GUT This “happy hormone” is the primary driver of digestive problems. I found that out the hard way. Here’s what I’ve learned, how I lowered it and how you can do the same:

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Tools to lower / oppose estrogen: ⬩ Saturated fat ⬩ Vitamin A ⬩ Vitamin D ⬩ Vitamin E ⬩ Progesterone (most important)⬩ Aspirin ⬩ Vitamin B2 ⬩ White button mushrooms ⬩ Insoluble fiber (raw carrot) ⬩ Naringin, naringenin, apigenin (citrus fruits) ⬩Calcium D-Glucarate⬩

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If your metabolism sucks, good luck digesting anything. You need energy for: ⬩Stomach acid⬩Digestive enzyme secretion⬩Motility⬩Immunity⬩Maintaining bacterial balance⬩ The gut is extremely energy demanding.

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Some keys to enhancing energy production: ⬩Thyroid optimization / supplementation⬩B vitamins⬩Copper⬩Limiting polyunsaturated fats This is only scratching the surface, but thyroid health seems to be a low hanging fruit for many.

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The ultimate supplement to boost your metabolism: THYROID HORMONE - A complete guide 1. Symptoms you may be hypothyroid Just to name a few: • ALWAYS being tired • Feeling COLD, especially at the extremities • Slow / lethargic speech • Stubborn weight gain • Poor mood • Puffy features: cheeks, love handles, general water retention • Gynecomastia (man boobs) • Muscular weakness • Dry skin and hair • Anxiety • Hair loss • Always being sick Digestion is particularly responsive to thyroid hormone. • Constipation or diarrhea • Nausea • Bacterial overgrowth • Reflux are all common in hypothyroidism. Thyroid hormone is: ⬨ Key for gut regeneration, healing ⬨ Pro-motility ⬨ Vital for producing digestive enzymes ⬨ Required for producing stomach acid ⬨ Critical for gut immunity, gut barrier 2. Why labs are often misleading TSH is the primary (and often only) metric a doctor will test for hypothyroidism. A lower TSH should be indicative of higher thyroid hormone secretion, but it doesn't tell the full story. For starters, TSH can be lowered by: • Infection • Trauma • Cortisol • Adrenaline • Caffeine • Fever So a low TSH alone cannot rule out hypothyroidism. The standard TSH reference range is also WAY too lenient (up to 5). TSH >2 has been associated with: • Heart disease • High cortisol Thyroid hormones: • T4 (inactive) • T3 (active, pro-metabolic) • Reverse T3 (anti-metabolic) can also be measured in the blood, but this doesn't tell the full story either. These hormones must be transported through the blood, enter their target cells, and attach to the specific proteins in the cells that facilitate their actions. Not as simple as thyroid in blood = thyroid activity. Values of the “free” T3 and T4 can be misleading as well. Thyroid hormones do not need to be "free" to exert their effects on various tissues, contrary the current medical dogma. I still think testing can often be helpful, but you can certainly be hypothyroid while your labs look good on paper. 3. Diagnostics An underarm temperature measured first thing in the morning, leaving the thermometer under the arm for 10 minutes to equilibrate, should start be >97.8°F. Lower temperatures are highly indicative of hypothyroidism. This was the gold standard thyroid test (along with aforementioned symptoms) that was successfully used to treat thousands of hypothyroid people before blood tests. You can have “ideal” thyroid lab values yet be at the temperature of a hibernating bear. A healthy resting pulse averaged 85 beats per minute, though Dr. Ward Dean has suggested between 65-75 is a good range. If you eat carbs can and feel more tired and have lower temperature and pulse rate, this indicates a reliance on the stress hormones and a lack of thyroid function. The response of the Achilles tendon when tapped was another assessment tool. In a well-functioning thyroid, the foot would swing back energetically due to quick muscle relaxation. but a slow, controlled return motion indicated potentially sluggish energy status, often a sign of hypothyroidism. High cholesterol is another sign of hypothyroidism, while thyroid supplementation normalizes it. 4. NOT supplementing thyroid is unnatural Consuming thyroid gland is as natural and "ancestral" as it gets. Paleo researchers have stated that we probably consumed lots of thyroid gland throughout human history: "the shift from scavenging towards hunting... would have increased thyroid gland consumption by hominins and thereby exogenous thyroid exposure." "these Homo forebears started consuming small animals, such as amphibians, birds, and reptiles. This prey was consumed whole, and the animals’ thyroid glands thus provided a significant amount of thyroid hormone to their hominid predators." "Nevertheless, tissues and organs (including thyroid glands) are commonly consumed by the primary hunters" In fact, thyroid gland used to be in common foods like ground beef up until the mid 80s. It is only recently when we stopped eating the whole animal, including the thyroid gland! 5. Using natural desiccated thyroid (NDT) Desiccated thyroid comes from the thyroid glands of pigs or cows, and is the traditional way of supplanting thyroid hormones. A grain (60 mg) is the unit of measurement for supplementation, containing ~40 mcg T4 + ~10 mcg T3. A starting dose of a half grain is reasonable, and should be continued for 2-4 weeks before adjusting. The hormones take around this long to stabilize. As you use NDT, you should consistently track: 1. Morning temperature 2. Symptoms Once you get to >97.8°F and symptoms resolve, the correct dose has been found. The brand matters a lot. Many products seem to be unreliable, or outright useless. That’s definitely been my experience. I’ve tried numerous products over the last few years. I'll link below the thyroid product I have been using recently for myself and with clients. I would take it with food to slow the absorption, or even split into multiple doses with meals. I prefer at dinner. While some may require full replacement (4 to 5 grains), others find relief with as little as 15 mg (quarter grain). Broda Barnes observed that his patients often required about two grains of thyroid to alleviate hypothyroid symptoms, occasionally needing more. If you experience • Too fast of a heart rate • Palpitations, • Anxiety, • Overheating • Fatigue • Shaky feelings then you might have taken too much thyroid. The amount taken should be reduced or discontinued entirely. Effects of over stimulation should resolve in a few hours. This type of response can also indicate low cholesterol or an issue with liver function, two systems that the thyroid depends on to do its good. You may also need more nutrients, as the increased metabolic rate demands more resources. Eat your liver, egg yolks, and oysters. Many people who should be candidates for supplementation find that thyroid does nothing for them, no matter how much they take. In my experience, this always seems to be tied to an issue with the gut. I would try to address this first. Or, you just may not need it at all. You may need to address other factors. Of course, supplementing thyroid is not the ONLY way to improve thyroid function, but it seems like an appropriate strategy when other factors have been addressed.

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Something NOBODY talks about but is important to consider is SEROTONIN. You WILL have excess gut serotonin if you have these issues. It directly drives: ⬩Nausea⬩Pain⬩Sensitivity⬩Diarrhea⬩Bloating⬩Loss of appetite⬩ and more.

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Serotonin is primarily the result of dysbiosis and gut irritation. Some tools that can directly lower serotonin: ⬩Ginger⬩Lysine⬩Vitamins A & D⬩Zinc⬩Cyproheptadine⬩Benadryl⬩Zofran (Ondansetron)⬩Famotidine⬩ A deep dive on gut serotonin here:

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YOU MUST ADDRESS THIS TO FIX YOUR GUT This “happy hormone” is the primary driver of digestive problems. I found that out the hard way. Here’s what I’ve learned, how I lowered it and how you can do the same:

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INFLAMMATION is what directly facilitates a lot of these symptoms. The breakdown of the intestinal barrier, or "leaky gut," is a common underlying theme in all digestive problems that drives inflammation.

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Everything mentioned above plays a key role in driving or managing inflammation and the intestinal barrier, but some good foods to directly target it: ⬩Gelatinous meats / bone broth (glycine + hydroxyproline)⬩Raw milk⬩Orange juice⬩

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The most incredible healing food on the planet has been BANNED. It is a godsend for digestion, prevents allergies, lowers inflammation and even improves cognition. Why RAW MILK is a superfood:

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Raw milk is disgusting. We live in a first world civilized society and people are actively choosing to consume milk riddled with E. coli and listeria. Pasteurization is not some evil sorcery. It just kills the dangerous bacteria you morons.

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LACTOFERRIN is a Godsend for gut issues. ⬨ Repairs gut barrier ⬨ Bolsters iron absorption (unabsorbed iron is a serious problem for the gut) ⬨ Antibacterial ⬨ Anti-diarrheal ⬨ Anti-nausea ⬨ Reduces abdominal pain ⬨ More on lactoferrin below.

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LACTOFERRIN: A “miracle” supplement for your gut. 1. Lactoferrin is a powerful gut anti-inflammatory Lactoferrin was known to prevent and even cure cancer in the digestive tract of animals. A research group decided to apply this in humans. Patients given 3 grams of lactoferrin had their colon tumors slow in growth significantly. A 22 year old young man with severe Crohn’s disease caught wind of these results. He just moved to the United States and had lost access to the hefty medications he was on. He decided to try 1 gram of lactoferrin daily for himself. Cured. Lactoferrin at just 100 mg/day helped in Crohn’s disease, decreasing levels of the inflammatory markers IL-6 and hepcidin. One trial showed that 3 grams of lactoferrin per day resulted in 50% fewer incidences of diarrhea in just 2 weeks. 2. Any digestive symptom - lactoferrin can help Lower doses of lactoferrin are still a godsend for severe digestive symptoms. Another study showed lactoferrin at 600 mg daily diminished nausea, diarrhea and abdominal pain. One report of children who consumed lactoferrin at 100 mg / day showed a reduction in vomiting and gut inflammation. 3. Lactoferrin is antibacterial, antifungal and regulates iron Lactoferrin is critically important for its regulation of IRON. While iron is of course essential, it is a double edged sword. Unabsorbed free iron, which we are exposed to so much in today's food and in disease, directly causes inflammation and bacterial overgrowth in the gut. Lactoferrin is critical for chelating and ENHANCING intestinal absorption of iron. Lactoferrin acts as an iron transporter and thus REDUCES oxidative damage in the gut's nervous system. Think of iron literally rusting on your most vital tissues: lactoferrin is there to PREVENT this. It also boosts the expression of the famous BDNF in the gut, which allows the gut’s nervous system to regenerate properly. These gut based nerves are responsible for perceiving digestive symptoms, as well as numerous regulating motility which is impaired in digestive distress. But the ultimate root cause of these digestive conditions is typically bacterial. Lactoferrin has potent antibacterial effects, in part by binding with free iron. This deprives more pathogenic bacteria of this essential growth element, while actually providing iron to some commensal bacteria which have lower iron requirements. Lactoferrin also has direct antimicrobial properties by disrupting bacterial cell membranes. It also increases the activity of serine protease, and antimicrobial peptides like RegIII𝛾, enzymes which shred up bacteria. Lactoferrin has even been found to be effective against a variety of Candida species, an infamous fungus that causes gut and systemic infections in humans. 4. Lactoferrin heals the structure of the gut Lactoferrin is essential for both the creation and the differentiation of the intestinal epithelial into all of the cellular subtypes necessary to keep the gut functioning properly. Disruptions in the gut epithelial barrier can lead to antigens entering the area just underneath these cells, triggering the release of a variety of cytokines and contributing to intestinal inflammation. This is a phenomenon seen in EVERY digestive disease, and many other conditions seemingly unrelated to the gut. If you suffer from bloating, gut pain, loose stools or poor bowel habits, or issues like poor sleep, mood and skin problems, you can bet that this process is involved. HOWEVER, lactoferrin contributes to MAINTAINING the intestinal epithelial barrier and has immunomodulatory properties, which are both critical functions in protecting the gut mucosal immune system. Lactoferrin has been shown to support intestinal barrier integrity by upregulating tight junction protein expression and protecting the intestine from bacterial infections. I cannot stress enough how important this is. This is the most prevalent mechanism in any digestive condition you can think of, and lactoferrin can help prevent and heal it! 5. Lactoferrin calms the immune system Lactoferrin could be a viable solution to addressing lactose intolerance. It promotes the production of key digestive enzymes that break down lactose and sugar. If you seem to react poorly to a myriad of normal foods (skin reactions, loose stools, diarrhea, brain fog, etc), then lactoferrin could be the solution. We have various immune cells that are constantly sampling components of the gut to recognize the normal while weeding out pathogens. But this process can become impaired and our immune systems can become overactive, mounting unwarranted inflammatory responses, & driving tons of different digestive symptoms and intolerances to otherwise normal foods. However, lactoferrin influences immune cells to become more tolerant, and less inflammatory, preventing various gut symptoms. Essentially, it helps your immune system properly differentiate between what should and shouldn’t require inflammation. Secretory IgA is an immune component that serves a PIVOTAL role in gut health. It binds to pathogenic bacteria and other antigens from the environment and prevents them from causing inflammation. sIgA is known to get depleted during times of stress, and its absence tends to result in inflammatory problems in the gut. However, lactoferrin supplementation has been shown to INCREASE sIgA production in the gut, supporting our immunity and protecting us from bacterial overgrowths and infections that can wreak havoc on our gut health. Toll-like receptors (TLRs) are another critical mediator of intestinal inflammation, sensing various bacterial components in the gut like endotoxin. These receptors are elevated in the gut of people with IBS and inflammatory bowel diseases, yet lactoferrin has been shown to REDUCE their expression, leading to subsequent quelling of inflammation. 6. What is lactoferrin? Lactoferrin is a protein that is found mainly in MILK, at its highest concentrations in colostrum, the milk the mother produces when lactation first begins. This milk needs to be incredibly enriched in regenerative components for the offspring to survive and develop at this most crucial period. Bovine colostrum has been consumed for millennia for its God-like medicinal properties. Even Cleopatra was said to use it as it was seen as an immortal ingredient. 7. How to use it Therapeutic doses range from 100 mg up to 3 grams of lactoferrin daily. Makes sense to start at the lower end and gradually increase, though it is very safe so trying higher doses can be an option. Of course you can also get it from bovine milk (20-200 mg/L) or colostrum (2g/L), especially when raw, but the amount is variable and it can be tough to consume enough to hit the therapeutic targets. Human milk is even higher in lactoferrin, if you're really adventurous. I'll link the supplement we use with clients below, it's been such a key to our success!

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Another excellent tool is GLUTAMINE: ⬨ Improves small intestinal metabolism ⬨ Prevents dysbiosis ⬨ Anti-inflammatory ⬨ Repairs intestinal barrier ⬨ Improves abdominal pain / bloating /nbowel movements ⬨ A deep dive on using glutamine here:

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A cheap, easy and powerful tool for healing your gut. For bloating, distention, brain fog and more, the answer might just be GLUTAMINE. Here’s why, and how to use it for maximal digestive benefit:

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Sodium butyrate is another hidden gem for reducing gut inflammation. ◇ Supports gut energy production ◇ Anti-inflammatory ◇ Increases mucus production ◇ Increases antimicrobial peptides ◇ Increases gut motility ◇ Clinical benefit in IBD + IBS.

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Researchers have called it the guardian of the gut. It is a godsend for IBS, Crohn’s, Ulcerative Colitis and even colon cancer. Why BUTYRATE might be your key optimal digestion + gut health:

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There are tons of other supplements you can add to further support the gut. My point is not to take everything here at once, but to try to hit all angles for a comprehensive approach. Mix & match. Experiment. You will find a combo that works.

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Over the years, these tools have helped me and those I have worked with REVERSE digestive issues. 16 SUPPLEMENTS TO HELP HEAL YOUR GUT (and how to use them):

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Many of these principles & symptoms also apply to fungal overgrowths (like candida). Some antifungals that can help with candida: ⬨ Methylene Blue ⬨ Flowers of sulfur ⬨ Pau D'arco ⬨ Niacinamide ⬨ Aspirin ⬨ Oregano oil ⬨ Rosemary ⬨ S. Boulardii ⬨ Coconut oil ⬨ Raw honey ⬨ The pharmaceutical route (nystatin or fluconazole) can be effective here, too. One thing about fungal overgrowths is that they LOVE estrogen, they thrive on it. This is why fungal UTIs are common in women, especially pregnant women. Focusing on combating estrogen will be absolutely vital - see above. The prevailing notion is that carbs should be reduced during fungal overgrowth, though I don’t think this is true. Sure, carbs & sugars may serve as fuel for these organisms, but they also fuel our immune system’s capacity to get rid of excessive fungi.

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Parasites are also a noteworthy cause of gut issues. Signs you might have a parasite: • Digestive issues • Chronic fatigue • Skin issues • Muscle / joint pain • Anemia • Itchiness • Grinding teeth • Insomnia ESPECIALLY if these symptoms manifest more in the middle of the night (1-3 AM) Wormwood is a good natural option here. A short course of an antiparasitic like albendazole or ivermectin is also very low risk and effective for parasitic infections.

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All of these different variables interact. Inflammation drives gut dysbiosis + vice versa. Poor metabolism drives inflammation + vice versa. Dysbiosis will drive serotonin + vice versa. Poor motility will increase stress + vice versa. You need to focus on EVERYTHING to heal.

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Thank you for reading this, hopefully it was helpful. If it was, pls RT the first tweet here:

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READ THIS IF YOU WANT TO FIX YOUR GUT. If you have IBS, bloating, gas, poor bowel movements or brain fog, you NEED to see this. This is a comprehensive DEEP dive into fixing your digestive health:

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If you want personalized help from us with your gut or any other health goals, click where it says “schedule a free call” here: http://prism.miami

Prism Health The solution is out there. We can help you find it. prism.miami

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Posted - May 20, 2023 at 3:48 PM

Saved - June 23, 2025 at 12:28 AM

reSee.it AI Summary

Dopamine is often misunderstood as merely a source of pleasure, but its true role is in motivation, euphoria, and reward, which are essential for a fulfilling life. Many believe that lowering dopamine can help with addiction, but the issue lies in baseline dopamine levels. Addiction stems from a lack of reward in daily life, not excess dopamine. Factors like stress and serotonin inhibit dopamine synthesis, while proper nutrition can support its production. Ultimately, enhancing dopamine levels is crucial for health and well-being, not something to avoid.

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The TRUTH about Dopamine: It’s (actual) role in addiction, why it’s GOOD for you, and how to increase it. A thread

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“Cheap dopamine” and “dopamine hit” have become buzzwords in the health space, making it seem like dopamine exists to give you mindless pleasure, and that you need to lower dopamine to break addiction and achieve your goals. In reality, nothing could be further from the truth.

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Dopamine’s real role is in motivation, euphoria, and of course reward. I think this is the fundamental issue: we’ve been conditioned to believe that anything that makes you feel good is bad, a complete subversion of reality in my view.

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Euphoria, reward and motivation are all critical aspects to having a good quality of life, and are markers of health. Loss of pleasure in life means things are going downhill. Quality of life is one of the best predictors of health and longevity. https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-020-09639-9

Quality of life and mortality in the general population: a systematic review and meta-analysis - BMC Public Health Quality of life (QoL) is multi-dimensional concept of an individual’ general well-being status in relation to their value, environment, cultural and social context in which they live. This study aimed to quantitatively synthesise available evidence on the association between QoL and mortality in the general population. An electronic search was conducted using three bibliographic databases, MEDLINE, EMBASE and PsycINFO. Inclusion criteria were studies that assessed QoL using standardized tools and examined mortality risk in a non-patient population. Qualitative data synthesis and meta-analyses using a random-effects model were performed. Of 4184 articles identified, 47 were eligible for inclusion, involving approximately 1,200,000 participants. Studies were highly heterogeneous in terms of QoL measures, population characteristics and data analysis. In total, 43 studies (91.5%) reported that better QoL was associated with lower mortality risk. The results of four meta-analyses indicated that higher health-related QoL (HRQoL) is associated with lower mortality risk, which was consistent for overall HRQoL (HR 0.633, 95% CI: 0.514 to 0.780), physical function (HR 0.987, 95% CI: 0.982 to 0.992), physical component score (OR 0.950, 95% CI: 0.935 to 0.965), and mental component score (OR 0.980, 95% CI: 0.969 to 0.992). These findings provide evidence that better QoL/HRQoL was associated with lower mortality risk. The utility of these measures in predicting mortality risk indicates that they should be considered further as potential screening tools in general clinical practice, beyond the traditional objective measures such as body mass index and the results of laboratory tests. bmcpublichealth.biomedcentral.com

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So why do people think dopamine is a problem? It comes down to your baseline levels.

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Issues in baseline dopamine function are a common occurrence in addiction. As Dr. Peat has described, I think addiction is simply the body trying to adapt to this suboptimal condition, seeking [often suboptimal] dopaminergic activities.

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Dopamine agonists or precursors can treat various addiction states, likely because the body perceives existing baseline pleasure in life. It’s not the dopamine that makes you addicted, it’s the lack of reward you get with your everyday life.

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This is demonstrated further with the rat park studies, which found near complete withdrawal from morphine when the rats were taken out of their boring desolate cages and given free reign in a more stimulating environment.

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Whatever your vice of choice is, I can guarantee it’s a lot harder to give up when you’re forced into meaningless work or boring environments. It’s no wonder dopamine gets a bad name. We don’t get it the way we should: with a stimulating life. We may as well be rats in cages!

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Dopamine synthesis tends to be inhibited by components of the stress system. Notably serotonin, which promotes estrogen which in promotes a hormone called prolactin. This cascade can produce a numbing or anhedonic effect on mood, the opposite of dopamine.

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Conversely, dopamine is one of our primary protectors against these: it inhibits TPH (serotonin synthesis), aromatase (estrogen) and prolactin synthesis. These play huge roles in conditions from IBS to infertility and even cancer, and DOPAMINE is what keeps them in check.

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It should be no wonder a lack of dopaminergic function is a huge factor in several serious diseases like depression, Parkinson’s and Alzheimer’s. Sexual function, coordinated movement and even proper vision are highly dependent on dopamine being high.

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Modern medicine already knows the value of dopamine! Dopaminergic drugs and precursors are used in many of the conditions mentioned previously. Unfortunately the most commonly used one, amphetamine or adderall, is highly excitatory and stimulates the stress response.

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This does bring up an important point, which is dopamine’s relation to the other catecholamines, adrenaline and noradrenaline. Dopamine is a precursor to these “fight or flight” mediators, which produce jitters, high blood pressure and general discomfort or anxiety.

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This is probably another reason why people think dopamine is not good. However, more dopamine does not necessarily mean more stress catecholamines. In other words, you’d want to nourish and stimulate your synthesis of dopamine in a stress reducing manner.

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Dopamine synthesis depends on the amino acid l-tyrosine (or phenylalanine), heme iron, vitamin B6 and indirectly vitamin B9 and vitamin C. Eating enough food and especially carbohydrate is paramount for keeping the downstream stress mediators low.

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One of the cofactors necessary for dopamine synthesis also needs to be recycled through the antioxidant-linked pathway. Eating enough carbohydrate, vitamin E, glycine, and vitamin B3 are some important nutrients here.

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Lowering serotonin is also key, since it is a primary inhibitor of dopamine synthesis. Gut function is crucial here, since the vast majority of serotonin is produced there. Vitamin D is a TPH inhibitor, and there are a number of anti-serotonin drugs (NOT MEDICAL ADVICE)

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I would caution against using the precursor L-Dopa, which can rapidly convert into dopamine, but also catecholamines through providing massive amounts of substrate. It's associated with some nasty side effects. Meanwhile, targeting the nutrients shouldn’t cause excess adrenaline

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Of course, there are also dopaminergic supplements and drugs. Personally, some of my favorites are methylene blue, caffeine (coffee), adamantane and pregnenolone and progesterone.

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We are blessed to have partnerships with the highest quality supplement providers for methylene blue, and now pregnenolone and progesterone too! Be sure to check out this link for discounts! https://lnk.bio/analyze.and.optimize

Analyze & Optimize Analyze & Optimize - Content, Consultations & Affiliate Links lnk.bio

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All in all, dopamine is not something you need to fast from, it’s not causing your addiction, and it certainly isn’t preventing you from where you wanna be. If anything, an approach to improve basal dopamine levels is key to an optimal life and disease prevention.

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If you enjoyed this thread sauce us a RT, and be sure to check out our other content, supplements, socials and ways to ask questions through https://lnk.bio/analyze.and.optimize

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I discuss the topic in greater detail here! https://youtu.be/xELyqRIPMPk

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Posted - June 18, 2025 at 3:00 PM

Saved - June 22, 2025 at 6:07 PM

reSee.it AI Summary

I've been exploring the incredible health benefits of coffee, which seems to be a powerful ally in promoting longevity. Studies show that drinking coffee can significantly reduce the risk of death and various diseases, including cancer and diabetes. It enhances molecular markers of aging, improves mitochondrial function, and even supports cognitive health. Coffee's bioactive compounds, like chlorogenic acids, play a crucial role in these benefits. However, it's important to choose toxin-free coffee for the best results. Overall, coffee is a remarkable tool for health and longevity.

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The greatest longevity hack of all time has been sitting your cabinet and costs you next to nothing. Coffee literally checks every single box for being an anti-aging wonder medicine, but no one is talking about it:

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Coffee powerfully lengthens lifespan. Here, 6+ cups of coffee associated with >50% reduced risk of death. Most studies show that coffee consumption reduces risk of all cause mortality by 20%+. Here they found a LINEAR decrease in death - the more coffee, the lower risk.

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Drinking coffee prevents risk of death from sedentary lifestyle. People sitting >6 hr/day ➡️ increased mortality but NOT if they drank coffee. People who are active + don't drink coffee were as likely to die as inactive coffee drinkers. But how is coffee able to do this?⬇️

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Coffee improves literally EVERY molecular biomarker of aging in existence. For instance, it increases sirtuins. These "longevity proteins" control genes that: ➞ Reduce inflammation ➞ Increase antioxidant support ➞ Support metabolism / mitochondrial function

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Coffee intake might lengthen telomeres. Telomeres are protective proteins on the ends of genetic material, but their length tends to decline with age. As such, it's considered a classic hallmark of the aging process. Once again, we see that coffee consumption is protective.

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Coffee's bioactive compounds act on nearly every "longevity pathway" in the book. Increasing: ➜ PPARα - turns on fat burning genes ➜ Mitochondrial membrane potential (energy capacity) ➜ NRF2 - a master antioxidant signaling protein ➜ SOD, CAT - antioxidant enzymes

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It doesn't end there, as coffee was also shown to increase: ➜ AMPK ➜ PGC1a ➜ Oxidative phosphorylation / ATP - mitochondrial energy ➜ Metabolic enzymes - CS, GK, ➜ IRS1 (insulin signaling) Every one of these declines with age and are huge focuses in longevity research.

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Coffee compounds suppress mTOR, another major "aging pathway." Much of the magic of coffee lies in its chlorogenic acids. Apparently, they can inhibit mTOR - a protein complex involved in growth. Inhibiting mTOR is one of the longevity sector's primary goals.

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One of the hallmarks of aging is worsened mitochondrial function & slower metabolism. The chlorogenic acids in coffee up-regulate nearly EVERY enzyme in the mitochondrial energy generation process. This is BEYOND being a stimulant, coffee is legit metabolism enhancement.

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Coffee improves epigenetic age. These "clocks" are used to estimate biological aging based on modifications to DNA. This is another major focus of longevity researchers. Coffee helps.

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4+ cups of coffee is associated with the best biomarkers across the board. Higher: ◇ Testosterone ◇ Free Testosterone ◇ Adiponectin Lower: ◇ IL-6 (inflammation) ◇ CRP (same) ◇ Insulin ◇ Estrogen ◇ Leptin The more coffee drank, the better these markers were.

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Coffee prevents oxidative damage. The most widely known theory of aging is the free radical theory, which states that oxidative damage from free radicals drives aging by messing up cell signaling and physically destroying structure. Coffee has been shown to mitigate this.

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Coffee also inhibits iron absorption. Iron excess is a part of aging as well, as it can accumulate in tissues and drive oxidative damage to our tissues. It literally rusts you from the inside. Coffee prevents it. More on that below.

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Bloodletting was awesome, actually. I’m serious. Modern research has proved it time and time again. BLOOD DONATION - the science, benefits, and how to know if you might benefit:

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3 cups of coffee lowers risk of liver cancer by 90%. Known as the magical bean for liver disease, coffee's: ◇ Caffeine ◇ Diterpenes ◇ Chlorogenic acids are unique molecular anti-inflammatory / antioxidant factors that have anti-cancer & liver protective effects.

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Up to 6 cups of coffee a day cuts down the risk of dying from ANY cancer. Specifically, coffee is extraordinarily protective against colon cancer. Coffee actually has multiple benefits for the gut, due to its anti-inflammatory compounds.

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Coffee drops risk of inflammatory bowel disease by 60%. It actually reverses leaky gut - a core process in all gut issues. ◇ Increases tight junction proteins ◇ Reduces endotoxin levels ◇ Lowers gut inflammation (nitric oxide) Its phenolics positively modify gut bacteria.

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6+ cups of coffee a day cuts suicide risk by 80%. Repeatedly shown that coffee has antidepressant and health promoting properties. Coffee drinkers are happier.

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6+ cups a day drops the risk of developing diabetes by nearly 40%. Experiments show that drinking coffee consistently improves insulin sensitivity.

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Coffee also prevents cognitive decline. Its components have been shown to prevent the protein aggregation - a key player in Alzheimer's. They inhibit the aggregation and seeding of tau proteins, which contribute to a slew of neurodegenerative processes in the brain.

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Tau proteins are also a key player. These are proteins that wrap around structural proteins called microtubules. They can become detached and drive all sorts of problems: ↦ Drive inflammation ↦ Cause oxidative stress ↦ Directly neurotoxic Tau proteins actually induce chain reactions where they promote their own production, too. This is probably why Alzheimer's is a progressive condition in most instances. But again, we are left asking how we can: 1. Reduce harmful tau hyperphosphorylation to begin with 2. Reduce its toxicity of it does get formed

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The magic in coffee lies in its bioactives - researchers have literally called it "an Elixir of Youth." Caffeine has tons of benefits which I've covered in the thread below. ➞ Chlorogenic acids ➞ Caffeic acid ➞ Melanoidins ➞ Diterpenes ➞ Trigonelline ALL have independent, additional benefits. Some can act as direct scavengers for free radicals, others can act as inhibitors for some of the primary inflammatory pathways, like TLR4 / NF-κB. For many, coffee is THE MOST abundant + important source of these compounds - so it's no wonder it's constantly linked to better lifespan and disease risk.

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Coffee is an incredible tool for your health, but it's also commonly contaminated with mold + pesticides. Thankfully, our friend @AlpacaAurelius has produced an awesome toxin free coffee here, which we've been using. https://carnivoreaurelius.com/products/organic-clean-coffee

Pesticide & Mycotoxin Free Roasted Coffee Grass-fed and finished, nutrient-dense supplements and snacks to optimize your health. carnivoreaurelius.com

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While coffee is great, unlocking the best health possible will be a journey. If you want PERSONALIZED, IN DEPTH help from us with any of your health goals, schedule a free call here: https://www.prism.miami/scheduling

Booking — Prism Health prism.miami

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Thank you for reading through this. Give this tweet below a repost if you found it interesting to spread the message.

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The greatest longevity hack of all time has been sitting your cabinet and costs you next to nothing. Coffee literally checks every single box for being an anti-aging wonder medicine, but no one is talking about it:

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Be sure to check out all of our content, supplements, lab testing options and join our email list for exclusive offers here: http://www.analyzeandoptimize.io

Analyze & Optimize | enhanced existence Restoring youth through bioenergetics. Esoteric health information from Analyze & Optimize. analyzeandoptimize.io

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Posted - June 12, 2025 at 1:00 PM

Saved - June 12, 2025 at 11:49 PM

reSee.it AI Summary

I shared five warning signs that your health might be deteriorating, which many consider normal. Cavities can indicate microbiome imbalances, while greying hair often results from stress and nutrient deficiencies. Pimples reflect deeper health issues like high insulin and gut dysbiosis. Chapped lips may stem from nutrient deficits and hypothyroidism, and dark circles under the eyes signal collagen loss and oxidative stress. It's important to address these signs early, and I offer support for those seeking to improve their health.

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5 warning signs your health is deteriorating, but you think are normal: #1 Cavities This is often a sign of microbiome imbalances. Cavities are driven by acidity from bacteria, which degrades the enamel of the teeth. Bad bacteria in the gut = bad bacteria in the mouth.

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Nutrients are also vital for remineralizing the teeth. Teeth are not rocks. They're tissues that remodel actively. Your body needs: ➥ Vitamin D ➥ Calcium ➥ Vitamin K2 ➥ Vitamin A in order to remineralize properly. More on that below.

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What your dentist won’t tell you to prevent cavities, bad breath, gum disease and have straight teeth. The 8 MOST IMPORTANT NUTRIENTS for DENTAL health (plus why and how to get enough of each):

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#2 Greying hair This is a primary sign of stress. The melanocytes that produce the coloring pigment melanin for your hair strands can die off if they're exposed to high levels of stress hormones.

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The process of creating melanin starts with the dietary amino acid TYROSINE. The conversion of tyrosine into the forms of melanin requires: ➡ Tyrosine ➡ Copper ➡ Zinc ➡ Iron ➡ Vitamin C ➡ Vitamin B9 If you are low on ANY of these, you are likely to get grey hair.

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Hypothyroidism grays hair - thyroid hormones reverse it. Preserving melanocytes (+ their stem cells), along with copper utilization requires lots of ENERGY. Thyroid hormone can restore melanin production.

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If you have grey hair, you're under oxidative stress. This is the process where production of harmful reactive oxygen species outpaces our antioxidant support, and is the principle cause behind aging and essentially any disease you can think of.

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#3 Pimples Even if they're painless, pimples are a result of a slew of deeper rooted health issues: ➞ High insulin / IGF-1 ➞ Gut dysbiosis ➞ Oxidative stress ➞ Inflammation ➞ Nutrient deficiencies These synergize to promote a pimple primed skin environment.

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How pimples form: 1. Excessive sebum production (high insulin/IGF-1, inflammation) 2. Oxidation of sebum (poor antioxidant status) 3. Excess keratin production / accumulation (low vit A) 4. Mix of oxidized sebum + keratin = clogged pore 5. Bacterial infiltration + inflammation of clogged pore

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#4 Chapped lips Excessive water loss in the lips can be driven by these nutrient deficits: Vitamin B2 ➜ Maintains epithelial integrity Vitamin B6 ➜ Protein + lipid metabolism Zinc ➜ Skin repair, anti-inflammatory Vitamin A ➜ Regulates keratinization

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The lips are more vulnerable to becoming dry in comparison to other skin regions, which causes chapping. Hypothyroidism → slows skin turnover / oil production Chronic inflammation → impairs barrier repair at the lips + Dehydration all impact lips first.

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#5 Dark circles under eyes This can be a sign of: ➞ Systemic loss of collagen synthesis ➞ Poor vascular function ➞ High iron ➞ Oxidative stress

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How dark circles form: The skin underneath the eyes is very thin - more susceptible to collagen loss. Hemoglobin (from the blood) gets oxidized & accumulates in this area with blood vessel congestion and damage. Poor lymph mobility keeps it around when it should be drained.

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If you feel puffy, have “cortisol face,” are congested and feel like your body needs a reset, look no further. You’re probably filled up with fluid that won’t leave until you address this. Let’s talk about the LYMPH STAGNATION - why it is harmful & how to fix it:

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Having these signs isn't the end of the world, but if you do have any of them, it's best to act now before things get out of hand. If you'd like some help with that, we have an experienced team providing in depth support. Book a free call with us here: prism.miami/scheduling

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Thank you for reading through this. Give this tweet below a repost if you found it interesting to spread the message.

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5 warning signs your health is deteriorating, but you think are normal: #1 Cavities This is often a sign of microbiome imbalances. Cavities are driven by acidity from bacteria, which degrades the enamel of the teeth. Bad bacteria in the gut = bad bacteria in the mouth.

@Outdoctrination - Analyze & Optimize

Be sure to check out all of our content, supplements, lab testing options and join our email list for exclusive offers here: http://www.analyzeandoptimize.io

Analyze & Optimize | enhanced existence Restoring youth through bioenergetics. Esoteric health information from Analyze & Optimize. analyzeandoptimize.io

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Posted - November 16, 2024 at 5:29 PM

Saved - June 3, 2025 at 11:53 PM

reSee.it AI Summary

I’ve shared an extensive guide on stress, covering its signs, biological mechanisms, and solutions. Stress manifests in various symptoms, including sleep issues, anxiety, and digestive problems. I discussed the body's stress response, emphasizing the role of the hypothalamus and hormones like cortisol. Nutrients such as vitamins C, D, E, zinc, and magnesium can help lower stress levels, while lifestyle factors like sunlight exposure, grounding, and social interaction are crucial. I also highlighted the importance of managing inflammation and gut health in stress reduction.

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High cortisol, anxiety, and can’t sleep? This is for you. This is the ULTIMATE GUIDE to STRESS - the signs, the biological mechanisms and what to do about it:

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There are TONS of symptoms that you might not have realized are from stress. 1. Can’t fall asleep 2. Waking up in the night to pee 3. Waking up in the night for no reason 4. Nightmares / sleep paralysis 5. Foamy urine 6. Hair loss 7. Hair graying 8. Gain weight easily 9. Gaining weight in the abdomen (visceral fat) 10. Low appetite 11. Cold extremities (fingertips, nose, toes, ears) 12. Menstrual cramps 13. Irregular menstruation or premenstrual syndrome 14. Irritability 15. Anger or aggression 16. Twitching 17. Headaches 18. Itchiness 19. Jitters 20. Anxiety / fear 21. Lack of confidence 22. Insatiable appetite or sweet cravings 23. Trouble catching your breath or breathing heavily 24. Pounding heart 25. Constipation 26. Nausea 27. Diarrhea 28. Gut pain 29. Acid reflux 30. Frequent urination

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One of the simplest test for stress is the heartbeat / blood pressure. Feel your pulse - if it feels like there’s pressure / pounding, good sign your body is under stress. The pupil test is another easy way to tell (linked below)

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An easy at home test for chronic stress: In a dark room with a mirror. Shine flashlight (from the side) towards pupils and hold it for ~1 min. Healthy: pupils constrict and stay small. Chronic stress: pupil gets small but starts to enlarge again or obviously flutter.

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The body’s stress system: EVERYTHING originates in the brain - this is what allows us to perceive stress and mount a physiological response. The amygdala in the brain is where a lot of this perception happens, And the hypothalamus is the control center - coordinating the stress to other parts of the body. The hypothalamus: → Stimulates the pituitary (with a hormone called CRH), which then sends another hormone (ACTH) to the adrenal cortex to produce CORTISOL (among other hormones). This is known as the hypothalamus-pituitary-adrenal (HPA) axis, the primary stress system in the body. → Transmits signals to the brain stem and then to the spinal cord - which sends nerve fibers throughout the body → Some of these fibers connect to the adrenal medulla, which secretes adrenaline and noradrenaline There are tons of other stress hormones and signals, which we will get into, but ultimately they all work by or as a result of these core systems. It is perfectly designed to respond to external threats, where you SHOULD be stressed, But that’s not what we’re focused on. We are talking about excessive, chronic, inappropriate and/or overactive stress responses. How can we live calmly while not becoming numb to things that necessitate stress?

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A lack of glucose (carbohydrate) drives the stress response. The brain’s hypothalamus has cells that increase CRH in response to low glucose levels, which activates: 1. HPA axis (cortisol) 2. Sympathetic nervous system (adrenaline) Both of which stimulate the hormone glucagon as well. These hormones stimulate our body’s creation of glucose. This is why eating carbohydrate or sugar acutely lowers the stress cascade, and restriction of carbs promotes it.

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Calorie restriction is another stressor. There is a reason people “stress eat” - the stress systems are there to serve as backup when there’s not enough food. This doesn’t mean stuffing your face, it just means not intentionally restricting food intake.

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Other nutrients are also key for lowering stress. Vitamin C drastically lowers cortisol. 1,000 mg / day drops it by >35% after 2 months. Vitamin C is released by the adrenal glands and becomes depleted during stress. More on vitamin C linked below:

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VITAMIN C: ⇨ Anti-cancer ⇨ Lowers stress ⇨ Renews skin ⇨ Improves sex life ⇨ Enhances energy & motivation ⇨ Crushes anxiety ⇨ Reduces sickness & more. Let's talk about the benefits of it, how to get enough and supplementation. THREAD:

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Zinc dramatically lowers cortisol. A 50 mg zinc dose suppressed the stress hormone by around 70% here. While the HPA axis, which produces cortisol, depletes zinc, adding it back in markedly lowers this stress system. More reading on zinc linked below:

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It heals the gut & skin, reduces inflammation & fatigue, and massively boosts sexual health. That's just scratching the surface. The benefits of ZINC are nearly endless:

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Magnesium powerfully lowers lowers cortisol + IL-6 (inflammation). It acts as a calming mineral in the nervous system + brain. Stress also depletes magnesium, creating a vicious cycle. I've written a ton on magnesium linked below.

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There's a 3 in 4 chance you're low on this nutrient. It heals fatigue, anxiety, depression, sleep problems, even ADHD. This is ULTIMATE GUIDE to MAGNESIUM: its incredible benefits & how to get enough. THREAD

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Vitamin E reduces stress. 200 IU/day markedly improves blood pressure, which is governed by stress hormones. I've written tons about vitamin E linked below:

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The universal protector. For the poisons of the modern world, VITAMIN E is one of the best tools to maintain your health. Here's why:

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Vitamin D is also a potent anti-stress nutrient. 2,000 IU lowered cortisol by 40% here. Inflammation acts directly on the brain and adrenals to drive stress. These nutrients all help to lower inflammation. I've written a ton on vitamin D linked below:

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The FREE vitamin that NO ONE gets enough of. WAY beyond preventing colds, it enhances brain function, crushes stress and massively improves energy. Let's talk about the multifaceted benefits of VITAMIN D:

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Another stress hormone is parathyroid hormone. It increases with low dietary calcium and vitamin D. High PTH can lead to high calcium in the blood, which can be very stressful and even toxic to the nervous system. PTH increases other adrenal hormones, like cortisol.

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Restricting salt intake activates stress systems, too. This stress is called the renin-angiotensin-aldosterone system. The purpose of this system is to retain sodium, increasing the excretion of potassium and activating the stress systems of the nervous system.

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High salt diets are powerfully anti-stress. 1,150 milligrams vs 5175 mg of sodium, the higher salt amount cuts adrenaline in half. I’ve written in depth on the benefits of adequate salt for stress here:

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Salt has been demonized for the last 50 years, but eating more salt can lower stress, improve metabolic health and might even make you live longer. Here are the BENEFITS of SALT (Thread):

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SALT: Why it DOESN’T cause high blood pressure, and restricting it is silly. [Thread]

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Lifestyle is another foundation of stress reduction. Expose your eyes to BRIGHT light. This lowers cortisol throughout the day. Dim light causes it to stay elevated. Have written more on bright light here:

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The effects of BRIGHT LIGHT on your mood are more important than anyone realizes. If you’re feeling down, tired, stressed, or anxious, this may just be the answer you never knew you needed. I found that out the hard way. Here’s why:

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Sunlight in general is important. The UV light hitting your eyes causes the brain to secrete a hormone called αMSH, Which has anti inflammatory effects that stop the excessive activation of the HPA axis. Sunlight has also been shown to help lower blood pressure.

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Another important lifestyle factor for reducing stress is GROUNDING. Grounding: • Calms the sympathetic nervous system • Lowers inflammation • Lowers blood pressure • Lowers cortisol • I’ve written a ton on grounding here:

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The best thing you can do for your health that no one is talking about. You’ll be sleeping like a baby, reducing your stress, and crushing inflammation. Literally touch grass. Why GROUNDING is the missing link to your optimal health:

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Near complete resolution of inflammation within an hour of grounding. Literally just by putting your feet on the earth (grass or soil).

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The way you breathe governs your stress levels, too. Diaphragmatic breathing can dampen the sympathetic nervous system, while “chest” breathing stimulates it. More on that here:

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Lowering stress is essential to optimal health. Let’s talk about how to use your breathing to do so, and what this tells us about stress in general. [Thread]

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Simply being in nature is a great way to lower cortisol. Very underrated aspect of it all, as it is easy to get caught up in the biochemistry.

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Your environment is a major dictator of your stress levels. Taking animals from their bleak cages into an open environment with toys and such results in lower stress hormones. If your day to day life is boring and lacks stimulation, you’re probably going to be stressed.

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Social isolation is another good way to raise your stress hormones. Lowers dopamine, raises prolactin and cortisol. So go hang out with your friends. Don’t focus on lowering stress so much that you forget about actually living your life - it will always backfire.

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Another reason nature can lower stress is due to negative air ions. These are generated by things like waterfalls, fountains, forests and beaches. They have been shown to reduce sympathetic / adrenal tone. One major reason for this is that they reduce circulating serotonin.

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The gut is a major source of stress. It has sympathetic nerves lining it, transmitting stress signals to the CNS. The gut also is a major source of inflammation, serotonin, and estrogen - all of which drive stress. Master gut thread is linked below.

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READ THIS IF YOU WANT TO FIX YOUR GUT. If you have IBS, bloating, gas, poor bowel movements or brain fog, you NEED to see this. This is a comprehensive DEEP dive into fixing your digestive health:

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Serotonin is a stress hormone. It is released from the gut in response to bacterial overgrowth + irritation. Activates the hypothalamus, pituitary and adrenals to drive stress hormone production. I’ve written extensively on the serotonin x gut below.

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YOU MUST ADDRESS THIS TO FIX YOUR GUT This “happy hormone” is the primary driver of digestive problems. I found that out the hard way. Here’s what I’ve learned, how I lowered it and how you can do the same:

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Histamine is another stress factor. Excess histamine can come from the gut, and from mast cell activation. Tools to lower excess histamine: ◈ Vitamin C ◈ L-Carnosine ◈ Diamine oxidase ◈ L. Plantarum ◈ Ginger ◈ Progesterone ◈ Skullcap ◈ Quercetin ◈

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I’ve also written more about histamine linked below.

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If you have chronic bloating and gut pain, this is for you. This is A KEY culprit wreaking havoc on your gut that your doctor won’t even think about. Here’s how it’s tearing up your insides (and what to do about it):

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YOU MUST ADDRESS THIS TO FIX YOUR GUT This “happy hormone” is the primary driver of digestive problems. I found that out the hard way. Here’s what I’ve learned, how I lowered it and how you can do the same:

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Aspirin is actually a powerful anti-stress tool. Due to its ability to lower inflammation and improve mitochondrial function, aspirin can lower cortisol and estrogen. I’ve written a ton on aspirin linked below.

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Modern medicine’s greatest contribution to the health of mankind. It heals cancer, depression and is even a nootropic. And it’s safe and cheap to boot. Why ASPIRIN is so much more than a painkiller and a blood thinner:

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Other sources of inflammation are important to address, too. Any source of chronic inflammation can drive the stress systems, and vice versa. Common contributors to chronic inflammation would be: ◇ Seed oils ◇ Heavy metal accumulation ◇ Mold ◇ Oxidative stress ◇

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Excess estrogen is another promoter of stress. Acts on the hypothalamus, pituitary and adrenals, to promote the production of cortisol. Progesterone is the main hormone that opposes the stressful effects of estrogen. I’ve written about that below.

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Crushing anxiety and stress, raising IQ and even preventing cancer? Just some of the things that the incredible PROGESTERONE can do (even for guys). Here’s how:

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Prolactin also contributes to fatigue and stress. It reliably increases with chronic and acute stress and stimulates the production of cortisol. The primary break on prolactin secretion is DOPAMINE, which I have written all about below.

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If you want high energy, pleasure, motivation and vivid dreams, you want more DOPAMINE. Here is the FULL COMPREHENSIVE GUIDE on optimizing it with nutrition & lifestyle. (bookmark this one, it’s long):

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Another way prolactin gets secreted is by lactic acid. In fact, lactic acid itself is a powerful promoter of stress. Giving people lactic acid can literally give them panic attacks. Lactic acid can also cause elevations in adrenaline and cortisol.

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The primary nutrient in terms of lowering lactic acid would be vitamin B1 or thiamine. It’s not the only one, but it definitely is the most important. I’ve written loads on thiamine here:

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The quintessential metabolism maximizing nutrient. From crushing fatigue, improving digestion and even cancer support - VITAMIN B1 might just be what you need:

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There are some other supplements that can help acutely as well. L-Theanine completely stops cortisol response to stress, at 200 mg. It increases GABA, dopamine, glycine while lowering serotonin in the brain, all of which suppresses the HPA axis and thus cortisol release.

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Pregnenolone is also a powerful anti-stress supplement. It directly suppresses the hypothalamus’ initiation of the stress cascade, and even lowers the amygdala’s emotional stress response. One of my all time favorites. I’ve written about it more below.

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The body’s primary protector against any and all stress life can throw at you. Pregnenolone: what it is, how it works, and why adding it in as a supplement could be a game changer for you. [THREAD]

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GABA can also completely stop cortisol response to physiological stress. 25-50 mg orally. GABA is the primary anti-stress neurotransmitter in the brain. It's also found in foods like yogurt, cheese, mushrooms and tomatoes.

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Phosphatidylserine is another anti-stress nutrient. PS supplementation lowers: ⬩Cortisol⬩Prolactin⬩ACTH⬩ in response to stress. PS aids in intracellular signaling, neurotransmission, and receptor activation.

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Thank you for reading through this. Give this linked tweet a RT if you found it helpful to spread the wealth.

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High cortisol, anxiety, and can’t sleep? This is for you. This is the ULTIMATE GUIDE to STRESS - the signs, the biological mechanisms and what to do about it:

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& if you want further support managing stress or reaching any other health goal, we are here to help. Click where it says “schedule a free call” here: http://prism.miami

Prism Health The solution is out there. We can help you find it. prism.miami

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Posted - April 4, 2025 at 1:53 PM

Saved - May 14, 2025 at 8:14 AM

reSee.it AI Summary

I’ve been exploring the causes and potential solutions for grey hair, which isn’t just a sign of aging but can be influenced by various factors. Melanin production, which gives hair its color, relies on nutrients like tyrosine, copper, and vitamins. Low levels of these can lead to greying. Oxidative stress and inflammation also play significant roles. Supporting the body with antioxidants, managing stress, and ensuring proper thyroid function are crucial. Interestingly, some supplements and dietary changes may help reverse greying.

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GREY HAIR isn't inevitable, it's a sign of aging that you can prevent or even reverse. The science of what causes it, and what you might be able to do to about it:

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Hair is gets its color from MELANIN - a chemical pigment our bodies produce. No matter what your hair color is, some form of melanin is going to give it that color. The process of creating melanin starts with the dietary amino acid TYROSINE. The conversion of tyrosine into the forms of melanin requires: ➡ Tyrosine ➡ Copper ➡ Zinc ➡ Iron ➡ Vitamin C ➡ Vitamin B9 If you are low on ANY of these, you are likely to get grey hair.

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The synthesis of melanin shares a common pathway with the synthesis of dopamine in a lot of ways. I've written on how to optimize for dopamine synthesis below.

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If you want high energy, pleasure, motivation and vivid dreams, you want more DOPAMINE. Here is the FULL COMPREHENSIVE GUIDE on optimizing it with nutrition & lifestyle. (bookmark this one, it’s long):

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In fact, supplying L-DOPA can actually recolor hair. L-DOPA is an intermediate in dopamine (& melanin) synthesis, and can also be found in the legume Mucuna Pruriens naturally.

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Copper is low in people with grey hair. Likely due to copper's role in the enzyme tyrosinase, which helps produce melanin for hair color. Iron can actually be high in these cases, despite its deficiency also contributing to greying, which I will explain in a bit.

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The more grey the hair - the lower the copper, calcium and iron. This should be the absolute priority for prevention. Copper foods: chocolate, liver, oysters, shellfish Iron: red meat Calcium: dairy, fish bones The role of calcium is a bit ambiguous but grey hair is consistently associated with osteopenia - a bone condition.

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Another study showed that vitamin D is also often low in people with grey hair. Vitamin D: ◇ Supports differentiation of stem cells into melanin producing cells ◇ Anti-stress ◇ Anti-inflammatory These are super important for maintaining hair color.

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More on how vitamin D works, its benefits and how to get enough here:

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The FREE vitamin that NO ONE gets enough of. WAY beyond preventing colds, it enhances brain function, crushes stress and massively improves energy. Let's talk about the multifaceted benefits of VITAMIN D:

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HOW HAIR GREYS: The most common reason for grey hair is the depletion of the cells that produce melanin (melanocytes). Melanocytes and their stem cells can be killed or stop proliferating due to several factors, and focusing on these is the KEY 👇

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Grey hair can driven by hypothyroidism. Thyroid issues are common in people with premature greying. For more on thyroid support, see below.

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The key to unlocking your metabolism, mood, energy and gut health is sitting under your tongue being ignored by your doctor. This is the ULTIMATE AND COMPLETE GUIDE TO THYROID HEALTH so you can optimize it:

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Hypothyroidism grays hair - thyroid hormones reverse it. Preserving melanocytes (+ their stem cells), along with copper utilization requires lots of ENERGY. Thyroid hormone can restore melanin production. For more on thyroid supplementation, see below

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The ultimate supplement to boost your metabolism: THYROID HORMONE - A complete guide 1. Symptoms you may be hypothyroid Just to name a few: • ALWAYS being tired • Feeling COLD, especially at the extremities • Slow / lethargic speech • Stubborn weight gain • Poor mood • Puffy features: cheeks, love handles, general water retention • Gynecomastia (man boobs) • Muscular weakness • Dry skin and hair • Anxiety • Hair loss • Always being sick Digestion is particularly responsive to thyroid hormone. • Constipation or diarrhea • Nausea • Bacterial overgrowth • Reflux are all common in hypothyroidism. Thyroid hormone is: ⬨ Key for gut regeneration, healing ⬨ Pro-motility ⬨ Vital for producing digestive enzymes ⬨ Required for producing stomach acid ⬨ Critical for gut immunity, gut barrier 2. Why labs are often misleading TSH is the primary (and often only) metric a doctor will test for hypothyroidism. A lower TSH should be indicative of higher thyroid hormone secretion, but it doesn't tell the full story. For starters, TSH can be lowered by: • Infection • Trauma • Cortisol • Adrenaline • Caffeine • Fever So a low TSH alone cannot rule out hypothyroidism. The standard TSH reference range is also WAY too lenient (up to 5). TSH >2 has been associated with: • Heart disease • High cortisol Thyroid hormones: • T4 (inactive) • T3 (active, pro-metabolic) • Reverse T3 (anti-metabolic) can also be measured in the blood, but this doesn't tell the full story either. These hormones must be transported through the blood, enter their target cells, and attach to the specific proteins in the cells that facilitate their actions. Not as simple as thyroid in blood = thyroid activity. Values of the “free” T3 and T4 can be misleading as well. Thyroid hormones do not need to be "free" to exert their effects on various tissues, contrary the current medical dogma. I still think testing can often be helpful, but you can certainly be hypothyroid while your labs look good on paper. 3. Diagnostics An underarm temperature measured first thing in the morning, leaving the thermometer under the arm for 10 minutes to equilibrate, should start be >97.8°F. Lower temperatures are highly indicative of hypothyroidism. This was the gold standard thyroid test (along with aforementioned symptoms) that was successfully used to treat thousands of hypothyroid people before blood tests. You can have “ideal” thyroid lab values yet be at the temperature of a hibernating bear. A healthy resting pulse averaged 85 beats per minute, though Dr. Ward Dean has suggested between 65-75 is a good range. If you eat carbs can and feel more tired and have lower temperature and pulse rate, this indicates a reliance on the stress hormones and a lack of thyroid function. The response of the Achilles tendon when tapped was another assessment tool. In a well-functioning thyroid, the foot would swing back energetically due to quick muscle relaxation. but a slow, controlled return motion indicated potentially sluggish energy status, often a sign of hypothyroidism. High cholesterol is another sign of hypothyroidism, while thyroid supplementation normalizes it. 4. NOT supplementing thyroid is unnatural Consuming thyroid gland is as natural and "ancestral" as it gets. Paleo researchers have stated that we probably consumed lots of thyroid gland throughout human history: "the shift from scavenging towards hunting... would have increased thyroid gland consumption by hominins and thereby exogenous thyroid exposure." "these Homo forebears started consuming small animals, such as amphibians, birds, and reptiles. This prey was consumed whole, and the animals’ thyroid glands thus provided a significant amount of thyroid hormone to their hominid predators." "Nevertheless, tissues and organs (including thyroid glands) are commonly consumed by the primary hunters" In fact, thyroid gland used to be in common foods like ground beef up until the mid 80s. It is only recently when we stopped eating the whole animal, including the thyroid gland! 5. Using natural desiccated thyroid (NDT) Desiccated thyroid comes from the thyroid glands of pigs or cows, and is the traditional way of supplanting thyroid hormones. A grain (60 mg) is the unit of measurement for supplementation, containing ~40 mcg T4 + ~10 mcg T3. A starting dose of a half grain is reasonable, and should be continued for 2-4 weeks before adjusting. The hormones take around this long to stabilize. As you use NDT, you should consistently track: 1. Morning temperature 2. Symptoms Once you get to >97.8°F and symptoms resolve, the correct dose has been found. The brand matters a lot. Many products seem to be unreliable, or outright useless. That’s definitely been my experience. I’ve tried numerous products over the last few years. I'll link below the thyroid product I have been using recently for myself and with clients. I would take it with food to slow the absorption, or even split into multiple doses with meals. I prefer at dinner. While some may require full replacement (4 to 5 grains), others find relief with as little as 15 mg (quarter grain). Broda Barnes observed that his patients often required about two grains of thyroid to alleviate hypothyroid symptoms, occasionally needing more. If you experience • Too fast of a heart rate • Palpitations, • Anxiety, • Overheating • Fatigue • Shaky feelings then you might have taken too much thyroid. The amount taken should be reduced or discontinued entirely. Effects of over stimulation should resolve in a few hours. This type of response can also indicate low cholesterol or an issue with liver function, two systems that the thyroid depends on to do its good. You may also need more nutrients, as the increased metabolic rate demands more resources. Eat your liver, egg yolks, and oysters. Many people who should be candidates for supplementation find that thyroid does nothing for them, no matter how much they take. In my experience, this always seems to be tied to an issue with the gut. I would try to address this first. Or, you just may not need it at all. You may need to address other factors. Of course, supplementing thyroid is not the ONLY way to improve thyroid function, but it seems like an appropriate strategy when other factors have been addressed.

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Grey hair is primarily driven by OXIDATIVE STRESS. This is the process where free radical production outpaces our antioxidant support. People with premature grey hair have higher markers of oxidative stress: ➮ High MDA ➮ Low glutathione ➮ Low superoxide dismutase

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The amount of oxidative stress is directly proportional to how bad the greying of the hair is.

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Grey hair follicles have poor antioxidant support. These follicles have worsened free radical scavenging activity - they are worse at preventing the oxidative stress that ultimately prevents pigmentation. They also have higher markers of DNA damage from oxidative stress.

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In fact, dropping hydrogen peroxide (which contributes to oxidative stress) on hair follicles can literally make the hair grey. This is in part due to the accumulation of methionine sulfoxide, which prevents pigment producing enzymes from working properly.

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Grey hairs have less antioxidant support. How can you support the antioxidant system? ☆ Vitamin E ☆ Vitamin C ☆ B1 ☆ B2 ☆ Selenium ☆ Copper ☆ Zinc ☆ NAc ☆ Glycine ☆ Taurine ☆ Red / near infrared / sun light ☆ Foods rich in these nutrients (liver, oysters, meat, gelatinous foods) ☆ Foods rich in flavonoids (fruits, whole juices, coffee, chocolate) ☆ Edible mushrooms (ergothioneine) ☆ Plenty of carbohydrates ☆ Avoid polyunsaturated fat (seed oils) like the plague

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High iron can actually contribute to oxidative stress, driving hair greying, while low iron can cause it from nutrient deficiency. Iron is a somewhat confusing double edged sword, but I've covered it (and the benefits of reducing it) more here

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Bloodletting was awesome, actually. I’m serious. Modern research has proved it time and time again. BLOOD DONATION - the science, benefits, and how to know if you might benefit:

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Antioxidants can reverse grey hair. Luteolin is a natural antioxidant found in fruits & vegetables like citrus, apples, carrots, onions etc. Both oral and topical administration or it re-colored the hair.

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Antioxidant blends reverse grey hair, regenerate melanocytes. This was using a topical lotion of a blend of antioxidants, and substantial improvements were seen in hair color. The antioxidants also preserved the melanin producing cells and their capacity to synthesize melanin.

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Rosemary oil blend reverses grey hair by >50%. An anti-inflammatory / antioxidant herb, this topical serum dramatically reduced the severity of greying hair over a few months. Focus on these, your melanocytes will thank you, and your hair will be colored.

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Antioxidants clinically reverse grey hair. Here, a multiple antioxidant blend again nearly cut in half the severity of hair greying.

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Inflammation is a driver of grey hair. Inflammatory pathways inhibit the genes that are needed to produce melanin for hair color. Anti-inflammatories like: • Aspirin • Taurine • Pregnenolone/progesterone • Red light • Glycine etc should be explored.

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The gut is the major source of inflammation in the body. Luckily, we've got you covered with our gut masterclass here:

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READ THIS IF YOU WANT TO FIX YOUR GUT. If you have IBS, bloating, gas, poor bowel movements or brain fog, you NEED to see this. This is a comprehensive DEEP dive into fixing your digestive health:

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STRESS drives grey hair. We have nerves that connect to hair follicles. The sympathetic nervous system directly drives the depletion of hair-pigment producing cells. If you want to control your stress, you HAVE to check out the thread below.

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High cortisol, anxiety, and can’t sleep? This is for you. This is the ULTIMATE GUIDE to STRESS - the signs, the biological mechanisms and what to do about it:

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Stress (adrenaline + noradrenaline) also kills melanocyte stem cells.

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Analyses have shown that when stress over a lifetime accumulates past a certain point, the hair grays.

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High dose vitamin B5 can reverse premature grey hair. Potentially because B5 is needed to synthesize steroids that oppose the stress response. Cells that multiply at a high rate also need lots of B5.

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PABA can reverse grey hair. I have no experience with it, but PABA was once known as vitamin B10. Older reports show that megadosing PABA can reverse grey hair.

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IGF-1 prevents hair greying. IGF-1 is a growth factor released alongside insulin. It helps to combat the oxidative stress that causes grey hair. It also supports hair growth in general.

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Finally, it's important to consider that pigmentation only happens to hair that is in the growth phase. Thus, fostering hair growth in general should be protective.

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Hair loss doesn't have to be permanent. Here are 7 non-pharmaceutical, clinically backed tools to regrow hair:

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All of these processes are manifestations of your overall, systemic health. If YOU want personalized help from us with your health, click below to book a call now http://www.prism.miami

Prism Health The solution is out there. We can help you find it. prism.miami

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Thank you for reading through this. Give this tweet below a repost if you found it interesting to spread the message.

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GREY HAIR isn't inevitable, it's a sign of aging that you can prevent or even reverse. The science of what causes it, and what you might be able to do to about it:

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Be sure to check out all of our content, supplements, lab testing options and join our email list for exclusive offers here: http://www.analyzeandoptimize.io

Analyze & Optimize | enhanced existence Restoring youth through bioenergetics. Esoteric health information from Analyze & Optimize. analyzeandoptimize.io

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Reversing Gray Hair: Inspiring the Development of New Therapies Through Research on Hair Pigmentation and Repigmentation Progress Hair graying is a common and visible sign of aging resulting from decreased or absence of melanogenesis. Although it has been established that gray hair greatly impacts people's mental health and social life, there is no effective countermeasure ... pmc.ncbi.nlm.nih.gov

Age-induced hair greying - the multiple effects of oxidative stress - PubMed An obvious sign of ageing is hair greying, or the loss of pigment production and deposition within the hair shafts. Numerous mechanisms, acting at different levels and follicular locations, contribute to hair greying, ranging from melanocyte stem cells defects to follicular melanocyte death. One key … pubmed.ncbi.nlm.nih.gov

Premature Graying of Hair: A Comprehensive Review and Recent Insights Hair symbolizes well-being and self-expression, with graying occurring naturally among different racial groups at varying ages. Premature graying has psychological and societal impacts, influencing self-esteem and quality of life. Gray hair usually ... pmc.ncbi.nlm.nih.gov

A Case of Premature Hair Graying Treated with Ferrous Sulfate pmc.ncbi.nlm.nih.gov

Serum iron, zinc, and copper concentration in premature graying of hair - PubMed Premature graying of hair with unclear etiology, which is known as premature canities, is a common cause of referrals to the dermatologists. We assessed the relationship between serum iron, copper, and zinc concentrations with premature canities. This study was conducted on patients under 20 years o … pubmed.ncbi.nlm.nih.gov

Relationship between Trace Elements and Premature Hair Graying Hair is said to gray prematurely when a minimum of five gray hairs occurs before the age of 20 in fair skinned, 25 in Asians, and 30 in Africans. It may be genetically associated with autoimmune syndromes or certain environmental factors. The aim of ... pmc.ncbi.nlm.nih.gov

Epidemiological and Investigative Study of Premature Graying of Hair in Higher Secondary and Pre-University School Children Hair pigmentation is one of the most conspicuous phenotypes in humans ranging from black, brown, and blonde to red. Premature graying of hair occurs more commonly without any underlying pathology but is said to be inherited in autosomal dominant ... pmc.ncbi.nlm.nih.gov

Sci-Hub | Darkening of white hair in Parkinson’s disease. Clinical and Experimental Dermatology, 14(4), 317–318 | 10.1111/j.1365-2230.1989.tb01992.x sci-hub.se

Sci-Hub | PIGMENTATION IN PARKINSON’S DISEASE TREATED WITH LEVODOPA. The Lancet, 301(7794), 97–98 | 10.1016/s0140-6736(73)90490-x sci-hub.se

Successful Treatment of Grey Hairs with High Dose Calcium Pantothenate Successful Treatment of Grey Hairs with High Dose Calcium Pantothenate ijdvl.com

Effect of Grey Hair Evulsion on the Response to Calcium Pantothenate in Premature Grey Hairs - PubMed Thirty nine girls between 12 and 31 years in age, having Premature grey hairs were, treated with calcium pantothenate 200 mg, Basiton Forte. (a vitamin B complex formulation), and/or vitamin E 200 mg a day orally, combined with grey hair evulsion which consists of pulling out all the grey hairs alon … pubmed.ncbi.nlm.nih.gov

Sci-Hub | CLINICAL ACHROMOTRICHIA. Science, 94(2437), 257–258 | 10.1126/science.94.2437.257 sci-hub.se

Sci-Hub | Effect of Calcium Pantothenate and Para-Aminobenzoic Acid on the Gray Hair of Humans. Experimental Biology and Medicine, 53(1), 47–49 | 10.3181/00379727-53-14179p sci-hub.se

Oxidative Stress in Ageing of Hair Experimental evidence supports the hypothesis that oxidative stress plays a major role in the ageing process. Reactive oxygen species are generated by a multitude of endogenous and environmental challenges. Reactive oxygen species or free radicals ... pmc.ncbi.nlm.nih.gov

Premature Graying as a Consequence of Compromised Antioxidant Activity in Hair Bulb Melanocytes and Their Precursors Intricate coordinated mechanisms that govern the synchrony of hair growth and melanin synthesis remain largely unclear. These two events can be uncoupled in prematurely gray hair, probably due to oxidative insults that lead to the death of oxidative ... pmc.ncbi.nlm.nih.gov

Evaluation of Systemic Oxidative Stress in Patients with Premature Canities and Correlation of Severity of Hair Graying with the Degree of Redox Imbalance - PubMed Systemic redox imbalance is present in premature canities patients, with the severity of hair graying varying in parallel to the degree of oxidative stress. Antioxidants supplementation is likely to yield therapeutic benefit in premature canities. pubmed.ncbi.nlm.nih.gov

Anti-Graying Effects of External and Internal Treatments with Luteolin on Hair in Model Mice Little is known about the anti-graying effects of antioxidants on hair. The anti-graying effects of three antioxidants (luteolin, hesperetin, and diosmetin) on hair were investigated according to the sequential processes of hair graying that were ... pmc.ncbi.nlm.nih.gov

A Clinical Evaluation of the Safety, Efficacy, and Tolerability of the Soulflower Rosemary Redensyl Hair Growth Serum, Tetragain™, in Healthy Female Subjects for the Treatment of Alopecia: Promoting Hair Growth and Reducing Gray Hair - PubMed Introduction Alopecia and graying hair, common conditions influenced by aging, genetics, and environmental factors, often see limited success with traditional treatments. Rosemary extract, valued for its antioxidant and anti-inflammatory benefits, has gained attention for promoting hair growth and r … pubmed.ncbi.nlm.nih.gov

Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells - Nature Empirical and anecdotal evidence has associated stress with accelerated hair greying (formation of unpigmented hairs)1,2, but so far there has been little scientific validation of this link. Here we report that, in mice, acute stress leads to hair greying through the fast depletion of melanocyte stem cells. Using a combination of adrenalectomy, denervation, chemogenetics3,4, cell ablation and knockout of the adrenergic receptor specifically in melanocyte stem cells, we find that the stress-induced loss of melanocyte stem cells is independent of immune attack or adrenal stress hormones. Instead, hair greying results from activation of the sympathetic nerves that innervate the melanocyte stem-cell niche. Under conditions of stress, the activation of these sympathetic nerves leads to burst release of the neurotransmitter noradrenaline (also known as norepinephrine). This causes quiescent melanocyte stem cells to proliferate rapidly, and is followed by their differentiation, migration and permanent depletion from the niche. Transient suppression of the proliferation of melanocyte stem cells prevents stress-induced hair greying. Our study demonstrates that neuronal activity that is induced by acute stress can drive a rapid and permanent loss of somatic stem cells, and illustrates an example in which the maintenance of somatic stem cells is directly influenced by the overall physiological state of the organism. Stress induces hair greying in mice through depletion of melanocyte stem cells, which is mediated by the activation of sympathetic nerves rather than through immune attack or adrenal stress hormones. nature.com

Hair and stress: A pilot study of hair and cytokine balance alteration in healthy young women under major exam stress Mouse models show that experimental stress mimicking prolonged life-stress exposure enhances neurogenic inflammation, induces adaptive immunity cytokine-imbalance characterized by a shift to Type 1 T-helper cell cytokines and increases apoptosis of ... pmc.ncbi.nlm.nih.gov

Quantitative mapping of human hair greying and reversal in relation to life stress A method to profile hair pigmentation patterns establishes a new approach for psychobiological studies and links metabolic changes to greying in humans. elifesciences.org

Sci-Hub | IGF-1 resist oxidative damage to HaCaT and depigmentation in mice treated with H 2 O 2. Biochemical and Biophysical Research Communications | 10.1016/j.bbrc.2018.07.004 sci-hub.se

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GREY HAIR driven by nutrients, thyroid Low B12 and hypothyroidism are closely tied to premature hair greying. B12 - animal foods (oysters, meat, milk, organs) Thyroid support - see below

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The ultimate supplement to boost your metabolism: THYROID HORMONE - A complete guide 1. Symptoms you may be hypothyroid Just to name a few: • ALWAYS being tired • Feeling COLD, especially at the extremities • Slow / lethargic speech • Stubborn weight gain • Poor mood

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Posted - April 4, 2025 at 2:39 PM

Saved - May 14, 2025 at 8:09 AM

reSee.it AI Summary

The conversation discusses the link between stress and grey hair, noting that stress depletes hair-pigment producing cells and kills melanocyte stem cells. Accumulated stress over time leads to greying. High doses of vitamin B5 and PABA may reverse premature greying, as B5 helps synthesize steroids that counter stress. IGF-1, a growth factor, combats oxidative stress and supports hair growth. The discussion emphasizes that hair pigmentation occurs only during the growth phase, highlighting the importance of overall systemic health for hair color.

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STRESS drives grey hair. We have nerves that connect to hair follicles. The sympathetic nervous system directly drives the depletion of hair-pigment producing cells. If you want to control your stress, you HAVE to check out the thread below.

@Outdoctrination - Analyze & Optimize

High cortisol, anxiety, and can’t sleep? This is for you. This is the ULTIMATE GUIDE to STRESS - the signs, the biological mechanisms and what to do about it:

@Outdoctrination - Analyze & Optimize

Stress (adrenaline + noradrenaline) also kills melanocyte stem cells.

@Outdoctrination - Analyze & Optimize

Analyses have shown that when stress over a lifetime accumulates past a certain point, the hair grays.

@Outdoctrination - Analyze & Optimize

High dose vitamin B5 can reverse premature grey hair. Potentially because B5 is needed to synthesize steroids that oppose the stress response. Cells that multiply at a high rate also need lots of B5.

@Outdoctrination - Analyze & Optimize

PABA can reverse grey hair. I have no experience with it, but PABA was once known as vitamin B10. Older reports show that megadosing PABA can reverse grey hair.

@Outdoctrination - Analyze & Optimize

IGF-1 prevents hair greying. IGF-1 is a growth factor released alongside insulin. It helps to combat the oxidative stress that causes grey hair. It also supports hair growth in general.

@Outdoctrination - Analyze & Optimize

Finally, it's important to consider that pigmentation only happens to hair that is in the growth phase. Thus, fostering hair growth in general should be protective.

@Outdoctrination - Analyze & Optimize

Hair loss doesn't have to be permanent. Here are 7 non-pharmaceutical, clinically backed tools to regrow hair:

@Outdoctrination - Analyze & Optimize

All of these processes are manifestations of your overall, systemic health. If YOU want personalized help from us with your health, click below to book a call now http://www.prism.miami

Prism Health The solution is out there. We can help you find it. prism.miami

@Outdoctrination - Analyze & Optimize

Thank you for reading through this. Give this tweet below a repost if you found it interesting to spread the message.

@Outdoctrination - Analyze & Optimize

GREY HAIR isn't inevitable, it's a sign of aging that you can prevent or even reverse. The science of what causes it, and what you might be able to do to about it: